Mechanisms of the clycaemic effects of sulfonylureas

Hormone and Metabolic Research

Volumn 28, Issue 9, 1996, Pages 456-463

  Ashcroft, Frances M ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

ATP sensitive K channel; Insulin secretion; Kir 6.2; Pancreatic B cell; Sulfonylurea; Sulfonylurea receptor; SUR1

Indexed keywords

POTASSIUM CHANNEL; SULFONYLUREA DERIVATIVE; SULFONYLUREA RECEPTOR; UNCLASSIFIED DRUG; ABC TRANSPORTER; ADENOSINE TRIPHOSPHATE; ANTIDIABETIC AGENT; DRUG RECEPTOR; INWARDLY RECTIFYING POTASSIUM CHANNEL;

CONFERENCE PAPER; GLUCOSE METABOLISM; HUMAN; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; GENETICS; GLUCOSE BLOOD LEVEL; ISOLATION AND PURIFICATION; METABOLISM; MOLECULAR CLONING; REVIEW;

ADENOSINE TRIPHOSPHATE; ATP-BINDING CASSETTE TRANSPORTERS; BLOOD GLUCOSE; CLONING, MOLECULAR; HUMANS; HYPOGLYCEMIC AGENTS; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RECEPTORS, DRUG; SULFONYLUREA COMPOUNDS;

EID: 0029658824     PISSN: 00185043     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-979837     Document Type: Conference Paper

References (59)

