메뉴 건너뛰기




Volumn 8, Issue 1, 2003, Pages 87-97

Acute and chronic endothelial dysfunction: Implications for the development of heart failure

Author keywords

cAMP; Downregulation; eNOS; iNOS; L arginine; Nitric oxide; Oxygen radicals

Indexed keywords

ALLOPURINOL; AMLODIPINE; ANTIOXIDANT; ARGININE; ASCORBIC ACID; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; CYTOKINE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; SPIRONOLACTONE;

EID: 0037230940     PISSN: 13824147     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1022151106019     Document Type: Review
Times cited : (42)

References (118)
  • 2
    • 0032534496 scopus 로고    scopus 로고
    • Regular physical exercise corrects endothelial dysfunction and improves exercise capacity in patients with chronic heart failure
    • Hambrecht R, Fiehn E, Weigl C, Gielen S, Hamann C, Kaiser R, Yu J, Adams V, Niebauer J, Schuler G. Regular physical exercise corrects endothelial dysfunction and improves exercise capacity in patients with chronic heart failure. Circulation 1998;98:2709-2715.
    • (1998) Circulation , vol.98 , pp. 2709-2715
    • Hambrecht, R.1    Fiehn, E.2    Weigl, C.3    Gielen, S.4    Hamann, C.5    Kaiser, R.6    Yu, J.7    Adams, V.8    Niebauer, J.9    Schuler, G.10
  • 3
    • 0020133458 scopus 로고
    • Alterations in vasomotor tone in congestive heart failure
    • Zelis R, Flaim SF. Alterations in vasomotor tone in congestive heart failure. Prog Cardiovasc Dis 1982;24:437-459.
    • (1982) Prog Cardiovasc Dis , vol.24 , pp. 437-459
    • Zelis, R.1    Flaim, S.F.2
  • 4
    • 0025951502 scopus 로고
    • Endothelium-dependent vasodilation is attenuated in patients with heart failure
    • Kubo SH, Rector TS, Bank AJ, Williams RE, Heifetz SM. Endothelium-dependent vasodilation is attenuated in patients with heart failure. Circulation 1991;84:1589-1596.
    • (1991) Circulation , vol.84 , pp. 1589-1596
    • Kubo, S.H.1    Rector, T.S.2    Bank, A.J.3    Williams, R.E.4    Heifetz, S.M.5
  • 5
    • 0022492202 scopus 로고
    • Norepinephrine spillover to plasma in patients with congestive heart failure: Evidence of increased overall and cardiorenal sympathetic nervous activity
    • Hasking GJ, Esler MD, Jennings GL, Burton D, Johns JA, Korner PI. Norepinephrine spillover to plasma in patients with congestive heart failure: Evidence of increased overall and cardiorenal sympathetic nervous activity. Circulation 1986;73:615-621.
    • (1986) Circulation , vol.73 , pp. 615-621
    • Hasking, G.J.1    Esler, M.D.2    Jennings, G.L.3    Burton, D.4    Johns, J.A.5    Korner, P.I.6
  • 6
    • 0024271086 scopus 로고
    • Sequential neurohumoral measurements in patients with congestive heart failure
    • Francis GS, Rector TS, Cohn JN. Sequential neurohumoral measurements in patients with congestive heart failure. Am Heart J 1988;116:1464-1468.
    • (1988) Am Heart J , vol.116 , pp. 1464-1468
    • Francis, G.S.1    Rector, T.S.2    Cohn, J.N.3
  • 7
    • 0023198721 scopus 로고
    • Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor
    • Palmer RM, Ferrige AG, Moncada S. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 1987;327:524-526.
    • (1987) Nature , vol.327 , pp. 524-526
    • Palmer, R.M.1    Ferrige, A.G.2    Moncada, S.3
  • 8
    • 0023505509 scopus 로고
    • Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide
    • Ignarro LJ, Buga GM, Wood KS, Byrns RE, Chaudhuri G. Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide. Proc Natl Acad Sci USA 1987;84:9265-9269.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 9265-9269
    • Ignarro, L.J.1    Buga, G.M.2    Wood, K.S.3    Byrns, R.E.4    Chaudhuri, G.5
  • 9
    • 0019195506 scopus 로고
    • The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
    • Furchgott RF, Zawadzki JV. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 1980;288:373-376.
    • (1980) Nature , vol.288 , pp. 373-376
    • Furchgott, R.F.1    Zawadzki, J.V.2
  • 11
    • 0022516979 scopus 로고
    • Flow-induced release of endothelium-derived relaxing factor
    • Rubanyi GM, Romero JC, Vanhoutte PM. Flow-induced release of endothelium-derived relaxing factor. Am J Physiol 1986;250:H1145-H1149.
    • (1986) Am J Physiol , vol.250
    • Rubanyi, G.M.1    Romero, J.C.2    Vanhoutte, P.M.3
  • 12
    • 0027752805 scopus 로고
    • The L-arginine-nitric oxide pathway
    • Moncada S, Higgs A. The L-arginine-nitric oxide pathway. N Engl J Med 1993;329:2002-2012.
    • (1993) N Engl J Med , vol.329 , pp. 2002-2012
    • Moncada, S.1    Higgs, A.2
  • 14
    • 0029127216 scopus 로고
    • Endogenous and exogenous nitric oxide inhibits norepinephrine release from rat heart sympathetic nerves
    • Schwarz P, Diem R, Dun NJ, Forstermann U. Endogenous and exogenous nitric oxide inhibits norepinephrine release from rat heart sympathetic nerves. Circ Res 1995;77:841-848.
    • (1995) Circ Res , vol.77 , pp. 841-848
    • Schwarz, P.1    Diem, R.2    Dun, N.J.3    Forstermann, U.4
  • 16
    • 0030603619 scopus 로고    scopus 로고
    • Tumour necrosis factor and inducible nitric oxide synthase in dilated cardiomyopathy
    • Habib FM, Springal DR, Davies GJ, Oakley CM, Yacoub MH, Polak JM. Tumour necrosis factor and inducible nitric oxide synthase in dilated cardiomyopathy. Lancet 1996;347:1151-1155.
