Differential role of IFN-γ-inducible protein 10 kDa in a cockroach antigen-induced model of allergic airway hyperreactivity: Systemic versus local effects

Journal of Immunology

Volumn 169, Issue 12, 2002, Pages 7045-7053

  Thomas, Molly S ^a   Kunkel, Steven L ^a   Lukacs, Nicholas W ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; CD4 ANTIGEN; CHEMOKINE RECEPTOR CXCR3; COCKROACH ANTIGEN; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; UNCLASSIFIED DRUG; ALLERGEN; ALLERGEN CRA, COCKROACH; ALPHA CHEMOKINE; ANTISERUM; CXC CHEMOKINE IP 10; CXC CHEMOKINE IP-10; CYTOKINE; GAMMA INTERFERON;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRONCHUS HYPERREACTIVITY; CONTROLLED STUDY; EOSINOPHIL; IMMUNE RESPONSE; IMMUNOMODULATION; INFLAMMATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; TH2 CELL; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; CELL MOTION; COCKROACH; COMPARATIVE STUDY; DISEASE MODEL; DRUG ANTAGONISM; ENDOTRACHEAL INTUBATION; IMMUNOLOGY; LEUKOCYTE COUNT; LUNG; LYMPH NODE; METABOLISM; PATHOLOGY; PHYSIOLOGY; RESPIRATORY TRACT ALLERGY;

ALLERGENS; ANIMALS; BRONCHIAL HYPERREACTIVITY; CELL MOVEMENT; CHEMOKINES, CXC; COCKROACHES; CYTOKINES; DISEASE MODELS, ANIMAL; EOSINOPHILS; IMMUNE SERA; INTERFERON TYPE II; INTUBATION, INTRATRACHEAL; LEUKOCYTE COUNT; LUNG; LYMPH NODES; MICE; MICE, INBRED BALB C; RESPIRATORY HYPERSENSITIVITY; TH2 CELLS;

EID: 0037114139     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.169.12.7045     Document Type: Article

References (42)

