Adrenomedullin stimulates proliferation and inhibits apoptosis of immature rat thymocytes cultured in vitro

Peptides

Volumn 24, Issue 2, 2003, Pages 295-300

  Belloni, Anna S ^a   Trejter, Marcin ^b   Malendowicz, Ludwik K ^b   Nussdorfer, Gastone G ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

Author keywords

Adrenomedullin; Apoptosis; Cell proliferation; Immature rat; Thymocytes

Indexed keywords

ADRENOMEDULLIN; ADRENOMEDULLIN RECEPTOR; CALCITONIN RECEPTOR; MESSENGER RNA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; THYMOCYTE;

EID: 0037301474     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0196-9781(03)00038-X     Document Type: Article

References (51)

1. Albertin G., Forneris M., Aragona F., Nussdorfer G.G. Expression of adrenomedullin and its receptors in the human adrenal cortex and aldosteronomas. Int. J. Mol. Med. 8:2001;423-426.
2. Andreis P.G., Albertin G., Conconi M.T., Carraro G., Malendowicz L.K., Ziolkowska A.et al. Evidence for an autocrine-paracrine role of adrenomedullin in the cultured rat adrenal zona glomerulosa cells. Int. J. Mol. Med. 10:2002;401-405.
3. Andreis P.G., Markowska A., Champion H.C., Mazzocchi G., Malendowicz L.K., Nussdorfer G.G. Adrenomedullin enhances cell proliferation and deoxyribonucleic acid synthesis in rat adrenal zona glomerulosa: receptor subtype involved and signaling mechanism. Endocrinology. 141:2000;2098-2104.
4. Belloni A.S., Andreis P.G., Rossi G.P., Mingrino A., Champion H.C., Kadowitz P.J.et al. Inhibitory effect of adrenomedullin (ADM) on the aldosterone response of human adrenocortical cells to angiotensin-II: role of ADM(22-52)-sensitive receptors. Life Sci. 63:1998;2313-2321.
5. Belloni A.S., Albertin G., Forneris M., Nussdorfer G.G. Proadrenomedullin derived peptides as autocrine-paracrine regulators of cell growth. Histol. Histopathol. 16:2001;1263-1274.
6. Cuttitta F., Pio R., Garayoa M., Zudaire E., Julian M., Elsasser T.H.et al. Adrenomedullin functions as an important tumor survival factor in human carcinogenesis. Microsc. Res. Tech. 57:2002;110-119.
7. Eto T. A reviews of the biological properties and clinical implications of adrenomedullin and proadrenomedullin N-terminal 20 peptide (PAMP), hypotensive and vasodilating peptides. Peptides. 22:2001;1693-1711.
8. Forneris M., Gottardo L., Albertin G., Malendowicz L.K., Nussdorfer G.G. Expression and function of adrenomedullin and its receptors in Conn's adenoma cells. Int. J. Mol. Med. 8:2001;675-679.
9. Garayoa M., Bodegas E., Cuttitta F. Adrenomedullin in mammalian embryogenesis. Microsc. Res. Tech. 57:2002;40-57.
10. Hay D.L., Smith D.M. Adrenomedullin receptors: molecular identity and function. Peptides. 22:2001;1753-1763.
11. Hinson J.P., Kapas S., Smith D.M. Adrenomedullin, a multifunctional regulatory peptide. Endocr. Rev. 21:2000;138-167.
12. Horio T., Nishikimi T., Yoshihara F., Nagaya N., Matsuo H., Takishita S.et al. Production and secretion of adrenomedullin in cultured rat cardiac myocytes and nonmyocytes: stimulation by IL-1β and TNF-α Endocrinology. 139:1998;4576-4580.
13. Isumi Y., Minamino N., Katafuchi T., Yoshioka M., Tsuji T., Kangawa K.et al. Adrenomedullin production in fibroblasts: its possible function as a growth regulator of Swiss 3T3 cells. Endocrinology. 139:1998;2552-2563.
14. Iwasaki H., Eguchi S., Shichiri M., Marumo F., Hirata Y. Adrenomedullin as a novel growth-promoting factor for cultured vascular smooth muscle cells: role of tyrosine kinase-mediated mitogen-activated protein kinase activation. Endocrinology. 139:1998;3432-3441.
15. Iwasaki H., Shichiri M., Marumo F., Hirata Y. Adrenomedullin stimulates proline-rich tyrosine kinase 2 in vascular smooth muscle cells. Endocrinology. 142:2001;564-572.