    • (1996) Lancet , vol.347 , pp. 1151-1155
    • Habib, F.M.1    Springal, D.R.2    Davies, G.J.3    Oakley, C.M.4    Yacoub, M.H.5    Polak, J.M.6
  • 18
    • 0028092958 scopus 로고
    • Nitric oxide synthases: Roles, tolls, and controls
    • Nathan C, Xie QW. Nitric oxide synthases: Roles, tolls, and controls. Cell 1994;78:915-918.
    • (1994) Cell , vol.78 , pp. 915-918
    • Nathan, C.1    Xie, Q.W.2
  • 19
    • 85047678254 scopus 로고
    • Systemic vasoconstriction induced by inhibition of nitric oxide synthesis is attenuated in conscious dogs with heart failure
    • Elsner D, Muntze A, Kromer EP, Reigger GAA. Systemic vasoconstriction induced by inhibition of nitric oxide synthesis is attenuated in conscious dogs with heart failure. Cardiovasc Res 1991;25:438-440.
    • (1991) Cardiovasc Res , vol.25 , pp. 438-440
    • Elsner, D.1    Muntze, A.2    Kromer, E.P.3    Reigger, G.A.A.4
  • 20
    • 0024512621 scopus 로고
    • Heart failure depresses endothelium-dependent responses in canine femoral artery
    • Kaiser L, Spickard RC, Oliver NB. Heart failure depresses endothelium-dependent responses in canine femoral artery. Am J Physiol 1989;256:H962-H967.
    • (1989) Am J Physiol , vol.256
    • Kaiser, L.1    Spickard, R.C.2    Oliver, N.B.3
  • 22
    • 0346557031 scopus 로고
    • Myocardial hypertrophy and failure: Association between alterations in the production or release of EDRF/NO and myocardial dysfunction
    • In: Bevan J, Kaley G, Rubayani G, eds.
    • Hintze TH, Wang J, Seyedi N, Wolin M. Myocardial hypertrophy and failure: Association between alterations in the production or release of EDRF/NO and myocardial dysfunction. In: Bevan J, Kaley G, Rubayani G, eds. Flow-Dependent Regulation of Vascular Function. 1995.
    • (1995) Flow-Dependent Regulation of Vascular Function
    • Hintze, T.H.1    Wang, J.2    Seyedi, N.3    Wolin, M.4
  • 23
    • 0030026755 scopus 로고    scopus 로고
    • Coronary B-adrenoreceptor function is modified by the endothelium in heart failure
    • Larosa G, Forrester C. Coronary B-adrenoreceptor function is modified by the endothelium in heart failure. J Vasc Res 1996;33:62-70.
    • (1996) J Vasc Res , vol.33 , pp. 62-70
    • Larosa, G.1    Forrester, C.2
  • 24
    • 0027156408 scopus 로고
    • Cardiorenal and neurohumoral function in a canine model of early left ventricular dysfunction
    • Redfield MM, Aarhus LL, Wright RS, Burnett JC. Cardiorenal and neurohumoral function in a canine model of early left ventricular dysfunction. Circulation 1993;87:2016-2022.
    • (1993) Circulation , vol.87 , pp. 2016-2022
    • Redfield, M.M.1    Aarhus, L.L.2    Wright, R.S.3    Burnett, J.C.4
  • 25
    • 0029051606 scopus 로고
    • Selective impairment of vagal-mediated NO dependent coronary vasodilation in conscious dogs after pacing induced heart failure
    • Zhao G, Shen W, Xu X, Ochoa M, Bernstein R. Hintze TH. Selective impairment of vagal-mediated NO dependent coronary vasodilation in conscious dogs after pacing induced heart failure. Circulation 1995;91:2655-2663.
    • (1995) Circulation , vol.91 , pp. 2655-2663
    • Zhao, G.1    Shen, W.2    Xu, X.3    Ochoa, M.4    Bernstein, R.5    Hintze, T.H.6
  • 26
    • 0027978812 scopus 로고
    • Role of endothelium-derived relaxing factor in parasympathetic coronary vasodilation following carotid chemoreflex activation in conscious dogs
    • Shen W, Wang J, Ochoa M, Xu X, Hintze TH. Role of endothelium-derived relaxing factor in parasympathetic coronary vasodilation following carotid chemoreflex activation in conscious dogs. Am J Physiol 1994;267:H605-613.
    • (1994) Am J Physiol , vol.267
    • Shen, W.1    Wang, J.2    Ochoa, M.3    Xu, X.4    Hintze, T.H.5
  • 27
    • 0033030241 scopus 로고    scopus 로고
    • Kinin-mediated coronary nitric oxide production contributes to the therapeutic actions of ACE and NEP inhibitors and amlodipine in the treatment of heart failure
    • Zhang X, Recchia F, Bernstein RD, Xu X, Nasjletti Hintze TH. Kinin-mediated coronary nitric oxide production contributes to the therapeutic actions of ACE and NEP inhibitors and amlodipine in the treatment of heart failure. JPET 1999;288:742-751.
    • (1999) JPET , vol.288 , pp. 742-751
    • Zhang, X.1    Recchia, F.2    Bernstein, R.D.3    Xu, X.4    Nasjletti5    Hintze, T.H.6
  • 29
    • 0032539036 scopus 로고    scopus 로고
    • Reduced nitric oxide production and altered myocardial metabolism during the decompensation of pacing-induced heart failure in conscious dogs
    • Recchia FA, McConnell PI, Bernstein RD, Vogel TR, Xu XB, Hintze TH. Reduced nitric oxide production and altered myocardial metabolism during the decompensation of pacing-induced heart failure in conscious dogs. Circ Res 1998;83:969-979.
