Dual role of Lys206-Lys296 interaction in human transferrin N-lobe: Iron-release trigger and anion-binding site

Biochemistry

Volumn 38, Issue 30, 1999, Pages 9704-9711

  He, Qing Yu ^a   Mason, Anne B ^a   Tam, Beatrice M ^b   MacGillivray, Ross T A ^b   Woodworth, Robert C ^a  

^a UNIVERSITY OF VERMONT   (United States)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANION; CHLORIDE ION; GLUTAMIC ACID; GLUTAMINE; IRON; LYSINE; SULFATE; TRANSFERRIN; TYROSINE;

ACIDITY; AMINO ACID SUBSTITUTION; ARTICLE; BINDING SITE; CHELATION; CONCENTRATION RESPONSE; HYDROGEN BOND; IRON KINETICS; IRON TRANSPORT; MOLECULAR DYNAMICS; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN TERTIARY STRUCTURE; PROTON TRANSPORT; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; SURFACE CHARGE;

ANIMALS; ANIONS; BINDING SITES; CELL LINE; CHLORIDES; CRICETINAE; FERRIC COMPOUNDS; HUMANS; HYDROGEN-ION CONCENTRATION; KINETICS; LYSINE; MODELS, MOLECULAR; PEPTIDE FRAGMENTS; SPECTROPHOTOMETRY, ULTRAVIOLET; SULFATES; TRANSFERRIN;

EID: 0033609501     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi990134t     Document Type: Article

References (32)

1. Griffiths, E. (1987) in Iron and Infection (Bullen, J. J., and Griffiths, E., Eds.) pp 1-25, John Wiley & Sons, Chichester.
2. Chasteen, N. D., and Woodworth, R. C. (1990) in Iron Transport and Storage (Ponka, P., Schulman, H. M., and Woodworth, R. C., Eds.) pp 67-79, CRC Press, Boca Raton, FL.
3. Baker, E. N. (1994) Adv. Inorg. Chem. 41, 389-463.
4. Anderson, B. F., Baker, H. M., Dodson, E. J., Norris, G. E., Rumball, S. V., Waters, J. M., and Baker, E. N. (1987) Proc. Natl. Acad. Sci. U.S.A. 84, 1769-1773.
5. Bailey, S., Evans, R. W., Garratt, R. C., Gorinsky, B., Hasnain, S. S., Horsburgh, C., Jhoti, H., Lindley, P. F., Mydin, A., Sarra, R., and Watson, J. L. (1988) Biochemistry 27, 5804-5812.
6. Kurokawa, H., Mikami, B., and Hirose, M. (1995) J. Mol. Biol. 254, 196-207.
7. Zuccola, H. J. (1993) The crystal structure of monoferric human serum transferrin, Thesis/Dissertation, Georgia Institute of Technology, Atlanta, GA.
8. MacGillivray, R. T. A., Moore, S. A., Chen, J., Anderson, B. F., Baker, H., Luo, Y., Bewley, M., Smith, C. A., Murphy, M. E. P., Wang, Y., Mason, A. B., Woodworth, R. C., Brayer, G. D., and Baker, E. N. (1998) Biochemistry 37, 7919-7928.
9. Jeffrey, P. D., Bewley, M. C., MacGillivray, R. T. A., Mason, A. B., Woodworth, R. C., and Baker, E. N. (1998) Biochemistry 37, 13978-13986.
10. Dewan, J. C., Mikami, B., Hirose, M., and Sacchettini, J. C. (1993) Biochemistry 32, 11963-11968.
11. Baker, E. N. and Lindley, P. F. (1992) J. Inorg. Biochem. 47, 147-160.
12. Egan, T. J., Ross, D. C., and Purves, L. R. (1994) S. Afr. J. Sci. 90, 539-543.
13. Lindley, P. F., Bajaj, M., Evans, R. W., Garratt, R. C., Hasnain, S. S., Jhoti, H., Kuser, P., Neu, M., Patel, K., Sarra, R., Strange, R., and Walton, A. (1993) Acta Crystallogr., Sect. D 49, 292-304.
14. Cheng, Y. G., Mason, A. B., and Woodworth, R. C. (1995) Biochemistry 34, 14879-14884.
15. Li, Y., Harris, W. R., Maxwell, A., MacGillivray, R. T. A., and Brown, T. (1998) Biochemistry 37, 14157-14166.
16. Nelson, R. M., and Long, G. L. (1989) Anal. Biochem. 180, 147-151.
17. Funk, W. D., MacGillivray, R. T. A., Mason, A. B., Brown, S. A., and Woodworth, R. C. (1990) Biochemistry 29, 1654-1660.
18. He, Q.-Y., Mason, A. B., Woodworth, R. C., Tam, B. M., Wadsworth, T., and MacGillivray, R. T. A. (1997) Biochemistry 36, 5522-5528.
19. Woodworth, R. C., Mason, A. B., Funk, W. D., and MacGillivray, R. T. A. (1991) Biochemistry 30, 10824-10829.
20. Mason, A. B., Funk, W. D., MacGillivray, R. T. A., and Woodworth, R. C. (1991) Protein Expression Purif. 2, 214-220.
21. He, Q.-Y., Mason, A. B., and Woodworth, R. C. (1997) Biochem. J. 328, 439-445.
22. He, Q.-Y., Mason, A. B., Woodworth, R. C., Tam, B. M., MacGillivray, R. T. A., Grady, J. K., and Chasteen, N. D. (1997) Biochemistry 36, 14853-14860.
23. Harris, W. R. (1985) Biochemistry 24, 7412-7418.
24. Harris, W. R., Cafferty, A. M., Abdollahi, S., and Trankler, K. (1998) Biochim. Biophys. Acta 1383, 197-210.
25. He, Q.-Y., Mason, A. B., Woodworth, R. C., Tam, B. M., MacGillivray, R. T. A., Grady, J. K., and Chasteen, N. D. (1998) J. Biol. Chem. 273, 17018-17024.
26. Gerstein, M., Anderson, B. F., Norris, G. E., Baker, E. N., Lesk, A. M., and Chothia, C. (1993) J. Mol. Biol. 234, 357-372.
27. Chasteen, N. D., and Williams, J. (1981) Biochem. J. 193, 717-727.
28. Foley, A. A., and Bates, G. W. (1988) Biochim. Biophys. Acta 965, 154-162.
29. Grady, J. K., Mason, A. B., Woodworth, R. C., and Chasteen, N. D. (1995) Biochem. J. 309, 403-410.
30. Zak, O., Tam, B., MacGillivray, R. T., and Aisen, P. (1997) Biochemistry 36, 11036-11043.
31. Kraulis, P. (1991) J. Appl. Crystallogr. 24, 946-950.
32. Merritt, E. A., and Murphy, M. E. P. (1994) Acta Crystallogr., Sect. D 50, 869-873.