Dissociation of Bax from a Bcl-2/Bax heterodimer triggered by phosphorylation of serine 70 of Bcl-21

Journal of Biochemistry

Volumn 130, Issue 6, 2001, Pages 741-748

  Shitashige, Miki ^a,b   Toi, Masakazu ^c   Yano, Takeo ^d   Shibata, Masao ^d   Matsuo, Yoshinobu ^e   Shibasaki, Futoshi ^a  

^a TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c TOKYO METROPOLITAN KOMAGOME HOSPITAL   (Japan)

^d Med Biological Labs Ina Laboratory   (Japan)

^e HAYASHIBARA BIOCHEMICAL LABORATORIES INC   (Japan)

Author keywords

Apoptosis; Bcl 2; Breast cancer; Paclitaxel (Taxol); Phosphorylation

Indexed keywords

ANTINEOPLASTIC AGENT; CYCLOHEXIMIDE; DACTINOMYCIN; DOCETAXEL; PACLITAXEL; PHOSPHOTRANSFERASE; PROTEIN ANTIBODY; PROTEIN BAX; PROTEIN BCL 2; SERINE;

ADULT; AGED; ANIMAL CELL; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER TISSUE; CELL DEATH; CELL STRAIN BHK; CELL VIABILITY; CLINICAL ARTICLE; CONTROLLED STUDY; DISSOCIATION; DRUG SENSITIVITY; HUMAN; HUMAN CELL; HUMAN TISSUE; NONHUMAN; PREDICTION; PROGNOSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BREAST NEOPLASMS; BURKITT LYMPHOMA; CELL LINE; CELL SURVIVAL; CRICETINAE; CYTOCHROME C GROUP; DIMERIZATION; FIBROBLASTS; HUMANS; KIDNEY; MESOCRICETUS; MITOCHONDRIA; PACLITAXEL; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; SERINE; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 0035663296     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a003044     Document Type: Article

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