    • (1998) Circ Res , vol.83 , pp. 969-979
    • Recchia, F.A.1    McConnell, P.I.2    Bernstein, R.D.3    Vogel, T.R.4    Xu, X.B.5    Hintze, T.H.6
  • 33
    • 0036344032 scopus 로고    scopus 로고
    • cAMP signal transduction: A potential compensatory pathway for coronary endothelial nitric oxide production after heart failure
    • Zhang X, Tada H, Wang Z, Hintze TH. cAMP signal transduction: A potential compensatory pathway for coronary endothelial nitric oxide production after heart failure. ATVB 2002;22:1273-1278.
    • (2002) ATVB , vol.22 , pp. 1273-1278
    • Zhang, X.1    Tada, H.2    Wang, Z.3    Hintze, T.H.4
  • 34
    • 0027491127 scopus 로고
    • Chronic exercise enhances endothelium-mediated dilation of epicardial coronary artery in conscious dogs
    • Wang J, Wolin MS, Hintze TH. Chronic exercise enhances endothelium-mediated dilation of epicardial coronary artery in conscious dogs. Circ Res 1993;73:829-838.
    • (1993) Circ Res , vol.73 , pp. 829-838
    • Wang, J.1    Wolin, M.S.2    Hintze, T.H.3
  • 35
    • 0029841677 scopus 로고    scopus 로고
    • Function and production of nitric oxide in the coronary circulation of the conscious dog during exercise
    • Bernstein RD, Ochoa FY, Xu X, Forfia P, Shen W, Thompson CI, Hintze TH. Function and production of nitric oxide in the coronary circulation of the conscious dog during exercise. Circ Res 1996;79:840-848.
    • (1996) Circ Res , vol.79 , pp. 840-848
    • Bernstein, R.D.1    Ochoa, F.Y.2    Xu, X.3    Forfia, P.4    Shen, W.5    Thompson, C.I.6    Hintze, T.H.7
  • 36
    • 0030989850 scopus 로고    scopus 로고
    • Exercise training enhances reflex cholinergic, NO dependent coronary dilation in conscious dogs
    • Zhao G, Zhang X, Xu X, Ochoa M, Hintze TH. Exercise training enhances reflex cholinergic, NO dependent coronary dilation in conscious dogs. Circ Res 1997;80:868-876.
    • (1997) Circ Res , vol.80 , pp. 868-876
    • Zhao, G.1    Zhang, X.2    Xu, X.3    Ochoa, M.4    Hintze, T.H.5
  • 37
    • 0028118896 scopus 로고
    • Chronic exercise in dogs increases coronary vascular nitric oxide production and endothelial nitric oxide gene expression
    • Sessa WC, Pritchard K, Seyedi N, Wang J, Hintze TH. Chronic exercise in dogs increases coronary vascular nitric oxide production and endothelial nitric oxide gene expression. Circ Res 1994;74:349-353.
    • (1994) Circ Res , vol.74 , pp. 349-353
    • Sessa, W.C.1    Pritchard, K.2    Seyedi, N.3    Wang, J.4    Hintze, T.H.5
  • 38
    • 0034688194 scopus 로고    scopus 로고
    • Effect of an angiotensin-converting-enzyme inhibitor, ramapril, on cardiovascular events in high-risk patients
    • Yusuf S, Sleight P, Pogue J, Bosch J, Davies R, Dagenais G. Effect of an angiotensin-converting-enzyme inhibitor, ramapril, on cardiovascular events in high-risk patients. N Engl J Med 2000;342:201-202.
    • (2000) N Engl J Med , vol.342 , pp. 201-202
    • Yusuf, S.1    Sleight, P.2    Pogue, J.3    Bosch, J.4    Davies, R.5    Dagenais, G.6
  • 39
    • 0031014498 scopus 로고    scopus 로고
    • ACE inhibitors stimulate nitric oxide production to modulate myocardial oxygen consumption
    • Zhang X, Xie Y, Nasjletti A, Xu X, Wolin MS, Hintze TH. ACE inhibitors stimulate nitric oxide production to modulate myocardial oxygen consumption. Circulation 1997;95:176-182.
    • (1997) Circulation , vol.95 , pp. 176-182
    • Zhang, X.1    Xie, Y.2    Nasjletti, A.3    Xu, X.4    Wolin, M.S.5    Hintze, T.H.6
  • 41
    • 0031912146 scopus 로고    scopus 로고
    • Amlodipine releases nitric oxide from canine coronary microvessels-an unexpected mechanism of action of a calcium-channel blocking agent
    • Zhang X, Hintze TH. Amlodipine releases nitric oxide from canine coronary microvessels-an unexpected mechanism of action of a calcium-channel blocking agent. Circulat 1998;97:576-580.
    • (1998) Circulat , vol.97 , pp. 576-580
    • Zhang, X.1    Hintze, T.H.2
  • 43
    • 0031451344 scopus 로고    scopus 로고
    • Inhibition of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase blocks hypoxia-mediated downregulation of endothelial nitric oxide synthase
    • Lauf U, LaFata V, Liao JK. Inhibition of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase blocks hypoxia-mediated downregulation of endothelial nitric oxide synthase. J Biol Chem 1997;272:31725-31729.
    • (1997) J Biol Chem , vol.272 , pp. 31725-31729
    • Lauf, U.1    LaFata, V.2    Liao, J.K.3
  • 45
    • 0033839002 scopus 로고    scopus 로고
    • Simvastatin acts synergistically with ACE inhibitors and amlodipine to decrease oxygen consumption in the rat heart
    • Mital S, Magneson A, Loke KE, Liao J, Forfia P, Hintze TH. Simvastatin acts synergistically with ACE inhibitors and amlodipine to decrease oxygen consumption in the rat heart. J Cardiovas Pharm 2000;36:248-254.
    • (2000) J Cardiovas Pharm , vol.36 , pp. 248-254
    • Mital, S.1    Magneson, A.2    Loke, K.E.3    Liao, J.4    Forfia, P.5    Hintze, T.H.6
  • 46
    • 4243379774 scopus 로고    scopus 로고
    • Preservation of NO production by stains: A new therapy for the treatment of heart failure
    • (abstract)
    • Trochu J-N, Mital S, Xu X, Ochoa M, Liao J, Recchia FA, Hintze TH. Preservation of NO production by stains: A new therapy for the treatment of heart failure. FASEB J 2001;15:A783 (abstract).
