Efficacy of vitamin E, phosphatidyl choline, and pyruvate on buffering neuronal degeneration and oxidative stress in cultured cortical neurons and in central nervous tissue of apolipoprotein E-deficient mice

Free Radical Biology and Medicine

Volumn 33, Issue 2, 2002, Pages 276-282

  Shea, Thomas B ^a,b   Ekinci, Fatma J ^a,b   Ortiz, Daniela ^a   Dawn Linsley, Maria ^a   Wilson, Thomas O ^c   Nicolosi, Robert J ^a  

^a UNIVERSITY OF MASSACHUSETTS LOWELL   (United States)

^b University of Massachusetts Lowell   (United States)

^c AST Products Inc   (United States)

Author keywords

Antioxidants; Apolipoprotein E; Free radicals; Neurodegeneration; Oxidative stress; Transgenic mice; Vitamin E

Indexed keywords

ALPHA TOCOPHEROL; APOLIPOPROTEIN E; HYDROGEN PEROXIDE; PHOSPHATIDYLCHOLINE; PYRUVIC ACID; ANTIOXIDANT; NEUROPROTECTIVE AGENT; PEROXIDE; PYRUVIC ACID DERIVATIVE; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; BRAIN CELL; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DIETARY INTAKE; DRUG EFFICACY; EMBRYO; GENE DELETION; MOUSE; NERVE CELL CULTURE; NERVE CELL DEGENERATION; NEURITE; NEUROPROTECTION; NONHUMAN; NUTRITIONAL DEFICIENCY; OXIDATIVE STRESS; PRIORITY JOURNAL; WOUND HEALING; ANIMAL; BRAIN CORTEX; DRUG COMBINATION; DRUG EFFECT; MOUSE MUTANT; NERVE CELL; NERVE DEGENERATION;

ANIMAL; ANTIOXIDANTS; APOLIPOPROTEINS E; CEREBRAL CORTEX; DRUG COMBINATIONS; HYDROGEN PEROXIDE; MICE; MICE, KNOCKOUT; NERVE DEGENERATION; NEURONS; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PEROXIDES; PHOSPHATIDYLCHOLINES; PYRUVATES; REACTIVE OXYGEN SPECIES; VITAMIN E; ANIMALS;

MURINAE; MUS MUSCULUS;

EID: 0037098873     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(02)00872-9     Document Type: Article

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