메뉴 건너뛰기




Volumn 38, Issue 28, 1997, Pages 4957-4960

Synthesis and hybridization study of a boranophosphate-linked oligothymidine deoxynucleotide

Author keywords

[No Author keywords available]

Indexed keywords

BORANE DERIVATIVE; DNA; OLIGODEOXYNUCLEOTIDE; RNA;

EID: 0030861430     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)01090-3     Document Type: Article
Times cited : (49)

References (15)
  • 4
    • 0011836520 scopus 로고    scopus 로고
    • Structural modifications toward improved antisense oligonucleotides
    • Trainor, G.L., Ed.; ESCOM: Leiden
    • b) Matteucci, M. Structural Modifications Toward Improved Antisense Oligonucleotides. In Perspectives in Drug Discovery and Design: Vol. 4: Antisense Therapeutics; Trainor, G.L., Ed.; ESCOM: Leiden, 1996; pp. 1-16.
    • (1996) Perspectives in Drug Discovery and Design: Vol. 4: Antisense Therapeutics , vol.4 , pp. 1-16
    • Matteucci, M.1
  • 6
    • 0343886717 scopus 로고    scopus 로고
    • note
    • 3·SMe and ammonium hydroxide treatments. Although dinucleotides were readily synthesized in solution phase, extension even to trinucleotides was problematic due to the <10% coupling yield.
  • 13
    • 0343886715 scopus 로고    scopus 로고
    • note
    • 2-isobutyrylguanosine. Further optimization will be required in order to achieve the synthesis of boranophosphate ODN analogs containing all four native nucleosides.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.