메뉴 건너뛰기




Volumn 951, Issue 1, 2002, Pages 96-106

Differential effects of phospholipase inhibitors on free fatty acid efflux in rat cerebral cortex during ischemia-reperfusion injury

Author keywords

Cerebral ischemia; Free fatty acids; Phospholipases; PLA2; PLC

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 3 (3 ACETAMIDE 1 BENZYL 2 ETHYLINDOLYL 5 OXY)PROPANE SULFONIC ACID; 4 BROMOPHENYLACYL BROMIDE; ARACHIDONIC ACID; ARACHIDONYL TRIFLUOROMETHYL KETONE; BROMOENOL LACTONE; DOCOSAHEXAENOIC ACID; FATTY ACID; LINOLEIC ACID; LY 311727; MYRISTIC ACID; OLEIC ACID; PALMITIC ACID; PHOSPHOLIPASE A2 INHIBITOR; PHOSPHOLIPASE C INHIBITOR; SULFONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

EID: 0037183749     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(02)03142-6     Document Type: Article
Times cited : (28)

References (72)
  • 5
    • 0029862974 scopus 로고    scopus 로고
    • 2 enzymes present in P388D1 macrophages
    • 2 enzymes present in P388D1 macrophages. J. Biol. Chem. 271:1996;6758-6765.
    • (1996) J. Biol. Chem. , vol.271 , pp. 6758-6765
    • Balsinde, J.1    Dennis, E.A.2
  • 7
    • 0016904705 scopus 로고
    • Free arachidonic acid and other lipids in the nervous system during early ischemia and after electroshock
    • Bazan N.G. Free arachidonic acid and other lipids in the nervous system during early ischemia and after electroshock. Adv. Exp. Med. Biol. 72:1976;317-335.
    • (1976) Adv. Exp. Med. Biol , vol.72 , pp. 317-335
    • Bazan, N.G.1
  • 8
    • 0014935332 scopus 로고
    • Effects of ischemia and electroconvulsive shock on free fatty acid pool in the brain
    • Bazan N.G. Effects of ischemia and electroconvulsive shock on free fatty acid pool in the brain. Biochim. Biophys. Acta. 218:1970;1-10.
    • (1970) Biochim. Biophys. Acta , vol.218 , pp. 1-10
    • Bazan, N.G.1
  • 10
    • 0027987896 scopus 로고
    • Myristate exchange. A second glycosyl phosphatidylinositol myristoylation reaction in African trypanosomes
    • Buxbaum L.U., Raper J., Opperdoes F.R., Englund P.T. Myristate exchange. A second glycosyl phosphatidylinositol myristoylation reaction in African trypanosomes. J. Biol. Chem. 269:1994;30212-30220.
    • (1994) J. Biol. Chem. , vol.269 , pp. 30212-30220
    • Buxbaum, L.U.1    Raper, J.2    Opperdoes, F.R.3    Englund, P.T.4
  • 13
    • 0018168536 scopus 로고
    • Brain edema: Induction in cortical slices by polyunsaturated fatty acids
    • Chan P.H., Fishman R.A. Brain edema: induction in cortical slices by polyunsaturated fatty acids. Science. 201:1978;358-360.
    • (1978) Science , vol.201 , pp. 358-360
    • Chan, P.H.1    Fishman, R.A.2
  • 14
    • 0033557742 scopus 로고    scopus 로고
    • Early metabolic inhibition-induced intracellular sodium and calcium increase in rat cerebellar granule cells
    • Chen W.H., Chu K.C., Wu S.J., Wu J.C., Shui H.A., Wu M.L. Early metabolic inhibition-induced intracellular sodium and calcium increase in rat cerebellar granule cells. J. Physiol. 15:1999;133-146.
    • (1999) J. Physiol. , vol.15 , pp. 133-146
    • Chen, W.H.1    Chu, K.C.2    Wu, S.J.3    Wu, J.C.4    Shui, H.A.5    Wu, M.L.6
  • 15
    • 0025016922 scopus 로고
    • 2+ pool in T cells through a mechanism independent of phosphoinositide turnover
    • 2+ pool in T cells through a mechanism independent of phosphoinositide turnover. J. Biol. Chem. 15:1990;902-907.
