Simulations of biomolecules: Characterization of the early steps in the pH-induced conformational conversion of the hamster, bovine and human forms of the prion protein

Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences

Volumn 360, Issue 1795, 2002, Pages 1165-1178

  Alonso, Darwin O V ^a   An, Chahm ^a   Daggett, Valerie ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Bovine spongiform encephalopathy; Molecular dynamics; Prion protein; Protein misfolding

Indexed keywords

NERVE PROTEIN; PRION PROTEIN;

ANIMAL; ARTICLE; CATTLE; CHEMICAL STRUCTURE; CHEMISTRY; CLASSIFICATION; COMPARATIVE STUDY; COMPUTER SIMULATION; HAMSTER; HUMAN; PH; PRION; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN TERTIARY STRUCTURE; SPECIES DIFFERENCE;

ANIMALS; CATTLE; COMPUTER SIMULATION; CRICETINAE; HUMANS; HYDROGEN-ION CONCENTRATION; MODELS, MOLECULAR; NERVE TISSUE PROTEINS; PRIONS; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; PRPC PROTEINS; PRPSC PROTEINS; SPECIES SPECIFICITY;

EID: 0037098209     PISSN: 1364503X     EISSN: None     Source Type: Journal    
DOI: 10.1098/rsta.2002.0986     Document Type: Conference Paper

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