RNA interference of signal peptide-binding protein SRP54 elicits deleterious effects and protein sorting defects in trypanosomes

Journal of Biological Chemistry

Volumn 277, Issue 49, 2002, Pages 47348-47357

  Liu, Li ^a   Liang, Xue hai ^a   Uliel, Shai ^a   Unger, Ron ^a   Ullu, Elisabetta ^a,b   Michaeli, Shulamit ^a  

^a BAR ILAN UNIVERSITY   (Israel)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEALTH; PROTEINS; PROTOZOA; RNA;

ENDOPLASMIC RETICULUM;

BIOCHEMISTRY;

CELL PROTEIN; DOUBLE STRANDED RNA; RNA; SIGNAL PEPTIDE; SIGNAL PEPTIDE BINDING PROTEIN; SIGNAL RECOGNITION PARTICLE; TRANSFER RNA; UNCLASSIFIED DRUG;

ARTICLE; CELL VACUOLE; CONTROLLED STUDY; CYTOKINESIS; ENDOPLASMIC RETICULUM; NONHUMAN; NUCLEOTIDE SEQUENCE; PARASITE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN LOCALIZATION; PROTEIN TARGETING; PROTEIN TRANSPORT; PROTOZOON; RNA EDITING; RNA PROCESSING; SIGNAL TRANSDUCTION; SPLICEOSOME; TRYPANOSOMA;

AMINO ACID SEQUENCE; ANIMALS; BLOTTING, NORTHERN; BLOTTING, WESTERN; CELL DIVISION; DATABASES; DNA, KINETOPLAST; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GENE SILENCING; MEMBRANE GLYCOPROTEINS; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; OLIGONUCLEOTIDES; PLASMIDS; PRECIPITIN TESTS; PROTEIN SORTING SIGNALS; PROTOZOAN PROTEINS; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL CYTOPLASMIC; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL RECOGNITION PARTICLE; TIME FACTORS; TRANSFECTION; TRYPANOSOMA BRUCEI BRUCEI;

EUKARYOTA; INVERTEBRATA; PROTOZOA; TRYPANOSOMA; TRYPANOSOMA BRUCEI; TRYPANOSOMA CRUZI;

EID: 0037033097     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M207736200     Document Type: Article

References (58)