1. Aguilar-Bryan, L., D. A. Nelson, Q. A. Vu, B. Hmphrey, A. E. Boyd III: Photoaffinity labeling and partial purification of the β-cell sulphonylurea receptor using a novel, biologically active glyburide. J. Biol. Chem. 265: 8218-8224 (1990)
2. ATP channels in HIT cells. J. Biol. Chem. 267: 14934-14940 (1992)
3. Aguilar-Bryan, L., C. G. Nichols, S. W. Wechsler, J. P. Clement, A. E. Boyd, G. González, H. Herrera-Sosa, K. Nguy, J. Bryan, D. A. Nelson: Cloning of the β-cell high-affinity sulphonylurea receptor: a regulator of insulin secretion. Science 268: 423-425 (1995)
4. Ämmälä, C., A. Moorhouse, F. Gribble, R. Ashfield, P. Proks, P. A. Smith, H. Sakura, B. Coles, S. J. H. Ashcroft, F. M. Ashcroft: Promiscuous coupling between the sulphonylurea receptor and inwardly-rectifying potassium channels. Nature 379: 545-548 (1996)
5. Ashcroft, F. M.: Adenosine 5′-triphosphate-sensitive potassium channels. Ann. Rev. Neurosci 11: 97-118 (1988)
6. 2+ ions. J. Physiol. 416: 349-367 (1989)
7. Ashcroft, F. M., P. Rorsman: Electrophysiology of the pancreatic β-cell. Prog. Biophys. Molec. ÖBiol. 54: 87-143 (1990)
8. Ashcroft, F. M., S. J. H. Ashcroft: Properties and functions of ATP-sensitive K-channels. Cell. Sig. 2: 197-214 (1990)
9. Ashcroft, F. M., S. J. H. Ashcroft: The sulphonylurea receptor. Biochem. Biophys. Acta 1175: 45-59 (1992)
10. ATP channel. Nature 370: 456-459 (1994)
11. + channel. Proc. Natl. Acad. Sci. USA 85: 9816-9820 (1988)
12. + channels. Biochemistry 31: 6328-6332 (1992)
13. D in hippocampal neurones. Can. J. Physiol. Pharmacol. 70: 306-307 (1992)
14. Dean, P. M., E. K. Mathews: Electrical activity in pancreatic islet cells. Nature 219: 389-390 (1968)
15. Doupnik, C. A., N. Davidson, H. A. Lester: The inward rectifier potassium channel family. Curr. Op. Cell Biol. 5: 268-278 (1995)
16. + channels. J. Physiol. 489.P: 7S (1995)
17. - channels by protein kinase A corrected by insertion of CFTR. Nature 358: 581-584 (1992)
18. Eliasson, L., E. Renstrøom, C. Ämmälä, A. chibalin, J. T. Deeney, P. R. Flatt, J. Gabel, J. Gromada, O. Larsson, P. Linstrom, C. Rhodes, P. Rorsman: PKC-dependent stimulation of exocytosis by sulfonylureas in pancreatic β-cells. Science 271: 813-815 (1996)
19. Faehling, M.: Studies of ATP-sensitive whole-cell currents in pancreatic β-cells. M. Sc. thesis. University of Oxford (1995)
20. Hardy, S. P., H. R. Goodfellow, M. A. Valverde, D. R. Gill, F. A. Sépulveda, C. F. Higgins: Protein kinase C-mediated phosphorylation of the human multidrug resistance protein regulates cell-volume activated chloride channels. EMBO J. 14: 68-75 (1995)
21. Henquin, J. C.: Tolbutamide stimulation and inhibition of insulin release: studies of the underlying mechanisms in rat islets. Diabetologia 18: 151-160 (1980)
22. Higgins, C.: ABC transporters: from microorganisms to man. Ann. Rev. Cell. Biol. 8: 67-113 (1992)
23. Higgins, C.: The ABC of channel regulation. Cell 82: 693-696 (1995)
24. Ho, K., C. G. Nichols, W. J. Lederer, J. Lytton, P. M. Vassilev, M. V. Kanazirska, S. C. Hebert: Cloning and expression of an inwardly rectifying ATP-regulated potassium channel. Nature 362: 31-38 (1993)
25. ATP: an inward rectifier subunit plus the sulphonylurea receptor. Science 270: 1166-1169 (1995a)
26. Inagaki, N., Y. Tsuura, N. Namba, K. Masuda, T. Gonoi, M. Horie, Y. Seino, M. Mizuta, S. Seino: Cloning and functional characterization of a novel ATP-sensitive potassium channel ubiquitously expressed in rat tissues, including pancreatic islets, pituitary, skeletal muscle, and heart. J. Biol. Chem. 270: 5691-5694 (1995b)
27. + channel and linkage studies in Japanese patients. Diabetes 46: 267-269 (1996)
28. Jaggar, J. H., E. A. Harding, C. Kane, R. F. L. James, N. J. M. London, M. J. Dunne: A comparison of the properties of potassium channels in cryopreserved and non-cryopreserved human insulin-secreting cells. EASD Islet Study Group Symposium. Book of Abstracts, B-17 (1994)
29. ATP channel and sulphonylurea receptor in the rat clonal insulin-secreting cell line CRI-DII. Proc. Roy. Soc. Lond. B253: 225-231 (1993)
30. 3H] glibenclamide. FEBS Lett. 229: 355-359 (1988)
31. +-channels. Diabetes Res. Clin. Prac. 28: S67-S80 (1995)
32. + channel proteins. Nture 374: 135-141 (1995)
