Cytochrome P4502e1- and cytochrome P4502b1/2b2-catalyzed carbon tetrachloride metabolism: Effects on signal transduction as demonstrated by altered immediate-early (c-fos and c-jun) gene expression and nuclear AP-1 and NF-κB transcription factor levels

Drug Metabolism and Disposition

Volumn 24, Issue 1, 1996, Pages 15-22

  Gruebele, Andrea ^a   Zawaski, Kimberly ^a   Kaplan, David ^a   Novak, Raymond F ^a  

^a WAYNE STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ALLYL SULFIDE; CARBON TETRACHLORIDE; COMPLEMENTARY DNA; CYTOCHROME P450 ISOENZYME; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; PHENOBARBITAL; POLYADENYLATED RNA; PYRIDINE; TRANSCRIPTION FACTOR; XENOBIOTIC AGENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CATALYSIS; CONTROLLED STUDY; GENE EXPRESSION; IMMEDIATE EARLY GENE; INTRAPERITONEAL DRUG ADMINISTRATION; LIVER; MALE; NONHUMAN; ONCOGENE C FOS; ONCOGENE C JUN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; XENOBIOTIC METABOLISM;

ANIMALS; BASE SEQUENCE; CARBON TETRACHLORIDE; CATALYSIS; CELL NUCLEUS; CYTOCHROME P-450 ENZYME SYSTEM; DNA PRIMERS; ENZYME INDUCTION; GENE EXPRESSION; GENES, FOS; GENES, JUN; ISOENZYMES; LIVER; MALE; MOLECULAR SEQUENCE DATA; NF-KAPPA B; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1;

ANIMALIA;

EID: 0030068202     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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