Evidence for crucial electrostatic interactions between Bcl-2 homology domains BH3 and BH4 in the anti-apoptotic Nr-13 protein

Biochemical Journal

Volumn 368, Issue 1, 2002, Pages 213-221

  Lalle, Philippe ^a   Aouacheria, Abdel ^a   Dumont Miscopein, Agnès ^a   Jambon, Martin ^a   Venet, Séverine ^a   Bobichon, Hélène ^b   Colas, Pierre ^c   Deléage, Gilbert ^a   Geourjon, Christophe ^a   Gillet, Germain ^a  

^a INSTITUT DE BIOLOGIE ET CHIMIE DES PROTÉINES   (France)

^b CNRS   (France)

^c UNIVERSITÉ DE LYON   (France)

Author keywords

Apoptosis; Bcl 2; Nr 13

Indexed keywords

CELLS; ELECTROSTATICS; MUTAGENESIS; PROTEINS; YEAST;

ENERGY MINIMIZATION;

BIOCHEMISTRY;

PROTEIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN NR 13; UNCLASSIFIED DRUG;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ANIMAL CELL; APOPTOSIS; ARTICLE; BINDING SITE; CELLULAR DISTRIBUTION; CIRCULAR DICHROISM; CONTROLLED STUDY; CYTOTOXICITY; ELECTRICITY; IMMUNOHISTOCHEMISTRY; MOLECULAR INTERACTION; MOLECULAR MODEL; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PROTEIN INTERACTION; RAT; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; AVIAN PROTEINS; CELLS, CULTURED; CHICKENS; COS CELLS; ELECTROSTATICS; MEMBRANE PROTEINS; MICE; MODELS, MOLECULAR; MUTATION; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; SEQUENCE HOMOLOGY, AMINO ACID; SUBCELLULAR FRACTIONS;

ANIMALIA; VERTEBRATA;

EID: 0037113176     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20020836     Document Type: Article

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