    • (1990) J. Biol. Chem. , vol.15 , pp. 902-907
    • Chow, S.C.1    Jondal, M.2
  • 18
    • 0030614354 scopus 로고    scopus 로고
    • 2 superfamily of signal transduction enzymes
    • 2 superfamily of signal transduction enzymes. Trends Biochem. Sci. 22:1997;1-2.
    • (1997) Trends Biochem. Sci. , vol.22 , pp. 1-2
    • Dennis, E.A.1
  • 19
    • 0032990141 scopus 로고    scopus 로고
    • Severity of experimental brain injury on lactate and free fatty acid accumulation and Evans blue extravasation in the rat cortex and hippocampus
    • Dhillon H.S., Carman H.M., Zhang D., Scheff S.W., Prasad M.R. Severity of experimental brain injury on lactate and free fatty acid accumulation and Evans blue extravasation in the rat cortex and hippocampus. J. Neurotrauma. 16:1999;455-469.
    • (1999) J. Neurotrauma , vol.16 , pp. 455-469
    • Dhillon, H.S.1    Carman, H.M.2    Zhang, D.3    Scheff, S.W.4    Prasad, M.R.5
  • 20
    • 0031193507 scopus 로고    scopus 로고
    • Time course of changes in lactate and free fatty acids after experimental brain injury and relationship to morphologic damage
    • Dhillon H.S., Dose J.M., Scheff S.W., Prasad M.R. Time course of changes in lactate and free fatty acids after experimental brain injury and relationship to morphologic damage. Exp. Neurol. 146:1997;240-249.
    • (1997) Exp. Neurol. , vol.146 , pp. 240-249
    • Dhillon, H.S.1    Dose, J.M.2    Scheff, S.W.3    Prasad, M.R.4
  • 21
    • 0030615284 scopus 로고    scopus 로고
    • 2 inhibitor, quinacrine, reduces infarct size in rats after transient middle cerebral artery occlusion
    • 2 inhibitor, quinacrine, reduces infarct size in rats after transient middle cerebral artery occlusion. Brain Res. 752:1997;203-208.
    • (1997) Brain Res. , vol.752 , pp. 203-208
    • Estevez, A.Y.1    Phillis, J.W.2
  • 22
    • 0033062508 scopus 로고    scopus 로고
    • 2 activity: Their neurochemical effects and therapeutical importance for neurological disorders
    • 2 activity: Their neurochemical effects and therapeutical importance for neurological disorders. Brain Res Bull. 49:1999;139-153.
    • (1999) Brain Res Bull. , vol.49 , pp. 139-153
    • Farooqui, A.A.1    Litsky, M.L.2    Farooqui, T.3    Horrocks, L.A.4
  • 24
  • 25
    • 0032528154 scopus 로고    scopus 로고
    • Cyclosporin A, but not FK506, protects mitochondria and neurons against hypoglycemic damage and implicates the mitochondrial permeability transition in cell death
    • Friberg H., Ferrand Drake M., Bengtsson F., Halestrap A.P., Wieloch T. Cyclosporin A, but not FK506, protects mitochondria and neurons against hypoglycemic damage and implicates the mitochondrial permeability transition in cell death. J. Neurosci. 18:1998;5151-5159.
    • (1998) J. Neurosci. , vol.18 , pp. 5151-5159
    • Friberg, H.1    Ferrand Drake, M.2    Bengtsson, F.3    Halestrap, A.P.4    Wieloch, T.5
  • 27
    • 0025758304 scopus 로고
    • "Ex vivo" release of eicosanoid from human brain tissue: Its relevance in the development of brain edema
    • Gaetani P., Rodriguez y Baena R., Marzatico F., Lombardi D., Knerich R., Paoletti P. "Ex vivo" release of eicosanoid from human brain tissue: its relevance in the development of brain edema. Neurosurgery. 28:1991;853-857.
