Simple centromere, complex kinetochore: Linking spindle microtubules and centromeric DNA in budding yeast

Journal of Cell Biology

Volumn 157, Issue 2, 2002, Pages 199-203

  Cheeseman, Iain M ^a   Drubin, David G ^a   Barnes, Georjana ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA BINDING PROTEIN; MICROTUBULE ASSOCIATED PROTEIN;

CENTROMERE; DNA SEQUENCE; MICROTUBULE; MITOSIS SPINDLE; MODEL; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SHORT SURVEY;

DNA, FUNGAL; DNA-BINDING PROTEINS; KINETOCHORES; MITOTIC SPINDLE APPARATUS; MODELS, BIOLOGICAL; SACCHAROMYCES CEREVISIAE PROTEINS; SACCHAROMYCETALES;

EUKARYOTA; FUNGI; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCETALES;

EID: 0037092041     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200201052     Document Type: Short Survey

References (45)

1. The spindle checkpoint
2. The budding yeast protein kinase Ipl1/Aurora allows the absence of tension to activate the spindle checkpoint
3. The conserved protein kinase Ipl1 regulates microtubule binding to kinetochores in budding yeast
4. Implication of a novel multiprotein Dam1p complex in outer kinetochore function
5. Mitotic spindle integrity and kinetochore function linked by the Duo1p/Dam1p complex
6. Dad1p, third component of the Duo1p/Dam1p complex involved in kinetochore function and mitotic spindle integrity
7. Probing the architecture of a simple kinetochore using DNA-protein crosslinking
8. Nucleotide sequence comparisons and functional analysis of yeast centromere DNAs
9. The spindle checkpoint of the yeast Saccharomyces cerevisiae requires kinetochore function and maps to the CBF3 domain
10. The IML3/MCM19 gene of Saccharomyces cerevisiae is required for a kinetochore-related process during chromosome segregation
11. NDC10: A gene involved in chromosome segregation in Saccharomyces cerevisiae
12. Establishing biorientation occurs with precocious separation of the sister kinetochores, but not the arms, in the early spindle of budding yeast
13. Transient sister chromatid separation and elastic deformation of chromosomes during mitosis in budding yeast
14. Molecular analysis of kinetochore-microtubule attachment in budding yeast
15. Motor function in the mitotic spindle
16. The budding yeast proteins Spc24p and Spc25p interact with Ndc80p and Nuf2p at the kinetochore and are important for kinetochore clustering and checkpoint control
17. Four new sub-units of the Dam1-Duo1 complex reveal novel functions in sister kinetochore biorientation
18. Centromere clustering is a major determinant of yeast interphase nuclear organization
19. Yeast Dam1p has a role at the kinetochore in assembly of the mitotic spindle
20. Functional cooperation of Dam1, Ipl1, and the inner centromere protein (INCENP)-related protein Sli15 during chromosome segregation
21. Sli15 associates with the ipl1 protein kinase to promote proper chromosome segregation in Saccharomyces cerevisiae
22. A 240 kd multisubunit protein complex, CBF3, is a major component of the budding yeast centromere
23. The mitotic spindle is required for loading of the DASH complex onto the kinetochore
24. Polyploids require Bik1 for kinetochore-microtubule attachment
25. Ctf3p, the Mis6 budding yeast homolog, interacts with Mcm22p and Mcm16p at the yeast outer kinetochore
26. CPF1, a yeast protein which functions in centromeres and promoters
27. Evidence that the MIF2 gene of Saccharomyces cerevisiae encodes a centromere protein with homology to the mammalian centromere protein CENP-C
28. Budding yeast centromere composition and assembly as revealed by in vivo cross-linking
29. Cse4p is a component of the core centromere of Saccharomyces cerevisiae
30. KAR3-encoded kinesin is a minus-end-directed motor that functions with centromere binding proteins (CBF3) on an in vitro yeast kinetochore
31. The kinesin-related proteins, Kip2p and Kip3p, function differently in nuclear migration in yeast
32. M phase-specific kinetochore proteins in fission yeast: Microtubule-associating Dis1 and Mtc1 display rapid separation and segregation during anaphase
33. Cpf1 protein induced bending of yeast centromere DNA element 1
34. A putative protein complex consisting of Ctf19, Mcm21, and Okp1 represents a missing link in the budding yeast kinetochore
35. The mcm17 mutation of yeast shows a size-dependent segregational defect of a mini-chromosome
36. Stu2 promotes mitotic spindle elongation in anaphase
37. Factors required for the binding of reassembled yeast kinetochores to microtubules in vitro
38. Lack of tension at kinetochores activates the spindle checkpoint in budding yeast
39. Evidence that the Ipl1-Sli15 (aurora kinase-INCENP) complex promotes chromosome bi-orientation by altering kinetochore-spindle pole connections
40. Crystal structure of the CENP-B protein-DNA complex: The DNA-binding domains of CENP-B induce kinks in the CENP-B box DNA
41. Systematic genetic analysis with ordered arrays of yeast deletion mutants
42. The Ndc80p complex from Saccharomyces cerevisiae contains conserved centromere components and has a function in chromosome segregation
43. Participation of Bir1p, a member of the inhibitor of apoptosis family, in yeast chromosome segregation events
44. Slk19p is a centromere protein that functions to stabilize mitotic spindles