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Volumn 277, Issue 34, 2002, Pages 30684-30689
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Mechanism of apoptosis induced by a new topoisomerase inhibitor through the generation of hydrogen peroxide
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Author keywords
[No Author keywords available]
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Indexed keywords
FLOW CYTOMETRY;
CELLS;
DNA;
DRUG PRODUCTS;
ELECTROPHORESIS;
ENZYME INHIBITION;
HYDROGEN PEROXIDE;
SUBSTRATES;
TUMORS;
ENZYMES;
6 [2 (DIMETHYLAMINO)ETHYLAMINO] 3 HYDROXY 7H INDENO[2,1 C]QUINOLIN 7 ONE;
CASPASE 3;
DNA FRAGMENT;
DNA TOPOISOMERASE INHIBITOR;
HYDROGEN PEROXIDE;
PROTEIN BCL 2;
REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;
APOPTOSIS;
ARTICLE;
CELL CLONE;
CONTROLLED STUDY;
DNA CLEAVAGE;
DRUG MECHANISM;
ENZYME ACTIVATION;
ENZYME ACTIVITY;
GEL ELECTROPHORESIS;
HUMAN;
HUMAN CELL;
INHIBITION KINETICS;
LEUKEMIA CELL LINE;
MEMBRANE POTENTIAL;
MITOCHONDRIAL MEMBRANE;
PRIORITY JOURNAL;
PROTEIN EXPRESSION;
AMINOQUINOLINES;
ANTINEOPLASTIC AGENTS;
APOPTOSIS;
DNA DAMAGE;
DNA TOPOISOMERASES, TYPE I;
ENZYME INHIBITORS;
HL-60 CELLS;
HUMANS;
HYDROGEN PEROXIDE;
INDENES;
NADPH OXIDASE;
POLY(ADP-RIBOSE) POLYMERASES;
PROTO-ONCOGENE PROTEINS C-BCL-2;
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EID: 0037163038
PISSN: 00219258
EISSN: None
Source Type: Journal
DOI: 10.1074/jbc.M204353200 Document Type: Article |
Times cited : (59)
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References (57)
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