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Volumn 277, Issue 34, 2002, Pages 30429-30435
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The myocardium-protective Gly-49 variant of the β1-adrenergic receptor exhibits constitutive activity and increased desensitization and down-regulation
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Author keywords
[No Author keywords available]
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Indexed keywords
AMINES;
CARDIOLOGY;
CELLS;
ENZYMES;
DESENSITIZATION;
BIOCHEMISTRY;
ADENYLATE CYCLASE;
BETA 1 ADRENERGIC RECEPTOR;
CATECHOLAMINE;
CYCLIC AMP;
GLYCINE;
ISOPRENALINE;
METOPROLOL;
ARTICLE;
BINDING KINETICS;
CELL MEMBRANE;
CONTROLLED STUDY;
DOWN REGULATION;
DRUG POTENCY;
ENZYME ACTIVATION;
ENZYME ACTIVITY;
GENE EXPRESSION;
GENETIC POLYMORPHISM;
GENETIC VARIABILITY;
GENOTYPE;
HEART FAILURE;
HUMAN;
HUMAN TISSUE;
INHIBITION KINETICS;
INTERNALIZATION;
LIGAND BINDING;
PRIORITY JOURNAL;
REGULATORY MECHANISM;
SURVIVAL RATE;
SYSTEMATIC DESENSITIZATION;
DOWN-REGULATION;
GENOTYPE;
GLYCINE;
GTP-BINDING PROTEINS;
HEART FAILURE, CONGESTIVE;
HUMANS;
METOPROLOL;
POLYMORPHISM, GENETIC;
RECEPTORS, ADRENERGIC, BETA-1;
STRUCTURE-ACTIVITY RELATIONSHIP;
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EID: 0037163005
PISSN: 00219258
EISSN: None
Source Type: Journal
DOI: 10.1074/jbc.M200681200 Document Type: Article |
Times cited : (204)
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References (34)
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