Ionic blockade of the rat connexin40 gap junction channel by large tetraalkylammonium ions

Biophysical Journal

Volumn 81, Issue 6, 2001, Pages 3253-3274

  Musa, Hassan ^a   Gough, Jonathan D ^b   Lees, Watson J ^b   Veenstra, Richard D ^a,c  

^a State University of New York Upstate Medical University: College of Medicine   (United States)

^b SYRACUSE UNIVERSITY   (United States)

^c SUNY UPSTATE MEDICAL UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMMONIA; CONNEXIN 40; N OCTYL TRIBUTYLAMMONIUM; N OCTYL TRIETHYLAMMONIUM; POTASSIUM; POTASSIUM CHLORIDE; TETRABUTYLAMMONIUM; TETRAHEXYLAMMONIUM; TETRAMETHYLAMMONIUM; TETRAPENTYLAMMONIUM; TETRYLAMMONIUM; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHEMICAL COMPOSITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISSOCIATION CONSTANT; ELECTRIC POTENTIAL; GAP JUNCTION; HYDROPHOBICITY; INCUBATION TIME; ION PERMEABILITY; ION TRANSPORT; MICHAELIS CONSTANT; NONHUMAN; RAT; STEREOSPECIFICITY; TRANSPORT KINETICS;

ANIMALIA;

EID: 0035193297     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(01)75960-7     Document Type: Article

References (47)

1. + channels. Effects of channel gating, voltage, and ionic strength
2. The carboxyl terminal domain regulates the unitary conductance and voltage dependence of connexin40 gap junction channels
3. Interaction of tetraethylammonium ion derivatives with the potassium channels of giant axons
4. Anomalous rectification in squid giant axon with tetraethylammonium chloride
5. Cardiac gap junction configuration after an uncoupling treatment as a function of time
6. Heptanol-induced decrease in cardiac gap junction conductance is mediated by a decrease in the fluidity of membraneous cholesterol-rich domains
7. 3
8. Unique conductance, gating, and selective permeability properties of gap junction channels formed by connexin40
9. Voltage-dependent block of anthrax toxin channels in planar phospholipid bilayer membranes by symmetric tetraalkylammonium ions. Effects on macroscopic conductance
10. Diffusion limitation in the block by symmetric tetraalkylammonium ions of anthrax toxin channels in planar phospholipid bilayer membranes
11. Voltage-dependent block of anthrax toxin channels in planar phospholipid bilayer membranes by symmetric tetraalkylammonium ions. Single-channel analysis
12. Uncoupling of cardiac cells by doxyl stearic acids: Specificity and mechanism of action
13. Volatile anesthetics block intercellular communication between neonatal rat myocardial cells
14. The internal quaternary ammonium receptor site of Shaker potassium channels
15. Glycyrrhetinic acid derivatives: A novel class of inhibitors of gap-junctional intercellular communication. Structure-activity relationships
16. An ion's view of the potassium channel. The structure of the permeation pathway as sensed by a variety of blocking ions
17. The sleep-inducing lipid oleamide deconvolutes gap junction communication and calcium wave transmission in glial cells
18. Hydroxide ion initiated reactions under phase transfer catalysis conditions - IV. Effect of catalyst structure
19. + channel
20. External barium block of Shaker potassium channels: Evidence for two binding sites
21. Interaction of anaesthetics with electrical synapses
22. Spring constants for channel-induced lipid bilayer deformations. Estimates using gramicidin channels
23. + channel
24. + channels
25. Multichannel recordings from membranes which contain gap junctions
26. Repulsion between tetraethylammonium ions in cloned voltage-gated potassium channels
27. Gap junctions. Structural changes after uncoupling procedures
28. Three-dimensional structure of the gap junction connexon
29. Block of neuronal chloride channels by tetraethylammonium ion derivatives
30. Slow permeation of organic cations in acetylcholine receptor channels
31. Structure-activity relations of the cardiac gap junction channel
32. Mechanism of heptanol-induced uncoupling of cardiac gap junctions: A perforated patch-clamp study
33. 2+-release channel
34. Voltage gating and permeation in a gap junction hemichannel
35. Three-dimensional structure of a recombinant gap junction membrane channel
36. Ion permeation through connexin gap junction channels: Effects on conductance and selectivity
37. Voltage clamp limitations of dual whole-cell gap junction current and voltage recordings. I. Conductance measurements
38. Regulation of single channel activity in cardiac gap junctions
39. Patch clamp analysis of gap junctional currents
40. Biophysics of gap junction channels
41. Monovalent ion selectivity sequences of the rat connexin43 gap junction channel
42. Ionic blockage of sodium channels in nerve
43. Inhibition of gap junctional conductance by long-chain acylcarnitines and their preferential accumulation in junctional sarcolemma during hypoxia
44. Permeation in potassium channels: Implications for channel structure
45. The ion selectivity of a membrane conductance inactivated by extracellular calcium in Xenopus oocytes