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Volumn 114, Issue 5, 1999, Pages 685-700

A mutation linked with Bartter's syndrome locks Kir 1.1a (ROMK1) channels in a closed state

Author keywords

Channel; Gate; Green fluorescent protein; Potassium; Subunit oligomerization

Indexed keywords

GREEN FLUORESCENT PROTEIN;

EID: 0032717278     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.114.5.685     Document Type: Article
Times cited : (44)

References (55)
  • 2
    • 50849151835 scopus 로고
    • Hyperplasia of the juxtaglomerular complex with hyperaldosteronism and hypokalemic alkalosis: A new syndrome
    • Bartter, F.C., P. Pronove, J.R. Gill, Jr., and R.C. MacCardle. 1962. Hyperplasia of the juxtaglomerular complex with hyperaldosteronism and hypokalemic alkalosis: a new syndrome. Am. J. Med. 33:811-828.
    • (1962) Am. J. Med. , vol.33 , pp. 811-828
    • Bartter, F.C.1    Pronove, P.2    Gill J.R., Jr.3    MacCardle, R.C.4
  • 5
    • 0030664037 scopus 로고    scopus 로고
    • A conserved cytoplasmic region of ROMK modulates pH sensitivity, conductance and gating
    • Choe, H., H. Zhou, L.G. Palmer, and H. Sackin. 1997. A conserved cytoplasmic region of ROMK modulates pH sensitivity, conductance and gating. Am. J. Physiol. 273:F516-F529.
    • (1997) Am. J. Physiol. , vol.273
    • Choe, H.1    Zhou, H.2    Palmer, L.G.3    Sackin, H.4
  • 6
    • 0031688597 scopus 로고    scopus 로고
    • Permeation and gating of an inwardly rectifying potassium channel: Evidence for a variable energy well
    • Choe, H., H. Sackin, and L.G. Palmer. 1998. Permeation and gating of an inwardly rectifying potassium channel: evidence for a variable energy well. J. Gen. Physiol. 112:433-446.
    • (1998) J. Gen. Physiol. , vol.112 , pp. 433-446
    • Choe, H.1    Sackin, H.2    Palmer, L.G.3
  • 7
    • 0029973636 scopus 로고    scopus 로고
    • FACS-optimized mutants of the green fluorescent protein (GFP)
    • Cormack, B.P., R.H. Valdivia, and S. Falkow. 1996. FACS-optimized mutants of the green fluorescent protein (GFP). Gene. 173:33-38.
    • (1996) Gene. , vol.173 , pp. 33-38
    • Cormack, B.P.1    Valdivia, R.H.2    Falkow, S.3
  • 9
    • 15144353151 scopus 로고    scopus 로고
    • A hyperprostaglandin E syndrome mutation in Kir 1.1 (renal outer medullary potassium) channels reveals a crucial residue for channel function in Kir 1.3 channels
    • Deist, C., E. Wischmeyer, R. Preisig-Muller, A. Spauschus, M. Konrad, P. Hensen, N. Jeck, H.W. Seyberth, J. Daut, and A. Karschin. 1998. A hyperprostaglandin E syndrome mutation in Kir 1.1 (renal outer medullary potassium) channels reveals a crucial residue for channel function in Kir 1.3 channels. J. Biol. Chem. 273: 23884-23891.
