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Volumn 27, Issue 22, 2002, Pages 2526-2537

Physiology of chronic spinal pain syndromes: From animal models to biomechanics

Author keywords

Animal model; Biomechanics; Nociception; Pain

Indexed keywords

BIOMECHANICS; CHRONIC PAIN; CLINICAL FEATURE; CONCEPT FORMATION; CONFERENCE PAPER; DIAGNOSTIC APPROACH ROUTE; DISEASE MODEL; GENDER; GENETICS; HUMAN; MEDICAL RESEARCH; NERVE ROOT; NOCICEPTION; PRACTICE GUIDELINE; PRIORITY JOURNAL; RADICULOGRAPHY; RADICULOPATHY; SPINE DISEASE; SYMPTOMATOLOGY;

EID: 0037111854     PISSN: 03622436     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007632-200211150-00026     Document Type: Conference Paper
Times cited : (74)

References (63)
  • 1
    • 0023895875 scopus 로고
    • A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man
    • Bennett GJ, Xie YK. A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man. Pain 1988;33:87-107.
    • (1988) Pain , vol.33 , pp. 87-107
    • Bennett, G.J.1    Xie, Y.K.2
  • 3
    • 0028577356 scopus 로고
    • Tumor necrosis factor alpha potentiates glutamate neurotoxicity in human fetal brain cell cultures
    • Chao C, Hu S. Tumor necrosis factor alpha potentiates glutamate neurotoxicity in human fetal brain cell cultures. Dev Neurosci 1994;16:172-9.
    • (1994) Dev Neurosci , vol.16 , pp. 172-179
    • Chao, C.1    Hu, S.2
  • 4
    • 0026928565 scopus 로고
    • The functional recovery of peripheral nerves following defined acute crush injuries
    • Chen L, Seaber A, Glisson R, et al. The functional recovery of peripheral nerves following defined acute crush injuries. J Orthop Res 1992;10:657-64.
    • (1992) J Orthop Res , vol.10 , pp. 657-664
    • Chen, L.1    Seaber, A.2    Glisson, R.3
  • 5
    • 0027163215 scopus 로고
    • The influence of magnitude and duration of crush load on functional recovery of the peripheral nerve
    • Chen L, Seaber A, Urbanak J. The influence of magnitude and duration of crush load on functional recovery of the peripheral nerve. J Reconstr Microsurg 1993;9:299-307.
    • (1993) J Reconstr Microsurg , vol.9 , pp. 299-307
    • Chen, L.1    Seaber, A.2    Urbanak, J.3
  • 6
    • 0032978701 scopus 로고    scopus 로고
    • The effect of site and type of nerve injury on spinal glial activation and neuropathic pain behavior
    • Colburn R, Rickman A, DeLeo J. The effect of site and type of nerve injury on spinal glial activation and neuropathic pain behavior. Exp Neurol 1999;157:289-304.
    • (1999) Exp Neurol , vol.157 , pp. 289-304
    • Colburn, R.1    Rickman, A.2    DeLeo, J.3
  • 7
    • 0023157121 scopus 로고
    • Dynamic receptive field plasticity in rat spinal cord dorsal horn following C primary afferent input
    • Cook AJ, Woolf CJ, Wall PD, et al. Dynamic receptive field plasticity in rat spinal cord dorsal horn following C primary afferent input. Nature 1987; 325:151-3.
    • (1987) Nature , vol.325 , pp. 151-153
    • Cook, A.J.1    Woolf, C.J.2    Wall, P.D.3
  • 8
    • 0033955244 scopus 로고    scopus 로고
    • Immunolocalizarion of SNS/PN3 and NaN/SNS2 sodium channels in human pain states
    • Coward K, Plumpton C, Facer P, et al. Immunolocalizarion of SNS/PN3 and NaN/SNS2 sodium channels in human pain states. Pain 2000;85:41-50.
