Leptin affects the electrical activity of neurones in the hypothalamic supraoptic nucleus

Brain Research Bulletin

Volumn 57, Issue 5, 2002, Pages 721-725

  Honda, Kazumasa ^a   Narita, Kazumi ^a   Murata, Takuya ^a   Higuchi, Takashi ^a  

^a UNIVERSITY OF FUKUI   (Japan)

Author keywords

Brain slice; Electrophysiology; Leptin; Oxytocin neurone; Vasopressin neurone

Indexed keywords

LEPTIN; OXYTOCIN; POTASSIUM CHANNEL; TOLBUTAMIDE;

ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; DOSE RESPONSE; ELECTRIC ACTIVITY; IN VITRO STUDY; MALE; NONHUMAN; OBESITY; PRIORITY JOURNAL; RAT; SUPRAOPTIC NUCLEUS;

ACTION POTENTIALS; ANIMALS; CARRIER PROTEINS; HYPOGLYCEMIC AGENTS; LEPTIN; MALE; MUTATION; NEURAL INHIBITION; NEURONS; OXYTOCIN; POTASSIUM CHANNELS; RATS; RATS, WISTAR; RATS, ZUCKER; RECEPTORS, CELL SURFACE; SUPRAOPTIC NUCLEUS; SYNAPTIC TRANSMISSION; TOLBUTAMIDE; VASOPRESSINS;

EID: 0037086629     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0361-9230(01)00788-2     Document Type: Article

References (32)

1. Mechanisms of the glycaemic effects of sulfonylureas
2. Expression of leptin receptor isoforms in rat brain microvessels
3. Differential regulation of leptin receptor but not orexin in the hypothalamus of the lactating rat
4. Suppression of leptin during lactation; Contribution of the suckling stimulus versus milk production
5. Recombinant mouse OB protein; Evidence for a periphera signal linking adiposity and central neural networks
6. The weight-reducing effect of an intracerebroventricular bolus injection of leptin in genetically obese fa/fa rats. Reduced sensitivity compared with lean animals
7. Distributions of leptin receptor mRNA isoforms in the rat brain
8. Leptin receptor immunoreactivity in chemically defined target neurons of the hypothalamus
9. Expression of leptin receptor mRNA in the hypothalamic arcuate nucleus-relationship with NPY neurones
10. Weight-reducing effects of the plasma protein encoded by the obese gene
11. Leptin activates ATP-sensitive potassium channels in the rat insulin-secreting cell line, CRI-G1
12. Leptin affects electrical activity of hypothalamic supraoptic neurosecretory cells in vitro
13. Excitation of oxytocin cells in the hypothalamic supraoptic nucleus by electrical stimulation of the dorsal penile nerve and tactile stimulation of the penis in the rat
14. GABAergic projection from the arcuate nucleus to the supraoptic nucleus in the rat
15. Localization of leptin receptor mRNA and the long form splice variant (Ob-Rb) in mouse hypothalamus and adjacent brain regions by in situ hybridization
16. Localization of leptin receptor (Ob-R) messenger ribonucleic acid in the rodent hindbrain
17. Acute effects of exercise on circulating leptin in lean and genetically obese fa/fa rats
18. Effects of the obese gene product on body weight regulation in ob/ob mice
19. Leptin receptor missense mutation in the fatty Zucker rat
20. Lactation suppresses diurnal rhythm of serum leptin
21. Leptin depolarizes rat hypothalamic paraventricular nucleus neurons
22. Recombinant ob-gene product reduces food intake in fasted mice
23. Immunohistochemical localization of leptin receptor in the rat brain
24. Effects of leptin on insulin sensitivity in normal rats
25. Leptin inhibits hypothalamic neurons by activation of ATP-sensitive potassium channels
26. Identification and expression cloning of a leptin receptor, OB-R
27. Comparing the hypothalamic and extrahypothalamic actions of endogenous hyperleptinemia
28. Centrally administered murine leptin stimulates plasma arginine-vasopressin secretion and increases the level of mRNA expression in the supraoptic nucleus of conscious rats
29. Localization of leptin receptor immunoreactivity in the lean and obese Zucker rat brain
30. Regulation of water balance in genetically obese rats
31. Expression and localization of the leptin receptor in endocrine and neuroendocrine tissues of the rat
32. Positional cloning of the mouse obese gene and its human homologue