Enhancement by antisense oligonucleotides to NF-kB of the differentiation of HL-60 promyelocytic leukemia cells induced by vitamin D3

Cancer Letters

Volumn 125, Issue 1-2, 1998, Pages 157-164

  Sokoloski, John A ^a   Narayanan, Ramaswamy ^b   Sartorelli, Alan C ^a  

^a YALE CANCER CENTER   (United States)

^b HOFFMANN LA ROCHE INC   (United States)

Author keywords

Differentiation; Hl 60 leukemia; NF kB; Phosphorothioate antisense oligomers; Transcription factor decoys; Vitamin D3

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; COLECALCIFEROL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; OLIGODEOXYNUCLEOTIDE PHOSPHOROTHIOATE;

ARTICLE; CELL DIFFERENTIATION; CELL MATURATION; CELL STRAIN HL 60; CONSENSUS SEQUENCE; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

CELL DIFFERENTIATION; CHOLECALCIFEROL; DIMETHYL SULFOXIDE; DNA; HL-60 CELLS; HUMANS; NF-KAPPA B; OLIGONUCLEOTIDES, ANTISENSE; TRANSCRIPTION FACTOR RELA;

EID: 0032513170     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(97)00505-3     Document Type: Article

References (41)

1. Nabel G., Baltimore D. An inducible transcriptional factor activates expression of the human immunodeficiency virus in T cells. Nature. 335:1987;683-689.
2. Baeuerle P.A., Baltimore D. The physiology of the NF-kappa-B transcription factor. Mol. Aspects Cell. Regul. 6:1991;409-432.
3. Grilli M., Chiu J.J.-S., Lenardo M.J. NF-kB and rel: participants in a multiform regulatory system. Int. Rev. Cytol. 148:1993;1-63.
4. Lenardo M.J., Baltimore D. NF-kB: a pleiotropic mediator of inducible and tissue-specific gene control. Cell. 58:1989;227-229.
5. Baeuerle P.A., Henkel T. Function and activation of NF-kB in the immune system. Annu. Rev. Immunol. 12:1994;141-179.
6. Kunsch C., Ruben S.M., Rosen C.A. Selection of optimal kB/rel DNA binding motifs: interaction of both subunits of NF-kB with DNA is required for transcriptional activation. Mol. Cell. Biol. 12:1992;4412-4421.
7. Bose H.R. The rel family: models for transcriptional regulation and oncogenic transformation. Biochim. Biophys. Acta. 1114:1992;1-17.
8. Gilmore T.D. Role of rel family genes in normal and malignant lymphoid cell growth. Cancer Surv. 15:1992;69-87.
9. N.R. Rice, R.V. Gilden, The rel oncogene, in: E.P. Reddy (Ed.), The Oncogene Handbook, Elsevier, New York, 1988, pp. 495-512.
10. Steward R. Dorsal, an embryonic polarity gene in Drosophila is homologous to the vertebrate proto-oncogene, c-rel. Science. 238:1987;692-694.
11. Baeuerle P.A., Baltimore D. IkB: a specific inhibitor of the NFkB transcription factor. Science. 242:1988;540-546.
12. Baeuerle P.A., Baltimore D. Activation of DNA binding activity in an apparently cytoplasmic precursor of the NF-kB transcription factor. Cell. 53:1988;211-217.
13. Schreck R., Baeuerle P.A. NF-kB as inducible transcriptional activator of the granulocyte-macrophage colony-stimulating factor gene. Mol. Cell. Biol. 10:1990;1281-1286.
14. Sokoloski J.A., Sartorelli A.C., Rosen C.A., Narayanan R. Antisense oligonucleotides to the p65 subunit of NF-kB block CD11b expression and alter adhesion properties of differentiated HL-60 granulocytes. Blood. 82:1993;625-632.
15. 3: relationship to NF-kB, Leukemia 11 (1997) 1546-1553.
16. 3: relationship to NF-kB. Oncol. Res. 9:1997;31-39.
17. 3, Leukemia Res. (1998), in press.
18. 3-induced differentiation in human promyelocytic leukemia HL-60 cells. Oncol. Res. 9:1997;19-29.
19. Bunce C.M., Mountford J.C., French P.J., Mole D.J., Durham R.H., Brown G. Potentiation of myeloid differentiation by anti-inflammatory agents, by steroids and by retinoic acid involves a single intracellular target, probably an enzyme of the aldoketoreductase family. Biochim. Biophys. Acta. 1311:1996;189-198.
20. Suzuki Y., Packer L. Inhibition of NF-kB activation by vitamin E derivatives. Biochem. Biophys. Res. Commun. 193:1993;277-283.
21. Suzuki Y., Aggarwal B.B., Packer L. α-Lipoic acid is a potent inhibitor of NF-kB activation in human T cells. Biochem. Biophys. Res. Commun. 189:1992;1709-1715.
