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Catalytic asymmetric synthesis: (a) Hodous, B. L.; Fu, G. C. J. Am. Chem. Soc. 2002, 124, 1578-1578. (b) Taggi, A. E.; Wack, H.; Hafez, A. M.; France, S.; Lectka, T. Org. Lett. 2002, 4, 627-629. (c) Magriotis, P. A. Angew. Chem. 2001, 113, 4507-4509; Angew. Chem., Int. Ed. 2001, 40, 4377-4379. (d) Taggi, A. E.; Hafez, A. M.; Wack, H.; Young, B.; Drury, W. J.; Lectka, T. J. Am. Chem. Soc. 2000, 122, 7831-7832.
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0037149044
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Catalytic asymmetric synthesis: (a) Hodous, B. L.; Fu, G. C. J. Am. Chem. Soc. 2002, 124, 1578-1578. (b) Taggi, A. E.; Wack, H.; Hafez, A. M.; France, S.; Lectka, T. Org. Lett. 2002, 4, 627-629. (c) Magriotis, P. A. Angew. Chem. 2001, 113, 4507-4509; Angew. Chem., Int. Ed. 2001, 40, 4377-4379. (d) Taggi, A. E.; Hafez, A. M.; Wack, H.; Young, B.; Drury, W. J.; Lectka, T. J. Am. Chem. Soc. 2000, 122, 7831-7832.
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Lectka, T.5
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20
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0034674972
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Catalytic asymmetric synthesis: (a) Hodous, B. L.; Fu, G. C. J. Am. Chem. Soc. 2002, 124, 1578-1578. (b) Taggi, A. E.; Wack, H.; Hafez, A. M.; France, S.; Lectka, T. Org. Lett. 2002, 4, 627-629. (c) Magriotis, P. A. Angew. Chem. 2001, 113, 4507-4509; Angew. Chem., Int. Ed. 2001, 40, 4377-4379. (d) Taggi, A. E.; Hafez, A. M.; Wack, H.; Young, B.; Drury, W. J.; Lectka, T. J. Am. Chem. Soc. 2000, 122, 7831-7832.
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Magriotis, P.A.1
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0035803825
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Catalytic asymmetric synthesis: (a) Hodous, B. L.; Fu, G. C. J. Am. Chem. Soc. 2002, 124, 1578-1578. (b) Taggi, A. E.; Wack, H.; Hafez, A. M.; France, S.; Lectka, T. Org. Lett. 2002, 4, 627-629. (c) Magriotis, P. A. Angew. Chem. 2001, 113, 4507-4509; Angew. Chem., Int. Ed. 2001, 40, 4377-4379. (d) Taggi, A. E.; Hafez, A. M.; Wack, H.; Young, B.; Drury, W. J.; Lectka, T. J. Am. Chem. Soc. 2000, 122, 7831-7832.
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22
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0034674972
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Catalytic asymmetric synthesis: (a) Hodous, B. L.; Fu, G. C. J. Am. Chem. Soc. 2002, 124, 1578-1578. (b) Taggi, A. E.; Wack, H.; Hafez, A. M.; France, S.; Lectka, T. Org. Lett. 2002, 4, 627-629. (c) Magriotis, P. A. Angew. Chem. 2001, 113, 4507-4509; Angew. Chem., Int. Ed. 2001, 40, 4377-4379. (d) Taggi, A. E.; Hafez, A. M.; Wack, H.; Young, B.; Drury, W. J.; Lectka, T. J. Am. Chem. Soc. 2000, 122, 7831-7832.