    • (2000) Pain , vol.85 , pp. 41-50
    • Coward, K.1    Plumpton, C.2    Facer, P.3
  • 9
    • 0002747405 scopus 로고    scopus 로고
    • The role of cytokines in nociception and chronic pain
    • Weinstein JN, Gordon SL, eds. Rosemonr, IL: AAOS Publishers
    • DeLeo JA, Colburn RW. The role of cytokines in nociception and chronic pain. In: Weinstein JN, Gordon SL, eds. Low Back Pain: A Scientific and Clinical Overview. Rosemonr, IL: AAOS Publishers, 1996:163-85.
    • (1996) Low Back Pain: A Scientific and Clinical Overview , pp. 163-185
    • DeLeo, J.A.1    Colburn, R.W.2
  • 10
    • 0028040335 scopus 로고
    • Characterization of a neuropathic pain model: Sciatic cryoneurolysis in the rat
    • DeLeo JA, Coombs DW, Willenbring SW, et al. Characterization of a neuropathic pain model: Sciatic cryoneurolysis in the rat. Pain 1994;56:9-16.
    • (1994) Pain , vol.56 , pp. 9-16
    • DeLeo, J.A.1    Coombs, D.W.2    Willenbring, S.W.3
  • 11
    • 0035252354 scopus 로고    scopus 로고
    • The role of neuroinflammation and neuroimmune activation in persistent pain
    • DeLeo JA, Yezierski RP. The role of neuroinflammation and neuroimmune activation in persistent pain. Pain 2001;91:1-6.
    • (2001) Pain , vol.91 , pp. 1-6
    • DeLeo, J.A.1    Yezierski, R.P.2
  • 12
    • 0027532297 scopus 로고
    • Bradykinin and inflammatory pain
    • Dray A, Perkins M. Bradykinin and inflammatory pain. Trends Neurosci 1993;16:99-104.
    • (1993) Trends Neurosci , vol.16 , pp. 99-104
    • Dray, A.1    Perkins, M.2
  • 13
    • 0024804930 scopus 로고
    • The neurobiology of pain and its modulation
    • Dubner R, Hargreaves KM. The neurobiology of pain and its modulation. Clin J Pain 1989;2(Suppl):S1-6.
    • (1989) Clin J Pain , vol.2 , Issue.SUPPL.
    • Dubner, R.1    Hargreaves, K.M.2
  • 14
    • 0023924046 scopus 로고
    • A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia
    • Hargreaves K, Dubner R, Brown F, et al. A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain 1988;32:77-88.
    • (1988) Pain , vol.32 , pp. 77-88
    • Hargreaves, K.1    Dubner, R.2    Brown, F.3
  • 15
    • 0034657820 scopus 로고    scopus 로고
    • Spinal glial activation and cytokine expression after lumbar root injury in the rat
    • Hashizume H, DeLeo JA, Colburn RW, et al. Spinal glial activation and cytokine expression after lumbar root injury in the rat. Spine 2000;25:1206-17.
    • (2000) Spine , vol.25 , pp. 1206-1217
    • Hashizume, H.1    DeLeo, J.A.2    Colburn, R.W.3
  • 16
    • 0024551783 scopus 로고
    • Long-term changes in discharge behavior of cat dorsal horn neurons following noxious stimulation of deep tissues
    • Hoheisel U, Mense S. Long-term changes in discharge behavior of cat dorsal horn neurons following noxious stimulation of deep tissues. Pain 1989;36:239-47.
    • (1989) Pain , vol.36 , pp. 239-247
    • Hoheisel, U.1    Mense, S.2
  • 17
    • 0011391375 scopus 로고    scopus 로고
    • Show me where it hurts: Tracing the pathway of pain
    • Hopkin K. Show me where it hurts: Tracing the pathway of pain. J NIH Res 1997;9:37-43.
