Crystal structure of dengue virus NS3 protease in complex with a bowman-birk inhibitor: Implications for flaviviral polyprotein processing and drug design

Journal of Molecular Biology

Volumn 301, Issue 4, 2000, Pages 759-767

  Krishna Murthy, H M ^a   Judge, K ^a   DeLucas, L ^a   Padmanabhan, R ^b  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

Author keywords

Bowman Birk inhibitor; Conformational change; Dengue virus; Drug design; Substrate recognition

Indexed keywords

ANTINEOPLASTIC AGENT; BOWMAN BIRK INHIBITOR; PROTEINASE INHIBITOR; SERINE PROTEINASE; VIRUS ENZYME; VIRUS PROTEIN;

ARTICLE; CATALYSIS; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DENGUE VIRUS; DRUG DESIGN; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; VIRION;

DENGUE VIRUS; DENGUE VIRUS GROUP; FLAVIVIRIDAE;

EID: 0034714111     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2000.3924     Document Type: Article

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