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Taggi, A.E.1
Hafez, A.M.2
Wack, H.3
Young, B.4
Drury, W.J.5
Lectka, T.6
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23
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0037166727
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Polymer-supported synthesis: (a) Delpiccolo, C. M. L.; Mata, E. G. Tetrahedron: Asymmetry 2002, 13, 905-910. (b) Meloni, M. M.; Taddei, M. Org. Lett. 2001, 3, 337-340. (c) Gordon, K. H.; Balasubramanian, S. Org. Lett. 2001, 3, 53-56. (d) Annunziata, R.; Benaglia, M.; Cinquini, M.; Cozzi, F. Chem. Eur. J. 2000, 6, 133-138. (e) Schunk, S.; Enders, D. Org. Lett. 2000, 2, 907-910. (f) Gordon, K.; Bolger, M.; Khan, N.; Balasubramanian, S. Tetrahedron Lett. 2000, 41, 8621-8625. (g) Furman, B.; Thurmer, R.; Kaluza, Z.; Lysek, R.; Voelter, W.; Chmielewski, M. Angew. Chem. 1999, 111, 1193-1195; Angew. Chem., Int. Ed. 1999, 38, 1121-1123. (h) Ruhland, B.; Bhandari, A.; Gordon, E. M.; Gallop, M. A. J. Am. Chem. Soc. 1996, 118, 253-254.
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Delpiccolo, C.M.L.1
Mata, E.G.2
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0035825754
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Polymer-supported synthesis: (a) Delpiccolo, C. M. L.; Mata, E. G. Tetrahedron: Asymmetry 2002, 13, 905-910. (b) Meloni, M. M.; Taddei, M. Org. Lett. 2001, 3, 337-340. (c) Gordon, K. H.; Balasubramanian, S. Org. Lett. 2001, 3, 53-56. (d) Annunziata, R.; Benaglia, M.; Cinquini, M.; Cozzi, F. Chem. Eur. J. 2000, 6, 133-138. (e) Schunk, S.; Enders, D. Org. Lett. 2000, 2, 907-910. (f) Gordon, K.; Bolger, M.; Khan, N.; Balasubramanian, S. Tetrahedron Lett. 2000, 41, 8621-8625. (g) Furman, B.; Thurmer, R.; Kaluza, Z.; Lysek, R.; Voelter, W.; Chmielewski, M. Angew. Chem. 1999, 111, 1193-1195; Angew. Chem., Int. Ed. 1999, 38, 1121-1123. (h) Ruhland, B.; Bhandari, A.; Gordon, E. M.; Gallop, M. A. J. Am. Chem. Soc. 1996, 118, 253-254.
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Org. Lett.
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Meloni, M.M.1
Taddei, M.2
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25
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0035843308
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Polymer-supported synthesis: (a) Delpiccolo, C. M. L.; Mata, E. G. Tetrahedron: Asymmetry 2002, 13, 905-910. (b) Meloni, M. M.; Taddei, M. Org. Lett. 2001, 3, 337-340. (c) Gordon, K. H.; Balasubramanian, S. Org. Lett. 2001, 3, 53-56. (d) Annunziata, R.; Benaglia, M.; Cinquini, M.; Cozzi, F. Chem. Eur. J. 2000, 6, 133-138. (e) Schunk, S.; Enders, D. Org. Lett. 2000, 2, 907-910. (f) Gordon, K.; Bolger, M.; Khan, N.; Balasubramanian, S. Tetrahedron Lett. 2000, 41, 8621-8625. (g) Furman, B.; Thurmer, R.; Kaluza, Z.; Lysek, R.; Voelter, W.; Chmielewski, M. Angew. Chem. 1999, 111, 1193-1195; Angew. Chem., Int. Ed. 1999, 38, 1121-1123. (h) Ruhland, B.; Bhandari, A.; Gordon, E. M.; Gallop, M. A. J. Am. Chem. Soc. 1996, 118, 253-254.
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Org. Lett.
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Gordon, K.H.1
Balasubramanian, S.2
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0033985668
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Polymer-supported synthesis: (a) Delpiccolo, C. M. L.; Mata, E. G. Tetrahedron: Asymmetry 2002, 13, 905-910. (b) Meloni, M. M.; Taddei, M. Org. Lett. 2001, 3, 337-340. (c) Gordon, K. H.; Balasubramanian, S. Org. Lett. 2001, 3, 53-56. (d) Annunziata, R.; Benaglia, M.; Cinquini, M.; Cozzi, F. Chem. Eur. J. 2000, 6, 133-138. (e) Schunk, S.; Enders, D. Org. Lett. 2000, 2, 907-910. (f) Gordon, K.; Bolger, M.; Khan, N.; Balasubramanian, S. Tetrahedron Lett. 2000, 41, 8621-8625. (g) Furman, B.; Thurmer, R.; Kaluza, Z.; Lysek, R.; Voelter, W.; Chmielewski, M. Angew. Chem. 1999, 111, 1193-1195; Angew. Chem., Int. Ed. 1999, 38, 1121-1123. (h) Ruhland, B.; Bhandari, A.; Gordon, E. M.; Gallop, M. A. J. Am. Chem. Soc. 1996, 118, 253-254.
