How accurate is magnetic resonance imaging of brain function?

Trends in Neurosciences

Volumn 26, Issue 2, 2003, Pages 108-114

  Uǧurbil, Kâmil ^a   Toth, Louis ^b   Kim, Dae Shik ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYGLUCOSE; DEOXYHEMOGLOBIN;

ACCURACY; BRAIN BLOOD VESSEL; BRAIN FUNCTION; BRAIN MAPPING; BRAIN METABOLISM; BRAIN PERFUSION; ELECTRIC ACTIVITY; HEMODYNAMICS; IMAGING SYSTEM; METHODOLOGY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OXYGEN CONSUMPTION; PRIORITY JOURNAL; REVIEW;

BRAIN; CEREBROVASCULAR CIRCULATION; COGNITION; ECHO-PLANAR IMAGING; HUMANS; MAGNETIC RESONANCE IMAGING; NERVE NET; NEURONS; OXYGEN; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 0037303913     PISSN: 01662236     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-2236(02)00039-5     Document Type: Review

References (67)

1. Kennedy C., et al. The ocular dominance columns of the striate cortex as studied by the deoxyglucose method for measurement of local cerebral glucose utilization. Trans. Am. Neurol. Assoc. 100:1975;74-77.
2. Bandettini P.A., et al. Time course EPI of human brain function during task activation. Magn. Reson. Med. 25:1992;390-397.
3. Kwong K.K., et al. Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation. Proc. Natl. Acad. Sci. U. S. A. 89:1992;5675-5679.
4. Ogawa S., et al. Intrinsic signal changes accompanying sensory stimulation: functional brain mapping with magnetic resonance imaging. Proc. Natl. Acad. Sci. U. S. A. 89:1992;5951-5955.
5. Edelman R.E., et al. Quantitative mapping of cerebral blood flow and functional localization with echo-planar MR imaging and signal targeting with alternating radio frequency. Radiology. 192:1994;513-520.
6. Kim S.-G. Quantification of relative cerebral blood flow change by flow-sensitive alternating inversion recovery (FAIR) technique: application to functional mapping. Magn. Reson. Med. 34:1995;293-301.
7. Barbier E.L., et al. Methodology of brain perfusion imaging. J. Magn. Reson. Imaging. 13:2001;496-520.
8. Aguirre G.K., et al. Experimental design and the relative sensitivity of BOLD and perfusion fMRI. Neuroimage. 15:2002;488-500.
9. Mandeville J.B., et al. Dynamic functional imaging of relative cerebral blood volume during rat forepaw stimulation. Magn. Reson. Med. 39:1998;615-624.
10. Mandeville J.B., et al. Regional sensitivity and coupling of BOLD and CBV changes during stimulation of rat brain. Magn. Reson. Med. 45:2001;443-447.
11. Leite F.P., et al. Repeated fMRI using iron oxide contrast agent in awake, behaving macaques at 3 Tesla. Neuroimage. 16:2002;283-294.
12. Fujita I., et al. Columns for visual features of objects in monkey inferotemporal cortex. Nature. 360:1992;343-346.
13. Wang G., et al. Optical imaging of functional organization in the monkey inferotemporal cortex. Science. 272:1996;1665-1668.
14. Kim D.-S., et al. Ultra-high field (7T) mapping of the human ventral visual area for 'head-from-motion'. Neuroimage. 13:2001;S901.
15. Kanwisher N., Wojciulik E. Visual attention: insights from brain imaging. Nat. Rev. Neurosci. 1:2000;91-100.
16. Sereno M.I., et al. Borders of multiple visual areas in humans revealed by functional magnetic resonance imaging. Science. 268:1995;889-893.
17. DeYoe E.A., et al. Mapping striate and extrastriate visual areas in human cerebral cortex. Proc. Natl. Acad. Sci. U. S. A. 93:1996;2382-2386.
18. Engel S.A., et al. Retinotopic organization in human visual cortex and the spatial precision of functional MRI. Cereb. Cortex. 7:1997;181-192.
19. Menon R.S., et al. Ocular dominance in human V1 demonstrated by functional magnetic resonance imaging. J. Neurophysiol. 77:1997;2780-2787.
