Verapamil decreases glucuronidase activity in the gut

Biochemical Pharmacology

Volumn 63, Issue 8, 2002, Pages 1575-1578

  Lötsch, Jörn ^a   Sperker, Bernhard ^b   Kroemer, Heyo K ^b   Geisslinger, Gerd ^a  

^a UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^b UNIVERSITY OF GREIFSWALD   (Germany)

Author keywords

Glucuronidase; Interaction; Intestinal pharmacokinetics; Metabolism; Morphine 6 glucuronide; Rats

Indexed keywords

BETA GLUCURONIDASE; GLUCURONIDE; MORPHINE; MORPHINE 3 GLUCURONIDE; MORPHINE 6 GLUCURONIDE; VERAPAMIL;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BIOAVAILABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ESCHERICHIA COLI; GLUCURONIDATION; IC 50; INTESTINE ABSORPTION; MALE; METABOLISM; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BIOLOGICAL AVAILABILITY; CALCIUM CHANNEL BLOCKERS; DRUG INTERACTIONS; GLUCURONIDASE; INTESTINAL MUCOSA; INTESTINES; MALE; MODELS, ANIMAL; MORPHINE DERIVATIVES; P-GLYCOPROTEIN; RATS; RATS, SPRAGUE-DAWLEY; VERAPAMIL;

EID: 0037091070     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(02)00881-X     Document Type: Article

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