    • (1998) J. Biol. Chem. , vol.273 , pp. 23884-23891
    • Deist, C.1    Wischmeyer, E.2    Preisig-Muller, R.3    Spauschus, A.4    Konrad, M.5    Hensen, P.6    Jeck, N.7    Seyberth, H.W.8    Daut, J.9    Karschin, A.10
  • 10
    • 0032505868 scopus 로고    scopus 로고
    • XTP, channel inhibition of ATP requires distinct functional domains of the cytoplasmic C terminus of the pore-forming subunit
    • XTP, channel inhibition of ATP requires distinct functional domains of the cytoplasmic C terminus of the pore-forming subunit. Proc. Natl. Acad. Sci. USA. 95: 13953-13958.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 13953-13958
    • Drain, P.1    Li, L.2    Wang, J.3
  • 12
    • 0030451774 scopus 로고    scopus 로고
    • Cell surface expression of the epithelial Na channel and a mutant causing Liddle syndrome: A quantitative approach
    • Firsov, D., L. Schild, I. Gautschi, A.M. Merillat, E. Schneeberger, and B.C. Rossier. 1996. Cell surface expression of the epithelial Na channel and a mutant causing Liddle syndrome: a quantitative approach. Proc. Natl. Acad. Sci. USA. 93:15370-15375.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 15370-15375
    • Firsov, D.1    Schild, L.2    Gautschi, I.3    Merillat, A.M.4    Schneeberger, E.5    Rossier, B.C.6
  • 13
    • 0024552339 scopus 로고
    • Low-conductance K channels in apical membrane of rat cortical collecting tubule
    • Frindt, G., and L.G. Palmer. 1989. Low-conductance K channels in apical membrane of rat cortical collecting tubule. Am. J. Physiol. 256:F143-F151.
    • (1989) Am. J. Physiol. , vol.256
    • Frindt, G.1    Palmer, L.G.2
  • 14
    • 0031831767 scopus 로고    scopus 로고
    • Renal potassium transport: Mechanisms and regulation
    • Giebisch, G. 1998. Renal potassium transport: mechanisms and regulation. Am. J. Physiol. 274:F817-F833.
    • (1998) Am. J. Physiol. , vol.274
    • Giebisch, G.1
  • 16
    • 0032144244 scopus 로고    scopus 로고
    • Bartter syndrome: Unraveling the pathophysiologic enigma
    • Guay-Woodford, L.M. 1998. Bartter syndrome: unraveling the pathophysiologic enigma. Am. J. Med. 105:151-161.
    • (1998) Am. J. Med. , vol.105 , pp. 151-161
    • Guay-Woodford, L.M.1
  • 17
    • 0019441262 scopus 로고
    • Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
    • Hamill, O.P., A. Neher, B. Sakmann, and F.J. Sigworth. 1981. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflügers Arch. 391:85-100.
    • (1981) Pflügers Arch. , vol.391 , pp. 85-100
    • Hamill, O.P.1    Neher, A.2    Sakmann, B.3    Sigworth, F.J.4
  • 18
    • 0030742875 scopus 로고    scopus 로고
    • Structure and function of the low conductance KATP channel, ROMK
    • Hebert, S.C., and W.H. Wang. 1997. Structure and function of the low conductance KATP channel, ROMK. Wien. Klin. Worhensckr. 109:471-476.
    • (1997) Wien. Klin. Worhensckr. , vol.109 , pp. 471-476
    • Hebert, S.C.1    Wang, W.H.2
  • 20
    • 0024520745 scopus 로고
    • Site-directed mutagenesis by overlap extension using the polymerase chain reaction
    • Ho, S.N., H.D. Hunt, R.M. Horton, J.K. Pullen, and L.R. Pease. 1989. Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene. 77:51-59.
    • (1989) Gene. , vol.77 , pp. 51-59
    • Ho, S.N.1    Hunt, H.D.2    Horton, R.M.3    Pullen, J.K.4    Pease, L.R.5
  • 21
    • 8044222737 scopus 로고    scopus 로고
    • Mutations in the gene encoding the inwardly-rectifying renal potassium channel, ROMK, cause the antenatal variant of Bartter syndrome: Evidence for genetic heterogeneity
    • Karolyi, L., M. Konrad, A. Kockerling, A. Ziegler, D.K. Zimmerman, B. Roth, C. Wieg, K.-H. Grzeschik, M.C. Kock, H.W. Seyberth, et al. 1997. Mutations in the gene encoding the inwardly-rectifying renal potassium channel, ROMK, cause the antenatal variant of Bartter syndrome: evidence for genetic heterogeneity. Hum. Mol. Genet. 6:17-26.