33. Lee, K., S. E. Ozanne, I. C. M. Rowe, C. N. Hales, M. L. J. Ashford: The effects on trypsin of ATP-regulated potassium channel properties and sulphonylurea receptors in the CRI-G1 insulin secreting cell line. Mol. Pharmacol. 45: 176-185 (1994)
34. 86Rb efflux and glibenclamide binding. Pflügers Arch. 415: 47-55 (1989)
35. Niki, I., M. Welsh, P.-O. Berggren, P. Hubbard, S. J. H. Ashcroft: Characterisation of the solubilised glibenclamide receptor in a hamster pancreatic β-cell line, HIT T15. Biochem. J. 277: 619-624 (1991)
36. 2+-regulated secretion by protein kinase C. J. Biol. Chem. 267: 23972 (192)
37. Ozanne, S. E.: A study of the sulphonylurea receptors in pancreatic β-cells. D. Phil. thesis. University of Cambridge (1994)
38. Ozanne, S. E., P. C. Guest, J. C. Huton, C. N. Hales: Intracellular localization and molecular heterogeneity of the sulphonylurea receptor in insulin-secreting cells. Diabetologia 38: 277-282 (1995)
39. Panten, U., J. Burgfeld, F. Goerke, M. Rennicke, M. Schwanstecher, A. Wallasch, B. J. Zünckler, S. Lenzen: Control of insulin secretion by sulphonylureas, meglitinide and diazoxide in relation to their binding to the sulphonylurea receptor in pancreatic islets. Biochem. Pharmacol. 38: 1217-1229 (1989)
40. Proks, P., F. M. Ashcroft: Modification of K-ATP channels in pancreatic β-cells by trypsin. Pflügers Arch. 424: 63-72 (1993)
41. + channel in the human neuroblastoma cell line SH-ST5Y. Neurosci Lett. 135: 27-40 (1992)
42. + currents in pancreatic β-cells are regulated by intracellular ATP. Pflügers Arch. 405: 305-309 (1985)
43. Ruknudin, A., D. H. Schulze, S. K. Sullivan, W. J. Lederer, P. A. Welling: Functional modulation of ROMK1 channels by an ATP-binding cassette protein CFTR in Xenopus oocytes. Biophys. J. 70: A309 (1996)
44. Sakura, H., C. Ämmälä, P. A. Smith, F. M. Gribble, F. M. Ashcroft: Cloning and functional expression of the cDNA encoding a novel ATP-sensitive potassium channel expressed in pancreatic β-cells, brain, heart and skeletal muscle. FEBS Lett. 377: 338-344 (1995)
45. Schwanstecher, M., S. Löser, F. Chudziak, U. Panten: Identification of a 38 kD high affinity sulphonylurea receptor in insulin-secreting cells and cerebral cortex. J. Biol. Chem. 269: 17768-17771 (1994)
46. Schwanstecher, M., C. Schwanstecher, C. Dickel, F. Chudziak, A. Moshira, U. Panten: Location of the sulphonylurea receptor at the cytoplasmic face of the beta-cell membrane. Br. J. Pharmacol. 113: 903-911 (1995)
47. Shaw, S. Y., W. Fenderson, P. Reiss, M. Bernatowicz, G. R. Matsueda: Purification and identification of two low affinity glyburide binding proteins from HIT cell membrane. International conference on ATP-sensitive K-channels and sulphonylurea receptors. Abstracts p. 159
48. + channel regulataors on cystic fibrosis transmembrane conductance regulator chloride currents. J. Gen. Physiol. 100: 573-591 (1992)
49. 2+ and polyamines. J. Physiol. University College London meeting, in press (1996)
50. Skeer, J. M., P. Dégano, B. Coles, M. Potier, F. M. Ashcroft, S. J. H. Ashcroft: Determination of the molecular mass of the native β-cell sulphonylurea receptor. FEBS Lett. 338: 98-102 (1994)
51. Stirling, B., N. J. Cox, C. L. Hanis, R. S. Spielman, P. Concannon: Linkage studies in NIDDM with markers near the sulphonylurea receptor gene. Diabetologia 38: 1479-1481 (1995)
52. Sturgess, N. C., M. L. J. Ashford, D. L. Cook, C. N. Hales: The sulphonylurea receptor may be an ATP-sensitive potassium channel. Lancet 474-475 (1985)
53. Stutts, M. J., ÖC. M. Canessa, J. C. Olsen, M. Hamrick, J. A. Cohn, B. C. Rossier, R. C. Boucher: CFTR as a cAMP-dependent regulator of sodium channels. Science 269: 805-806 (1995)
54. + conductance in pancreatic zymogen granules: block by glyburide and activation by diazoxide. Am. J. Physiol. 129: 253-266 (1992)
55. Thomas, P. M., G. J. Cote, N. Wohllk, B. Haddad, P. M. Mathew, W. Rabl, L. Aguilar-Bryan, R. F. Gagel, J. Bryan: Mutations in the sulphonylurea receptor gene in familial persistent hyperinsulinaemic hypoglycaemia of infancy. Science 268: 425-429 (1995)
56. +-channel in pancreatic β-cells. Pflügers Arch. 407: 493-499 (1986)
57. Tsuchiya, K., W. Wang, G. Giebisch, P. A. Welling: ATP is a coupling modulator of parallel Na, K-ATP-ase-K-channel activity in renal proximal tubule. Proc. Natl. Acad. Sci. USA 89: 6418-6422 (1992)
58. 2+-regulated secretion in permeabilised neuroendocrine cells. Cell 79: 765 (1992)
59. + channel. Neuron 14: 1047-1054 (1995)