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Volumn 17, Issue 4, 2002, Pages 237-250

Effects of hyperammonemia and liver failure on glutamatergic neurotransmission

Author keywords

Glutamate receptors; Guanylate cyclase; Hepatic encephalopathy; Hyperammonemia; Nitric oxide; NMDA receptors

Indexed keywords

CYCLIC GMP; GLUTAMATE RECEPTOR; GLUTAMIC ACID; NEUROTRANSMITTER; NITRIC OXIDE;

EID: 0036981248     PISSN: 08857490     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1021993431443     Document Type: Conference Paper
Times cited : (76)

References (64)
  • 1
    • 0342470611 scopus 로고    scopus 로고
    • Chronic moderate hyperammonemia impairs active and passive avoidance behavior and conditional discrimination learning in rats
    • Aguilar, M.A., Miñarro, J., and Felipo, V. (2000). Chronic moderate hyperammonemia impairs active and passive avoidance behavior and conditional discrimination learning in rats. Exp. Neurol. 161:704-713.
    • (2000) Exp. Neurol. , vol.161 , pp. 704-713
    • Aguilar, M.A.1    Miñarro, J.2    Felipo, V.3
  • 3
    • 0029877408 scopus 로고    scopus 로고
    • Effects of ammonia on L-glutamate uptake in cultured astrocytes
    • Bender, A.S., and Norenberg, M.D. (1996). Effects of ammonia on L-glutamate uptake in cultured astrocytes. Neurochem. Res. 21:567-573.
    • (1996) Neurochem. Res. , vol.21 , pp. 567-573
    • Bender, A.S.1    Norenberg, M.D.2
  • 4
    • 0026635731 scopus 로고
    • Amino acid release from cerebral cortex in experimental acute liver failure, studied by in vivo cerebral cortex microdialysis
    • Bosman, D.K., Deutz, N.E.P., Maas, M.A.W., van Eijk, H.M.H., Smit, J.J.H., de Haan, J.G., et al. (1992). Amino acid release from cerebral cortex in experimental acute liver failure, studied by in vivo cerebral cortex microdialysis. J. Neurochem. 59:591-599.
    • (1992) J. Neurochem. , vol.59 , pp. 591-599
    • Bosman, D.K.1    Deutz, N.E.P.2    Maas, M.A.W.3    Van Eijk, H.M.H.4    Smit, J.J.H.5    De Haan, J.G.6
  • 5
    • 0026644382 scopus 로고
    • Evidence that hepatic encephalopathy results from a defect of glutamatergic synaptic regulation
    • Butterworth, R.F. (1992). Evidence that hepatic encephalopathy results from a defect of glutamatergic synaptic regulation. Mol. Neuropharmacol. 2:229-232.
    • (1992) Mol. Neuropharmacol. , vol.2 , pp. 229-232
    • Butterworth, R.F.1
  • 6
    • 0025845018 scopus 로고
    • Effect of portacaval anastomosis on electrically stimulated release of glutamate from hippocampal slices
    • Butterworth, R.F., Le, O., Lavoie, J., and Szerb, J.C. (1991). Effect of portacaval anastomosis on electrically stimulated release of glutamate from hippocampal slices. J. Neurochem. 56:1481-1484.
    • (1991) J. Neurochem. , vol.56 , pp. 1481-1484
    • Butterworth, R.F.1    Le, O.2    Lavoie, J.3    Szerb, J.C.4
  • 7
    • 0032702799 scopus 로고    scopus 로고
    • Evidence for an astrocytic glutamate transporter deficit in hepatic encephalopathy
    • Chan, H., and Butterworth, R.F. (1999). Evidence for an astrocytic glutamate transporter deficit in hepatic encephalopathy. Neurochem. Res. 24:1397-1401.
    • (1999) Neurochem. Res. , vol.24 , pp. 1397-1401
    • Chan, H.1    Butterworth, R.F.2
  • 8
    • 0034257046 scopus 로고    scopus 로고
    • Effects of ammonia on glutamate transporter (GLAST) protein and mRNA in cultured rat cortical astrocytes
    • Chan, H., Hazell, A.S., Desjardins, P., and Butterworth, R.F. (2000). Effects of ammonia on glutamate transporter (GLAST) protein and mRNA in cultured rat cortical astrocytes. Neurochem. Int. 37:243-248.