    • (1997) Hum. Mol. Genet. , vol.6 , pp. 17-26
    • Karolyi, L.1    Konrad, M.2    Kockerling, A.3    Ziegler, A.4    Zimmerman, D.K.5    Roth, B.6    Wieg, C.7    Grzeschik, K.-H.8    Kock, M.C.9    Seyberth, H.W.10
  • 22
    • 0031682918 scopus 로고    scopus 로고
    • Localization of the ROMK potassium channel to the apical membrane of distal nephron in rat kidney
    • Kohda, Y., W. Ding, E. Phan, I. Housini, J. Wang, R.A. Star, and C.L. Huang. 1998. Localization of the ROMK potassium channel to the apical membrane of distal nephron in rat kidney. Kidney Int. 54:1214-1223.
    • (1998) Kidney Int. , vol.54 , pp. 1214-1223
    • Kohda, Y.1    Ding, W.2    Phan, E.3    Housini, I.4    Wang, J.5    Star, R.A.6    Huang, C.L.7
  • 24
    • 0021770860 scopus 로고
    • Functional messenger RNAs are produced by SP6 in vitro transcription of cloned cDNAs
    • Krieg, P.A., and D.A. Melton. 1984. Functional messenger RNAs are produced by SP6 in vitro transcription of cloned cDNAs. Nucleic Acids Res. 12:7057-7070.
    • (1984) Nucleic Acids Res. , vol.12 , pp. 7057-7070
    • Krieg, P.A.1    Melton, D.A.2
  • 25
    • 0028108544 scopus 로고
    • A conductance maximum observed in an inward-rectifier potassium channel
    • Lu, Z., and R. Mackinnon. 1994. A conductance maximum observed in an inward-rectifier potassium channel. J. Gen. Physiol. 104:477-486.
    • (1994) J. Gen. Physiol. , vol.104 , pp. 477-486
    • Lu, Z.1    Mackinnon, R.2
  • 27
    • 0025762715 scopus 로고
    • Determination of the subunit stoichiometry of a voltage-activated potassium channel
    • Mackinnon, R. 1991. Determination of the subunit stoichiometry of a voltage-activated potassium channel. Nature. 350:232-235.
    • (1991) Nature , vol.350 , pp. 232-235
    • Mackinnon, R.1
  • 29
    • 0029826866 scopus 로고    scopus 로고
    • + channel (ROMK2) to the inhibitory sulfonylurea compound glibenclamide is enhanced by coexpression with the ATP-binding cassette transporter cystic fibrosis transmembrane regulator
    • + channel (ROMK2) to the inhibitory sulfonylurea compound glibenclamide is enhanced by coexpression with the ATP-binding cassette transporter cystic fibrosis transmembrane regulator. Proc. Natl. Acad. Sci. USA. 93:8083-8088.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 8083-8088
    • McNicholas, C.M.1    Guggino, W.B.2    Schwiebert, E.M.3    Hebert, S.C.4    Giebisch, G.5    Egan, M.E.6
  • 32
    • 0022911410 scopus 로고
    • Patch clamp measurements on Xenopus laevis oocytes: Currents through endogenous channels and implanted acetylcholine receptor and sodium channels
    • Methfessel, C., V. Witzemann, T. Takahashi, M. Mishina, S. Numa, and B. Sakmann. 1986. Patch clamp measurements on Xenopus laevis oocytes: currents through endogenous channels and implanted acetylcholine receptor and sodium channels. Pflügers Arch. 407:577-588.
    • (1986) Pflügers Arch. , vol.407 , pp. 577-588
    • Methfessel, C.1    Witzemann, V.2    Takahashi, T.3    Mishina, M.4    Numa, S.5    Sakmann, B.6
  • 33
    • 0032567106 scopus 로고    scopus 로고
    • Crystal structure and functional analysis of the HERG potassium channel N terminus: A eukaryotic PAS domain
    • Morais Cabral, J.H., A. Lee, S.L. Gohen, B.T. Chait, M. Li, and R. Mackinnon. 1998. Crystal structure and functional analysis of the HERG potassium channel N terminus: a eukaryotic PAS domain. Cell. 95:649-655.
