Inhibition of human leukocyte elastase by functionalized N-aryl-3,3-dihalogenoazetidin-2-ones. Stereospecific synthesis and chiral recognition of dissymmetrically C3-snbstituted β-lactams

Tetrahedron Asymmetry

Volumn 8, Issue 5, 1997, Pages 739-751

  Doucet, Caroline ^a   Vergely, Isabelle ^a   Reboud Ravaux, Michèle ^a   Guilhem, Jean ^b   Kobaiter, Randa ^c   Joyeau, Roger ^d   Wakselman, Michel ^c  

^a INSTITUT JACQUES MONOD   (France)

^b INSTITUT DE CHIMIE DES SUBSTANCES NATURELLES   (France)

^c LABORATOIRE DES SCIENCES DU CLIMAT ET DE L ENVIRONNEMENT   (France)

^d MUSÉUM NATIONAL D'HISTOIRE NATURELLE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

2 AZETIDINONE DERIVATIVE; BETA LACTAM DERIVATIVE; ELASTASE; ELASTASE INHIBITOR;

ARTICLE; DIASTEREOISOMER; DRUG PURIFICATION; DRUG SYNTHESIS; ENANTIOMER; ENZYME INHIBITION; LEUKOCYTE; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; X RAY DIFFRACTION;

EID: 0031051016     PISSN: 09574166     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0957-4166(97)00017-7     Document Type: Article

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