Voltage-dependent blockade of connexin40 gap junctions by spermine

Biophysical Journal

Volumn 84, Issue 1, 2003, Pages 205-219

  Musa, Hassan ^a   Veenstra, Richard D ^a  

^a State University of New York Upstate Medical University: College of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMMONIUM DERIVATIVE; CONNEXIN 40; CONNEXIN 43; ION CHANNEL; POLYAMINE; SPERMIDINE; SPERMINE;

ANIMAL CELL; ARTICLE; CELL LEVEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISSOCIATION CONSTANT; DRUG EFFECT; DRUG SELECTIVITY; ELECTRIC POTENTIAL; GAP JUNCTION; ION CONDUCTANCE; NONHUMAN; PROTEIN EXPRESSION; RAT;

ANIMALIA;

EID: 0037214677     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(03)74843-7     Document Type: Article

References (59)

1. + channel Kir2.1. J. Physiol. (Lond.). 493:643-649.
2. + channels. Effects of channel gating, voltage, and ionic strength. J. Gen. Physiol. 91:317-333.
3. Armstrong, C. M. 1971. Interaction of tetraethylammonium ion derivatives with the potassium channels of giant axons. J. Gen. Physiol. 58:413-437.
4. 3. J. Gen. Physiol. 109:509-522.
5. Beblo, D. A., H.-Z. Wang, E. C. Beyer, E. M. Westphale, and R. D. Veenstra. 1995. Unique conductance, gating, and selective permeability properties of gap junction channels formed by connexin40. Circ. Res. 77:813-822.
6. Bergeron, R. J., J. Wiegand, W. R. Weimar, and P. S. Snyder. 1998. Polyamine analogue antiarrythmics. Pharm. Res. 38:367-380.
7. Beyer, E. C., D. L. Paul, and D. A. Goodenough. 1990. Connexin family of gap junction proteins. J. Membr. Biol. 116:187-194.
8. Beyer, E. C., and K. Willecke. 2000. Gap junction genes and their regulation. In Gap Junctions, Advances in Molecular and Cell Biology, Vol. 30. E. L. Hertzberg, editor. JAI Press, Stamford. 1-30.
9. Dani, J. A. 1986. Ion-channel entrances influence permeation. Biophys. J. 49:607-618.
10. Dobrovinskaya, O. R., J. Muñiz, and I. I. Pottosin. 1999, Inhibition of vacuolar ion channels by polyamines. J. Membrane Biol. 167:127-140.
11. Donevan, S. D., and M. A. Ragowski. 1996. Multiple actions of arylalkylmine arthropod toxins on the N-methyl-D-asparate receptor. Neuroscience. 70:361-375.
12. Elfgang, C., R. Eckert, H. Lichtenberg-Frate, A. Butterweck, O. Traub, R. A. Klein, D. Hülser, and K. Willecke. 1995. Specific permeability and selective formation of gap junction channels in connexin-transfected HeLa cells. J. Cell Biol. 129:805-817.
13. French, R. J., and J. J. Shoukimas. 1985. An ion's view of the potassium channel. The structure of the permeation pathway as sensed by a variety of blocking ions. J. Gen. Physiol. 85:669-698.
14. Ficker, E., M. Taglialatela, B. A. Wible, C. M. Henley, and A. M. Brown. 1994. Spermine and spermidine as gating molecules for inward rectifier K+ channels. Science. 266:1068-1072.
15. Green, W. N., and O. S. Anderson. 1991. Surface charge and ion channel function. Annu. Rev. Physiol. 53:341-359.
16. Green, W. N., L. B. Weiss, and O. S. Anderson. 1987. Batrachotoxin-modified sodium channels in planar lipid bilayers. Ion permeation and block. J. Gen. Physiol. 89:841-872.
17. Goodenough, D. A., J. A. Goliger, and D. L. Paul. 1996. Connexins, connexons and intracellular communication. Annu. Rev. Biochem. 65:475-502.
