pH-dependent gating of ROMK (K(ir)1.1) channels involves conformational changes in both N and C termini

Journal of Biological Chemistry

Volumn 273, Issue 51, 1998, Pages 34575-34579

  Schulte, Uwe ^a   Hahn, Hartmut ^a   Wiesinger, Heinrich ^b   Peter Ruppersberg, J ^a   Fakler, Bernd ^a  

^a Department of Physiology II ^*  (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

1,10 PHENANTHROLINE COPPER; 5,5' DITHIOBIS(2 NITROBENZOIC ACID); CYSTEINE; DITHIOTHREITOL; LYSINE; OXIDIZING AGENT; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; POTASSIUM CHANNEL; POTASSIUM ION; THIOL REAGENT;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL PH; CHANNEL GATING; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN DOMAIN; SITE DIRECTED MUTAGENESIS; XENOPUS;

AMINO ACID SUBSTITUTION; ANIMALS; CYSTEINE; DITHIONITROBENZOIC ACID; DITHIOTHREITOL; FEMALE; HYDROGEN-ION CONCENTRATION; ION CHANNEL GATING; KIDNEY; MEMBRANE POTENTIALS; MUTAGENESIS, SITE-DIRECTED; OOCYTES; OXIDATION-REDUCTION; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; XENOPUS LAEVIS;

EID: 0032545369     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.51.34575     Document Type: Article

References (20)

1. Wang, W., Schwab, A., and Giebisch, G. (1990) Am. J. Physiol 259, F494-F502
2. Wang, W., Sackin, H., and Giebisch, G. (1992) Annu. Rev. Physiol. 54, 81-96
3. Wright, F. S., and Giebisch, G. (1992) in The Kidney: Physiology and Pathophysiology (Seidin, D. W., and Giebisch, G., eds) pp. 2209-2248, Raven Press, Ltd., New York
4. Ho, K., Nichols, C. G., Lederer, W. J., Lytton, J., Vassilev, P. M., Kanazirska, M. V., and Hebert, S. C. (1993) Nature 362, 31-38
5. Boim, M. A., Ho, K., Shuck, M. E., Bienkowski, M. J., Block, J. H., Slightom, J. L., Yang, Y., Brenner, B. M., and Hebert, S. C. (1995) Am. J. Physiol. 268, F1132-F1140
6. Zhou, H., Tate, S. S., and Palmer, L. G. (1994) Am. J. Physiol. 263, C809-C824
7. Doupnik, C. A., Davidson, N., and Lester, H. A. (1995) Curr. Opin. Neurobiol. 5, 268-277
8. Fakler, B., and Ruppersberg, J. P. (1996) Cell Physiol. Biochem. 6, 195-209
9. Nichols, C., and Lopatin, A. (1997) Annu. Rev. Physiol. 59, 171-191
10. Kubo, Y., Baldwin, T. J., Jan, Y. N., and Jan, L. Y. (1993) Nature 362, 127-133
11. Glowatzki, E., Fakler, G., Brändle, U., Rexhausen, U., Zenner, H. P., Ruppersberg, J. P., and Fakler, B. (1995) Proc. R. Soc. Land. B Biol. Sci. 261, 251-261
12. Yang, J., Jan, Y. N., and Jan, L. Y. (1995) Neuron 15, 1441-1447
13. Krapivinsky, G., Gordon, E. A., Wickman, K., Velimirovic, B., Krapivinsky, L., and Clapham, D. E. (1995) Nature 374, 135-141
14. Fakler, B., Brändle, U., Glowatzki, E., König, C., Bond, C., Adelman, J. P., Zenner, H.-P., and Ruppersberg, J. P. (1994) FEBS Lett. 356, 199-203
15. Ficker, E., Taglialatela, M., Wible, B. A., Henley, C. M., and Brown, A. M. (1994) Science 266, 1068-1072
16. Lopatin, A. N., Makhina, E. H., and Nichols, C. G. (1994) Nature 372, 366-369
17. Fakler, B., Brändle, U., Glowatzki, E., Weidemann, S., Zenner, H. P., and Ruppersberg, J. P. (1995) Cell 80, 149-154
18. Lee, W.-S., and Hebert, S. (1995) Am. J. Physiol. 268, F1124-F1131
19. Fakler, B., Schultz, J. H., Yang, J., Schulte, U., Brändle, U., Zenner, H. P., Jan, L. Y., and Ruppersberg, J. P. (1996) EMBO J. 15, 4093-4099
20. Tsai, T. D., Shuck, M. E., Thompson, D. P., Bienkowski, M. J., and Lee, K. S. (1995) Am. J. Physiol. 37, C1173-C1178