1. Christiansen, S. C., S. B. Martin, N. C, Schleicher, J. A. Koziol, R. G. Hamilton, and B. L. Zuraw. 1996. Exposure and sensitization to environmental allergen of predominantly Hispanic children with asthma in San Diego's inner city. J. Allergy Clin. Immunol, 98:288.
2. Rosenstreich, D. L., P. Eggleston, M. Kattan, D. Baker, R. G. Slavin, P. Gergen, H. Mitchell, K. McNiff-Mortimer, H, Lynn, D. Ownby, and F. Malveaux. 1997. The role of cockroach allergy and exposure to cockroach allergen in causing morbidity among inner-city children with asthma. N. Engl, J. Med. 336:1356.
3. Chiaramonte, M. G., L. R. Schopf, T. Y, Neben, A. W. Cheever, D. D. Donaldson, and T. A. Wynn. 1999. IL-13 is a key regulatory cytokine for Th2 cell-mediated pulmonary granuloma formation and IgE responses induced by Schistosoma mansoni eggs. J. Immunol. 162:920.
4. Kips, J. C., G. G. Brusselle, G. F. Joos, R, A. Peleman, R. R. Devos, J. H. Tavernier, and R. A. Pauwels. 1995. Importance of interleukin-4 and interleukin-12 in allergen-induced airway changes in mice. Int. Arch. Allergy Immunol. 107:115.
5. Li, L. Y. Xia, A. Nguyen, Y, H, Lai, L. Feng, T. R. Mosmann, and D. Lo, 1999. Effects of Th2 cytokines on chemokine expression in the lung: IL-13 potently induces eotaxin expression by airway epithelial cells, J. Immunol. 162:2477.
6. McKenzie, G. J., C. L. Emson, S. E. Bell, S. Anderson, P. Fallon, G. Zurawski, R. Murray, R. Grencis, and A. N, McKenzie, 1998. Impaired development of Th2 cells in IL-13-deficient mice. Immunity 9:423.
7. Zhu, Z., R. J, Homer, Z. Wang, Q. Chen, G, P. Geba, J. Wang, Y. Zhang, and J. A, Elias. 1999. Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production. J. Clin. Invest. 103:779.
8. Bonecchi, R., G. Bianchi, P. P. Bordignon, D. D'Ambrosio, R. Lang, A. Borsatti, S. Sozzani, P. Allavena, P. A. Gray, A. Mantovani, and F. Sinigaglia, 1998. Differential expression of chemokine receptors and chemotactic responsiveness of type I T helper cells (Th1s) and Th2s. J. Exp. Med. 187:129.
9. Holgate, S. T., P. M, Lackie. D. E. Davies, W. R. Roche, and A. F. Walls. 1999. The bronchial epithelium as a key regulator of airway inflammation and remodelling in asthma. Clin. Exp. Allergy 29(Suppl. 2):90.
10. Lukacs, N. W., C. Hogaboam, E. Campbell, and S. L. Kunkel. 1999. Chemokines: function, regulation and alteration of inflammatory responses. Chem. Immunol. 72:102.
11. Lukacs, N, W., R. M. Strieter, S. W. Chensue, and S, L. Kunkel. 1996, Activation and regulation of chemokines in allergic airway inflammation. J. Leukocyte Biol. 59:13.
12. Corrigan, C. J., and A. B. Kay. 1992. T cells and eosinophils in the pathogenesis of asthma. Immunol. Today 13:501.
13. Sauty, A., M. Dziejman, R. A. Taha, A. S. Iarossi, K, Neote, E. A. Garcia-Zepeda, Q. Hamid, and A. D. Luster. 1999. The T cell-specific CXC chemokines IP-10, Mig, and I-TAC are expressed by activated human bronchial epithelial cells. J. Immunol. 162:3549,
14. Farber, J. M. 1997. Mig and IP-10: CXC chemokines that target lymphocytes. J. Leukocyte Biol. 61:246.
15. Ebert, L. M., and S. R. McColl. 2001. Coregulation of CXC chemokine receptor and CD4 expression on T lymphocytes during allogeneic activation, J. Immunol. 166:4870.
16. Sauty, A., R. A, Colvin, L. Wagner, S, Rochat. F. Spertini, and A. D. Luster, 2001. CXCR3 internalization following T cell-endothelial cell contact: preferential role of IFN-inducible T cell α chemoattractant (CXCL11). J. Immunol. 167:7084.
17. Qin, S., J. B. Rottman, P. Myers, N. Kassam. M. Weinblatt, M, Loetscher, A. E. Koch, B. Moser, and C. R. Mackay. 1998. The chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions. J. Clin. Invest. 101:746.
18. Annunziato, F., L. Cosmi, G, Galli, C. Beltrame, P. Romagnani, R. Manetti, S, Romagnani, and E. Maggi. 1999. Assessment of chemokine receptor expression by human Th1 and Th2 cells in vitro and in vivo. J. Leukocyte Biol. 65:691.
19. Yuan, Y. H., T. ten Hove, F. O. The, J. F. Slors, S. J, van Deventer, and A. A. te Velde. 2001. Chemokine receptor CXCR3 expression in inflammatory bowel disease. Inflamm. Bowel Dis. 7:281.
20. Misu. T., H. Onodera, K. Fujihara, K. Matsushima, O. Yoshie, N. Okita, S. Takase, and Y. Itoyama. 2001. Chemokine receptor expression on T cells in blood and cerebrospinal fluid at relapse and remission of multiple sclerosis: imbalance of Th1/Th2-associated chemokine signaling. J. Neuroimmunol. 114:207.
21. Patel, D. D., J. P. Zachariah, and L. P. Whichard. 2001. CXCR3 and CCR5 ligands in rheumatoid arthritis synovium. Clin. Immunol. 98:39.