18. Guo, D., and Z. Lu. 2000a. Mechanism of cGMP-gated channel block by intracellular polyamines. J. Gen. Physiol. 115:783-797.
19. Guo, D., and Z. Lu. 2000b. Mechanism of IRK1 channel block by intracellular polyamines. J. Gen. Physiol. 115:799-813.
20. Haghighi, A. P., and E. Cooper. 1998. Neuronal nicotinic acetylcholine receptors are blocked by intracellular spermine in a voltage dependent manner. J. Neurosci. 18:4050-4062.
21. Harris, A. L., D. C. Spray, and M. V. L. Bennett. 1981. Kinetic properties of a voltage-dependent junctional conductance. J. Gen. Physiol. 77:95-117.
22. Hoshi, T., W. N. Zagotta, and R. W. Aldrich. 1990. Biophysical and molecular mechanisms of Shaker potassium channel inactivation. Science. 250:533-538.
23. Hurst, R. S., R. Latorre, L. Toro, and E. Stefani. 1995. External barium block of Shaker potassium channels: Evidence for two binding sites. J. Gen. Physiol. 106:1069-1087.
24. Imanaga, I., M. Kameyama, and H. Irisawa. 1987. Cell-to-cell diffusion of fluorescent dyes in paired ventricular myocytes. Am. J. Physiol. 252:H223-H232.
25. Imoto, K., C. Busch, B. Sakmann, M. Mishina, T. Konno, J. Nakai, H. Bujo, Y. Mori, K. Fukuda, and S. Numa. 1988. Rings of negatively charged amino acids determine the acetylcholine receptor conductance. Nature. 335:645-648.
26. + channel. Nature. 353:86-90.
27. Lee, J.-K., S. A. John, and J. N. Weiss. 1999. Novel gating mechanism of polyamine block in the strong inward rectifier K channel Kir2.1. J. Gen. Physiol. 113:555-563.
28. Lopatin, A. N., E. N. Makhina, and C. G. Nichols. 1994. Potassium channel block by cytoplasmic polyamines as the mechanism of intrinsic rectification, Nature. 372:366-369.
29. Lopatin, A. N., E. N. Makhina, and C. G. Nichols. 1995. The mechanism of inward rectification of potassium channels: "Long-pore plugging" by cytoplasmic polyamines. J. Gen. Physiol. 106:923-955.
30. Lopatin, A. N., L. M. Shantz, C. A. Macintosh, C. G. Nichols, and A. E. Pegg. 2000. Modulation of potassium channels in the hearts of transgenic and mutant mice with altered polyamine biosynthesis. J. Mol. Cell. Cardiol. 32:2007-2024.
31. Lu, Z., and L. Ding. 1999. Blockade of a retinal cGMP-gated channel by polyamines. J. Gen. Physiol. 113:35-43.
32. + channels. Science. 250:276-279.
33. Makowski, L., D. L. D. Casper, W. C. Phillips, and D. A. Goodenough. 1977. Gap junction structure II. Analysis of the x-ray diffraction data. J. Cell Biol. 74:629-645.
34. Manivannan, K., S. V. Ramanan, R. T. Mathias, and P. R. Brink. 1992. Multichannel recordings from membranes which contain gap junctions. Biophys. J. 61:216-227.
35. Musa, H., J. D. Gough, W. J. Lees, and R. D. Veenstra. 2001. Ionic blockade of the rat connexin40 gap junction channel by large tetraalkylammonium ions. Biophys. J. 81:3253-3274.
36. Nichols, C. G., E. N. Makhina, W. L. Pearson, Q. Sha, and A. N. Lopatin. 1996. Inward rectification and implications for cardiac excitability. Circ. Res. 78:1-7.
37. Oh, S., C. K. Abrams, V. K. Verselis, and T. A. Bargiello. 2000. Stoichiometry of transjunctional votlage-gating polarity reversal by a negative charge substitution in the amino terminus of a connexin32 chimera. J. Gen. Physiol. 116:13-31.
38. Perkins, G., D. Goodenough, and G. Sosinsky. 1997. Three-dimensional structure of the gap junction connexon. Biophys. J. 72:533-544.
