Adrenomedullin stimulates DNA synthesis and cell proliferation via elevation of cAMP in Swiss 3T3 cells

FEBS Letters

Volumn 378, Issue 1, 1996, Pages 83-87

  Withers, Dominic J ^a,b   Coppock, Hedley A ^b   Seufferlein, Thomas ^a   Smith, David M ^b   Bloom, Stephen R ^b   Rozengurt, Enrique ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

Growth control; Neuropeptide; Signal transduction

Indexed keywords

ADRENOMEDULLIN; CALCIUM; CYCLIC AMP; INSULIN; PROTEIN KINASE C;

ANIMAL CELL; ARTICLE; CELL MUTANT; CELL PROLIFERATION; CELL STRAIN 3T3; CONTROLLED STUDY; DNA SYNTHESIS; DRUG RECEPTOR BINDING; MITOGENESIS; MOUSE; PRIORITY JOURNAL;

EID: 0030029424     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-5793(95)01427-6     Document Type: Article

References (22)

1. Kitamura, K., Kangawa, K., Kawamoto, M., Ichiki, Y., Nakamura, S., Hisayuki, M. and Eto, Y. (1993) Biochem. Biophys. Res. Commun. 192, 553-560.
2. Sakata, J., Shimokubo, T., Kitamura, K., Nakamura, S., Kangawa, K., Matsuo, H. and Eto, T. (1993) Biochem. Biophys. Res. Commun. 195, 921-927.
3. Ichiki, Y., Kitamura, K., Kangawa, K., Kawamoto, M., Matsuo, H. and Eto, T. (1994) FEBS Lett. 338, 6-10.
4. Owji, A.A., Smith, D.M., Coppock, H.A., Morgan, D.G.A., Bhogal, R., Ghatei, M.A. and Bloom, S.R. (1995) Endocrinology 136, 2127-2134.
5. Shimekake, Y., Nagata, K., OHta S., Kambayashi, Y., Teroaka, H., Kitamura, K., Eto, T., Kangawa, K. and Matsuo, H. (1995) J. Biol. Chem. 270, 4412-4417.
6. Zimmerman, U., Fischer, J.A. and Muff, R. (1995) Peptides 16, 421-424.
7. Kapas, S., Catt, K.J. and Clark, A.J.L. (1995) J. Biol. Chem. 270, 25344-25347.
8. Nuki, C., Kawasaki, H., Kitamura, K., Takenaga, M., Kangawa, K., Eto, T. and Wada, A. (1993) Biochem. Biophys. Res. Commun. 196, 245-251.
9. Dohlman, H.G., Caron, M.G. and Lefkowitz, R.J. (1987) Biochemistry 26, 2657-2664.
10. Rozengurt, E. (1986) Science 234, 161-166.
11. Withers, D.J., Bloom, S.R. and Rozengurt, E. (1995) J. Biol. Chem. 270, 21411-21419.
12. Fracker, P.J. and Speck, J.C. (1978) Biochem. Biophys. Res. Commun. 80, 849-857.
13. Bhogal, R., Smith, D.M., Purkiss, P. and Bloom, S.R. (1993) Endocrinology 133, 2351-2361.
14. Sinnet-Smith, J., Zachary, I., Valverde, A.M. and Rozengurt, E. (1993) J. Biol. Chem. 268, 22060-22065.
15. Seufferlein, T., Withers, D.J., Broad, S., Herget, T., Walsh, J.H. and Rozengurt, E. (1995) Cell Growth Diff. 6, 383-393.
16. Rozengurt, E. (1995) Polypeptide and neuropeptide growth factors: signalling pathways and role in cancer. In: Oxford Textbook of Oncology (Peckham, M., Pimedo, H. and Veronesi, U., Eds.), pp. 12-20.
17. Rozengurt E. and Sinnet-Smith, J. (1983) Proc. Natl. Acad. Sci. USA 80, 2936-2940.
18. Nanberg, E. and Rozengurt, E. (1988) EMBO J. 7, 2741-2748.
19. Rozengurt, E. (1995) Cancer Surveys 24, 81-96.
20. Zachary, I., Masters, S.B. and Bourne, H.R. (1990) Biochem. Biophys. Res. Commun. 168, 1184-1193.
21. Tokumitsu, H., Chijiwa, T., Hagiwara, M., Mizutani, A., Terasawa, M. and Hidaka, H. (1990) J. Biol. Chem. 265, 4315-4320.
22. Rozengurt, E. (1992) Curr. Opin. Cell. Biol. 4, 161-165.