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Annunziata, R.1
Benaglia, M.2
Cinquini, M.3
Cozzi, F.4
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27
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0034611496
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Polymer-supported synthesis: (a) Delpiccolo, C. M. L.; Mata, E. G. Tetrahedron: Asymmetry 2002, 13, 905-910. (b) Meloni, M. M.; Taddei, M. Org. Lett. 2001, 3, 337-340. (c) Gordon, K. H.; Balasubramanian, S. Org. Lett. 2001, 3, 53-56. (d) Annunziata, R.; Benaglia, M.; Cinquini, M.; Cozzi, F. Chem. Eur. J. 2000, 6, 133-138. (e) Schunk, S.; Enders, D. Org. Lett. 2000, 2, 907-910. (f) Gordon, K.; Bolger, M.; Khan, N.; Balasubramanian, S. Tetrahedron Lett. 2000, 41, 8621-8625. (g) Furman, B.; Thurmer, R.; Kaluza, Z.; Lysek, R.; Voelter, W.; Chmielewski, M. Angew. Chem. 1999, 111, 1193-1195; Angew. Chem., Int. Ed. 1999, 38, 1121-1123. (h) Ruhland, B.; Bhandari, A.; Gordon, E. M.; Gallop, M. A. J. Am. Chem. Soc. 1996, 118, 253-254.
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Org. Lett.
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, pp. 907-910
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Schunk, S.1
Enders, D.2
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0034727307
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Polymer-supported synthesis: (a) Delpiccolo, C. M. L.; Mata, E. G. Tetrahedron: Asymmetry 2002, 13, 905-910. (b) Meloni, M. M.; Taddei, M. Org. Lett. 2001, 3, 337-340. (c) Gordon, K. H.; Balasubramanian, S. Org. Lett. 2001, 3, 53-56. (d) Annunziata, R.; Benaglia, M.; Cinquini, M.; Cozzi, F. Chem. Eur. J. 2000, 6, 133-138. (e) Schunk, S.; Enders, D. Org. Lett. 2000, 2, 907-910. (f) Gordon, K.; Bolger, M.; Khan, N.; Balasubramanian, S. Tetrahedron Lett. 2000, 41, 8621-8625. (g) Furman, B.; Thurmer, R.; Kaluza, Z.; Lysek, R.; Voelter, W.; Chmielewski, M. Angew. Chem. 1999, 111, 1193-1195; Angew. Chem., Int. Ed. 1999, 38, 1121-1123. (h) Ruhland, B.; Bhandari, A.; Gordon, E. M.; Gallop, M. A. J. Am. Chem. Soc. 1996, 118, 253-254.
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Tetrahedron Lett.
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Gordon, K.1
Bolger, M.2
Khan, N.3
Balasubramanian, S.4
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29
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0000133566
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Polymer-supported synthesis: (a) Delpiccolo, C. M. L.; Mata, E. G. Tetrahedron: Asymmetry 2002, 13, 905-910. (b) Meloni, M. M.; Taddei, M. Org. Lett. 2001, 3, 337-340. (c) Gordon, K. H.; Balasubramanian, S. Org. Lett. 2001, 3, 53-56. (d) Annunziata, R.; Benaglia, M.; Cinquini, M.; Cozzi, F. Chem. Eur. J. 2000, 6, 133-138. (e) Schunk, S.; Enders, D. Org. Lett. 2000, 2, 907-910. (f) Gordon, K.; Bolger, M.; Khan, N.; Balasubramanian, S. Tetrahedron Lett. 2000, 41, 8621-8625. (g) Furman, B.; Thurmer, R.; Kaluza, Z.; Lysek, R.; Voelter, W.; Chmielewski, M. Angew. Chem. 1999, 111, 1193-1195; Angew. Chem., Int. Ed. 1999, 38, 1121-1123. (h) Ruhland, B.; Bhandari, A.; Gordon, E. M.; Gallop, M. A. J. Am. Chem. Soc. 1996, 118, 253-254.