    • (2000) Neurochem. Int. , vol.37 , pp. 243-248
    • Chan, H.1    Hazell, A.S.2    Desjardins, P.3    Butterworth, R.F.4
  • 9
    • 0028594044 scopus 로고
    • N-acetylglutamate synthetase (NAGS) deficiency
    • Colombo, J.P. (1994). N-acetylglutamate synthetase (NAGS) deficiency. Adv. Exp. Med. Biol. 368:135-143.
    • (1994) Adv. Exp. Med. Biol. , vol.368 , pp. 135-143
    • Colombo, J.P.1
  • 10
    • 0027335587 scopus 로고
    • Binding of the ligand [3H]MK-801 to the MK-801 binding site of N-methyl-D-aspartate receptor during experimental encephalopathy from acute liver failure and from acute hyperammonemia in the rabbit
    • De Knegt, R.J., Kornhuber, J., Schalm, S.W., Rusche, K., Riederer, P., and Tan, J. (1993). Binding of the ligand [3H]MK-801 to the MK-801 binding site of N-methyl-D-aspartate receptor during experimental encephalopathy from acute liver failure and from acute hyperammonemia in the rabbit. Metab. Brain Dis. 8: 81-94.
    • (1993) Metab. Brain Dis. , vol.8 , pp. 81-94
    • De Knegt, R.J.1    Kornhuber, J.2    Schalm, S.W.3    Rusche, K.4    Riederer, P.5    Tan, J.6
  • 11
    • 0028139971 scopus 로고
    • Extracellular brain glutamate during acute liver failure and during acute hyperammonemia simulating acute liver failure
    • De Knegt, R.J., Schalm, S.W., van der Rijt, C.C.D., Fekkes, D., Dalm, E., and Hekking-Weyma, I. (1994). Extracellular brain glutamate during acute liver failure and during acute hyperammonemia simulating acute liver failure. J. Hepatol. 20:19-26.
    • (1994) J. Hepatol. , vol.20 , pp. 19-26
    • De Knegt, R.J.1    Schalm, S.W.2    Van der Rijt, C.C.D.3    Fekkes, D.4    Dalm, E.5    Hekking-Weyma, I.6
  • 12
    • 0026673536 scopus 로고
    • Amino acid neurotransmitter receptor changes in cerebral cortex in alcoholism: Effects of cirrhosis of the liver
    • Dodd, P.R., Thomas, G.J., Harper, C.G., and Kril, J.J. (1992). Amino acid neurotransmitter receptor changes in cerebral cortex in alcoholism: Effects of cirrhosis of the liver. J. Neurochem. 59:1506-1515.
    • (1992) J. Neurochem. , vol.59 , pp. 1506-1515
    • Dodd, P.R.1    Thomas, G.J.2    Harper, C.G.3    Kril, J.J.4
  • 13
    • 0023269882 scopus 로고
    • Ammonia-induced release of neurotransmitters from rat brain synaptosomes: Differences between the effects of amines and amino acids
    • Erecinska, M., Pastuszko, A., Wilson, D.F., and Nelson, D. (1987). Ammonia-induced release of neurotransmitters from rat brain synaptosomes: Differences between the effects of amines and amino acids. J. Neurochem. 49:1258-1265.
    • (1987) J. Neurochem. , vol.49 , pp. 1258-1265
    • Erecinska, M.1    Pastuszko, A.2    Wilson, D.F.3    Nelson, D.4
  • 14
    • 0025101819 scopus 로고
    • Neurochemical and electrophysiological studies on the inhibitory effect of ammonium ions on synaptic transmission in slices of rat hippocampus: Evidence for a post-synaptic action
    • Fan, P., Lavoie, J., Le, N.L.O., Szerb, J.C., and Butterworth, R.F. (1990). Neurochemical and electrophysiological studies on the inhibitory effect of ammonium ions on synaptic transmission in slices of rat hippocampus: Evidence for a post-synaptic action. Neuroscience 37:327-334.
    • (1990) Neuroscience , vol.37 , pp. 327-334
    • Fan, P.1    Lavoie, J.2    Le, N.L.O.3    Szerb, J.C.4    Butterworth, R.F.5
  • 15
    • 0027787443 scopus 로고
    • Effects of ammonium ions on synaptic transmission and on responses to quisqualate and N-methyl-D-aspartate in hippocampal CAI pyramidal neurons in vitro
    • Fan, P., and Szerb, J.C. (1993). Effects of ammonium ions on synaptic transmission and on responses to quisqualate and N-methyl-D-aspartate in hippocampal CAI pyramidal neurons in vitro. Brain Res. 632:225-231.
