Identification of a new Pyk2 target protein with Arf-GAP activity

Molecular and Cellular Biology

Volumn 19, Issue 3, 1999, Pages 2338-2350

  Andreev, J ^a,b   Simon, J P ^b   Sabatini, D D ^b   Kam, J ^c   Plowman, G ^d   Randazzo, P A ^c   Schlessinger, J ^a,b  

^a NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

^d SUGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANKYRIN; FOCAL ADHESION KINASE 2; GUANINE NUCLEOTIDE BINDING PROTEIN; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CELLULAR DISTRIBUTION; COMPLEX FORMATION; ENZYME ACTIVATION; GOLGI COMPLEX; IMMUNOFLUORESCENCE; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN INTERACTION; PROTEIN ISOLATION; PROTEIN LOCALIZATION; SACCHAROMYCES CEREVISIAE;

ANIMALIA; SACCHAROMYCES CEREVISIAE;

EID: 0033019056     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.19.3.2338     Document Type: Article

References (63)

1. Aoe, T., E. Cukierman, A. Lee, D. Cassel, P. J. Peters, and V. W. Hsu. 1997. The KDEL receptor, ERD2, regulates intracellular traffic by recruiting a GTPase-activating protein for Arf1. EMBO J. 16:7305-7316.
2. Aronheim, A. 1997. Improved efficiency Sos recruitment system: expression of the mammalian GAP reduces isolation of Ras GTPase false positives. Nucleic Acids Res. 25:3373-3374.
3. Aronheim, A., E. Zandi, H. Hennemann, S. J. Elledge, and M. Karin. 1997. Isolation of an AP-1 repressor by a novel method for detecting protein-protein interactions. Mol. Cell. Biol. 17:3094-3102.
4. Astier, A., S. N. Manie, H. Avraham, H. Hirai, S. F. Law, Y. Zhang, E. A. Golemis, Y. Fu, B. J. Druker, N. Haghayeghi, A. S. Freedman, and S. Avraham. 1997. The related focal adhesion tyrosine kinase differentially phosphorylates p130Cas and the Cas-like protein, p105HEF1. J. Biol. Chem. 272:19719-19724.
5. Austin, C. D., and D. Shields. 1996. Formation of nascent secretory vesicles from the trans-Golgi network of endocrine cells is inhibited by tyrosine kinase and phosphatase inhibitors. J. Cell Biol. 135:1471-1483.
6. Barnekow, A., R. Jahn, and M. Schartl. 1990. Synaptophysin: a substrate for the protein tyrosine kinase pp60c-src in intact synaptic vesicles. Oncogene 5:1019-1024.
7. Batzer, A. G., D. Rotin, J. M. Urena, E. Y. Skolnik, and J. Schlessinger. 1994. Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor. Mol. Cell. Biol. 14:5192-5201.
8. Bomsel, M., and K. Mostov. 1992. Role of heterotrimeric G proteins in membrane traffic. Mol. Biol. Cell. 3:1317-1328.
9. Brown, M., J. Andrade, H. Radhakrishna, J. Donaldson, J. Cooper, and P. Randazzo. 1998. ASAP1, a phospholipid-dependent Arf GTPase-activating protein that associates with and is phosphorylated by Src. Mol. Cell. Biol. 18:7038-7051.
10. Buccione, R., S. Bannykh, I. Santone, M. Baldassarre, F. Facchiano, Y. Bozzi, G. Di Tullio, A. Mironov, A. Luini, and M. A. De Matteis. 1996. Regulation of constitutive exocytic transport by membrane receptors. A biochemical and morphometric study. J. Biol. Chem. 271:3523-3533.
11. Cavenagh, M. M., J. A. Whitney, K. Carroll, C. Zhang, A. L. Boman, A. G. Rosenwald, I. Mellman, and R. A. Kahn. 1996. Intracellular distribution of Arf proteins in mammalian cells. Arf6 is uniquely localized to the plasma membrane. J. Biol. Chem. 271:21767-21774.