    • (1997) J NIH Res , vol.9 , pp. 37-43
    • Hopkin, K.1
  • 18
    • 0033991143 scopus 로고    scopus 로고
    • Differential regulation of cyclooxygenase (COX-2) mRNA stability by interleukin-1β and tumor necrosis factor-α in human in vitro differentiated macrophages
    • Huang Z-F, Massey JB, Via DP. Differential regulation of cyclooxygenase (COX-2) mRNA stability by interleukin-1β and tumor necrosis factor-α in human in vitro differentiated macrophages. Biochem Pharmacol 2000;59:187-94.
    • (2000) Biochem Pharmacol , vol.59 , pp. 187-194
    • Huang, Z.-F.1    Massey, J.B.2    Via, D.P.3
  • 19
    • 0034407331 scopus 로고    scopus 로고
    • Exogenous tumor necrosis factor-alpha mimics nucleus pulposus-induced neuropathology: Molecular, histologic, and behavioral comparisons in rats
    • Igatashi T, Kikuchi S, Shubayev V, et al. Exogenous tumor necrosis factor-alpha mimics nucleus pulposus-induced neuropathology: Molecular, histologic, and behavioral comparisons in rats. Spine 2000;25:2975-80.
    • (2000) Spine , vol.25 , pp. 2975-2980
    • Igatashi, T.1    Kikuchi, S.2    Shubayev, V.3
  • 20
    • 0032589741 scopus 로고    scopus 로고
    • Interleukin-1β induces substance P release from primary afferent neurons through the cyclooygenase-2 system
    • Inoue A, Ikoma K, Morioka N, et al. Interleukin-1β induces substance P release from primary afferent neurons through the cyclooygenase-2 system. J Neurochem 1999;73:2206-13.
    • (1999) J Neurochem , vol.73 , pp. 2206-2213
    • Inoue, A.1    Ikoma, K.2    Morioka, N.3
  • 21
    • 0033963153 scopus 로고    scopus 로고
    • Nociceptive and inflammatory effects of subcutaneous TNF alpha
    • Junger H, Sorkin LS. Nociceptive and inflammatory effects of subcutaneous TNF alpha. Pain 2000;85(1-2):145-51.
    • (2000) Pain , vol.85 , Issue.1-2 , pp. 145-151
    • Junger, H.1    Sorkin, L.S.2
  • 22
    • 0030483686 scopus 로고    scopus 로고
    • Cellular aspects of the inflammatory response in Alzheimer's disease
    • Kalaria R, Cohen D, Premkumar D. Cellular aspects of the inflammatory response in Alzheimer's disease. Neurodegenetation 1996;5:497-503.
    • (1996) Neurodegenetation , vol.5 , pp. 497-503
    • Kalaria, R.1    Cohen, D.2    Premkumar, D.3
  • 23
    • 0028072303 scopus 로고
    • Experimental lumbar radiculopathy: Behavioral and histological changes in a model of radicular pain after spinal nerve root irritation with chromic gut ligatures in the rat
    • Kawakami M, Weinstein JN, Chatani K, et al. Experimental lumbar radiculopathy: Behavioral and histological changes in a model of radicular pain after spinal nerve root irritation with chromic gut ligatures in the rat. Spine 1994;19:1795-802.
    • (1994) Spine , vol.19 , pp. 1795-1802
    • Kawakami, M.1    Weinstein, J.N.2    Chatani, K.3
  • 24
    • 0029856176 scopus 로고    scopus 로고
    • Incision of the anulus fibrosus induces nerve root morphologic, vascular, and functional changes: An experimental study
    • Kayama S, Konno S, Olmarker K, et al. Incision of the anulus fibrosus induces nerve root morphologic, vascular, and functional changes: An experimental study. Spine 1996;21:2539-43.