    • (1993) Brain Res. , vol.632 , pp. 225-231
    • Fan, P.1    Szerb, J.C.2
  • 16
    • 0021173149 scopus 로고
    • Extra- and intracellular amino acids in the hippocampus during development of hepatic encephalopathy
    • Hamberger, A., and Nyström, B. (1984). Extra- and intracellular amino acids in the hippocampus during development of hepatic encephalopathy. Neurochem. Res. 9:1181-1192.
    • (1984) Neurochem. Res. , vol.9 , pp. 1181-1192
    • Hamberger, A.1    Nyström, B.2
  • 18
    • 0032430914 scopus 로고    scopus 로고
    • Chronic hyperammonemia impairs glutamate-nitric oxide-cyclic GMP pathway in cerebellar neurons in culture and in the rat in vivo
    • Hermenegildo, C., Montoliu, C., Llansola, M., Muñoz, M.D., Gaztelu, J.M., Miñana, M.D., et al. (1998). Chronic hyperammonemia impairs glutamate-nitric oxide-cyclic GMP pathway in cerebellar neurons in culture and in the rat in vivo. Eur. J. Neurosci. 10:3201-3209.
    • (1998) Eur. J. Neurosci. , vol.10 , pp. 3201-3209
    • Hermenegildo, C.1    Montoliu, C.2    Llansola, M.3    Muñoz, M.D.4    Gaztelu, J.M.5    Miñana, M.D.6
  • 19
    • 0033993867 scopus 로고    scopus 로고
    • Activation of NMDA receptors in rat brain in vivo following acute ammonia intoxication. Characterization by in vivo brain microdialysis
    • Hermenegildo, C., Monfort, P., and Felipo, V. (2000). Activation of NMDA receptors in rat brain in vivo following acute ammonia intoxication. Characterization by in vivo brain microdialysis. Hepatology 31:709-715.
    • (2000) Hepatology , vol.31 , pp. 709-715
    • Hermenegildo, C.1    Monfort, P.2    Felipo, V.3
  • 20
    • 0025827552 scopus 로고
    • 3H]D-aspartate from hippocampal slice distinguishes encephalopathy related to acute liver failure from that induced by simple hyperammonemia
    • 3H]D-aspartate from hippocampal slice distinguishes encephalopathy related to acute liver failure from that induced by simple hyperammonemia. Brain Res. 567:165-168.
    • (1991) Brain Res. , vol.567 , pp. 165-168
    • Hilgier, W.1    Haugvicova, R.2    Albrecht, J.3
  • 21
    • 0344938208 scopus 로고    scopus 로고
    • Changes in extracellular profiles of neuroactive amino acids in rat striatum at the asymptomatic stage of hepatic encephalopathy
    • Hilgier, W., Zielinska, M., Borkowska, H.D., Gadamski, R., Oja, R., Saransaari, P., et al. (1999). Changes in extracellular profiles of neuroactive amino acids in rat striatum at the asymptomatic stage of hepatic encephalopathy. J. Neurosci. Res. 56:76-84.
    • (1999) J. Neurosci. Res. , vol.56 , pp. 76-84
    • Hilgier, W.1    Zielinska, M.2    Borkowska, H.D.3    Gadamski, R.4    Oja, R.5    Saransaari, P.6
  • 22
    • 0032578048 scopus 로고    scopus 로고
    • Characterization of N-methyl-D-aspartate receptors in the hyperammonemic sparse fur mouse
    • Hopkins, K.J., and Oster-Granite, M.L. (1998). Characterization of N-methyl-D-aspartate receptors in the hyperammonemic sparse fur mouse. Brain Res. 797:209-217.
    • (1998) Brain Res. , vol.797 , pp. 209-217
    • Hopkins, K.J.1    Oster-Granite, M.L.2
  • 23
    • 0027988722 scopus 로고
    • Brain ATP depletion induced by acute ammonia intoxication in rats is mediated by activation of the NMDA receptor and of Na/K-ATPase
    • Kosenko, E., Kaminsky, Y., Grau, E., Miñana, M.D., Marcaida, G., Grisolía, S., et al. (1994). Brain ATP depletion induced by acute ammonia intoxication in rats is mediated by activation of the NMDA receptor and of Na/K-ATPase. J. Neurochem. 63:2172-2178.
