Role of P53 functionality in the genotoxicity of metronidazole and its hydroxy metabolite

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 501, Issue 1-2, 2002, Pages 57-67

  Menendez D ^a   Bendesky, A ^b   Rojas, E ^a   Salamanca, F ^c   Ostrosky Wegman, P ^a  

^a UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^b UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^c HOSPITAL DE PEDIATRÍA   (Mexico)

Author keywords

Cell proliferation; Micronuclei; P53

Indexed keywords

1 (HYDROXYETHYL) 2 HYDROXYMETHYL 5 NITROIMIDAZOLE; DRUG METABOLITE; METRONIDAZOLE; NITROIMIDAZOLE DERIVATIVE; PROTEIN P53; UNCLASSIFIED DRUG;

ARTICLE; CARCINOGENICITY; CELL VIABILITY; CODON; CONTROLLED STUDY; DOSE RESPONSE; DRUG POTENCY; GENE EXPRESSION; GENOTOXICITY; HUMAN; HUMAN CELL; LYMPHOCYTE PROLIFERATION; MICRONUCLEUS; MICRONUCLEUS TEST; PRIORITY JOURNAL; PROTEIN INDUCTION; WESTERN BLOTTING;

ANTI-INFECTIVE AGENTS; CELL DIVISION; HELA CELLS; HUMANS; METRONIDAZOLE; MICRONUCLEI, CHROMOSOME-DEFECTIVE; OXIDATION-REDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0037171664     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(02)00012-X     Document Type: Article

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