Effects of exercise training on left ventricular function and peripheral resistance in patients with chronic heart failure: A randomized trial

JAMA

Volumn 283, Issue 23, 2000, Pages 3095-3101

  Hambrecht, Rainer ^a   Gielen, Stephan ^a   Linke, Axel ^a   Fiehn, Eduard ^a   Yu, Jiangtao ^a   Walther, Claudia ^a   Schoene, Nina ^a   Schuler, Gerhard ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; EXERCISE; HEART FAILURE; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE OXYGEN CONSUMPTION; HEART RATE; HEART STROKE VOLUME; HEMODYNAMICS; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; VASCULAR RESISTANCE;

EID: 0034697756     PISSN: 00987484     EISSN: None     Source Type: Journal    
DOI: 10.1001/jama.283.23.3095     Document Type: Article

References (21)

1. Sullivan MJ, Higginbotham MB, Cobb FR. Exercise training in patients with severe left ventricular dysfunction: hemodynamic and metabolic effects. Circulation. 1988;78:506-515.
2. Coats AJS, Adamopoulos S, Meyer TE, Conway J, Sleight P. Effects of physical training in chronic heart failure. Lancet. 1990;335:63-66.
3. Hambrecht R, Niebauer J, Fiehn E, et al. Physical training in patients with stable chronic heart failure: effects on cardiorespiratory fitness and ultrastructural abnormalities of leg muscle. J Am Coll Cardiol. 1995;25:1239-1249.
4. Adamopoulos S, Coats AJS, Brunotte F, et al. Physical training improves skeletal muscle metabolism in patients with chronic heart failure. J Am Coll Cardiol. 1993;21:1101-1106.
5. Giannuzzi P, Temporelli P, Corrà U, Gattone M, Giordano P, Tavazzi L. Attenuation of unfavorable remodeling by exercise training in postinfarction patients with left ventricular dysfunction: results of the Exercise in Left Ventricular Dysfunction (ELVD) Trial. Circulation. 1997;96:1790-1797.
6. Dubach P, Myers J, Dziekan G, et al. Effect of exercise training on myocardial remodeling in patients with reduced left ventricular function after myocardial infarction. Circulation. 1997;95:2060-2067.
7. Wilson JR, Groves J, Rayos G. Circulatory status and response to cardiac rehabilitation in patients with heart failure. Circulation. 1996;94:1567-1572.
8. Demopoulos L, Bijou R, Fergus I, Jones M, Strom J, LeJemtel TH. Exercise training in patients with severe congestive heart failure: enhancing peak aerobic capacity while minimizing the increase in ventricular wall stress. J Am Coll Cardiol. 1997;29:597-603.
9. Hambrecht R, Fiehn E, Yu J, et al. Effects of endurance training on mitochondrial ultrastructure and fiber type distribution in skeletal muscle of patients with stable chronic heart failure. J Am Coll Cardiol. 1997; 29:1067-1073.
10. Hornig B, Maier V, Drexler H. Physical training improves endothelial function in patients with chronic heart failure. Circulation. 1996;93:210-214.
11. Katz SD, Yuen J, Bijou R, LeJemtel TH. Training improves endothelium-dependent vasodilation in resistance vessels of patients with heart failure. J Appl Physiol. 1997;82:1488-1492.
12. Hambrecht R, Fiehn E, Weigl C, et al. Regular physical exercise corrects endothelial dysfunction and improves exercise capacity in patients with chronic heart failure. Circulation. 1998;98:2709-2715.
13. Jugdutt BI, Michorowski BL, Kappagoda CT. Exercise training after anterior Q wave myocardial infarction: importance of regional left ventricular function and topography. J Am Coll Cardiol. 1988;12:362-372.
14. Weicker H. Bestimmung der freien und konjugierten Katecholamine mit HPLC unter amperometrischer Detektion. Lab Med. 1986;33:122-132.
15. Wassermann K, Whipp BJ, Koyal SH, Beaver WL. Anaerobic threshold and respiratory gas exchange during exercise. J Appl Physiol. 1973;35:236-243.
16. Schiller NB, Shah PM, Crawford M, for the American Society of Echocardiography Committee on Standards, Subcommittee on Quantitation of Two-Dimensional Echocardiography. Recommendations for quantitation of the left ventricle by two-dimensional echocardiography. J Am Soc Echocardiogr. 1989;2: 358-367.
17. Belardinelli R, Georgiou D, Cianci G, Berman N, Ginzton L, Purcaro A. Exercise training improves left ventricular diastolic filling in patients with dilated cardiomyopathy. Circulation. 1995;91:2775-2784.
18. Belardinelli R, Georgiou D, Cianci G, Purcaro A. Randomized, controlled trial of long-term moderate exercise training in chronic heart failure: effects on functional capacity, quality of life, and clinical outcome. Circulation. 1999;99:1173-1182.
19. Kubo SH, Rector TC, Williams RE, Heifritz SM, Bank AJ. Endothelium-dependent vasodilation is attenuated in patients with heart failure. Circulation. 1991; 84:1589-1596.
20. Katz SD, Krum H, Kahn T, Knecht M. Exercise-induced vasodilation in forearm circulation of normal subjects and patients with congestive heart failure: role of endothelium-derived nitric oxide. J Am Coll Cardiol. 1996;28:585-590.
21. Coats AJS, Adamopoulos S, Radaelli A, et al. Controlled trial of physical training in chronic heart failure: exercise performance, hemodynamics, ventilation, and autonomic function. Circulation. 1992;85: 2119-2131.