    • (1994) J. Neurochem. , vol.63 , pp. 2172-2178
    • Kosenko, E.1    Kaminsky, Y.2    Grau, E.3    Miñana, M.D.4    Marcaida, G.5    Grisolía, S.6
  • 24
    • 0027205354 scopus 로고
    • +-dependent binding of glutamate in rat cortical and hippocampal synaptic membranes
    • +-dependent binding of glutamate in rat cortical and hippocampal synaptic membranes. Neurosci. Lett. 158:113-116.
    • (1993) Neurosci. Lett. , vol.158 , pp. 113-116
    • Lisy, V.1    Stastny, F.2
  • 25
    • 0028169406 scopus 로고
    • Ammonium acetate inhibits ionotropic receptors and differentially affects metabotropic receptors for glutamate
    • Lombardi, G., Mannaioni, G., Leonardi, P., Cherici, G., Carla, V., and Moroni, F. (1994). Ammonium acetate inhibits ionotropic receptors and differentially affects metabotropic receptors for glutamate. J. Neural Transm. Gen. Sect. 97:187-196.
    • (1994) J. Neural Transm. Gen. Sect. , vol.97 , pp. 187-196
    • Lombardi, G.1    Mannaioni, G.2    Leonardi, P.3    Cherici, G.4    Carla, V.5    Moroni, F.6
  • 26
    • 0025924290 scopus 로고
    • 3H]amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid binding in a spontaneous canine model of chronic hepatic encephalopathy
    • 3H]amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid binding in a spontaneous canine model of chronic hepatic encephalopathy. J. Neurochem. 56:1881-1888.
    • (1991) J. Neurochem. , vol.56 , pp. 1881-1888
    • Maddison, J.E.1    Watson, W.E.J.2    Dodd, P.R.3    Johnston, G.A.R.4
  • 28
    • 0026628285 scopus 로고
    • CNQX binding to non-NMDA glutamate receptors in canine cerebro-cortical crude synaptosomal membranes: Pharmacological characterization and comparison of binding parameters in dogs with congenital portosystemic encephalopathy and control dogs
    • Maddison, J.E., Watson, W.E.J., and Johnston, G.A.R. (1992). CNQX binding to non-NMDA glutamate receptors in canine cerebro-cortical crude synaptosomal membranes: Pharmacological characterization and comparison of binding parameters in dogs with congenital portosystemic encephalopathy and control dogs. Metab. Brain Dis. 7:35-44.
    • (1992) Metab. Brain Dis. , vol.7 , pp. 35-44
    • Maddison, J.E.1    Watson, W.E.J.2    Johnston, G.A.R.3
  • 30
    • 0026512056 scopus 로고
    • Acute ammonia toxicity is mediated by the NMDA type of glutamate receptors
    • Marcaida, G., Felipo, V., Hermenegildo, C., Miñana, M.D., and Grisolía, S. (1992). Acute ammonia toxicity is mediated by the NMDA type of glutamate receptors. FEBS Lett. 296:67-68.
    • (1992) FEBS Lett. , vol.296 , pp. 67-68
    • Marcaida, G.1    Felipo, V.2    Hermenegildo, C.3    Miñana, M.D.4    Grisolía, S.5
  • 31
    • 0028881103 scopus 로고
    • Ammonia prevents activation of NMDA receptors by glutamate in rat cerebellar neuronal cultures
    • Marcaida, G., Miñana, M.D., Burgal, M., Grisolía, S., and Felipo, V. (1995). Ammonia prevents activation of NMDA receptors by glutamate in rat cerebellar neuronal cultures. Eur. J. Neurosci. 7:2389-2396.
    • (1995) Eur. J. Neurosci. , vol.7 , pp. 2389-2396
    • Marcaida, G.1    Miñana, M.D.2    Burgal, M.3    Grisolía, S.4    Felipo, V.5
  • 32
    • 0030469920 scopus 로고    scopus 로고
    • Flumazenil does not affect the increase in rat hippocampal extracellular glutamate concentration produced during thioacetamide-induced hepatic encephalopathy
    • McArdle, P., Penning, D.H., Dexter, F., and Reynolds, J.D. (1996). Flumazenil does not affect the increase in rat hippocampal extracellular glutamate concentration produced during thioacetamide-induced hepatic encephalopathy. Metab. Brain Dis. 11:329-342.