16. Juaneda C., Dumont Y., Quirion R. The molecular pharmacology of CGRP and related peptide receptor subtypes. Trends Pharmacol. Sci. 21:2000;432-438.
17. Kapas S., Bansal A., Bhargava V., Maher R., Malli D., Hagi-Pavli E.et al. Adrenomedullin expression in pathogen-challenged oral epithelial cells. Peptides. 22:2001;1485-1489.
18. Kapas S., Brown D.W., Farthing P.M., Hagi P.E. Adrenomedullin has mitogenic effects of human oral keratinocytes: involvement of cyclic AMP. FEBS Lett. 418:1997;287-290.
19. Kapas S., Teuchini M.L., Farthing P.M. Regulation of adrenomedullin secretion in cultured human skin and oral keratinocytes. J. Invest. Dermatol. 117:2001;353-359.
20. Kato H., Shichiri M., Marumo F., Hirata Y. Adrenomedullin as an autocrine/paracrine apoptosis survival factor for rat endothelial cells. Endocrinology. 138:1997;2615-2620.
21. Kitamura K., Kangawa K., Kawamoto M., Ichiki Y., Nakamura S., Matsuo H.et al. Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma. Biochem. Biophys. Res. Commun. 192:1993;553-560.
22. Kitamura K., Kato J., Kawamoto M., Tanaka M., Chino N., Kangawa K.et al. The intermediate form of glycine-extended adrenomedullin is the major circulating molecular form in human plasma. Biochem. Biophys. Res. Commun. 244:1998;551-555.
23. Kubo A., Minamino N., Isumi Y., Kangawa K., Dohi K., Matsuo H. Adrenomedullin production is correlated with differentiation in human leukemia cell lines and peripheral blood monocytes. FEBS Lett. 426:1998;233-237.
24. Kubo A., Minamino N., Isumi Y., Katafuchi T., Kangawa K., Dohi K.et al. Production of adrenomedullin in macrophage cell line and peritoneal macrophage. J. Biol. Chem. 273:1998;16730-16738.
25. Malendowicz L.K., Brelinska R., De Caro R., Trejter M., Nussdorfer G.G. Endothelin-1, acting via the A receptor subtype, stimulates thymocyte proliferation in the rat. Life Sci. 62:1998;1959-1963.
26. Malendowicz L.K., Trejter M., De Caro R., Jedrzejczak N., Brelinska R., Markowska A.et al. Cholecystokinin, acting through the A receptor subtype, stimulates the proliferative activity of adrenocortical cells and thymocytes in the rat. Histol. Histopathol. 14:1999;439-443.
27. Martinez A., Elsasser T.H., Muro C.C., Moody T.W., Miller M.J., Macri C.J.et al. Expression of adrenomedullin and its receptor in normal and malignant human skin: a potential pluripotent role in the integument. Endocrinology. 138:1997;5597-5604.
28. Mazzocchi G., Rossi G.P., Malendowicz L.K., Champion H.C., Nussdorfer G.G. Endothelin-1[1-31], acting as an ETA-receptor selective agonist, stimulates proliferation of cultured rat zona glomerulosa cells. FEBS Lett. 487:2000;194-198.
29. Mazzocchi G., Rossi G.P., Neri G., Malendowicz L.K., Albertin G., Nussdorfer G.G. 11β-Hydroxysteroid dehydrogenase expression and activity in the human adrenal cortex. FASEB J. 12:1998;1533-1539.
30. Miller M.J., Martinez A., Unsworth E.J., Thiele C.J., Moody T.W., Elsasser T.et al. Adrenomedullin expression in human tumor cell lines. Its potential role as an autocrine growth factor. J. Biol. Chem. 271:1996;23345-23351.
31. Moody T.W., Miller M.J., Martinez A., Unsworth E., Cuttitta F. Adrenomedullin binds with high affinity, elevates cyclic AMP, and stimulates c-fos mRNA in C6 glioma cells. Peptides. 18:1997;1111-1115.
32. Nakayama M., Takahashi K., Kitamuro T., Murakami O., Shirato K., Shibahara S. Transcriptional control of adrenomedullin induction by phorbol ester in human monocytic leukemia cells. Eur. J. Biochem. 267:2000;3559-3566.
33. Nakayama M., Takahashi K., Murakami O., Murakami H., Sasano H., Shirato K.et al. Adrenomedullin in monocytes and macrophages: possible involvement of macrophage-derived adrenomedullin in atherogenesis. Clin. Sci. 97:1999;247-251.