1. Walter, P., and Johnson, E. (1994) Annu. Rev. Cell Biol. 10, 87-119
2. Lütcke, H. (1995) Eur. J. Biochem. 228, 531-550
3. Bui, N., and Strub, K. (1999) Biol. Chem. 380, 135-145
4. Dalbey, R. E., and Kuhn, A. (2000) Annu. Rev. Cell Dev. Biol. 16, 51-87
5. Walter, P., and Blobel, G. (1981) J. Cell Biol. 91, 557-561
6. Hegde, R. S., and Lingappa, V. R. (1999) Trends Cell Biol. 9, 132-137
7. Miller, J. D., Wilhelm, H., Gierasch, L., Gilmore, R., and Walter, P. (1993) Nature 366, 351-354
8. Romisch, K., Webb, J., Herz, J., Prehn, S., Frank, R., Vingron, M., and Dobberstein, B. (1989) Nature 340, 478-482
9. Keenan, R. J., Freymann, D. M., Walter, P., and Stroud, R. M. (1998) Cell 94, 181-191
10. Batey, R. T., Rambo, R. P., Lucast, L., Rha, B., and Doudna, J. A. (2000) Science 287, 1232-1239
11. Freymann, D. M., Keenan, R. J., Stroud, R. M., and Walter, P. (1997) Nature 385, 361-364
12. Montoya, G., Svensson, C., Luirink, J., and Sinning, I. (1997) Nature 385, 365-368
13. Phillips, G. J., and Silhavy, T. J. (1992) Nature 359, 744-746
14. Poritz, M. A., Bernstein, H. D., Strub, K., Zopf, D., Wilhelm, H., and Walter, P. (1990) Science 250, 1111-1117
15. Ulbrandt, N. D., Newitt, J. A., and Bernstein, H. D. (1997) Cell 88, 187-196
16. Seluanov, A., and Bibi, E. (1997) J. Biol. Chem. 272, 2053-2055
17. Lüirink, J., ten Hagen-Jongman, C. M., van der Weijden, C. C., Oudega, B., High, S., Dobberstein, B., and Kusters, R. (1994) EMBO J. 13, 2289-2296
18. Hann, B. C., and Walter, P. (1991) Cell 67, 131-144
19. Ogg, S. C., Poritz, M. A., and Walter, P. (1992) Mol. Biol. Cell 3, 895-911
20. Brown, J. D., Hann, B. C., Medzihradszky, K. F., Niwa, M., Burlingame, A. L., and Walter, P. (1994) EMBO J. 13, 4390-4400
21. Althoff, S. M., Stevens, S. W., and Wise, J. A. (1994) Mol. Cell. Biol. 14, 7839-7854
22. He, F., Yaver, D., Beckerich, J. M., Ogrydziak, D., and Gaillardin, C. (1990) Curr. Genet. 17, 289-292
23. Lee, I. H., and Ogrydziak, D. M. (1997) Yeast 13, 499-513
24. Sogin, M. L., Elwood, H. J., and Gunderson, J. H. (1986) Proc. Natl. Acad. Sci. U. S. A. 83, 1383-1387
25. Agabian, N. (1990) Cell 61, 1157-1160
26. Estevez, A. M., and Simpson, L. (1999) Gene (Amst.) 240, 247-260
27. Ben-Shlomo, H., Levitan, A., Béjà, O., and Michaeli, S. (1997) Nucleic Acids Res. 25, 4977-4984
28. Béjà, O., Ullu, E., and Michaeli, S. (1993) Mol. Biochem. Parasitol. 57, 223-229
29. Ben-Shlomo, H., Levitan, A., Shay, N. E., Goncharov, I., and Michaeli, S. (1999) J. Biol. Chem. 274, 25642-25650
30. Sharp, P. A. (2001) Genes Dev. 15, 485-490
31. Shi, H., Djikeng, A., Mark, T., Wirtz, E., Tschudi, C., and Ullu, E. (2000) RNA 6, 1069-1076
32. Wang, Z., Morris, J. C., Drew, M. E., and Englund, P. T. (2000) J. Biol. Chem. 275, 40174-40179
33. Ngo, H., Tschudi, C., Gull, K., and Ullu, E. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 14687-14692
34. Bastin, P., Ellis, K., Kohl, L., and Gull, K. (2000) J. Cell Sci. 113, 3321-3328
35. Estevez, A. M., Kempf, T., and Clayton, C. (2001) EMBO J. 20, 3831-3839
36. Wang, Z., and Englund, P. T. (2001) EMBO J. 20, 4674-4683
37. Moreira-Leite, F. F., Sherwin, T., Kohl, L., and Gull, K. (2001) Science 294, 610-612
38. Aphasizhev, R., Sbicego, S., Peris, M., Jang, S.-H., Aphasizheva, I., Simpson, A. M., Rivilin, A., and Simpson, L. (2002) Cell 108, 637-648
39. Wirtz, E., Leal, S., Ochatt, C., and Cross, G. A. (1999) Mol. Biochem. Parasitol. 99, 89-101
40. Carruthers, V. B., and Cross, G. A. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 8818-8821
41. Michaeli, S., Roberts, T. G., Watkins, K. P., and Agabian, N. (1990) J. Biol. Chem. 265, 10582-10588
42. Altschul, S. F., Gish, W., Miller, W., Myers, E. W., and Lipman, D. J. (1990) J. Mol. Biol. 215, 403-410
43. Bangs, J. D., Uyetake, L., Brickman, M. J., Balber, A. E., and Boothroyd, J. C. (1993) J. Cell Sci. 105, 1101-1113
44. Kelley, R. J., Alexander, D. L., Cowan, C., Balber, A. E., and Bangs, J. D. (1999) Mol. Biochem. Parasitol. 98, 17-28
45. Lee, M. G., Bihain, B. E., Russell, D. G., Deckelbaum, R. J., and Van der Ploeg, L. H. (1990) Mol. Cell. Biol. 10, 4506-4517
46. Lütcke, H., High, S., Römisch, K., Ashford, A. J., and Dobberstein, B. (1992) EMBO J. 11, 1543-1551
47. Al-Qahtani, A., Teilhet, M., and Mensa-Wilmot, K. (1998) Biochem. J. 331, 521-529
48. Michaeli, S., Goldring, A., and Agabian, N. (1993) Exp. Parasitol. 76, 308-313
49. Roditi, I., and Clayton, C. (1999) Mol. Biochem. Parasitol. 103, 99-100
50. Butikofer, P., Malherbe, T., Boschung, M., and Roditi, I. (2001) FASEB J. 15, 545-548
51. Butikofer, P., Vassella, E., Mehlert, A., Ferguson, M. A., and Roditi, I. (2002) Mol. Biochem. Parasitol. 119, 87-95
52. Field, H., Ali, B. R., Sherwin, T., Gull, K., Croft, S. L., and Field, M. C. (1999) J. Cell Sci. 112, 147-156
53. Michaeli, S., Podell, D., Agabian, N., and Ullu, E. (1992) Mol. Biochem. Parasitol. 51, 55-64
54. Ng, D. T., Brown, J. D., and Walter, P. (1996) J. Cell Biol. 134, 269-278
55. Herskovits, A. A., Seluanov, A., Rajsbaum, R., ten Hagen-Jongman, C. M., Henrichs, T., Bochkareva, E. S., Phillips, G. J., Probst, F. J., Nakae, T., Ehrmann, M., Luirink, J., and Bibi, E. (2001) EMBO Rep. 2, 1040-1046
56. Grosshans, H., Deinert, K., Hurt, E., and Simos, G. (2001) J. Cell Biol. 153, 745-762
57. Jacobson, M. R., and Pederson, T. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 7981-7986
58. He, X. P., Bataille, N., and Fried, H. M. (1994) J. Cell Sci. 107, 903-912