    • (1996) Metab. Brain Dis. , vol.11 , pp. 329-342
    • McArdle, P.1    Penning, D.H.2    Dexter, F.3    Reynolds, J.D.4
  • 33
    • 0021856540 scopus 로고
    • Pathologic concentrations of ammonium ions block 1-glutamate uptake
    • Mena, E.E., and Cotman, C.W. (1985). Pathologic concentrations of ammonium ions block 1-glutamate uptake. Exp. Neurol. 89:259-263.
    • (1985) Exp. Neurol. , vol.89 , pp. 259-263
    • Mena, E.E.1    Cotman, C.W.2
  • 34
    • 0031043835 scopus 로고    scopus 로고
    • Selective loss of binding sites for the glutamate receptor ligands [3H]kainate and (S)-[3H]5-fluorowillardiine in the brains of rats with acute liver failure
    • Michalak, A., and Butterworth, R.F. (1997). Selective loss of binding sites for the glutamate receptor ligands [3H]kainate and (S)-[3H]5-fluorowillardiine in the brains of rats with acute liver failure. Hepatology 25:631-635.
    • (1997) Hepatology , vol.25 , pp. 631-635
    • Michalak, A.1    Butterworth, R.F.2
  • 35
    • 0029810139 scopus 로고    scopus 로고
    • Neuroactive amino acids and glutamate (NMDA) receptors in frontal cortex of rats with experimental acute liver failure
    • Michalak, A., Rose, C., Butterworth, J., and Butterworth, R.F. (1996). Neuroactive amino acids and glutamate (NMDA) receptors in frontal cortex of rats with experimental acute liver failure. Hepatology 24:908-913.
    • (1996) Hepatology , vol.24 , pp. 908-913
    • Michalak, A.1    Rose, C.2    Butterworth, J.3    Butterworth, R.F.4
  • 36
    • 0029066242 scopus 로고
    • Prenatal exposure of rats to ammonia impairs NMDA receptor function and affords delayed protection against ammonia toxicity and glutamate neurotoxicity
    • Miñana, M.D., Marcaida, G., Grisolía, S., and Felipo, V. (1995). Prenatal exposure of rats to ammonia impairs NMDA receptor function and affords delayed protection against ammonia toxicity and glutamate neurotoxicity. J. Neuropathol. Exp. Neurol. 54:644-650.
    • (1995) J. Neuropathol. Exp. Neurol. , vol.54 , pp. 644-650
    • Miñana, M.D.1    Marcaida, G.2    Grisolía, S.3    Felipo, V.4
  • 37
    • 0030782985 scopus 로고    scopus 로고
    • Glutamate and muscarinic receptors in the molecular mechanism of acute ammonia toxicity and of its prevention
    • Miñana, M.D., Llansola, M., Hermenegildo, C., Cucarella, C., Montoliu, C., Grisolía, S., et al. (1997). Glutamate and muscarinic receptors in the molecular mechanism of acute ammonia toxicity and of its prevention. Adv. Exp. Med. Biol. 420:45-56.
    • (1997) Adv. Exp. Med. Biol. , vol.420 , pp. 45-56
    • Miñana, M.D.1    Llansola, M.2    Hermenegildo, C.3    Cucarella, C.4    Montoliu, C.5    Grisolía, S.6
  • 38
    • 0034256942 scopus 로고    scopus 로고
    • Differential effects of acute and chronic hyperammonemia on signal transduction pathways associated to NMDA receptors
    • Monfort, P., Montoliu, C., Hermenegildo, C., Muñoz, M.D., and Felipo, V. (2000). Differential effects of acute and chronic hyperammonemia on signal transduction pathways associated to NMDA receptors. Neurochem. Int. 37:249-253.
