Evidence for coupling of membrane targeting and function of the signal recognition particle (SRP) receptor Fts Y

EMBO Reports

Volumn 2, Issue 11, 2001, Pages 1040-1046

  Herskovits, Anat A ^a   Seluanov, Andrei ^a   Rajsbaum, Ricardo ^a   Ten Hagen Jongman, Corinne M ^b   Henrichs, Tanja ^c   Bochkareva, Elena S ^a   Phillips, Gregory J ^d   Probst, Francis J ^e   Nakae, Taiji ^f   Ehrmann, Michael ^e   Luirink, Joen ^b   Bibi, Eitan ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b VU UNIVERSITY AMSTERDAM   (Netherlands)

^c CARDIFF UNIVERSITY   (United Kingdom)

^d IOWA STATE UNIVERSITY   (United States)

^e The College of William and Mary   (United States)

^f TOKAI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

MEMBRANE PROTEIN; SIGNAL RECOGNITION PARTICLE;

ARTICLE; CATALYSIS; CELL MEMBRANE; CELL SYNCHRONIZATION; CONTROLLED STUDY; ESCHERICHIA COLI; GENE INSERTION; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN TARGETING;

ESCHERICHIA COLI;

EID: 85041124470     PISSN: 1469221X     EISSN: None     Source Type: Journal    
DOI: 10.1093/embo-reports/kve226     Document Type: Article

References (21)

1. Neisseria gonorrhoeae PilA is an FtsY homolog
2. Model for signal sequence recognition from amino-acid sequence of 54K subunit of signal recognition particle
3. Putative integral membrane SRP receptors
4. Biotination of proteins in vivo. A post-translational modification to label, purify, and study proteins
5. Membrane association of FtsY, the E. coli SRP receptor
6. Anionic phospholipids are involved in membrane association of FtsY and stimulate its GTPase activity
7. TnTIN and TnTAP: Mini-transposons for site-specific proteolysis in vivo
8. Association of Escherichia coli ribosomes with the inner membrane requires the signal recognition particle receptor but is independent of the signal recognition particle
9. New prospects in studying the bacterial signal recognition particle pathway
10. An alternative protein targeting pathway in Escherichia coli: Studies on the role of FtsY
11. The functional integration of a polytopic membrane protein of Escherichia coli is dependent on the bacterial signal-recognition particle
12. A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples
13. A site-specific, membrane-dependent cleavage event defines the membrane binding domain of FtsY
14. Crystal structure of the NG domain from the signal-recognition particle receptor FtsY
15. Co-translational protein targeting catalyzed by the Escherichia coli signal recognition particle and its receptor
16. Homology of 54K protein of signal-recognition particle, docking protein and two E. coli proteins with putative GTP-binding domains
17. FtsY, the prokaryotic signal recognition particle receptor homologue, is essential for biogenesis of membrane proteins
18. Nascent membrane and presecretory proteins synthesized in Escherichia coli associate with signal recognition particle and trigger factor
19. The Escherichia coli SRP and SecB targeting pathways converge at the translocon
20. The signal recognition particle receptor α subunit assembles co-translationally on the endoplasmic reticulum membrane during an mRNA-encoded translation pause in vitro
21. The NG domain of the prokaryotic signal recognition particle receptor, FtsY is fully functional when fused to an unrelated integral membrane polypeptide