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Furman, B.1
Thurmer, R.2
Kaluza, Z.3
Lysek, R.4
Voelter, W.5
Chmielewski, M.6
-
30
-
-
0033583509
-
-
Polymer-supported synthesis: (a) Delpiccolo, C. M. L.; Mata, E. G. Tetrahedron: Asymmetry 2002, 13, 905-910. (b) Meloni, M. M.; Taddei, M. Org. Lett. 2001, 3, 337-340. (c) Gordon, K. H.; Balasubramanian, S. Org. Lett. 2001, 3, 53-56. (d) Annunziata, R.; Benaglia, M.; Cinquini, M.; Cozzi, F. Chem. Eur. J. 2000, 6, 133-138. (e) Schunk, S.; Enders, D. Org. Lett. 2000, 2, 907-910. (f) Gordon, K.; Bolger, M.; Khan, N.; Balasubramanian, S. Tetrahedron Lett. 2000, 41, 8621-8625. (g) Furman, B.; Thurmer, R.; Kaluza, Z.; Lysek, R.; Voelter, W.; Chmielewski, M. Angew. Chem. 1999, 111, 1193-1195; Angew. Chem., Int. Ed. 1999, 38, 1121-1123. (h) Ruhland, B.; Bhandari, A.; Gordon, E. M.; Gallop, M. A. J. Am. Chem. Soc. 1996, 118, 253-254.
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Polymer-supported synthesis: (a) Delpiccolo, C. M. L.; Mata, E. G. Tetrahedron: Asymmetry 2002, 13, 905-910. (b) Meloni, M. M.; Taddei, M. Org. Lett. 2001, 3, 337-340. (c) Gordon, K. H.; Balasubramanian, S. Org. Lett. 2001, 3, 53-56. (d) Annunziata, R.; Benaglia, M.; Cinquini, M.; Cozzi, F. Chem. Eur. J. 2000, 6, 133-138. (e) Schunk, S.; Enders, D. Org. Lett. 2000, 2, 907-910. (f) Gordon, K.; Bolger, M.; Khan, N.; Balasubramanian, S. Tetrahedron Lett. 2000, 41, 8621-8625. (g) Furman, B.; Thurmer, R.; Kaluza, Z.; Lysek, R.; Voelter, W.; Chmielewski, M. Angew. Chem. 1999, 111, 1193-1195; Angew. Chem., Int. Ed. 1999, 38, 1121-1123. (h) Ruhland, B.; Bhandari, A.; Gordon, E. M.; Gallop, M. A. J. Am. Chem. Soc. 1996, 118, 253-254.
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1,4-Bisaryl β-lactams: see ref 11. 4-Oxo- and 4-thioxo-substituted β-lactams: (a) Cainelli, G.; Gaicomini, D.; Panunzio, M.; Martelli, G.; Spunta, G. Tetrahedron Lett. 1987, 28, 3593-3596. (b) Battaglia, A.; Cainelli, G.; Giacomini, D.; Martelli, G.; Panunzio, M. Tetrahedron Lett. 1987, 28, 4347-4350. N-Unsubstituted β-lactams: (c) Hart, D. J.; Kanai, K.-I.; Thomas, D. G.; Yang, T. -K. J. Org. Chem. 1983, 48, 289-294. (d) Ha, D.-C.; Hart, D. J.; Yang, T.-K. J. Am. Chem. Soc. 1984, 106, 4819-4825. 4-Unsubstituted β-lactams: (e) Overman, L. E.; Osawa, T. J. Am. Chem. Soc. 1985, 107, 1698-1701.
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Reaction conditions were not optimized.
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Low yields of α-unsubstituted esters in ester-enolate imine condensation reactions have been described in the literature, see e.g., ref 11a.
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