    • (2000) Neurochem. Int. , vol.37 , pp. 249-253
    • Monfort, P.1    Montoliu, C.2    Hermenegildo, C.3    Muñoz, M.D.4    Felipo, V.5
  • 39
    • 0035799999 scopus 로고    scopus 로고
    • Altered content and modulation of soluble guanylate cyclase in the cerebellum of rats with portacaval anastomosis
    • Monfort, P., Corbalán, R., Martinez, L., López-Talavera, J.C., Córdoba, J., and Felipo, V. (2001). Altered content and modulation of soluble guanylate cyclase in the cerebellum of rats with portacaval anastomosis. Neuroscience 104:1127-1139.
    • (2001) Neuroscience , vol.104 , pp. 1127-1139
    • Monfort, P.1    Corbalán, R.2    Martinez, L.3    López-Talavera, J.C.4    Córdoba, J.5    Felipo, V.6
  • 40
    • 0020681435 scopus 로고
    • The release and neosynthesis of glutamic acid are increased in experimental models of hepatic encephalopathy
    • Moroni, F., Lombardi, G., Moneti, G., and Cortesini, C. (1983). The release and neosynthesis of glutamic acid are increased in experimental models of hepatic encephalopathy. J. Neurochem. 40:850-854.
    • (1983) J. Neurochem. , vol.40 , pp. 850-854
    • Moroni, F.1    Lombardi, G.2    Moneti, G.3    Cortesini, C.4
  • 41
    • 0021187612 scopus 로고
    • Neurological outcome in children with inborn errors of urea synthesis. Outcome of urea cycle enzymopathies
    • Msall, M., Batshaw, M.L., Suss, R., Brusilow, S.W., and Mellits, E.D. (1984). Neurological outcome in children with inborn errors of urea synthesis. Outcome of urea cycle enzymopathies. N. Engl. J. Med. 310:1500-1505.
    • (1984) N. Engl. J. Med. , vol.310 , pp. 1500-1505
    • Msall, M.1    Batshaw, M.L.2    Suss, R.3    Brusilow, S.W.4    Mellits, E.D.5
  • 42
    • 0342313714 scopus 로고    scopus 로고
    • Hyperammonemia impairs NMDA receptor-dependent long-term potentiation in the CA1 of rat hippocampus in vitro
    • Muñoz, M.D., Monfort, P., Gaztelu, J.M., and Felipo, V. (2000). Hyperammonemia impairs NMDA receptor-dependent long-term potentiation in the CA1 of rat hippocampus in vitro. Neurochem. Res. 25:437-441.
    • (2000) Neurochem. Res. , vol.25 , pp. 437-441
    • Muñoz, M.D.1    Monfort, P.2    Gaztelu, J.M.3    Felipo, V.4
  • 43
    • 0031238547 scopus 로고    scopus 로고
    • The glial glutamate transporter in hyperammonemia and hepatic encephalopathy: Relation to energy metabolism and glutamatergic neurotransmission
    • Norenberg, M.D., Huo, Z., Neary, J.T., and Roig-Cantesano, A. (1997). The glial glutamate transporter in hyperammonemia and hepatic encephalopathy: Relation to energy metabolism and glutamatergic neurotransmission. Glia 21:124-131.
    • (1997) Glia , vol.21 , pp. 124-131
    • Norenberg, M.D.1    Huo, Z.2    Neary, J.T.3    Roig-Cantesano, A.4
  • 45
    • 0032978522 scopus 로고    scopus 로고
    • Reduction in MK-801 binding sites of the NMDA sub-type of glutamate receptor in a mouse model of congenital hyperammonemia: Prevention by acetyl-L-carnitien
    • Rao, K.V.R., and Qureshi, I.A. (1999). Reduction in MK-801 binding sites of the NMDA sub-type of glutamate receptor in a mouse model of congenital hyperammonemia: Prevention by acetyl-L-carnitien. Neuropharmacology 38:383-394.
    • (1999) Neuropharmacology , vol.38 , pp. 383-394
    • Rao, K.V.R.1    Qureshi, I.A.2
  • 46
    • 0025900872 scopus 로고
    • Ammonia-induced alterations in glutamate and muscimol binding to cerebellar synaptic membranes
    • Rao, V.L.R., Agrawal, A.K., and Murthy, C.R.K. (1991). Ammonia-induced alterations in glutamate and muscimol binding to cerebellar synaptic membranes. Neurosci. Lett. 130:251-254.