    • (1991) Neurosurgery , vol.28 , pp. 853-857
    • Gaetani, P.1    Rodriguez y Baena, R.2    Marzatico, F.3    Lombardi, D.4    Knerich, R.5    Paoletti, P.6
  • 28
    • 0000320637 scopus 로고
    • Free fatty acids in the brain in moderate and severe hypoxia
    • Gardiner M., Nilsson B., Rehncrona S., Siesjo B.K. Free fatty acids in the brain in moderate and severe hypoxia. J. Neurochem. 52:1981;946-951.
    • (1981) J. Neurochem. , vol.52 , pp. 946-951
    • Gardiner, M.1    Nilsson, B.2    Rehncrona, S.3    Siesjo, B.K.4
  • 29
    • 0031593893 scopus 로고    scopus 로고
    • 2 inhibitor, inhibits arachidonate incorporation and turnover in brain phospholipids of the awake rat
    • 2 inhibitor, inhibits arachidonate incorporation and turnover in brain phospholipids of the awake rat. Neurochem. Res. 22:1998;1251-1257.
    • (1998) Neurochem. Res. , vol.22 , pp. 1251-1257
    • Grange, E.1    Rabin, O.2    Bell, J.3    Chang, M.C.J.4
  • 30
    • 0017127859 scopus 로고
    • Hamster brain adipose tissue mitochondria. The role of fatty acids and proton conductance of the inner membrane
    • Heaton G.M., Nicholls D.G. Hamster brain adipose tissue mitochondria. The role of fatty acids and proton conductance of the inner membrane. J. Biochem. 67:1976;511-517.
    • (1976) J. Biochem. , vol.67 , pp. 511-517
    • Heaton, G.M.1    Nicholls, D.G.2
  • 31
    • 0034075646 scopus 로고    scopus 로고
    • Cortical impact injury in rats promotes a rapid and sustained increase in polyunsaturated free fatty acids and diacylglycerols
    • Homayoun P., Parkins N.E., Soblosky J., Carey M.E., Rodriguez de Turco E.B., Bazan N.G. Cortical impact injury in rats promotes a rapid and sustained increase in polyunsaturated free fatty acids and diacylglycerols. Neurochem. Res. 25:2000;269-276.
    • (2000) Neurochem. Res. , vol.25 , pp. 269-276
    • Homayoun, P.1    Parkins, N.E.2    Soblosky, J.3    Carey, M.E.4    Rodriguez de Turco, E.B.5    Bazan, N.G.6
  • 33
    • 0031985644 scopus 로고    scopus 로고
    • Mild hypothermia reduces the rate of metabolism of arachidonic acid following postischemic reperfusion
    • Kubota M., Nakane M., Narita K., Nakagomi T., Tamura A., Hisaki H., Shimasaki H., Ueta N. Mild hypothermia reduces the rate of metabolism of arachidonic acid following postischemic reperfusion. Brain Res. 779:1998;297-300.
    • (1998) Brain Res. , vol.779 , pp. 297-300
    • Kubota, M.1    Nakane, M.2    Narita, K.3    Nakagomi, T.4    Tamura, A.5    Hisaki, H.6    Shimasaki, H.7    Ueta, N.8
  • 34
    • 0028238064 scopus 로고
    • 2 in rat brain after severe forebrain ischemia and in endotoxic shock
    • 2 in rat brain after severe forebrain ischemia and in endotoxic shock. Brain Res. 651:1994;353-356.
    • (1994) Brain Res. , vol.651 , pp. 353-356
    • Lauritzen, I.1    Heurteaux, C.2    Lazdunski, M.3
  • 37
    • 0032007328 scopus 로고    scopus 로고
    • Modification of ion homeostasis by lipid peroxidation: Roles in neuronal degeneration and adaptive plasticity
    • Mattson M.P. Modification of ion homeostasis by lipid peroxidation: roles in neuronal degeneration and adaptive plasticity. Trends Neurosci. 21:1998;53-57.
    • (1998) Trends Neurosci. , vol.21 , pp. 53-57
    • Mattson, M.P.1
  • 39
    • 0028861597 scopus 로고
    • A possible role for phospholipases in the release of neurotransmitter amino acids from ischemic rat cerebral cortex
    • O'Regan M.H., Smith-Barbour M., Perkins L.M., Phillis J.W. A possible role for phospholipases in the release of neurotransmitter amino acids from ischemic rat cerebral cortex. Neurosci. Lett. 185:1995;191-194.
