Integrating clinical trial data into clinical practice

Neurology

Volumn 58, Issue 12 SUPPL. 7, 2002, Pages

  Glauser, Tracy A ^a  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICONVULSIVE AGENT; ETIRACETAM; FELBAMATE; GABAPENTIN; LAMOTRIGINE; OXCARBAZEPINE; TOPIRAMATE; VIGABATRIN; ZONISAMIDE;

ADOLESCENT; BENIGN CHILDHOOD EPILEPSY; BLOOD TOXICITY; CHILD; CLINICAL TRIAL; DRUG DESIGN; DRUG EFFICACY; DRUG RESEARCH; DRUG TOLERABILITY; EPILEPSY; HUMAN; LIVER TOXICITY; META ANALYSIS; PRIORITY JOURNAL; REVIEW; SKIN TOXICITY;

EID: 0037172906     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/wnl.58.12_suppl_7.s6     Document Type: Review

References (53)

1. Felbamate for partial seizures: Results of a controlled clinical trial
2. Gabapentin (Neurontin) as add-on therapy in patients with partial seizures: A double-blind, placebo-controlled study
3. Gabapentin in partial epilepsy
4. Gabapentin as add-on therapy in refractory partial epilepsy: A double-blind, placebo-controlled, parallel-group study
5. Lamotrigine therapy for partial seizures: A multicenter, placebo-controlled, double-blind, cross-over trial
6. Topiramate
7. Topiramate placebo-controlled dose-ranging trial in refractory partial epilepsy using 200-, 400-, and 600-mg daily dosages
8. Topiramate as add-on therapy: Pooled analysis of randomized controlled trials in adults
9. Tiagabine for complex partial seizures: A randomized, add-on, dose-response trial
10. A double-blind, placebo-controlled trial of tiagabine given three times daily as add-on therapy for refractory partial seizures
11. Tiagabine therapy for complex partial seizures. A dose-frequency study
12. Randomized controlled trial of zonisamide for the treatment of refractory partial-onset seizures
13. Zonisamide for add-on treatment of refractory partial epilepsy: A European double-blind trial
14. Oxcarbazepine placebo-controlled, dose-ranging trial in refractory partial epilepsy
15. A multicentre, double-blind, randomized, parallel group study to evaluate the tolerability and efficacy of two oral doses of levetiracetam, 2000 mg daily and 4000 mg daily, without titration in patients with refractory epilepsy
16. Levetiracetam for partial seizures: Results of a double-blind, randomized clinical trial
17. Multicenter double-blind, randomized, placebo-controlled trial of levetiracetam as add-on therapy in patients with refractory partial seizures
18. Efficacy and tolerability of 1000-4000 mg per day of levetiracetam as add-on therapy in patients with refractory epilepsy
19. Monotherapy trials of new antiepileptic drugs
20. Felbamate monotherapy: Controlled trial in patients with partial onset seizures
21. A double-blind trial of gabapentin monotherapy for newly diagnosed partial seizures
22. Lamotrigine monotherapy in newly diagnosed untreated epilepsy: A double-blind comparison with phenytoin
23. An active-control trial of lamotrigine monotherapy for partial seizures
24. Topiramate monotherapy for partial onset seizures
25. Oxcarbazepine: Double-blind, randomized, placebo-control, monotherapy trial for partial seizures
26. A double-blind controlled clinical trial of oxcarbazepine versus phenytoin in adults with previously untreated epilepsy
27. A double-blind controlled clinical trial: Oxcarbazepine versus sodium valproate in adults with newly diagnosed epilepsy
28. Drug treatment in children
29. Gabapentin as add-on therapy in children with refractory partial seizures: A 12-week, multicentre, double-blind, placebo-controlled study
30. A placebo-controlled trial of lamotrigine add-on therapy for partial seizures in children
31. Adjunctive therapy with oxcarbazepine in children with partial seizures
32. A double-blind, randomized trial of topiramate as adjunctive therapy for partial-onset seizures in children
33. A randomized, placebo-controlled study of topiramate in primary generalized tonicclonic seizures
34. Efficacy of felbamate in childhood epileptic encephalopathy (Lennox-Gastaut syndrome)
35. Lamotrigine for generalized seizures associated with the Lennox-Gastaut syndrome
36. The efficacy of lamotrigine in children and adolescents with refractory generalized epilepsy: A randomized, double-blind, crossover study
37. A double-blind, randomized trial of topiramate in Lennox-Gastaut syndrome
38. Lamictal (lamotrigine) monotherapy for typical absence seizures in children
39. Gabapentin (Neurontin) monotherapy in children with benign childhood epilepsy with centrotemporal spikes (BECTS): A 36-week, double-blind, placebo-controlled study
40. Randomised, placebo-controlled study of vigabatrin as first-line treatment of infantile spasms
41. A double-blind controlled clinical trial of oxcarbazepine versus phenytoin in children and adolescents with epilepsy
42. Monotherapy in newly diagnosed epilepsy: Findings in the pediatric subset of a comparative study of topiramate, carbamazepine, and valproate
43. Long term efficacy and safety of adjunctive oxcarbazepine therapy in children with partial onset seizures
44. Effectiveness, tolerability, and safety of topiramate in children with partial-onset seizures
45. Nonfocal generalized tonic-clonic seizures: Response during long-term topiramate treatment
46. Topiramate in Lennox-Gastaut syndrome: Open-label treatment of patients completing a randomized controlled trial
47. Efficacy and safety of levetiracetam in children with partial seizures: An open-label trial
48. Levetiracetam, a pyrrolidone drug recently licensed as an antiepileptic
49. Idiosyncratic drug reactions: A mechanistic evaluation of risk factors
50. The role of active metabolites in drug toxicity
51. Idiosyncratic reactions: New methods of identifying high-risk patients
52. New concepts in immunology relevant to idiosyncratic drug reactions: The "danger hypothesis" and innate immune system
53. If nothing goes wrong, is everything all right? Interpreting zero numerators