    • (1998) Cell , vol.95 , pp. 649-655
    • Morais Cabral, J.H.1    Lee, A.2    Gohen, S.L.3    Chait, B.T.4    Li, M.5    Mackinnon, R.6
  • 34
    • 0030934798 scopus 로고    scopus 로고
    • Inward rectifier potassium channels
    • Nichols, C.G., and A.N. Lopatin. 1997. Inward rectifier potassium channels. Annu. Rev. Physiol. 59:171-191.
    • (1997) Annu. Rev. Physiol. , vol.59 , pp. 171-191
    • Nichols, C.G.1    Lopatin, A.N.2
  • 35
    • 0030874744 scopus 로고    scopus 로고
    • Is the secretory K channel in the rat CCT ROMK?
    • Palmer, L.G., H. Choe, and G. Frindt. 1997. Is the secretory K channel in the rat CCT ROMK? Am. J. Physiol. 273:F404-F410.
    • (1997) Am. J. Physiol. , vol.273
    • Palmer, L.G.1    Choe, H.2    Frindt, G.3
  • 38
    • 0033545687 scopus 로고    scopus 로고
    • Structure of a molecular brake
    • Sansom, M.S.P. 1999. Structure of a molecular brake. Curr. Biol. 9:R173-R175.
    • (1999) Curr. Biol. , vol.9
    • Sansom, M.S.P.1
  • 39
    • 0032545369 scopus 로고    scopus 로고
    • pH-dependent gating of ROMK (Kir 1.1) channels involves conformational changes in both N and C termini
    • Schulte, U., H. Hahn, H. Wiesinger, J.P. Ruppersberg, and B. Fakler. 1998. pH-dependent gating of ROMK (Kir 1.1) channels involves conformational changes in both N and C termini. J. Biol. Chem. 273:34575-34579.
    • (1998) J. Biol. Chem. , vol.273 , pp. 34575-34579
    • Schulte, U.1    Hahn, H.2    Wiesinger, H.3    Ruppersberg, J.P.4    Fakler, B.5
  • 40
    • 0031803541 scopus 로고    scopus 로고
    • Functional consequences of ROMK mutants linked to antenatal Bartter's syndrome and implications for treatment
    • Schwalbe, R.A., L. Bianchi, E.A. Accili, and A.M. Brown. 1998. Functional consequences of ROMK mutants linked to antenatal Bartter's syndrome and implications for treatment. Hum. Mol. Genet. 7:975-980.
    • (1998) Hum. Mol. Genet. , vol.7 , pp. 975-980
    • Schwalbe, R.A.1    Bianchi, L.2    Accili, E.A.3    Brown, A.M.4
  • 41
    • 0023478292 scopus 로고
    • Data transformations for improved display and fitting of single-channel dwell time histograms
    • Sigworth, F.J., and S.M. Sine. 1987. Data transformations for improved display and fitting of single-channel dwell time histograms. Biophys. J. 52:1047-1054.
    • (1987) Biophys. J. , vol.52 , pp. 1047-1054
    • Sigworth, F.J.1    Sine, S.M.2
  • 42
    • 0030032699 scopus 로고    scopus 로고
    • Banter's syndrome, hypokalaemic alkalosis with hypercalciuria, is caused by mutations in the Na-K-2Cl cotransporter NKCC2
    • Simon, D.B., F.E. Karet, J.M. Hamdan, A. DiPietro, S.A. Sanjad, and R.P. Lifton. 1996a. Banter's syndrome, hypokalaemic alkalosis with hypercalciuria, is caused by mutations in the Na-K-2Cl cotransporter NKCC2. Nat. Genet. 13:183-188.