    • (1996) Spine , vol.21 , pp. 2539-2543
    • Kayama, S.1    Konno, S.2    Olmarker, K.3
  • 27
    • 0032143079 scopus 로고    scopus 로고
    • Chronic double-level cauda equina with analyses of nerve conduction velocity
    • Mao G, Konno S, Arai I, et al. Chronic double-level cauda equina with analyses of nerve conduction velocity. Spine 1998;23:1641-4.
    • (1998) Spine , vol.23 , pp. 1641-1644
    • Mao, G.1    Konno, S.2    Arai, I.3
  • 28
    • 0023226602 scopus 로고
    • The inflammatory effect of nucleus pulposus: A possible element in the pathogenesis of low back pain
    • McCarron RF, Wimpee MW, Hudkins P, et al. The inflammatory effect of nucleus pulposus: A possible element in the pathogenesis of low back pain. Spine 1987;12:760-4.
    • (1987) Spine , vol.12 , pp. 760-764
    • McCarron, R.F.1    Wimpee, M.W.2    Hudkins, P.3
  • 30
    • 0033529267 scopus 로고    scopus 로고
    • The genetic mediation of individual differences in sensitivity to pain and its inhibition
    • Mogil JS. The genetic mediation of individual differences in sensitivity to pain and its inhibition. Proc Natl Acad Sci U S A 1999;96:7744-51.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 7744-7751
    • Mogil, J.S.1
  • 31
    • 0031028773 scopus 로고    scopus 로고
    • Tumor necrosis factor enhances the capsaicin sensitivity of rat sensory neurons
    • Nicol GD, Lopshire JC, Pafford CM. Tumor necrosis factor enhances the capsaicin sensitivity of rat sensory neurons. J Neurosci 1997;17:975-82.
    • (1997) J Neurosci , vol.17 , pp. 975-982
    • Nicol, G.D.1    Lopshire, J.C.2    Pafford, C.M.3
  • 32
    • 0028930457 scopus 로고
    • A regulatory role for astrocytes in HIV-1 encephalitis: An overexpression of eicosanoids, platelet-activating factor, and tumor necrosis factor-alpha by activated HIV-1 infected monocytes is attenuated by primary human astrocytes
    • Nottet H, Jett M, Flanagan C, et al. A regulatory role for astrocytes in HIV-1 encephalitis: An overexpression of eicosanoids, platelet-activating factor, and tumor necrosis factor-alpha by activated HIV-1 infected monocytes is attenuated by primary human astrocytes. J Immunol 1995;154:3567-81.
    • (1995) J Immunol , vol.154 , pp. 3567-3581
    • Nottet, H.1    Jett, M.2    Flanagan, C.3
  • 33
    • 0025310684 scopus 로고
    • Importance of compression onset rate for the degree of impairment of impulse propagation in experimental compression injury of the porcine cauda equina
    • Olmarker K, Holm S, Rydevik B. Importance of compression onset rate for the degree of impairment of impulse propagation in experimental compression injury of the porcine cauda equina. Spine 1990;15:416-19.
    • (1990) Spine , vol.15 , pp. 416-419
    • Olmarker, K.1    Holm, S.2    Rydevik, B.3
  • 34
    • 0031770778 scopus 로고    scopus 로고
    • Pathogenesis of sciatic pain: Role of herniated nucleus pulposus and deformation of spinal nerve root and dorsal root ganglion
    • Olmarker K, Myers RR. Pathogenesis of sciatic pain: Role of herniated nucleus pulposus and deformation of spinal nerve root and dorsal root ganglion. Pain 1998;78:99-105.
    • (1998) Pain , vol.78 , pp. 99-105
    • Olmarker, K.1    Myers, R.R.2
  • 35
    • 0024391736 scopus 로고
    • Edema formation in spinal nerve roots induced by experimental, graded compression: An experimental study on the pig cauda equina with special reference to differences in effects between rapid and slow onset of compression
    • Olmarker K, Rydevik B, Holm S. Edema formation in spinal nerve roots induced by experimental, graded compression: An experimental study on the pig cauda equina with special reference to differences in effects between rapid and slow onset of compression. Spine 1989;14:569-73.
