Molecular mechanism of a COOH-terminal gating determinant in the ROMK channel revealed by a Bartter's disease mutation

Journal of Physiology

Volumn 544, Issue 2, 2002, Pages 351-362

  Flagg, Thomas P ^c   Yoo, Dana ^c   Sciortino, Christopher M ^b   Tate, Margaret ^a   Romero, Michael F ^b   Welling, Paul A ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; BACTERIAL PROTEIN; CARBOXYL GROUP; HYBRID PROTEIN; INWARDLY RECTIFYING POTASSIUM CHANNEL; PEPTIDE; PROTEIN SUBUNIT; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR1.1; UNCLASSIFIED DRUG;

ALKALINITY; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BARTTER SYNDROME; BINDING ASSAY; CARBOXY TERMINAL SEQUENCE; CHANNEL GATING; CONTROLLED STUDY; FEMALE; GENE MUTATION; IN VITRO STUDY; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; REGULATORY MECHANISM; TRANS ISOMER; CELL PH; CYTOPLASM; DISEASE ASSOCIATION; GENE DELETION; LOSS OF FUNCTION MUTATION; METABOLIC REGULATION; MOLECULAR INTERACTION; OOCYTE; XENOPUS LAEVIS;

AMINO ACID SEQUENCE; ANIMALS; BARTTER SYNDROME; CYTOPLASM; FEMALE; GENES, SUPPRESSOR; HUMANS; HYDROGEN-ION CONCENTRATION; INTRACELLULAR MEMBRANES; ION CHANNEL GATING; MUTATION; OOCYTES; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROTEIN STRUCTURE, TERTIARY; REFERENCE VALUES; XENOPUS LAEVIS;

EID: 0037107407     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.2002.027581     Document Type: Article

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