    • (2001) FASEB J , vol.15
    • Trochu, J.-N.1    Mital, S.2    Xu, X.3    Ochoa, M.4    Liao, J.5    Recchia, F.A.6    Hintze, T.H.7
  • 48
    • 0033542476 scopus 로고    scopus 로고
    • Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosporylation
    • Dimmler S, Fleming I, Fisslthaler B, Hermann C, Busse R, Zeiher AM. Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosporylation. Nature 1999;399:601-605.
    • (1999) Nature , vol.399 , pp. 601-605
    • Dimmler, S.1    Fleming, I.2    Fisslthaler, B.3    Hermann, C.4    Busse, R.5    Zeiher, A.M.6
  • 49
    • 0028231301 scopus 로고
    • Nitric oxide: Mediator, murderer, and medicine
    • Anggard E. Nitric oxide: Mediator, murderer, and medicine. Lancet 1994;343:1199-1206.
    • (1994) Lancet , vol.343 , pp. 1199-1206
    • Anggard, E.1
  • 50
    • 0028093149 scopus 로고
    • Effects of L-arginine on impaired acetylcholine-induced and ischemic vasodilation of the forearm in patients with heart failure
    • Hirooka Y, Imaizumi T, Tagawa T, Shiramoto M, Endo T, Ando S, Takeshita A. Effects of L-arginine on impaired acetylcholine-induced and ischemic vasodilation of the forearm in patients with heart failure. Circulation 1994;90:658-668.
    • (1994) Circulation , vol.90 , pp. 658-668
    • Hirooka, Y.1    Imaizumi, T.2    Tagawa, T.3    Shiramoto, M.4    Endo, T.5    Ando, S.6    Takeshita, A.7
  • 52
    • 0032951856 scopus 로고    scopus 로고
    • Effects of L-arginine on lower limb vasodilator reserve and exercise capacity in patients with chronic heart failure
    • Kanaya Y, Nakamura M, Kobayashi N, Hiramori K. Effects of L-arginine on lower limb vasodilator reserve and exercise capacity in patients with chronic heart failure. Heart 1999;81:512-517.
    • (1999) Heart , vol.81 , pp. 512-517
    • Kanaya, Y.1    Nakamura, M.2    Kobayashi, N.3    Hiramori, K.4
  • 53
    • 0033996620 scopus 로고    scopus 로고
    • Effects of oral administration of L-arginine on renal function in patients with heart failure
    • Watanabe G, Tomiyama H, Doba N. Effects of oral administration of L-arginine on renal function in patients with heart failure. J Hypertens 2000;18:229-234.
    • (2000) J Hypertens , vol.18 , pp. 229-234
    • Watanabe, G.1    Tomiyama, H.2    Doba, N.3
  • 54
    • 0029993977 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled study of supplemental oral L-arginine in patients with heart failure
    • Rector TS, Bank AJ, Mullen KA, Tschumperlin LK, Sih R, Pillai K, Kubo SH. Randomized, double-blind, placebo-controlled study of supplemental oral L-arginine in patients with heart failure. Circulation 1996;93:2135-2141.
    • (1996) Circulation , vol.93 , pp. 2135-2141
    • Rector, T.S.1    Bank, A.J.2    Mullen, K.A.3    Tschumperlin, L.K.4    Sih, R.5    Pillai, K.6    Kubo, S.H.7
  • 55
    • 0034162915 scopus 로고    scopus 로고
    • Correction of endothelial dysfunction in chronic heart failure: Additional effects of exercise training and oral L-arginine supplementation
    • Hambrecht R, Hilbrich L, Erbs S, Gielen S, Fiehn E, Schoene N, Schuler G. Correction of endothelial dysfunction in chronic heart failure: Additional effects of exercise training and oral L-arginine supplementation. J Am Coll Cardiol 2000;35:706-713.
    • (2000) J Am Coll Cardiol , vol.35 , pp. 706-713
    • Hambrecht, R.1    Hilbrich, L.2    Erbs, S.3    Gielen, S.4    Fiehn, E.5    Schoene, N.6    Schuler, G.7
  • 56
    • 0029871489 scopus 로고    scopus 로고
    • Dietary supplementation with L-arginine fails to restore endothelial function in forearm resistance arteries of patients with severe heart failure
    • Chin-Dusting JP, Kaye DM, Lefkovits J, Wong J, Bergin P, Jennings GL. Dietary supplementation with L-arginine fails to restore endothelial function in forearm resistance arteries of patients with severe heart failure. J Am Coll Cardiol 1996;27:1207-1213.
    • (1996) J Am Coll Cardiol , vol.27 , pp. 1207-1213
    • Chin-Dusting, J.P.1    Kaye, D.M.2    Lefkovits, J.3    Wong, J.4    Bergin, P.5    Jennings, G.L.6
  • 57
    • 0027524594 scopus 로고
    • Nitric oxide synthesis inhibition induces leukocyte adhesion via superoxide and mast cells
    • Kubes P, Kanwar S, Niu XF, Gaboury JP. Nitric oxide synthesis inhibition induces leukocyte adhesion via superoxide and mast cells. FASEB J 1993;7:1293-1299.
    • (1993) FASEB J , vol.7 , pp. 1293-1299
    • Kubes, P.1    Kanwar, S.2    Niu, X.F.3    Gaboury, J.P.4
  • 58
    • 0027242030 scopus 로고
    • Hypercholesterolemia increases endothelial superoxide anion production
    • Ohara Y, Peterson TE, Harrison DG. Hypercholesterolemia increases endothelial superoxide anion production. J Clin Invest 1993;91:2546-2551.
    • (1993) J Clin Invest , vol.91 , pp. 2546-2551
    • Ohara, Y.1    Peterson, T.E.2    Harrison, D.G.3
  • 60
    • 0031452440 scopus 로고    scopus 로고
    • A caveolar complex between the cationic amino acid transporter 1 and endothelial nitric-oxide synthase may explain the "arginine paradox"
    • McDonald KK, Zharikov S, Block ER, Kilberg MS. A caveolar complex between the cationic amino acid transporter 1 and endothelial nitric-oxide synthase may explain the "arginine paradox". J Biol Chem 1997;272:31213-31216.