    • (1989) Spine , vol.14 , pp. 569-573
    • Olmarker, K.1    Rydevik, B.2    Holm, S.3
  • 36
    • 0024764106 scopus 로고
    • Effects of experimental graded compression on blood flow in spinal nerve roots: A vital microscopic study on the porcine cauda equina
    • Olmarker K, Rydevik B, Holm S, et al. Effects of experimental graded compression on blood flow in spinal nerve roots: A vital microscopic study on the porcine cauda equina. J Orthop Res 1989;7:817-23.
    • (1989) J Orthop Res , vol.7 , pp. 817-823
    • Olmarker, K.1    Rydevik, B.2    Holm, S.3
  • 37
    • 0027296826 scopus 로고
    • Autologous nucleus pulposus induces neurophysiologic and histologic changes in porcine cauda equina nerve roots
    • Olmarker K, Rydevik B, Nordborg C. Autologous nucleus pulposus induces neurophysiologic and histologic changes in porcine cauda equina nerve roots. Spine 1993;18:1425-32.
    • (1993) Spine , vol.18 , pp. 1425-1432
    • Olmarker, K.1    Rydevik, B.2    Nordborg, C.3
  • 38
    • 0342656125 scopus 로고    scopus 로고
    • Mediation of spinal nerve injury induced tactile allodynia by descending facilitatory pathways in the dorsolateral funiculus in rats
    • Ossipov MH, Hong Sun T, Malan P Jr, et al. Mediation of spinal nerve injury induced tactile allodynia by descending facilitatory pathways in the dorsolateral funiculus in rats. Neurosci Lett 2000;290:129-32.
    • (2000) Neurosci Lett , vol.290 , pp. 129-132
    • Ossipov, M.H.1    Hong Sun, T.2    Malan P., Jr.3
  • 39
    • 0011439196 scopus 로고    scopus 로고
    • The effect of interleukin-1β, interleukin-6, and tumor necrosis factor-α on the response of dorsal root axons and dorsal root ganglion in rats
    • in press
    • Ozaktay AC, Kallari S, Cavanaugh JM, et al. The effect of interleukin-1β, interleukin-6, and tumor necrosis factor-α on the response of dorsal root axons and dorsal root ganglion in rats. Eur Spine J 2001, in press.
    • (2001) Eur Spine J
    • Ozaktay, A.C.1    Kallari, S.2    Cavanaugh, J.M.3
  • 40
    • 0026505575 scopus 로고
    • Effects of magnitude and duration of compression on spinal nerve root conduction
    • Pedowitz R, Garfin S, Massie J, et al. Effects of magnitude and duration of compression on spinal nerve root conduction. Spine 1992;17:194-9.
    • (1992) Spine , vol.17 , pp. 194-199
    • Pedowitz, R.1    Garfin, S.2    Massie, J.3
  • 41
    • 0035879078 scopus 로고    scopus 로고
    • Inhibition of neuropathic pain by selective ablation of brainstem medullary cells expressing the mu-opioid receptor
    • Porreca F, Burgess SE, Gardell LR, et al. Inhibition of neuropathic pain by selective ablation of brainstem medullary cells expressing the mu-opioid receptor. J Neurosci 2001;15:5281-8.
    • (2001) J Neurosci , vol.15 , pp. 5281-5288
    • Porreca, F.1    Burgess, S.E.2    Gardell, L.R.3
  • 42
    • 0001059602 scopus 로고    scopus 로고
    • A comparison of the potential role of the tetrodotoxin-insensitive sodium channels, PN3/SNS and NaN/SNS2, in rat models of chronic pain
    • Porreca F, Lai J, Bian D, et al. A comparison of the potential role of the tetrodotoxin-insensitive sodium channels, PN3/SNS and NaN/SNS2, in rat models of chronic pain. Proc Natl Acad Sci U S A 1999;96:7640-4.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 7640-7644
    • Porreca, F.1    Lai, J.2    Bian, D.3
  • 43
    • 0345391048 scopus 로고    scopus 로고
    • Spinal analgesic action of endomorphins in acute, inflammatory, and neutoapthic pain in rats
    • 199
    • Przewlocka B, Mika J, Labuz D, et al. Spinal analgesic action of endomorphins in acute, inflammatory, and neutoapthic pain in rats. Eur J Pharmacol 199;367:189-96.