22. Li, X. M., R. K. Chopra, T. Y. Chou, B. H. Schofield, M. Wills-Karp, and S. K. Huang. 1996. Mucosal IFN-γ gene transfer inhibits pulmonary allergic responses in mice. J. Immunol. 157:3216.
23. Cohn, L., R. J. Homer, N. Niu, and K. Bottomly. 1999. T helper I cells and interferon y regulate allergic airway inflammation and mucus production. J. Exp. Med. 190:1309.
24. Biedermann, T., R. Mailhammer, A. Mai, C. Sander, A. Ogilvie, F. Brombacher, K. Maier, A. D. Levine, and M. Rocken. 2001. Reversal of established delayed type hypersensitivity reactions following therapy with IL-4 or antigen-specific Th2 cells. Eur. J. Immunol. 31:1582.
25. Toumoy, K. G., J. C. Kips, and R. A. Pauwels. 2001. Counterbalancing of TH2-driven allergic airway inflammation by IL-12 does not require IL-10. J. Allergy Clin. Immunol 107:483.
26. Cohn, L., C. Herrick, N. Niu, R. Homer, and K. Bottomly. 2001. IL-4 promotes airway eosinophilia by suppressing IFN-γ production: defining a novel role for IFN-γ in the regulation of allergic airway inflammation. J. Immunol. 166:2760.
27. Ford, J. G., D. Rennick, D. D. Donaldson, R. Venkayya, C. McArthur, E. Hansell, V. P. Kurup, M. Warnock, and G. Grunig. 2001. IL-13 and IFN-γ: interactions in lung inflammation. J. Immunol. 167:1769.
28. Gavett, S. H., D. J. O'Heam, X. Li, S. K. Huang, F. D. Finkelman, and M. Wills-Karp. 1995. Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine expression in mice. J. Exp. Med. 182:1527.
29. Wiley, R., K. Palmer, B. Gajewska, M. Stampfli, D. Alvarez, A. Coyle, J. Gutierrez-Ramos, and M. Jordana. 2001. Expression of the Th1 chemokine IFN-γ-inducible protein 10 in the airway alters mucosal allergic sensitization in mice. J. Immunol. 166:2750.
30. Lukacs, N. W., R. M. Strieter, K. Warmington, P. Liacoln, S. W. Chensue. and S. L. Kunkel. 1997. Differential recruitment of leukocyte populations and alteration of airway hyperreactivity by C-C family chemokines in allergic airway inflammation. J. Immunol. 158:4398.
31. Campbell, E., S. L. Kunkel, R. M. Strieter, and N. W. Lukacs. 2000. Differential roles of IL-18 in allergic airway disease: induction of eotaxin by resident cell populations exacerbates eosinophil accumulation. J. Immunol. 164:1096.
32. Medoff, B. D., A. Sauty, A. Tager, J. A. Maclean, R. N. Smith, A. Mathew, J. H. Doufour, and A. D. Luster, 2002. IFN-γ-inducible protein 10 (CXCL10) contributes to airway hyperractivity and airway inflammation in a mouse model of asthma. J. Immunol. 168:5278.
33. Tang, C., M. D. Inman, N. van Rooijen, P. Yang, H. Shen, K. Matsumoto, and P. M. O'Byrne. 2001. Th type 1-stimulating activity of lung macrophages inhibits Th2-mediated allergic airway inflammation by an IFN-γ-dependent mechanism. J. Immunol. 166:1471.
34. Dufour, J. H., M. Dziejman, M. T. Liu, J. H. Leung, T. E. Lane, and A. D. Luster. 2002. IFN-γ-inducible protein 10 (IP-10; CXCL10)-deficient mice reveal a role for IP-10 in effector T cell generation and trafficking. J. Immunol. 168:3195.
35. Burdin, N., L. Brossay, and M. Kronenberg. 1999. Immunization with a-galactosylceramide polarizes CD1-reactive NK T cells towards Th2 cytokine synthesis. Eur. J. Immunol. 29:2014.
36. Korsgren, M., C. G. Persson, F. Sundler, T. Bjerke, T. Hansson, B. J. Chambers, S. Hong, L. Van Kaer, H. G. Ljunggren, and O. Korsgren. 1999. Natural killer cells determine development of allergen- induced eosinophilic airway inflammation in mice. J. Exp. Med. 189:553.
37. Kim, C. H., L. Rott, E. J. Kunkel, M. C. Genovese, D. P. Andrew, L. Wu, and E. C. Butcher. 2001. Rules of chemokine receptor association with T cell polarization in vivo. J. Clin. Invest. 108:1331.
38. Inngjerdingen, M., B. Damaj, and A. A. Maghazachi. 2001. Expression and regulation of chemokine receptors in human natural killer cells. Blood 97:367.
39. Rabin, R. L., M. K. Park, F. Liao, R. Swofford, D. Stephany, and J. M. Farber. 1999. Chemokine receptor responses on T cells are achieved through regulation of both receptor expression and signaling. J. Immunol. 162:3840.
40. H2 cytokine expression by individual memory T cells. Int. Immunol. 12:1659.
41. Nutku, E., Q. Zhuang, A. Soussi-Gounni, F. Aris, B. D. Mazer, and Q. Hamid. 2001. Functional expression of IL-12 receptor by human eosinophils: IL-12 promotes eosinophil apoptosis. J. Immunol. 167:1039.
42. Jinquan, T., C. Jing, H. H. Jacobi, C. M. Reimert, A. Millner, S. Quan, J. B. Hansen, S. Dissing, H. J. Malling, P. S. Skov, and L. K. Poulsen. 2000. CXCR3 expression and activation of eosinophils: role of IFN-γ-inducible protein-10 and monokine induced by IFN-γ, J. Immunol. 165:1548.