Characterization of the surfactin synthetase C-terminal thioesterase domain as a cyclic depsipeptide synthase

Biochemistry

Volumn 41, Issue 45, 2002, Pages 13350-13359

  Tseng, Claire C ^a   Bruner, Steven D ^a   Kohli, Rahul M ^a   Marahiel, Mohamed A ^b   Walsh, Christopher T ^a   Sieber, Stephan A ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

SURFACTIN PEPTIDES;

CHARACTERIZATION; CRYSTAL STRUCTURE; ENZYME INHIBITION; HYDROLYSIS; SURFACE ACTIVE AGENTS;

BIOCHEMISTRY;

ALANINE; ARGININE; ASPARTIC ACID; BETA HYDROXY BUTYRYL HEPTAPEPTIDYL THIOESTER; BORONIC ACID DERIVATIVE; CATION; CYCLODEPSIPEPTIDE; CYSTEINE; FATTY ACID; HEPTAPEPTIDE; HISTIDINE; LYSINE; MUTANT PROTEIN; PEPTIDE SYNTHASE; SERINE; SURFACTIN; THIOESTER; THIOL ESTER HYDROLASE; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYCLIZATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; HYDROLYSIS; KINETICS; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN;

AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; BACILLUS SUBTILIS; BACTERIAL PROTEINS; BETA-ALANINE; BORONIC ACIDS; CRYSTALLOGRAPHY, X-RAY; CYSTEAMINE; ENZYME INHIBITORS; HYDROLYSIS; MACROLIDES; MUTAGENESIS, SITE-DIRECTED; PEPTIDE FRAGMENTS; PEPTIDE SYNTHASES; PEPTIDES, CYCLIC; PROTEIN STRUCTURE, TERTIARY; SUBSTRATE SPECIFICITY; THIOLESTER HYDROLASES;

ILEX COOKII;

EID: 0037069317     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi026592a     Document Type: Article

References (25)

1. Kohli, R. M., Trauger, J. W., Schwarzer, D., Marahiel, M. A., and Walsh, C. T. (2001) Biochemistry 40, 7099-7108.
2. Schwarzer, D., and Marahiel, M. A. (2001) Naturwissenschaften 88, 93-101.
3. Trauger, J. W., Kohli, R. M., and Walsh, C. T. (2001) Biochemistry 40, 7092-7098.
4. Skelton, N. J., Harding, M. M., Mortishire-Smith, R. J., Rahman, S. K., Williams, D. H., Rance, M. J., and Ruddock, J. C. (1991) J. Am. Chem. Soc. 113, 7522-7530.
5. Peypoux, F., Bonmatin, J. M., and Wallach, J. (1999) Appl. Microbiol. Biotechnol. 51, 553-563.
6. Cosmina, P., Rodriguez, F., de Ferra, F., Grandi, G., Perego, M., Venema, G., and van Sinderen, D. (1993) Mol. Microbiol. 8, 821-831.
7. Stein, T., Vater, J., Kruft, V., Otto, A., Wittmann-Liebold, B., Franke, P., Panico, M., McDowell, R., and Morris, H. R. (1996) J. Biol. Chem. 271, 15428-15435.
8. Bruner, S. D., Weber, T., Kohli, R. M., Schwarzer, D., Marahiel, M. A., Walsh, C. T., and Stubbs, M. T. (2002) Structure 10, 301-310.
9. Trauger, J. W., Kohli, R. M., Mootz, H. D., Marahiel, M. A., and Walsh, C. T. (2000) Nature 407, 215-218.
10. Martichonok, V., and Jones, J. B. (1996) J. Am. Chem. Soc. 118, 950-958.
11. Coutts, S. J., Adams, J., Krolikowski, D., and Snow, R. J. (1994) Tetrahedron Lett. 35, 5109-5112.
12. Wong, H., and Schotz, M. C. (2002) J. Lipid Res. 43, 993-999.
13. Osman, M., Ishigami, Y., Ishikawa, K., Ishizuka, Y., and Holmsen, H. (1994) Biotechnol. Lett. 16, 913-918.
14. Stoll, V. S., Eger, B. T., Hynes, R. C., Martichonok, V., Jones, J. B., and Pai, E. F. (1998) Biochemistry 37, 451-462.
15. Takahashi, L. H., Radhakrishnan, R., Rosenfield, R. E., Jr., and Meyer, E. F., Jr. (1989) Biochemistry 28, 7610-7617.
16. Kogen, H., Kiho, T., Nakayama, M., Furukawa, Y., Kinoshita, T., and Inukai, M. (2000) J. Am. Chem. Soc. 122, 10214-10215.
17. Hashizume, H., Igarashi, M., Hattori, S., Hori, M., Hamada, M., and Tageuchi, T. (2001) J. Antibiot. 54, 1054-1059.
18. Tsuge, K., Akiyama, T., and Shoda, M. (2001) J. Bacteriol. 183, 6265-6273.
19. Debono, M., Abbott, B. J., Molloy, R. M., Fukuda, D. S., Hunt, A. H., Daupert, V. M., Counter, F. T., Ott, J. L., Carrell, C. B., Howard, L. C., Boeck, L. D., and Hamill, R. L. (1988) J. Antibiot. 41, 1093-1105.
20. Kraut, J. (1977) Annu. Rev. Biochem. 46, 331-358.
21. Pazirandeh, M., Chirala, S. S., and Wakil, S. J. (1991) J. Biol. Chem. 266, 20946-20952.
22. Shaw-Reid, C. A., Kelleher, N. L., Losey, H. C., Gehring, A. M., and Walsh, C. T. (1999) Chem. Biol. 6, 385-400.
23. Kohli, R. M., Walsh, C. T., and Burkart, M. D. (2002) Nature 418, 658-661.
24. Bonmatin, J.-M., Genest, M., Labbé, H., and Ptak, M. (1994) Biopolymers 34, 975-896.
25. Kohli, R. M., Takagi, J., and Walsh, C. T. (2002) Proc. Natl. Acad. Sci. U.S.A. 99, 1247-1252.