22. Chan M.M.-Y. Inhibition of tumor necrosis factor by curcumin, a phytochemical. Biochem. Pharmacol. 49:1995;1551-1556.
23. Kopp E., Ghosh S. Inhibition of NF-kB by sodium salicylate and aspirin. Science. 265:1994;956-959.
24. Weber C., Erl W., Pietsch A., Weber P.C. Aspirin inhibits nuclear factor-kB mobilization and monocyte adhesion in stimulated human endothelial cells. Circulation. 91:1995;1914-1917.
25. Reiss M., Gamba-Vitalo C., Sartorelli A.C. Induction of tumor cell differentiation as a therapeutic approach: preclinical models for hematopoietic and solid neoplasms. Cancer Treat. Rep. 70:1986;201-217.
26. Higgins K.A., Perez J.R., Coleman T.A., Dorshkind K., McComas W.A., Sarmiento U.M., Rosen C.A., Narayanan R. Antisense inhibition of the p65 subunit of NF-kB blocks tumorgenicity and causes tumor regression. Proc. Natl. Acad. Sci. USA. 90:1993;9901-9905.
27. Narayanan R., Higgins K.A., Coleman T.A., Lawlor K.G., Rosen C.A. Evidence for differential functions of the p50 and p65 subunits of NF-kB using a cell adhesion model. Mol. Cell. Biol. 13:1993;3802-3810.
28. Sharma H.W., Perez J.R., Higgins-Sochaski K., Hsiao R., Narayanan R. Transcription factor decoy approach to decipher the role of NF-kB in oncogenesis. Anticancer Res. 16:1996;61-70.
29. Oeth P.A., Parry G.C.N., Kunsch C., Nantermet P., Rosen C.A., Mackman N. Lipopolysaccharide induction of tissue factor gene expression in monocytic cells is mediated by binding of c-rel/p65 heterodimers to a kB-like site. Mol. Cell. Biol. 14:1994;3772-3781.
30. Sharma H.W., Higgins-Sochaski K., Perez J.R., Narayanan R. A DNA motif present in a αV integrin promoter exhibits dual binding preference to distinct transcription factors. Anticancer Res. 15:1995;1857-1868.
31. Dunn S.M., Coles L.S., Lang R.K., Gerondakas S., Vadas M.A., Shannon M.F. Requirements for nuclear factor (NF)-kB p65 and NF-interleukin-6 binding elements in the tumor necrosis factor response region of the granulocyte colony-stimulating factor promoter. Blood. 83:1994;2469-2479.
32. Shannon M.F., Pell L.M., Lenardo M.J., Kuczek E.S., Occhiodoro F.S., Dunn S.M., Vadas M.A. A novel tumor necrosis factor-responsive transcription factor which recognizes a regulatory element in hematopoietic growth factor genes. Mol. Cell. Biol. 10:1990;2950-2959.
33. Bours V., Dejardin E., Goujon-Letawe F., Merville M.-P., Castronovo V. The NF-kB transcription factor and cancer: high expression of NF-kB and IkB-related proteins in tumor cell lines. Biochem. Pharmacol. 47:1994;145-149.
34. Sharma H.W., Narayanan R. The NF-kB transcription factor in oncogenesis. Anticancer Res. 16:1996;589-596.
35. Kitajima I., Shinohara T., Bilakovics J., Brown D.A., Xu X., Nerenberg M. Ablation of transplanted HTLV-I tax-transformed tumors in mice by antisense inhibition of NF-kB. Science. 258:1992;1792-1795.
36. Perez J.R., Higgins-Sochaski K.A., Maltese J.Y., Narayanan R. Regulation of adhesion and growth of fibrosarcoma cells by NF-kB Rel A involves transforming growth factor β Mol. Cell. Biol. 14:1994;5326-5332.
37. Voraberger G., Schafer R., Stratowa C. Cloning of the human gene for intracellular adhesion molecule I and analysis of its 5′ regulatory region: induction by cytokines and phorbol ester. J. Immunol. 147:1991;2777-2786.
38. Lilienbaum A., DucDoden M., Alexandre C., Gazzolo L., Paulin D. Effect of human T-cell virus type I Tax protein on activation of the human vimentin gene. J. Virol. 64:1990;256-263.
39. Whelan J., Ghersa P., vanHuijsduijnen R.H., Gray J., Chandra G., Talabot F., DeLamorter J.F. An NF-kB like factor is essential but not sufficient for cytokine induction of endothelial leukocyte adhesion molecule I (ELAM-1) gene transcription. Nucleic Acids Res. 19:1991;2645-2653.
40. Eck S.L., Perkins N.D., Carr D.P., Nabel G.J. Inhibition of phorbol ester-induced cellular adhesion by competitive binding of NF-kB in vivo. Mol. Cell. Biol. 13:1993;6530-6536.
41. Pugh B.F., Tijan R. Mechanism of transcriptional activation by Sp1: evidence for coactivators. Cell. 61:1990;1187-1197.