    • (1997) J Biol Chem , vol.272 , pp. 31213-31216
    • McDonald, K.K.1    Zharikov, S.2    Block, E.R.3    Kilberg, M.S.4
  • 61
    • 0032557388 scopus 로고    scopus 로고
    • Increased endogenous nitric oxide synthase inhibitor in patients with congestive heart failure
    • Usui M, Matsuoka H, Miyazaki H, Ueda S, Okuda S, Imaizumi T. Increased endogenous nitric oxide synthase inhibitor in patients with congestive heart failure. Life Sci 1998;62:2425-2430.
    • (1998) Life Sci , vol.62 , pp. 2425-2430
    • Usui, M.1    Matsuoka, H.2    Miyazaki, H.3    Ueda, S.4    Okuda, S.5    Imaizumi, T.6
  • 62
    • 0029670349 scopus 로고    scopus 로고
    • Elevated L-arginine/dimethylarginine ratio contributes to enhanced systemic NO production by dietary L-arginine in hypercholesterolemic rabbits
    • Bode-Boger SM, Boger RH, Kienke S, Junker W, Frolich JC. Elevated L-arginine/dimethylarginine ratio contributes to enhanced systemic NO production by dietary L-arginine in hypercholesterolemic rabbits. Biochem Biophys Res Commun 1996;219:598-603.
    • (1996) Biochem Biophys Res Commun , vol.219 , pp. 598-603
    • Bode-Boger, S.M.1    Boger, R.H.2    Kienke, S.3    Junker, W.4    Frolich, J.C.5
  • 63
    • 0034727706 scopus 로고    scopus 로고
    • In vivo and in vitro evidence for impaired arginine transport in human heart failure
    • Kaye DM, Ahlers BA, Autelitano DJ, Chin-Dusting JP. In vivo and in vitro evidence for impaired arginine transport in human heart failure. Circulation 2000;102:2707-2712.
    • (2000) Circulation , vol.102 , pp. 2707-2712
    • Kaye, D.M.1    Ahlers, B.A.2    Autelitano, D.J.3    Chin-Dusting, J.P.4
  • 65
    • 0029070801 scopus 로고
    • Interactions between L-arginine and L-glutamine change endothelial NO production. An effect independent of NO synthase substrate availability
    • Arnal JF, Munzel T, Venema RC, James NL, Bai CL, Mitch WE, Harrison DG. Interactions between L-arginine and L-glutamine change endothelial NO production. An effect independent of NO synthase substrate availability. J Clin Invest 1995;95:2565-2572.
    • (1995) J Clin Invest , vol.95 , pp. 2565-2572
    • Arnal, J.F.1    Munzel, T.2    Venema, R.C.3    James, N.L.4    Bai, C.L.5    Mitch, W.E.6    Harrison, D.G.7
  • 68
    • 0026561920 scopus 로고
    • Insulin secretion from pancreatic B cells caused by L-arginine-derived nitrogen oxides
    • Schmidt HH, Warner TD, Ishii K, Sheng H, Murad F. Insulin secretion from pancreatic B cells caused by L-arginine-derived nitrogen oxides. Science 1992;255:721-723.
    • (1992) Science , vol.255 , pp. 721-723
    • Schmidt, H.H.1    Warner, T.D.2    Ishii, K.3    Sheng, H.4    Murad, F.5
  • 70
  • 75
    • 0032477685 scopus 로고    scopus 로고
    • Vitamin C improves endothelial function of conduit arteries in patients with chronic heart failure
    • Vitamin C improves endothelial function of conduit arteries in patients with chronic heart failure. Hornig B, Arakawa N, Kohler C, Drexler H. Circulation 1998;97:363-368.
    • (1998) Circulation , vol.97 , pp. 363-368
    • Hornig, B.1    Arakawa, N.2    Kohler, C.3    Drexler, H.4
  • 76
    • 0033587530 scopus 로고    scopus 로고
    • Endothelial dysfunction in chronic myocardial infarction despite increased vascular endothelial nitric oxide synthase and soluble guanylate cyclase expression: Role of enhanced vascular superoxide production
    • Bauersachs J, Bouloumie A, Fraccarollo D, Hu K, Busse R, Ertl G. Endothelial dysfunction in chronic myocardial infarction despite increased vascular endothelial nitric oxide synthase and soluble guanylate cyclase expression: Role of enhanced vascular superoxide production. Circulation 1999;100:292-298.
    • (1999) Circulation , vol.100 , pp. 292-298
    • Bauersachs, J.1    Bouloumie, A.2    Fraccarollo, D.3    Hu, K.4    Busse, R.5    Ertl, G.6
  • 78
    • 0037024270 scopus 로고    scopus 로고
    • Effects of xanthine oxidase inhibition with allopurinol on endothelial function and peripheral blood flow in hyperuricemic patients with chronic heart failure: Results from 2 placebo-controlled studies
    • Doehner W, Schoene N, Rauchhaus M, Leyva-Leon F, Pavitt DV, Reaveley DA, Schuler G, Coats AJ, Anker SD, Hambrecht R. Effects of xanthine oxidase inhibition with allopurinol on endothelial function and peripheral blood flow in hyperuricemic patients with chronic heart failure: Results from 2 placebo-controlled studies. Circulation 2002;105:2619-2624.
