Mechanism of IRK1 channel block by intracellular polyamines

Journal of General Physiology

Volumn 115, Issue 6, 2000, Pages 799-813

  Gou, Donglin ^a   Lu, Zhe ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Diamine; Inward rectifier K+ channel; Ion permeation; Polyamine; Protonation

Indexed keywords

DIAMINE DERIVATIVE; POLYAMINE; POTASSIUM CHANNEL; POTASSIUM ION; PUTRESCINE; SPERMIDINE; SPERMINE DERIVATIVE; TETRYLAMMONIUM;

ANIMAL CELL; ARTICLE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; NONHUMAN; OOCYTE; POTASSIUM CURRENT; XENOPUS LAEVIS;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; HYDROGEN-ION CONCENTRATION; ION CHANNEL GATING; KINETICS; MEMBRANE POTENTIALS; MODELS, MOLECULAR; OOCYTES; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PUTRESCINE; SPERMINE; TETRAETHYLAMMONIUM; XENOPUS LAEVIS;

EID: 0343798541     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.115.6.799     Document Type: Article

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