12. Chardin, P., S. Paris, B. Antonny, S. Robineau, S. Beraud-Dufour, C. L. Jackson, and M. Chabre. 1996. A human exchange factor for Arf contains Sec7-and pleckstrin-homology domains. Nature 384:481-484.
13. Chen, C., and H. Okayama. 1987. High-efficiency transformation of mammalian cells by plasmid DNA. Mol. Cell. Biol. 7:2745-2752.
14. Cukierman, E., I. Huber, M. Rotman, and D. Cassel. 1995. The Arf1 GT-Pase-activating protein: zinc finger motif and Golgi complex localization. Science 270:1999-2002.
15. D'Souza-Schorey, C., G. Li, M. I. Colombo, and P. D. Stahl. 1995. A regulatory role for Arf6 in receptor-mediated endocytosis. Science 267:1175-1178.
16. De Camilli, P., S. D. Emr, P. S. McPherson, and P. Novick. 1996. Phosphoinositides as regulators in membrane traffic. Science 271:1533-1539.
17. Dikic, I., G. Tokiwa, S. Lev, S. A. Courtneidge, and J. Schlessinger. 1996. A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation. Nature 383:547-550.
18. Donaldson, J. G., and R. D. Klausner. 1994. Arf: a key regulatory switch in membrane traffic and organelle structure. Curr. Opin. Cell. Biol. 6:527-532.
19. Exton, J. H. 1997. New developments in phospholipase D. J. Biol. Chem. 272:15579-15582.
20. Faundez, V., J. T. Horng, and R. B. Kelly. 1998. A function for the AP3 coat complex in synaptic vesicle formation from endosomes. Cell 93:423-432.
21. Feng, S., J. K. Chen, H. Yu, J. A. Simon, and S. L. Schreiber. 1994. Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions. Science 266:1241-1247.
22. Foster-Barber, A., and J. M. Bishop. 1998. Src interacts with dynamin and synapsin in neuronal cells. Proc. Natl. Acad. Sci. USA 95:4673-4677.
23. Frank, S., S. Upender, S. H. Hansen, and J. E. Casanova. 1998. ARNO is a guanine nucleotide exchange factor for ADP-ribosylation factor 6. J. Biol. Chem. 273:23-27.
24. Galisteo, M. L., J. Chernoff, Y. C. Su, E. Y. Skolnik, and J. Schlessinger. 1996. The adaptor protein Nck links receptor tyrosine kinases with the serine-threonine kinase Pak1. J. Biol. Chem. 271:20997-21000.
25. Gietz, R. D., R. H. Schiestl, A. R. Willems, and R. A. Woods. 1995. Studies on the transformation of intact yeast cells by the LiAc/SS-DNA/PEG procedure. Yeast 11:355-360.
26. Goda, Y., and T. C. Sudhof. 1997. Calcium regulation of neurotransmitter release: reliably unreliable? Curr. Opin. Cell Biol. 9:513-518.
27. Gorr, S. 1996. Differential storage of prolactin, granins (chromogranin B and secretogranin II), and constitutive secretory markers in rat pituitary GH4C1 cells. J. Biol. Chem. 271:3575-3580.
28. Hadari, Y. R., H. Kouhara, I. Lax, and J. Schlessinger. 1998. Binding of Shp2 tyrosine phosphatase to FRS2 is essential for FGF-induced PC12 cell differentiation. Mol. Cell. Biol. 18:3966-3973.
29. Helms, J. B., and J. E. Rothman. 1992. Inhibition by brefeldin A of a Golgi membrane enzyme that catalyses exchange of guanine nucleotide bound to Arf. Nature 360:352-354.