20. Menon R.S., Goodyear B.G. Submillimeter functional localization in human striate cortex using BOLD contrast at 4 Tesla: implications for the vascular point-spread function. Magn. Reson. Med. 41:1999;230-235.
21. Cheng K., et al. Human ocular dominance columns as revealed by high-field functional magnetic resonance imaging. Neuron. 32:2001;359-374.
22. Goodyear B.G., Menon R.S. Brief visual stimulation allows mapping of ocular dominance in visual cortex using fMRI. Hum. Brain Mapp. 14:2001;210-217.
23. Duong Q.D., et al. Spatio-temporal dynamics of BOLD fMRI signals: towards mapping submillimeter cortical columns using the early negative response. Magn. Reson. Med. 44:2000;231-242.
24. Kim D.S., et al. High-resolution mapping of iso-orientation columns by fMRI. Nat. Neurosci. 3:2000;164-169.
25. Bonhoeffer T., Grinvald A. The layout of iso-orientation domains in area 18 of cat visual cortex: optical imaging reveals a pinwheel-like organization. J. Neurosci. 13:1993;4157-4180.
26. Toth L.J., et al. Spatial correlation of BOLD activity with neuronal responses. Soc. Neurosci. Abstr. 783.1:2001.
27. Menon R.S., et al. 4 Tesla gradient recalled echo characteristics of photic stimulation- induced signal changes in the human primary visual cortex. Magn. Reson. Med. 30:1993;380-386.
28. Iadecola C., et al. Local and propagated vascular responses evoked by focal synaptic activity in cerebellar cortex. J. Neurophysiol. 78:1997;651-659.
29. Tsekos N.V., et al. Quantitative measurements of cerebral blood flow in rats using the FAIR technique: correlation with previous iodoantipyrine autoradiographic studies. Magn. Reson. Med. 39:1998;564-573.
30. Thulborn K.R., et al. Oxygenation dependence of the transverse relaxation time of water protons in whole blood at high field. Biochim. Biophys. Acta. 714:1982;265-270.
31. Lee S.-P., et al. Diffusion weighted spin-echo fMRI at 9.4 T: microvascular/tissue contribution to BOLD signal changes. Mag. Reson. Med. 42:1999;919-928.
32. Duong T.Q., et al. Functional MRI of calcium-dependent synaptic activity: cross correlation with CBF and BOLD measurements. Magn. Reson. Med. 43:2000;383-392.
33. Lin Y.J., Koretsky A.P. Manganese ion enhances T1-weighted MRI during brain activation: an approach to direct imaging of brain function. Magn. Reson. Med. 38:1997;378-388.
34. Duong T.Q., et al. Localized cerebral blood flow response at submillimeter columnar resolution. Proc. Natl. Acad. Sci. U. S. A. 98:2001;10904-10909.
35. 2 on cerebral blood volume, blood flow, and vascular mean transit time. Stroke. 5:1974;630-639.
36. Boxerman J.L., et al. MR contrast due to intravascular magnetic susceptibility perturbations. Magn. Reson. Med. 34:1995;555-556.
37. Ogawa S., et al. Functional brain mapping by blood oxygenation level-dependent contrast magnetic resonance imaging. Biophys. J. 64:1993;800-812.
38. van Zijl P.C., et al. Quantitative assessment of blood flow, blood volume and blood oxygenation effects in functional magnetic resonance imaging. Nat. Med. 4:1998;159-167.
39. Uǧurbil K., et al. Functional Mapping in the human brain using high magnetic fields. Philos. Trans. R. Soc. London Ser. B. 354:1999;1195-1213.
40. Uǧurbil K., et al. Magnetic resonance studies of brain function and neurochemistry. Annu. Rev. Biomed. Eng. 2:2000;633-660.
41. Pawlik G., et al. Quantitative capillary topography and blood flow in the cerebral cortex of cats: an in vivo microscopic study. Brain Res. 208:1981;35-58.
42. Thulborn K.R., et al. Dependence of the transverse relaxation time of water protons in whole blood at high field. Biochem. Biophys. Acta. 714:1992;265-272.