    • (1996) Nat. Genet. , vol.13 , pp. 183-188
    • Simon, D.B.1    Karet, F.E.2    Hamdan, J.M.3    DiPietro, A.4    Sanjad, S.A.5    Lifton, R.P.6
  • 44
    • 9044235777 scopus 로고    scopus 로고
    • Gitelman's variant of Bartter's syndrome, inherited hypokalaemic alkalosis, is caused by mutations in the thiazide-sensitive Na-Cl cotransporter
    • Simon, D.B., C. Nelson-Williams, M.J. Bia, D. Ellison, F.E. Karet, A.M. Molina, I. Vaara, F. Iwata, H.M. Cushner, M. Koolen, et al. 1996c. Gitelman's variant of Bartter's syndrome, inherited hypokalaemic alkalosis, is caused by mutations in the thiazide-sensitive Na-Cl cotransporter. Nat. Genet. 12:24-30.
    • (1996) Nat. Genet. , vol.12 , pp. 24-30
    • Simon, D.B.1    Nelson-Williams, C.2    Bia, M.J.3    Ellison, D.4    Karet, F.E.5    Molina, A.M.6    Vaara, I.7    Iwata, F.8    Cushner, H.M.9    Koolen, M.10
  • 46
    • 0030606298 scopus 로고    scopus 로고
    • Regions responsible for the assembly of inwardly rectifying potassium channels
    • Tinker, A., Y.N. Jan, and L.Y. Jan. 1996. Regions responsible for the assembly of inwardly rectifying potassium channels. Cell. 87:857-868.
    • (1996) Cell , vol.87 , pp. 857-868
    • Tinker, A.1    Jan, Y.N.2    Jan, L.Y.3
  • 47
    • 0030863675 scopus 로고    scopus 로고
    • Interdomain interaction underlying activation of cyclic nucleotide-gated channels
    • Varnum, M.D., and W.N. Zagotta. 1997. Interdomain interaction underlying activation of cyclic nucleotide-gated channels. Science. 278:110-113.
    • (1997) Science , vol.278 , pp. 110-113
    • Varnum, M.D.1    Zagotta, W.N.2
  • 49
    • 0025269167 scopus 로고
    • A potassium channel in the apical membrane of rabbit thick ascending limb of Henle's loop
    • Wang, W.H., S. White, J. Geibel, and G. Giebisch. 1990b. A potassium channel in the apical membrane of rabbit thick ascending limb of Henle's loop. Am. J. Physiol. 258:F244-F253.
    • (1990) Am. J. Physiol. , vol.258
    • Wang, W.H.1    White, S.2    Geibel, J.3    Giebisch, G.4
  • 52
    • 0029869002 scopus 로고    scopus 로고
    • + channel, ROMK, by cyclic AMP-dependent protein kinase
    • + channel, ROMK, by cyclic AMP-dependent protein kinase. J. Biol. Chem. 271:9313-9319.
    • (1996) J. Biol. Chem. , vol.271 , pp. 9313-9319
    • Xu, Z.1    Yang, Y.2    Hebert, S.C.3
  • 54
    • 13344262697 scopus 로고
    • Determination of the subunit stoichiometry of an inwardly rectifying potassium channel
    • Yang, J., Y.N. Jan, and L.Y. Jan. 1995b. Determination of the subunit stoichiometry of an inwardly rectifying potassium channel. Neuron. 15:1441-1447.
    • (1995) Neuron , vol.15 , pp. 1441-1447
    • Yang, J.1    Jan, Y.N.2    Jan, L.Y.3
  • 55
    • 0025676531 scopus 로고
    • Characterization of stretch-activated ion channels in Xenopus oocytes
    • Yang, X.C., and F. Sachs. 1990. Characterization of stretch-activated ion channels in Xenopus oocytes. J. Physiol. 431:103-122.
    • (1990) J. Physiol. , vol.431 , pp. 103-122
    • Yang, X.C.1    Sachs, F.2


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