30. Ireland, L. S., G. C. Johnston, M. A. Drebot, N. Dhillon, J. A. DeMaggio, M. F. Hoekstra, and R. A. Singer. 1994. A member of a novel family of "Zn-finger" proteins mediates the transition from stationary phase to cell proliferation. EMBO J. 13:3812-3821.
31. Isakoff, S. J., T. Cardozo, J. Andreev, A. Aronheim, M. Lemmon, and E. Y. Skolnik. 1998. Identification and analysis of PH domain containing 3-phosphoinositide binding proteins using a novel in vivo assay in yeast. EMBO J. 17:5374-5387.
32. Janz, R., and T. C. Sudhof. 1998. Cellugyrin, a novel ubiquitous form of synaptogyrin that is phosphorylated by pp60c-src. J. Biol. Chem. 273:2851-2857.
33. Kahn, R. A., and A. G. Gilman. 1986. The protein cofactor necessary for ADP ribosylation of Gs by cholera toxin is itself a GTP binding protein. J. Biol. Chem. 261:7906-7911.
34. Kahn, R. A., F. G. Kern, J. Clark, E. P. Gelmann, and C. Rulka. 1991. Human ADP-ribosylation factors. A functionally conserved family of GTP binding proteins. J. Biol. Chem. 266:2606-2614.
35. Kahn, R. A., T. Terui, and P. A. Randazzo. 1996. Effects of acid phospholipids on Arf activities: potential roles in membrane traffic. J. Lipid Mediat. Cell. Signal. 14:209-214.
36. Klarlund, J. K., L. E. Rameh, L. C. Cantley, J. M. Buxton, J. J. Holik, C. Sakelis, V. Patki, S. Corvera, and M. P. Czech. 1998. Regulation of GRP1-catalyzed ADP ribosylation factor guanine nucleotide exchange by phosphatidylinositol 3,4,5-trisphosphate. J. Biol. Chem. 273:1859-1862.
37. 2+-induced regulation of ion channel and MAP kinase functions. Nature 376:737-745.
38. Li, J., H. Avraham, R. A. Rogers, S. Raja, and S. Avraham. 1996. Characterization of RAFTK, a novel focal adhesion kinase, and its integrin-dependent phosphorylation and activation in megakaryocytes. Blood 88:417-428.
39. Li, W., P. Hu, E. Y. Skolnik, A. Ullrich, and J. Schlessinger. 1992. The SH2 and SH3 domain-containing Nck protein is oncogenic and a common target for phosphorylation by different surface receptors. Mol. Cell. Biol. 12:5824-5833.
40. Li, X., and H. S. Earp. 1997. Paxillin is tyrosine-phosphorylated by and preferentially associates with the calcium-dependent tyrosine kinase in rat liver epithelial cells. J. Biol. Chem. 272:14341-14348.
41. Linstedt, A. D., M. L. Vetter, J. M. Bishop, and R. B. Kelly. 1992. Specific association of the proto-oncogene product pp60c-src with an intracellular organelle, the PC12 synaptic vesicle. J. Cell Biol. 117:1077-1084.
42. Makler, V., E. Cukierman, M. Rotman, A. Admon, and D. Cassel. 1995. ADP-ribosylation factor-directed GTPase-activating protein. Purification and partial characterization. J. Biol. Chem. 270:5232-5237.
43. Meacci, E., S. C. Tsai, R. Adamik, J. Moss, and M. Vaughan. 1997. Cytohesin-1, a cytosolic guanine nucleotide-exchange protein for ADP-ribosylation factor. Proc. Natl. Acad. Sci. USA 94:1745-1748.
44. Mitchell, R., D. McCulloch, E. Lutz, M. Johnson, C. MacKenzie, M. Fennell, G. Fink, W. Zhou, and S. C. Sealfon. 1998. Rhodopsin-family receptors associate with small G proteins to activate phospholipase D. Nature 392: 411-414.
45. Neet, K., and T. Hunter. 1996. Vertebrate nonreceptor protein-tyrosine kinase families. Genes Cells 1:147-169.