    • (2002) Circulation , vol.105 , pp. 2619-2624
    • Doehner, W.1    Schoene, N.2    Rauchhaus, M.3    Leyva-Leon, F.4    Pavitt, D.V.5    Reaveley, D.A.6    Schuler, G.7    Coats, A.J.8    Anker, S.D.9    Hambrecht, R.10
  • 82
    • 0032530589 scopus 로고    scopus 로고
    • Comparison of effects of ascorbic acid on endothelium-dependent vasodilation in patients with chronic congestive heart failure secondary to idiopathic dilated cardiomyopathy versus patients with effort angina pectoris secondary to coronary artery disease
    • Ito K, Akita H, Kanazawa K, Yamada S, Terashima M, Matsuda Y, Yokoyama M. Comparison of effects of ascorbic acid on endothelium-dependent vasodilation in patients with chronic congestive heart failure secondary to idiopathic dilated cardiomyopathy versus patients with effort angina pectoris secondary to coronary artery disease. Am J Cardiol 1998;82:762-767.
    • (1998) Am J Cardiol , vol.82 , pp. 762-767
    • Ito, K.1    Akita, H.2    Kanazawa, K.3    Yamada, S.4    Terashima, M.5    Matsuda, Y.6    Yokoyama, M.7
  • 84
    • 4243442430 scopus 로고    scopus 로고
    • Correction of endothelial dysfunction by vitamin C: Different effects in ischemic heart disease and dilative cardiomyopathy
    • Erbs S, Mobius-Winkler S, Gielen S, Schoene N, Linke A, Schulze PC, Hambrecht R. Correction of endothelial dysfunction by vitamin C: Different effects in ischemic heart disease and dilative cardiomyopathy. Circulation 2000;102:II-55.
    • (2000) Circulation , vol.102
    • Erbs, S.1    Mobius-Winkler, S.2    Gielen, S.3    Schoene, N.4    Linke, A.5    Schulze, P.C.6    Hambrecht, R.7
  • 85
    • 0039550848 scopus 로고    scopus 로고
    • L-Ascorbic acid potentiates nitric oxide synthesis in endothelial cells
    • Heller R, Munscher-Paulig F, Grabner R, Till U. L-Ascorbic acid potentiates nitric oxide synthesis in endothelial cells. J Biol Chem 1999;274:8254-8260.
    • (1999) J Biol Chem , vol.274 , pp. 8254-8260
    • Heller, R.1    Munscher-Paulig, F.2    Grabner, R.3    Till, U.4
  • 86
    • 0032440098 scopus 로고    scopus 로고
    • Ascorbate-dependent enhancement of nitric oxide formation in activated macrophages
    • Mizutani A, Maki H, Torii Y, Hitomi K, Tsukagoshi N. Ascorbate-dependent enhancement of nitric oxide formation in activated macrophages. Nitric Oxide 1998;2:235-241.
    • (1998) Nitric Oxide , vol.2 , pp. 235-241
    • Mizutani, A.1    Maki, H.2    Torii, Y.3    Hitomi, K.4    Tsukagoshi, N.5
  • 87
    • 0025933240 scopus 로고
    • Nitric oxide production by cultured aortic endothelial cells in response to thiol depletion and replenishment
    • Murphy ME, Piper HM, Watanabe H, Sies H. Nitric oxide production by cultured aortic endothelial cells in response to thiol depletion and replenishment. J Biol Chem 1991;266:19378-19383.
    • (1991) J Biol Chem , vol.266 , pp. 19378-19383
    • Murphy, M.E.1    Piper, H.M.2    Watanabe, H.3    Sies, H.4
  • 88
    • 0027104253 scopus 로고
    • Biochemistry of nitric oxide and its redox-activated forms
    • Stamler JS, Singel DJ, Loscalzo J. Biochemistry of nitric oxide and its redox-activated forms. Science 1992;258:1898-1902.
    • (1992) Science , vol.258 , pp. 1898-1902
    • Stamler, J.S.1    Singel, D.J.2    Loscalzo, J.3
  • 89
    • 0018348794 scopus 로고
    • Direct observation of a free radical interaction between vitamin E and vitamin C
    • Packer JE, Slater TF, Willson RL. Direct observation of a free radical interaction between vitamin E and vitamin C. Nature 1979;278:737-738.
    • (1979) Nature , vol.278 , pp. 737-738
    • Packer, J.E.1    Slater, T.F.2    Willson, R.L.3
  • 90
    • 0019414648 scopus 로고
    • Localization of xanthine oxidase in mammary-gland epithelium and capillary endothelium
    • Jarasch ED, Grund C, Bruder G, Heid HW, Keenan TW, Franke WW. Localization of xanthine oxidase in mammary-gland epithelium and capillary endothelium. Cell 1981;25:67-82.
    • (1981) Cell , vol.25 , pp. 67-82
    • Jarasch, E.D.1    Grund, C.2    Bruder, G.3    Heid, H.W.4    Keenan, T.W.5    Franke, W.W.6
  • 91
    • 0034718556 scopus 로고    scopus 로고
    • Crystal structures of bovine milk xanthine dehydrogenase and xanthine oxidase: Structure-based mechanism of conversion
    • Enroth C, Eger BT, Okamoto K, Nishino T, Nishino T, Pai EF. Crystal structures of bovine milk xanthine dehydrogenase and xanthine oxidase: Structure-based mechanism of conversion. Proc Natl Acad Sci USA 2000;97:10723-10728.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 10723-10728
    • Enroth, C.1    Eger, B.T.2    Okamoto, K.3    Nishino, T.4    Nishino, T.5    Pai, E.F.6
  • 92
    • 0024354391 scopus 로고
    • Changes in xanthine oxidase activity in patients with circulatory failure
    • Bakhtiiarov ZA. [Changes in xanthine oxidase activity in patients with circulatory failure]. Ter Arkh 1989;61:68-69.
    • (1989) Ter Arkh , vol.61 , pp. 68-69
    • Bakhtiiarov, Z.A.1
  • 93
  • 95
    • 0033517302 scopus 로고    scopus 로고
    • The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators
    • Pitt B, Zannad F, Remme WJ, Cody R, Castaigne A, Perez A, Palensky J, Wittes J. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. N Engl J Med 1999;341:709-717.