    • (1995) Neurosci. Lett. , vol.185 , pp. 191-194
    • O'Regan, M.H.1    Smith-Barbour, M.2    Perkins, L.M.3    Phillis, J.W.4
  • 41
    • 0024411914 scopus 로고
    • Arachidonic acid and other fatty acids directly activate potassium channels in smooth muscle cells
    • Ordway R.W., Walsh J.W., Singer J.J. Arachidonic acid and other fatty acids directly activate potassium channels in smooth muscle cells. Science. 244:1989;1176-1179.
    • (1989) Science , vol.244 , pp. 1176-1179
    • Ordway, R.W.1    Walsh, J.W.2    Singer, J.J.3
  • 42
    • 0032703776 scopus 로고    scopus 로고
    • Mellitin enhances amino acid and free fatty acid release from the in vivo cerebral cortex
    • Phillis J.W., Song D., O'Regan M.H. Mellitin enhances amino acid and free fatty acid release from the in vivo cerebral cortex. Brain Res. 847:1999;270-275.
    • (1999) Brain Res , vol.847 , pp. 270-275
    • Phillis, J.W.1    Song, D.2    O'Regan, M.H.3
  • 43
    • 0030043546 scopus 로고    scopus 로고
    • Cerebroprotective action of the phospholipase inhibitor quinacrine in the ischemia/reperfused gerbil hippocampus
    • Phillis J.W. Cerebroprotective action of the phospholipase inhibitor quinacrine in the ischemia/reperfused gerbil hippocampus. Life Sci. 58:1996;PL97-PL101.
    • (1996) Life Sci. , vol.58
    • Phillis, J.W.1
  • 44
    • 0030593639 scopus 로고    scopus 로고
    • Mechanisms of glutamate and aspartate release in the ischemic rat cerebral cortex
    • Phillis J.W., O'Regan M.H. Mechanisms of glutamate and aspartate release in the ischemic rat cerebral cortex. Brain Res. 730:1996;150-160.
    • (1996) Brain Res. , vol.730 , pp. 150-160
    • Phillis, J.W.1    O'Regan, M.H.2
  • 46
    • 0037087156 scopus 로고    scopus 로고
    • ++ exchange by CGP-37157 attenuates free fatty acid efflux in rat cerebral cortex during ischemia-reperfusion injury
    • ++ exchange by CGP-37157 attenuates free fatty acid efflux in rat cerebral cortex during ischemia-reperfusion injury. Neurosci. Lett. 321:2002;1-4.
    • (2002) Neurosci. Lett. , vol.321 , pp. 1-4
    • Pilitsis, J.G.1    Diaz, F.G.2    O'Regan, M.H.3    Phillis, J.W.4
  • 48
    • 0035929513 scopus 로고    scopus 로고
    • + exchange by SM-20220 attenuates free fatty acid efflux in rat cerebral cortex during ischemia-reperfusion injury
    • + exchange by SM-20220 attenuates free fatty acid efflux in rat cerebral cortex during ischemia-reperfusion injury. Brain Res. 913:2001;156-158.
    • (2001) Brain Res. , vol.913 , pp. 156-158
    • Pilitsis, J.G.1    Diaz, F.G.2    O'Regan, M.H.3    Phillis, J.W.4
  • 49
    • 0035914207 scopus 로고    scopus 로고
    • ++ exchange by KB-R7943, a novel selective antagonist, attenuates phosphoethanolamine and free fatty acid efflux in rat cerebral cortex during ischemia-reperfusion injury
    • ++ exchange by KB-R7943, a novel selective antagonist, attenuates phosphoethanolamine and free fatty acid efflux in rat cerebral cortex during ischemia-reperfusion injury. Brain Res. 916:2001;192-198.