    • Eur J Pharmacol , vol.367 , pp. 189-196
    • Przewlocka, B.1    Mika, J.2    Labuz, D.3
  • 44
    • 0036668305 scopus 로고    scopus 로고
    • Lumbar nerve root injury induces CNS neutoimmune activation and neuroinflammation in the rat: Relationship to painful tadiculopathy
    • Rutkowski MD, Winkelstein BA, Hickey WF, et al. Lumbar nerve root injury induces CNS neutoimmune activation and neuroinflammation in the rat: Relationship to painful tadiculopathy. Spine 2002;27:1604-13.
    • (2002) Spine , vol.27 , pp. 1604-1613
    • Rutkowski, M.D.1    Winkelstein, B.A.2    Hickey, W.F.3
  • 45
    • 0002180381 scopus 로고    scopus 로고
    • Etiology of sciatic pain and mechanisms of nerve root compression
    • Wiesel SW, Weinstein JN, Herkowitz H, et al, eds. Philadelphia: WB Saunders
    • Rydevik B, Hasue M, Wehling P. Etiology of sciatic pain and mechanisms of nerve root compression. In: Wiesel SW, Weinstein JN, Herkowitz H, et al, eds. The Lumbar Spine. Philadelphia: WB Saunders, 1996:123-41.
    • (1996) The Lumbar Spine , pp. 123-141
    • Rydevik, B.1    Hasue, M.2    Wehling, P.3
  • 46
    • 0025167399 scopus 로고
    • A novel behavioral model of neuropathic pain disorders produced in rats by partial sciatic nerve injury
    • Seltzer Z, Dubner R, Shir Y. A novel behavioral model of neuropathic pain disorders produced in rats by partial sciatic nerve injury. Pain 1990;43:205-18.
    • (1990) Pain , vol.43 , pp. 205-218
    • Seltzer, Z.1    Dubner, R.2    Shir, Y.3
  • 47
    • 0033571376 scopus 로고    scopus 로고
    • Interleukin-l-beta-activated expression of cyclooxygesase-2 and inducible nitric oxide synthase in primary hippocampal neuronal culture: Platelet activating factor as a preferential mediator of cyclooxygease-2 expression
    • Serou MJ, DeCoster MA, Bazan NG. Interleukin-l-beta-activated expression of cyclooxygesase-2 and inducible nitric oxide synthase in primary hippocampal neuronal culture: Platelet activating factor as a preferential mediator of cyclooxygease-2 expression. J Neurosci Res 1999;58:593-8.
    • (1999) J Neurosci Res , vol.58 , pp. 593-598
    • Serou, M.J.1    DeCoster, M.A.2    Bazan, N.G.3
  • 48
    • 0025827277 scopus 로고
    • Neurogenic hypetalgesia: Central neural correlates in responses of spinothalamic tract neurons
    • Simone DA, Sorkin LS, Oh U, et al. Neurogenic hypetalgesia: Central neural correlates in responses of spinothalamic tract neurons. J Neurophys 1991; 66:228-46.
    • (1991) J Neurophys , vol.66 , pp. 228-246
    • Simone, D.A.1    Sorkin, L.S.2    Oh, U.3
  • 49
    • 0033597968 scopus 로고    scopus 로고
    • Neutralization antibodies to interleukin-1-receptor reduce pain-associated behavior in mice with experimental neuropathy
    • Sommer C, Petrausch S, Lindenlaub T, et al. Neutralization antibodies to interleukin-1-receptor reduce pain-associated behavior in mice with experimental neuropathy. Neurosci Lett 1999;270:25-8.