    • (1999) N Engl J Med , vol.341 , pp. 709-717
    • Pitt, B.1    Zannad, F.2    Remme, W.J.3    Cody, R.4    Castaigne, A.5    Perez, A.6    Palensky, J.7    Wittes, J.8
  • 96
    • 0034727695 scopus 로고    scopus 로고
    • Limitation of excessive extracellular matrix turnover may contribute to survival benefit of spironolactone therapy in patients with congestive heart failure: Insights from the randomized aldactone evaluation study (RALES). Rales Investigators
    • Zannad F, Alla F, Dousset B, Perez A, Pitt B. Limitation of excessive extracellular matrix turnover may contribute to survival benefit of spironolactone therapy in patients with congestive heart failure: Insights from the randomized aldactone evaluation study (RALES). Rales Investigators. Circulation 2000;102:2700-2706.
    • (2000) Circulation , vol.102 , pp. 2700-2706
    • Zannad, F.1    Alla, F.2    Dousset, B.3    Perez, A.4    Pitt, B.5
  • 97
    • 0034651798 scopus 로고    scopus 로고
    • Spironolactone increases nitric oxide bioactivity, improves endothelial vasodilator dysfunction, and suppresses vascular angiotensin I/angiotensin II conversion in patients with chronic heart failure
    • Farquharson CA, Struthers AD. Spironolactone increases nitric oxide bioactivity, improves endothelial vasodilator dysfunction, and suppresses vascular angiotensin I/angiotensin II conversion in patients with chronic heart failure. Circulation 2000;101:594-597.
    • (2000) Circulation , vol.101 , pp. 594-597
    • Farquharson, C.A.1    Struthers, A.D.2
  • 98
    • 0037116558 scopus 로고    scopus 로고
    • Addition of spironolactone to angiotensin-converting enzyme inhibition in heart failure improves endothelial vasomotor dysfunction: Role of vascular superoxide anion formation and endothelial nitric oxide synthase expression
    • Bauersachs J, Heck M, Fraccarollo D, Hildemann SK, Ertl G, Wehling M, Christ M. Addition of spironolactone to angiotensin-converting enzyme inhibition in heart failure improves endothelial vasomotor dysfunction: Role of vascular superoxide anion formation and endothelial nitric oxide synthase expression. J Am Coll Cardiol 2002;39:351-358.
    • (2002) J Am Coll Cardiol , vol.39 , pp. 351-358
    • Bauersachs, J.1    Heck, M.2    Fraccarollo, D.3    Hildemann, S.K.4    Ertl, G.5    Wehling, M.6    Christ, M.7
  • 99
    • 0030045652 scopus 로고    scopus 로고
    • Physical training improves endothelial function in patients with chronic heart failure
    • Hornig B, Maier V, Drexler H. Physical training improves endothelial function in patients with chronic heart failure. Circulation 1996;93:210-214.
    • (1996) Circulation , vol.93 , pp. 210-214
    • Hornig, B.1    Maier, V.2    Drexler, H.3
  • 100
    • 0030926448 scopus 로고    scopus 로고
    • Training improves endothelium-dependent vasodilation in resistance vessels of patients with heart failure
    • Katz SD, Yuen J, Bijou R, LeJemtel TH. Training improves endothelium-dependent vasodilation in resistance vessels of patients with heart failure. J Appl Physiol 1997;82:1488-1492.
    • (1997) J Appl Physiol , vol.82 , pp. 1488-1492
    • Katz, S.D.1    Yuen, J.2    Bijou, R.3    Lejemtel, T.H.4
  • 102
    • 0030945318 scopus 로고    scopus 로고
    • Effects of endurance training on mitochondrial ultrastructure and fiber type distribution in skeletal muscle of patients with stable chronic heart failure
    • Hambrecht R, Fiehn E, Yu J, Niebauer J, Weigl C, Hilbrich L, Adams V, Riede U, Schuler G. Effects of endurance training on mitochondrial ultrastructure and fiber type distribution in skeletal muscle of patients with stable chronic heart failure. J Am Coll Cardiol 1997;29:1067-1073.
    • (1997) J Am Coll Cardiol , vol.29 , pp. 1067-1073
    • Hambrecht, R.1    Fiehn, E.2    Yu, J.3    Niebauer, J.4    Weigl, C.5    Hilbrich, L.6    Adams, V.7    Riede, U.8    Schuler, G.9
  • 103
    • 0035137968 scopus 로고    scopus 로고
    • Endothelial dysfunction in patients with chronic heart failure: Systemic effects of lower-limb exercise training
    • Linke A, Schoene N, Gielen S, Hofer J, Erbs S, Schuler G, Hambrecht R. Endothelial dysfunction in patients with chronic heart failure: Systemic effects of lower-limb exercise training. J Am Coll Cardiol 2001;37:392-397.
    • (2001) J Am Coll Cardiol , vol.37 , pp. 392-397
    • Linke, A.1    Schoene, N.2    Gielen, S.3    Hofer, J.4    Erbs, S.5    Schuler, G.6    Hambrecht, R.7
  • 104
    • 0034697756 scopus 로고    scopus 로고
    • Effects of exercise training on left ventricular function and peripheral resistance in patients with chronic heart failure: A randomized trial
    • Hambrecht R, Gielen S, Linke A, Fiehn E, Yu J, Walther C, Schoene N, Schuler G. Effects of exercise training on left ventricular function and peripheral resistance in patients with chronic heart failure: A randomized trial. JAMA 2000;283:3095-3101.
    • (2000) JAMA , vol.283 , pp. 3095-3101
    • Hambrecht, R.1    Gielen, S.2    Linke, A.3    Fiehn, E.4    Yu, J.5    Walther, C.6    Schoene, N.7    Schuler, G.8
  • 105
    • 0030003477 scopus 로고    scopus 로고
    • Contribution of muscle afferents to the hemodynamic, autonomic, and ventilatory responses to exercise in patients with chronic heart failure: Effects of physical training
    • Piepoli M, Clark AL, Volterrani M, Adamopoulos S, Sleight P, Coats AJ. Contribution of muscle afferents to the hemodynamic, autonomic, and ventilatory responses to exercise in patients with chronic heart failure: Effects of physical training. Circulation 1996;93:940-952.