46. Ohashi, M. K., R. Jan deVries, R. Frank, G. Snoek, V. Bankaitis, K. Wirtz, and W. B. Huttner. 1995. A role for phosphatidylinositol transfer protein in secretory vesicle formation. Nature 377:544-547.
47. Poon, P. P., X. Wang, M. Rotman, I. Huber, E. Cukierman, D. Cassel, R. A. Singer, and G. C. Johnston. 1996. Saccharomyces cerevisiae Gcs1 is an ADP ribosylation factor GTPase activating protein. Proc. Natl. Acad. Sci. USA 93:10074-10077.
48. Radhakrishna, H., and J. G. Donaldson. 1997. ADP-ribosylation factor 6 regulates a novel plasma membrane recycling pathway. J. Cell Biol. 139:49-61.
49. Randazzo, P. A. 1997. Functional interaction of ADP-ribosylation factor 1 with phosphatidylinositol 4,5-bisphosphate. J. Biol. Chem. 272:7688-7692.
50. Randazzo, P. A. 1997. Resolution of two ADP-ribosylation factor 1 GTPase-activating proteins from rat liver. Biochem. J. 324:413-419.
51. Randazzo, P. A., and R. A. Kahn. 1994. GTP hydrolysis by ADP-ribosylation factor is dependent on both an ADP-ribosylation factor GTPase-activating protein and acid phospholipids. J. Biol. Chem. 269:10758-10763.
52. Randazzo, P. A., O. Weiss, and R. A. Kahn. 1992. Preparation of recombinant ADP-ribosylation factor. Methods Enzymol. 219:362-369.
53. Rickles, R. J., M. C. Botfield, X. M. Zhou, P. A. Henry, J. S. Brugge, and M. J. Zoller. 1995. Phage display selection of ligand residues important for Src homology 3 domain binding specificity. Proc. Natl. Acad. Sci. USA 92:10909-10913.
54. Rothman, J. E., and L. Orci. 1992. Molecular dissection of the secretory pathway. Nature 355:409-415.
55. Sabatini, D. D., M. Adesnik, I. E. Ivanov, and J. P. Simon. 1996. Mechanism of formation of post-Golgi vesicles from TGN membranes: Arf-dependent coat assembly and PKC-regulated vesicle scission. Biocell 20:287-300.
56. Schlaepfer, D. D., and T. Hunter. 1998. Integrin signaling and tyrosine phosphorylation: just the FAKs? Trends Cell Biol. 8:151-157.
57. Schlessinger, J. 1995. Cellular signaling by receptor tyrosine kinases. Harvey Lectures Ser. 89:105-123.
58. Schlessinger, J. 1994. SH2/SH3 signaling proteins. Curr. Opin. Gen. Dev. Biol. 4:25-30.
59. Simon, J. P., I. E. Ivanov, M. Adesnik, and D. D. Sabatini. 1996. The production of post-Golgi vesicles requires a protein kinase C-like molecule, but not its phosphorylating activity. J. Cell Biol. 135:355-70.
60. Simon, J. P., I. E. Ivanov, B. Shopsin, D. Hersh, M. Adesnik, and D. D. Sabatini. 1996. The in vitro generation of post-Golgi vesicles carrying viral envelope glycoproteins requires an Arf-like GTP-binding protein and a protein kinase C associated with the Golgi apparatus. J. Biol. Chem. 271:16952-16961.
61. Smith, D. B., and K. S. Johnson. 1988. Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase. Gene 67:31-40.
62. Stenberg, P. E., T. I. Pestina, R. J. Barrie, and C. W. Jackson. 1997. The Src family kinases, Fgr, Fyn, Lck, and Lyn, colocalize with coated membranes in platelets. Blood 89:2384-2393.
63. Thomas, S. M., and J. S. Brugge. 1997. Cellular functions regulated by Src family kinases. Annu. Rev. Cell. Dev. Biol. 13:513-609.