    • (1999) Neurosci Lett , vol.270 , pp. 25-28
    • Sommer, C.1    Petrausch, S.2    Lindenlaub, T.3
  • 50
    • 0033391029 scopus 로고    scopus 로고
    • Mechanical and thermal hyperalgesia and ectopic neuronal discharge after chronic compression of dorsal root ganglia
    • Song XJ, Hu SJ, reenquist KW, et al. Mechanical and thermal hyperalgesia and ectopic neuronal discharge after chronic compression of dorsal root ganglia. J Neurophysiol 1999;82:3347-58.
    • (1999) J Neurophysiol , vol.82 , pp. 3347-3358
    • Song, X.J.1    Hu, S.J.2    Reenquist, K.W.3
  • 51
    • 0033917250 scopus 로고    scopus 로고
    • Epineural application of TNF elicits an acute mechanical hyperalgesia in the awake rat
    • Sorkin LS, Doom CM. Epineural application of TNF elicits an acute mechanical hyperalgesia in the awake rat. J Peripher Nerv Syst 2000;5:96-100.
    • (2000) J Peripher Nerv Syst , vol.5 , pp. 96-100
    • Sorkin, L.S.1    Doom, C.M.2
  • 52
    • 0000131049 scopus 로고    scopus 로고
    • The cytokine challenge: Methods for the detection of central cytokines in rodent models of persistent pain
    • Kruger L, ed. Boca Raton, FL: CRC Press
    • Sweitzer S, Arruda J, DeLeo J. The cytokine challenge: Methods for the detection of central cytokines in rodent models of persistent pain. In: Kruger L, ed. Methods in Pain Research. Boca Raton, FL: CRC Press, 2001:109-32.
    • (2001) Methods in Pain Research , pp. 109-132
    • Sweitzer, S.1    Arruda, J.2    DeLeo, J.3
  • 53
    • 0036228048 scopus 로고    scopus 로고
    • The differential role of spinal MHC class II and cellular adhesion molecules in inflammatory versus neuropathic pain
    • Sweitzer S, White KA, Dutta C, et al. The differential role of spinal MHC class II and cellular adhesion molecules in inflammatory versus neuropathic pain. J Neuroimmunol 2002;125:82-93.
    • (2002) J Neuroimmunol , vol.125 , pp. 82-93
    • Sweitzer, S.1    White, K.A.2    Dutta, C.3
  • 54
    • 0035063380 scopus 로고    scopus 로고
    • Mechanisms of opioid-induced pain and antinociceptive tolerance: Descending facilitation and spinal dynorphin
    • Vanderah TW, Ossipov MH, Lai J, et al. Mechanisms of opioid-induced pain and antinociceptive tolerance: Descending facilitation and spinal dynorphin. Pain 2001;92(1-2):5-9.
    • (2001) Pain , vol.92 , Issue.1-2 , pp. 5-9
    • Vanderah, T.W.1    Ossipov, M.H.2    Lai, J.3
  • 55
    • 0035282798 scopus 로고    scopus 로고
    • Pronociceptive actions of dynorphin maintain chronic neuropathic pain
    • Wang Z, Gardell LR, Ossipov MH, et al. Pronociceptive actions of dynorphin maintain chronic neuropathic pain. J Neurosci 2001;21:1779-86.
    • (2001) J Neurosci , vol.21 , pp. 1779-1786
    • Wang, Z.1    Gardell, L.R.2    Ossipov, M.H.3
  • 56
    • 0037195594 scopus 로고    scopus 로고
    • Nerve root tissue injury severity differentially modulates spinal glial activation in a rat lumbar radiculopathy model: Considerations for persistent pain
    • in press
    • Winkelstein BA, DeLeo JA. Nerve root tissue injury severity differentially modulates spinal glial activation in a rat lumbar radiculopathy model: Considerations for persistent pain. Brain Res 2002, in press.
