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0028847025
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Li, H.; Porter, K.; Huang, F.; Shaw, B. R. Nucleic Acids Res. 1995, 23, 4495.
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Li, H.1
Porter, K.2
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3
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0345706517
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For recent reviews see: a) Mesmaeker, A. D.; Haner, R.; Martin, P.; Moser, H. E. Acc. Chem. Res. 1995, 28, 366.
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Mesmaeker, A.D.1
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4
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0011836520
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Structural modifications toward improved antisense oligonucleotides
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Trainor, G.L., Ed.; ESCOM: Leiden
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b) Matteucci, M. Structural Modifications Toward Improved Antisense Oligonucleotides. In Perspectives in Drug Discovery and Design: Vol. 4: Antisense Therapeutics; Trainor, G.L., Ed.; ESCOM: Leiden, 1996; pp. 1-16.
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Matteucci, M.1
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6
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0343886717
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note
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3·SMe and ammonium hydroxide treatments. Although dinucleotides were readily synthesized in solution phase, extension even to trinucleotides was problematic due to the <10% coupling yield.
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7
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0343886716
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A very recent meeting abstract alludes to a similar approach. Sergueev, D.; Hasan, A.; Ramaswamy, M.; Shaw, B. R. International Roundtable: Nucleosides, Nucleotides and Their Biological Applications, 1996, 246.
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International Roundtable: Nucleosides, Nucleotides and their Biological Applications
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Sergueev, D.1
Hasan, A.2
Ramaswamy, M.3
Shaw, B.R.4
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11
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0023046847
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Froehler, B. C.; Ng, P. G.; Matteucci, M. D. Nucleic Acid Res. 1986, 14, 5399.
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Froehler, B.C.1
Ng, P.G.2
Matteucci, M.D.3
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12
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0001231603
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Kume, A.; Fuji, M.; Sekine, M.; Hata, T. J. Org. Chem. 1984, 49, 2139.
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Kume, A.1
Fuji, M.2
Sekine, M.3
Hata, T.4
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13
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0343886715
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note
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2-isobutyrylguanosine. Further optimization will be required in order to achieve the synthesis of boranophosphate ODN analogs containing all four native nucleosides.
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14
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0027737710
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Oligonucleoside boranophosphate (borane phosphate)
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Agrawal, S. Ed.; Humana Press Inc.: Totowa
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Shaw, B. R.; Madison, J.; Sood, A.; Spielvogel, B. F. Oligonucleoside Boranophosphate (Borane Phosphate). In Methods in Molecular Biology Vol. 20: Protocols for Oligonucleotides and Analogs; Agrawal, S. Ed.; Humana Press Inc.: Totowa, 1993; pp. 225-243.
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Methods in Molecular Biology Vol. 20: Protocols for Oligonucleotides and Analogs
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, pp. 225-243
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Shaw, B.R.1
Madison, J.2
Sood, A.3
Spielvogel, B.F.4
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15
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0025331617
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Lesnikowski, Z. J.; Jaworska, M.; Stec, W. J. Nucleic Acid Res. 1990, 18, 2109.
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Lesnikowski, Z.J.1
Jaworska, M.2
Stec, W.J.3
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