    • (2001) Brain Res. , vol.916 , pp. 192-198
    • Pilitsis, J.G.1    Diaz, F.G.2    O'Regan, M.H.3    Phillis, J.W.4
  • 52
    • 0032579875 scopus 로고    scopus 로고
    • A light and electron microscopic study of cytoplasmic phospholipase A2 and cyclooxygenase-2 in the hippocampus after kainate lesions
    • Sandhya T.L., Ong W.Y., Horrocks L.A., Farooqui A.A. A light and electron microscopic study of cytoplasmic phospholipase A2 and cyclooxygenase-2 in the hippocampus after kainate lesions. Brain Res. 788:1998;223-231.
    • (1998) Brain Res. , vol.788 , pp. 223-231
    • Sandhya, T.L.1    Ong, W.Y.2    Horrocks, L.A.3    Farooqui, A.A.4
  • 54
    • 0031590634 scopus 로고    scopus 로고
    • Fatty acid-promoted mitochondrial permeability transition by membrane depolarization and binding to the ADP/ATP carrier
    • Schonfeld P., Bohnensack R. Fatty acid-promoted mitochondrial permeability transition by membrane depolarization and binding to the ADP/ATP carrier. FEBS Lett. 420:1997;167-170.
    • (1997) FEBS Lett. , vol.420 , pp. 167-170
    • Schonfeld, P.1    Bohnensack, R.2
  • 55
    • 0035853767 scopus 로고    scopus 로고
    • Arachidonic acid causes cell death through the mitochondrial permeability transition
    • Scorrano L., Penzo D., Petronilli V., Pagano F., Bernardi P. Arachidonic acid causes cell death through the mitochondrial permeability transition. J. Biol. Chem. 276:2001;12035-12040.
    • (2001) J. Biol. Chem. , vol.276 , pp. 12035-12040
    • Scorrano, L.1    Penzo, D.2    Petronilli, V.3    Pagano, F.4    Bernardi, P.5
  • 56
    • 0026761179 scopus 로고
    • Eicosanoid biosynthesis and mechanisms of action
    • Smith W.L. Eicosanoid biosynthesis and mechanisms of action. Am J. Physiol. 263:1992;181-191.
    • (1992) Am J. Physiol. , vol.263 , pp. 181-191
    • Smith, W.L.1
  • 58
    • 0028209776 scopus 로고
    • Ischemia-induced changes in cerebral mitochondrial free fatty acids, phospholipids, and respiration in the rat
    • Sun D., Gilboe D.D. Ischemia-induced changes in cerebral mitochondrial free fatty acids, phospholipids, and respiration in the rat. J. Neurochem. 62:1994;1921-1928.
    • (1994) J. Neurochem. , vol.62 , pp. 1921-1928
    • Sun, D.1    Gilboe, D.D.2
  • 59
    • 0024469130 scopus 로고
    • Deacylation-reacylation of arachidonoyl groups in cerebral phospholipds
    • Sun G.Y., MacQuarrie R.A. Deacylation-reacylation of arachidonoyl groups in cerebral phospholipds. Ann. NY Acad. Sci. 559:1989;37-55.
    • (1989) Ann. NY Acad. Sci. , vol.559 , pp. 37-55
    • Sun, G.Y.1    MacQuarrie, R.A.2
  • 60
    • 0026094280 scopus 로고
    • A possible mechanism of mitochondrial dysfunction during cerebral ischemia: Inhibition of mitochondrial respiration activity by arachidonic acid
    • Takeuchi Y., Morii H., Tamura M., Hayaishi O., Watanabe Y. A possible mechanism of mitochondrial dysfunction during cerebral ischemia: Inhibition of mitochondrial respiration activity by arachidonic acid. Arch. Biochem. Biophys. 289:1991;33-38.
    • (1991) Arch. Biochem. Biophys. , vol.289 , pp. 33-38
    • Takeuchi, Y.1    Morii, H.2    Tamura, M.3    Hayaishi, O.4    Watanabe, Y.5
  • 61
    • 0021244526 scopus 로고
    • Effects of oleate on neurotransmitter transport and other plasma membrane functions in rat brain synaptosomes
    • Troeger M.B., Rafalowska U., Erecinska M. Effects of oleate on neurotransmitter transport and other plasma membrane functions in rat brain synaptosomes. J. Neurochem. 42:1984;1735-1742.