34. Nussdorfer G.G. Proadrenomedullin-derived peptides in the paracrine control of the hypothalamo-pituitary-adrenal axis. Int. Rev. Cytol. 206:2001;249-284.
35. Oehler M.K., Norbury C., Hague S., Rees M.C., Bicknell R. Adrenomedullin inhibits hypoxic cell death by upregulation of Bcl-2 in endometrial cancer cells: a possible promotion mechanism for tumour growth. Oncogene. 20:2001;2937-2945.
36. Parameswaran N., Spielman W.S., Brooks D.P., Nambi P. SB203580 reverses adrenomedullin effect on proliferation and apoptosis in cultured mesangial cells. Eur. J. Pharmacol. 371:1999;75-82.
37. Rebuffat P., Forneris M.L., Aragona F., Ziolkowska A., Malendowicz L.K., Nussdorfer G.G. Adrenomedullin and its receptors are expressed in the zona glomerulosa of human adrenal gland: evidence that ADM enhances proliferation and decreases apoptosis in cultured ZG cells. Int. J. Mol. Med. 9:2002;119-124.
38. Rocchi P., Boudouresque F., Zamora A.J., Muracciole X., Lechevallier E., Martin P.M.et al. Expression of adrenomedullin and peptide amidation activity in human prostate cancer and human prostate cancer cell lines. Cancer Res. 61:2001;1196-1206.
39. Samson W.K. Adrenomedullin and the control of fluid and electrolyte homeostasis. Annu. Rev. Physiol. 61:1999;363-390.
40. Sata M., Kakoki M., Nagata D., Nishimatsu H., Suzuki E., Aoyagi T.et al. Adrenomedullin and nitric oxide inhibit human endothelial cell apoptosis via a cyclic GMP-independent mechanism. Hypertension. 36:2000;83-88.
41. Semplicini A., Ceolotto G., Baritono E., Malendowicz L.K., Andreis P.G., Sartori M.et al. Adrenomedullin stimulates DNA synthesis of rat adrenal zona glomerulosa cells through activation of the mitogen-activated protein kinase-dependent cascade. J. Hypertens. 19:2001;599-602.
42. Shichiri M., Kato H., Doi M., Marumo F., Hirata Y. Induction of max by adrenomedullin and calcitonin gene-related peptide antagonizes endothelial apoptosis. Mol. Endocrinol. 13:1999;1353-1363.
43. Shimokubo T., Sakata J., Kitamura K., Kangawa K., Matsuo H., Eto T. Augmented adrenomedullin concentration in right ventricle and plasma of experimental pulmonary hypertension. Life Sci. 57:1995;1771-1779.
44. Shoji H., Minamino N., Kangawa K., Matsuo H. Endotoxin markedly elevates plasma concentration and gene transcription of adrenomedullin in rat. Biochem. Biophys. Res. Commun. 215:1995;531-537.
45. Sugo S., Minamino N., Shoji H., Kangawa K., Kitamura K., Eto T.et al. IL-1, TNF, and lipopolysaccharide additively stimulate production of adrenomedullin in vascular smooth muscle cells. Biochem. Biophys. Res. Commun. 207:1995;25-32.
46. Thomson L.M., Kapas S., Carroll M., Hinson J.P. Autocrine role of adrenomedullin in the human adrenal cortex. J. Endocrinol. 170:2001;259-265.
47. Tomoda Y., Isumi Y., Katafuchi T., Minamino N. Regulation of adrenomedullin secretion from cultured cells. Peptides. 22:2001;1783-1794.
48. Trejter M., Brelinska R., Warchol J.B., Butowska W., Neri G., Rebuffat P.et al. Effects of galanin on proliferation and apoptosis of immature rat thymocytes. Int. J. Mol. Med. 10:2002;183-186.
49. Trejter M., Warchol J.B., De Caro R., Brelinska R., Nussdorfer G.G., Malendowicz L.K. Studies on the involvement of endogenous neuropeptides in the control of thymocyte proliferation in the rat. Histol. Histopathol. 16:2001;155-158.
50. Withers D.J., Coppock H.A., Seufferlein T., Smith D.M., Bloom S.R., Rozengurt E. Adrenomedullin stimulates DNA synthesis and cell proliferation via elevation of cAMP in Swiss 3T3 cells. FEBS Lett. 378:1996;83-87.
51. Zhou M., Chaudry I.H., Wang P. The small intestine is an important source of adrenomedullin release during polymicrobial sepsis. Am. J. Physiol. 281:2001;R654-R660.