    • (2002) Brain Res
    • Winkelstein, B.A.1    DeLeo, J.A.2
  • 57
    • 0035888084 scopus 로고    scopus 로고
    • Nerve injury proximal or distal to the DRG induces similar spinal glial activation and selective cytokine expression but differential behavioral responses to pharmacological treatment
    • Winkelstein BA, Rutkowski, MD, Sweitzer SM, et al. Nerve injury proximal or distal to the DRG induces similar spinal glial activation and selective cytokine expression but differential behavioral responses to pharmacological treatment. J Comp Neurol 2001;438:127-39.
    • (2001) J Comp Neurol , vol.438 , pp. 127-139
    • Winkelstein, B.A.1    Rutkowski, M.D.2    Sweitzer, S.M.3
  • 58
    • 0035888956 scopus 로고    scopus 로고
    • Quantification of neural tissue injury in a rat tadiculopathy model: Comparison of local deformation, behavioral outcomes, and spinal cytokine mRNA for two surgeons
    • Winkelstein BA, Rutkowski, MD, Weinstein JN, et al. Quantification of neural tissue injury in a rat tadiculopathy model: Comparison of local deformation, behavioral outcomes, and spinal cytokine mRNA for two surgeons. J Neurosci Methods 2001;111:49-57.
    • (2001) J Neurosci Methods , vol.111 , pp. 49-57
    • Winkelstein, B.A.1    Rutkowski, M.D.2    Weinstein, J.N.3
  • 59
    • 0036123303 scopus 로고    scopus 로고
    • The role of mechanical deformation in lumbar radiculopathy: An in vivo model
    • Winkelstein BA, Weinstein JN, DeLeo JA. The role of mechanical deformation in lumbar radiculopathy: An in vivo model. Spine 2002;27:27-33.
    • (2002) Spine , vol.27 , pp. 27-33
    • Winkelstein, B.A.1    Weinstein, J.N.2    DeLeo, J.A.3
  • 60
    • 0011444440 scopus 로고    scopus 로고
    • Role of local biomechanics in temporal behavioral responses of painful radiculopathy
    • Calgary, Canada; August
    • Winkelstein BA, Weinstein JN, DeLeo JA. Role of local biomechanics in temporal behavioral responses of painful radiculopathy. Presented at the Fourth World Congress of Biomechanics; Calgary, Canada; August 2002; 5057.
    • (2002) Fourth World Congress of Biomechanics , pp. 5057
    • Winkelstein, B.A.1    Weinstein, J.N.2    DeLeo, J.A.3
  • 61
    • 0021014399 scopus 로고
    • Evidence for a central component of postinjury pain hypersensitivity
    • Woolf CJ. Evidence for a central component of postinjury pain hypersensitivity. Nature 1983;306:686-8.
    • (1983) Nature , vol.306 , pp. 686-688
    • Woolf, C.J.1
  • 62
    • 0002710594 scopus 로고
    • Behavioral investigations of pain in animals
    • Duncan IJH, Molony Y, eds. Brussels: Office for Official Publications of the European Communities
    • Zimmermann M. Behavioral investigations of pain in animals. In: Duncan IJH, Molony Y, eds. Assessing Pain in Farm Animals. Brussels: Office for Official Publications of the European Communities, 1986:16-29.
    • (1986) Assessing Pain in Farm Animals , pp. 16-29
    • Zimmermann, M.1
  • 63
    • 0035840825 scopus 로고    scopus 로고
    • Pathobiology of neuropathic pain
    • Zimmermann M. Pathobiology of neuropathic pain. Eut J Pharmacol 2001; 429:23-37.
    • (2001) Eut J Pharmacol , vol.429 , pp. 23-37
    • Zimmermann, M.1


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