    • (1984) J. Neurochem. , vol.42 , pp. 1735-1742
    • Troeger, M.B.1    Rafalowska, U.2    Erecinska, M.3
  • 62
    • 0026612364 scopus 로고
    • 2 and C on free fatty acid release during complete ischemia in rat neocortex
    • 2 and C on free fatty acid release during complete ischemia in rat neocortex. J. Neurosurg. 76:1992;648-651.
    • (1992) J. Neurosurg. , vol.76 , pp. 648-651
    • Umemura, A.1    Mabe, H.2    Nagai, H.3    Sugino, F.4
  • 63
    • 0023187307 scopus 로고
    • Regional differences in arachidonic acid release in rat hippocampal CA1 and CA3 regions during cerebral ischemia
    • Westerberg E., Deshpande J.K., Wieloch T. Regional differences in arachidonic acid release in rat hippocampal CA1 and CA3 regions during cerebral ischemia. J. Cereb. Blood Flow Metab. 7:1987;189-192.
    • (1987) J. Cereb. Blood Flow Metab. , vol.7 , pp. 189-192
    • Westerberg, E.1    Deshpande, J.K.2    Wieloch, T.3
  • 64
    • 0031016799 scopus 로고    scopus 로고
    • ++ following intense glutamate stimulation of cultured forebrain neurons
    • ++ following intense glutamate stimulation of cultured forebrain neurons. J. Physiol. (Lond.). 498:1997;31-47.
    • (1997) J. Physiol. (Lond.) , vol.498 , pp. 31-47
    • White, R.J.1    Reynolds, I.J.2
  • 65
    • 0034602536 scopus 로고    scopus 로고
    • Long-chain fatty acids promote opening of the reconstituted mitochondrial permeability transition pore
    • Wieckowski M.R., Brdiczka D., Wojtczak L. Long-chain fatty acids promote opening of the reconstituted mitochondrial permeability transition pore. FEBS Lett. 484:2000;61-64.
    • (2000) FEBS Lett. , vol.484 , pp. 61-64
    • Wieckowski, M.R.1    Brdiczka, D.2    Wojtczak, L.3
  • 66
    • 0032570563 scopus 로고    scopus 로고
    • Fatty acid-induced uncoupling of oxidative phosphorylation is partly due to opening of the mitochondrial permeability transition pore
    • Wieckowski M.R., Wojtczak L. Fatty acid-induced uncoupling of oxidative phosphorylation is partly due to opening of the mitochondrial permeability transition pore. FEBS Lett. 423:1998;339-342.
    • (1998) FEBS Lett. , vol.423 , pp. 339-342
    • Wieckowski, M.R.1    Wojtczak, L.2
  • 67
    • 0017293611 scopus 로고
    • Effects of long-chain fatty acids and acyl-CoA on mitochondrial permeability, transport, and energy-coupling processes
    • Wojtczak L. Effects of long-chain fatty acids and acyl-CoA on mitochondrial permeability, transport, and energy-coupling processes. J. Bioenerg. Biomembr. 8:1976;293-311.
    • (1976) J. Bioenerg. Biomembr. , vol.8 , pp. 293-311
    • Wojtczak, L.1
  • 70
  • 71
    • 0028911077 scopus 로고
    • Differential modulation of human glutamate transporter subtypes by arachidonic acid
    • Zerangue N., Arriza J.L., Amar S.G., Kavanaugh M.P. Differential modulation of human glutamate transporter subtypes by arachidonic acid. J. Biol. Chem. 270:1995;6433-6435.
    • (1995) J. Biol. Chem. , vol.270 , pp. 6433-6435
    • Zerangue, N.1    Arriza, J.L.2    Amar, S.G.3    Kavanaugh, M.P.4
  • 72
    • 0033121301 scopus 로고    scopus 로고
    • ++ release from mitochondria
    • ++ release from mitochondria. J. Neurosci. 19:1999;3307-3315.
    • (1999) J. Neurosci. , vol.19 , pp. 3307-3315
    • Zhang, Y.1    Lipton, P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.