43. Barth M., Moser E. Proton NMR relaxation times of human blood samples at 1.5 T and implications for functional MRI. Cell Mol. Biol. 43:1997;783-791.
44. Mildner T., et al. A qualitative test of the balloon model for BOLD-based MR signal changes at 3T. Magn. Reson. Med. 46:2001;891-899.
45. +ATPase, NADPH-diaphorase, nitric oxide synthase, and N-methyl-D-aspartate receptor subunit 1. Neuroscience. 83:1998;1025-1045.
46. 17O in live mice by proton NMR. NMR Biomed. 10:1997;333-340.
47. 17O relaxation time and NMR sensitivity of cerebral water and their field dependence. Magn. Reson. Med. 45:2001;543-549.
48. 17O NMR approach for fast imaging of cerebral metabolic rate of oxygen in rat brain at high field. Proc. Natl. Acad. Sci. U. S. A. 99:2002;13194-13199.
49. Grinvald A., et al. High-resolution optical imaging of functional brain architecture in the awake monkey. Proc. Natl. Acad. Sci. U. S. A. 88:1991;11559-11563.
50. Malonek D., et al. Vascular imprints of neuronal activity: relationships between the dynamics of cortical blood flow, oxygenation, and volume changes following sensory stimulation. Proc. Natl. Acad. Sci. U. S. A. 94:1997;14826-14831.
51. Venzetta I., Grinvald A. Phosphorescence decay measurements in cat visual cortex show early blood oxygenation level decrease in response to visual stimulation. Neurosci. Lett. 51(Suppl.):1998;S42.
52. Vanzetta I., Grinvald A. Increased cortical oxidative metabolism due to sensory stimulation: implications for functional brain imaging. Science. 286:1999;1555-1558.
53. Grinvald A., et al. Non-invasive visualization of cortical columns by fMRI. Nat. Neurosci. 3:2000;105-107.
54. Menon R.S., et al. BOLD based functional MRI at 4 Tesla includes a capillary bed contribution: echo-planar imaging correlates with previous optical imaging using intrinsic signals. Magn. Reson. Med. 33:1995;453-459.
55. Hu X., et al. Evaluation of the early response in fMRI using short stimulus duration. Magn. Reson. Med. 37:1997;877-884.
56. Twieg D.B., et al. Estimating fast response onset time. Proc. Int. Soc. Magn. Reson. Med. 3:1997;1645.
57. Yacoub E., et al. Further evaluation of the initial negative response in functional magnetic resonance imaging. Magn. Reson. Med. 41:1999;436-441.
58. Yacoub E., et al. Observation of the initial 'dip' in fMR1 signal in human visual cortex at 7 Tesla. Proc. Intl. Soc. Mag. Reson. Med. 8:2000;991.
59. Cannestra A.F., et al. Temporal spatial differences observed by functional MRI and human intraoperative optical imaging. Cereb. Cortex. 11:2001;773-782.
60. Yacoub E., et al. Investigation of the initial dip in fMRI at 7 Tesla. NMR Biomed. 14:2001;408-412.
61. Logothetis N.K., et al. Functional imaging of the monkey brain. Nat. Neurosci. 2:1999;555-560.
62. Arthurs O.J., Boniface S. How well do we understand the neural origins of the fMRI BOLD signal? Trends Neurosci. 25:2002;27-31.
63. Mathiesen C., et al. Modification of activity-dependent increases of cerebral blood flow by excitatory synaptic activity and spikes in rat cerebellar cortex. J. Physiol. 512:1998;555-566.
64. Mathiesen C., et al. Temporal coupling between neuronal activity and blood flow in rat cerebellar cortex as indicated by field potential analysis. J. Physiol. 523:2000;235-246.
65. Lauritzen M. Relationship of spikes, synaptic activity, and local changes of cerebral blood flow. J. Cereb. Blood Flow Metab. 21:2001;1367-1383.
66. Logothetis N.K., et al. Neurophysiological investigation of the basis of the fMRI signal. Nature. 412:2001;150-157.
67. Duong T.Q., et al. High-resolution, spin-echo BOLD, and CBF fMRI at 4 and 7 T. Magn. Reson. Med. 48:2002;589-593.