    • (1996) Circulation , vol.93 , pp. 940-952
    • Piepoli, M.1    Clark, A.L.2    Volterrani, M.3    Adamopoulos, S.4    Sleight, P.5    Coats, A.J.6
  • 106
    • 0029007903 scopus 로고
    • Reversal of autonomic derangements by physical training in chronic heart failure assessed by heart rate variability
    • Kiilavuori K, Toivonen L, Naveri H, Leinonen H. Reversal of autonomic derangements by physical training in chronic heart failure assessed by heart rate variability. Eur Heart J 1995;16:490-495.
    • (1995) Eur Heart J , vol.16 , pp. 490-495
    • Kiilavuori, K.1    Toivonen, L.2    Naveri, H.3    Leinonen, H.4
  • 108
    • 0033537699 scopus 로고    scopus 로고
    • Randomized, controlled trial of long-term moderate exercise training in chronic heart failure: Effects on functional capacity, quality of life, and clinical outcome
    • Belardinelli R, Georgiou D, Cianci G, Purcaro A. Randomized, controlled trial of long-term moderate exercise training in chronic heart failure: Effects on functional capacity, quality of life, and clinical outcome. Circulation 1999;99:1173-1182.
    • (1999) Circulation , vol.99 , pp. 1173-1182
    • Belardinelli, R.1    Georgiou, D.2    Cianci, G.3    Purcaro, A.4
  • 109
    • 0028878919 scopus 로고
    • Constitutive NOS expression in cultured endothelial cells is elevated by fluid shear stress
    • Ranjan V, Xiao Z, Diamond SL. Constitutive NOS expression in cultured endothelial cells is elevated by fluid shear stress. Am J Physiol 1995;269:H550-H555.
    • (1995) Am J Physiol , vol.269
    • Ranjan, V.1    Xiao, Z.2    Diamond, S.L.3
  • 111
    • 0028118896 scopus 로고
    • Chronic exercise in dogs increases coronary vascular nitric oxide production and endothelial cell nitric oxide synthase gene expression
    • Sessa WC, Pritchard K, Seyedi N, Wang J, Hintze TH. Chronic exercise in dogs increases coronary vascular nitric oxide production and endothelial cell nitric oxide synthase gene expression. Circ Res 1994;74:349-353.
    • (1994) Circ Res , vol.74 , pp. 349-353
    • Sessa, W.C.1    Pritchard, K.2    Seyedi, N.3    Wang, J.4    Hintze, T.H.5
  • 112
    • 0027491127 scopus 로고
    • Chronic exercise enhances endothelium-mediated dilation of epicardial coronary artery in conscious dogs
    • Wang J, Wolin MS, Hintze TH. Chronic exercise enhances endothelium-mediated dilation of epicardial coronary artery in conscious dogs. Circ Res 1993;73:829-838.
    • (1993) Circ Res , vol.73 , pp. 829-838
    • Wang, J.1    Wolin, M.S.2    Hintze, T.H.3
  • 113
    • 33750744498 scopus 로고    scopus 로고
    • Induction of nitric oxide synthase mRNA in coronary resistance arteries isolated from exercise-trained pigs
    • Woodman CR, Muller JM, Laughlin MH, Price EM. Induction of nitric oxide synthase mRNA in coronary resistance arteries isolated from exercise-trained pigs. Am J Physiol 1997;273:H2575-H2579.
    • (1997) Am J Physiol , vol.273
    • Woodman, C.R.1    Muller, J.M.2    Laughlin, M.H.3    Price, E.M.4
  • 115
    • 0036479305 scopus 로고    scopus 로고
    • Shear stress stimulates phosphorylation of endothelial nitric-oxide synthase at Ser1179 by Akt-independent mechanisms: Role of protein kinase A
    • Boo YC, Sorescu G, Boyd N, Shiojima I, Walsh K, Du J, Jo H. Shear stress stimulates phosphorylation of endothelial nitric-oxide synthase at Ser1179 by Akt-independent mechanisms: Role of protein kinase A. J Biol Chem 2002;277:3388-3396.
    • (2002) J Biol Chem , vol.277 , pp. 3388-3396
    • Boo, Y.C.1    Sorescu, G.2    Boyd, N.3    Shiojima, I.4    Walsh, K.5    Du, J.6    Jo, H.7
  • 116
    • 0032567415 scopus 로고    scopus 로고
    • In situ flow activates endothelial nitric oxide synthase in luminal caveolae of endothelium with rapid caveolin dissociation and calmodulin association
    • Rizzo V, McIntosh DP, Oh P, Schnitzer JE. In situ flow activates endothelial nitric oxide synthase in luminal caveolae of endothelium with rapid caveolin dissociation and calmodulin association. J Biol Chem 1998;273:34724-34729.
    • (1998) J Biol Chem , vol.273 , pp. 34724-34729
    • Rizzo, V.1    McIntosh, D.P.2    Oh, P.3    Schnitzer, J.E.4
  • 117
    • 0033556208 scopus 로고    scopus 로고
    • Selective stimulation of L-arginine uptake contributes to shear stress-induced formation of nitric oxide
    • Posch K, Schmidt K, Graier WF. Selective stimulation of L-arginine uptake contributes to shear stress-induced formation of nitric oxide. Life Sci 1999;64:663-670.
    • (1999) Life Sci , vol.64 , pp. 663-670
    • Posch, K.1    Schmidt, K.2    Graier, W.F.3
  • 118
    • 0034201168 scopus 로고    scopus 로고
    • Regulation of the vascular extracellular superoxide dismutase by nitric oxide and exercise training
    • Fukai T, Siegfried MR, Ushio-Fukai M, Cheng Y, Kojda G, Harrison DG. Regulation of the vascular extracellular superoxide dismutase by nitric oxide and exercise training. J Clin Invest 2000;105:1631-1639.
    • (2000) J Clin Invest , vol.105 , pp. 1631-1639
    • Fukai, T.1    Siegfried, M.R.2    Ushio-Fukai, M.3    Cheng, Y.4    Kojda, G.5    Harrison, D.G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.