39. Rock, D. M., and R. L. Macdonald. 1992. Spermine and related polyamines produce a voltage dependent reduction of N-methyl-D-aspartate receptor single-channel conductance. Mol. Pharmacol. 42:157-164.
40. + channels. Pflügers Arch. 441:1-11.
41. Scott, R. H., K. G. Sutton, and A. C. Dolphin. 1993. Interactions of polyamines with neuronal ion channels. Trends Neurosci. 16:153-160.
42. Shore, L., P. McLean, S. K. Gilmour, M. B. Hodgins, and M. E. Finbow. 2001. Polyamines regulate gap junction communication in connexin 43-expressing cells. Biochem. J. 357:489-495.
43. Spray, D. C., A. L. Harris, and M. V. L. Bennett. 1981. Equilibrium properties of a voltage dependent junctional conductance. J. Gen. Physiol. 77:77-93.
44. Trexler, E. B., M. V. L. Bennett, T. A. Bargiello, and V. K. Verselis. 1996. Voltage gating and permeation in a gap junction hemichannel. Proc. Natl. Acad. Sci. USA. 93:5836-5841.
45. Trexler, E. B., F. F. Bukauskas, J. Kronengold, T. A. Bargiello, and V. K. Verselis. 2000. Voltage gating and permeation in a gap junction hemichannel. Biophys. J. 79:3036-3051.
46. Unger, V. M., N. M. Kumar, N. B. Gilula, and M. Yeager. 1999. Three-dimensional structure of a recombinant gap junction membrane channel. Science. 283:1176-1180.
47. Valiunas, V., R. Weingart, and P. R. Brink. 2000. Formation of heterotypic gap junction channels by connexins 40 and 43. Circ. Res. 86:e42-e49.
48. Veenstra, R. D. 2000. Ion permeation through connexin gap junction channels: Effects on conductance and selectivity. In Gap Junctions, Molecular Basis of Cell Communication in Health and Disease, Current Topics in Membranes, Vol. 49. C. Peracchia, editor. Academic Press, San Diego. 95-129.
49. Veenstra, R. D. 2001. Voltage clamp limitations of dual whole-cell gap junction current and voltage recordings. I. Conductance measurements. Biophys. J. 80:2231-2247.
50. Veenstra, R. D., H.-Z. Wang, D. A. Beblo, M. G. Chilton, A. L. Harris, E. C. Beyer, and P. R. Brink. 1995. Selectivity of connexin-specific gap junctions does not correlate with channel conductance. Circ. Res. 77:1156-1165.
51. Verselis, V., C. S. Ginter, and T. A. Bargiello. 1994. Opposite voltage gating polarities of two closely related connexins. Nature. 368:348-351.
52. Wang, H.-Z., J. Li, L. F. Lemanski, and R. D. Veenstra. 1992. Gating of mammalian gap junction channels by transjunctional voltage. Biophys. J. 63:139-151.
53. Wang, H.-Z., and R. D. Veenstra. 1997. Monovalent ion selectivity sequences of the rat connexin43 gap junction channel. J. Gen. Physiol. 109:491-507.
54. + channels localized to a single negatively charged residue. Nature. 371:246-249.
55. Williams, K. 1997. Interactions of polyamines with ion channels. Biochem. J. 325:289-297.
56. Woodhull, A. M. 1973. Ionic blockage of sodium channels in nerve. J. Gen. Physiol. 61:687-708.
57. + channel. Neuron. 14:1047-1054.
58. Yellen, G. 1987. Permeation in potassium channels: Implications for channel structure. Annu. Rev. Biophys. Biophys. Chem. 16:227-246.
59. Zhou, X.-W., A. Pfahnl, R. Werner, A. Hudder, A. Llanes, A. Luebke, and G. Dahl. 1997. Identification of a pore lining segment in gap junction hemichannels. Biophys. J. 72:1946-1953.