Topiramate in lennox-gastaut syndrome: Open-label treatment of patients completing a randomized controlled trial

Epilepsia

Volumn 41, Issue SUPPL. 1, 2000, Pages 86-90

  Glauser, Tracy A ^a   Levisohn, Paul M ^b   Ritter, Frank ^c   Sachdeo, Rǎjesh C ^d  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b CHILDREN S HOSPITAL   (United States)

^c MINNESOTA EPILEPSY GROUP   (United States)

^d ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

Antiepileptic; Lennox Gastaut syndrome; Topiramate

Indexed keywords

TOPIRAMATE;

ADOLESCENT; ADULT; ANOREXIA; ARTICLE; CHILD; CLINICAL TRIAL; FEMALE; HUMAN; LENNOX GASTAUT SYNDROME; LONG TERM CARE; MAJOR CLINICAL STUDY; MALE; NEUROLOGIC DISEASE; PRIORITY JOURNAL;

ADOLESCENT; ADULT; ANTICONVULSANTS; CHILD; CHILD, PRESCHOOL; DOUBLE-BLIND METHOD; DRUG ADMINISTRATION SCHEDULE; DRUG THERAPY, COMBINATION; EPILEPSY; FEMALE; FRUCTOSE; HUMANS; MALE; PLACEBOS; TREATMENT OUTCOME;

EID: 17044452240     PISSN: 00139580     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1528-1157.2000.tb02179.x     Document Type: Article

References (8)

1. Wheless JW, Constantinou JEC. Lennox-Gastaut syndrome. Pediatr Neurol 1997;17:203-11.
2. Dulac O, N'Guyen T. The Lennox-Gastaut syndrome. Epilepsia 1993;34(suppl 7):S7-17.
3. Bourgeois BFD. Pharmacologic intervention and treatment of childhood seizure disorders: relative safety and efficacy of antiepileptic drugs. Epilepsia 1994;35(suppl 2):S18-23.
4. Perucca E, Gram L, Avanzini G, Dulac O. Antiepileptic drugs as a cause of worsening seizures. Epilepsia 1998;39:5-17.
5. Covanis A, Gupta AK, Jeavons PM. Sodium valproate monotherapy and polytherapy. Epilepsia 1982;23:693-720.
6. Henricksen O, Johannessen SI. Clinical and pharmacokinetic observations on sodium valproate: a 5-year follow-up study in 100 children with epilepsy. Acta Neurol Scand 1982;65:504-23.
7. The Felbamate Study Group in Lennox-Gastaut Syndrome. Efficacy of felbamate in childhood epileptic encephalopathy (Lennox-Gastaut syndrome). N Engl J Med 1993;328:29-33.
8. Motte J, Trevathan E, Arvidsson JFV, Barrera MN, Mullens EL, Manasco P, and the Lamictal Lennox-Gastaut Study Group. Lamotrigine for generalized seizures associated with the Lennox-Gastaut syndrome. N Engl J Med 1997;337:1807-12.