    • (1991) Neurosci. Lett. , vol.130 , pp. 251-254
    • Rao, V.L.R.1    Agrawal, A.K.2    Murthy, C.R.K.3
  • 47
    • 0029096856 scopus 로고
    • Selective alterations of extracellular brain amino acids in relation to function in experimental portal-systemic encephalopathy: Results of an in vivo microdialysis study
    • Rao, V.L.R., Audet, R.M., and Butterworth, R.F. (1995). Selective alterations of extracellular brain amino acids in relation to function in experimental portal-systemic encephalopathy: Results of an in vivo microdialysis study. J. Neurochem. 65:1221-1228.
    • (1995) J. Neurochem. , vol.65 , pp. 1221-1228
    • Rao, V.L.R.1    Audet, R.M.2    Butterworth, R.F.3
  • 50
    • 0001386636 scopus 로고    scopus 로고
    • Sleep alterations in hepatic encephalopathy could be due to chronic hyperammonemia
    • Romero-Vives, M., Barrenechea, C., Insausti, R., Felipo, V., and Gaztelu, J.M. (1998). Sleep alterations in hepatic encephalopathy could be due to chronic hyperammonemia. J. Sleep Res. 7(Suppl. 2):228.
    • (1998) J. Sleep Res. , vol.7 , Issue.SUPPL. 2 , pp. 228
    • Romero-Vives, M.1    Barrenechea, C.2    Insausti, R.3    Felipo, V.4    Gaztelu, J.M.5
  • 51
    • 0034102769 scopus 로고    scopus 로고
    • Mild hypothermia delays the onset of coma and prevents brain edema and extracellular brain glutamate accumulation in rats with acute liver failure
    • Rose, C., Michalak, A., Pannunzio, M., Chatauret, N., Rambaldi, A., and Butterworth, R.F. (2000). Mild hypothermia delays the onset of coma and prevents brain edema and extracellular brain glutamate accumulation in rats with acute liver failure. Hepatology 31:872-877.
    • (2000) Hepatology , vol.31 , pp. 872-877
    • Rose, C.1    Michalak, A.2    Pannunzio, M.3    Chatauret, N.4    Rambaldi, A.5    Butterworth, R.F.6
  • 52
    • 0345201620 scopus 로고    scopus 로고
    • Chronic exposure to ammonia alters pathways modulating phosphorylation of the microtubule-associated protein MAP-2 in cerebellar neurons in culture
    • Sáez, R., Llansola, M., and Felipo, V. (1999). Chronic exposure to ammonia alters pathways modulating phosphorylation of the microtubule-associated protein MAP-2 in cerebellar neurons in culture. J. Neurochem. 73:2555-2562.
    • (1999) J. Neurochem. , vol.73 , pp. 2555-2562
    • Sáez, R.1    Llansola, M.2    Felipo, V.3
  • 53
    • 0031460406 scopus 로고    scopus 로고
    • Effects of thioacetamide-induced hepatic failure on the N-methyl-D-aspartate receptor complex in the rat cerebral cortex, striatum and hippocampus
    • Saransaari, P., Oja, S.S., Borkowska, H.D., Koistinaho, J., Hilgier, W., and Albrecht, J. (1997). Effects of thioacetamide-induced hepatic failure on the N-methyl-D-aspartate receptor complex in the rat cerebral cortex, striatum and hippocampus. Mol. Chem. Neuropathol. 32:179-193.
    • (1997) Mol. Chem. Neuropathol. , vol.32 , pp. 179-193
    • Saransaari, P.1    Oja, S.S.2    Borkowska, H.D.3    Koistinaho, J.4    Hilgier, W.5    Albrecht, J.6
  • 54
    • 0025079063 scopus 로고
    • Hepatic encephalopathy influences highaffinity uptake of transmitter glutamate and aspartate into the hippocampal formation
    • Schmidt, W., Wolf, G., Grüngreiff, K., Meier, M., and Reum, T. (1990). Hepatic encephalopathy influences highaffinity uptake of transmitter glutamate and aspartate into the hippocampal formation. Metab. Brain Dis. 5:19-31.
    • (1990) Metab. Brain Dis. , vol.5 , pp. 19-31
    • Schmidt, W.1    Wolf, G.2    Grüngreiff, K.3    Meier, M.4    Reum, T.5
  • 55
    • 0031578874 scopus 로고    scopus 로고
    • Modulation of AMPA receptor subunits GluR1 and GluR2/3 in the rat cerebellum in an experimental hepatic encephalopathy model
    • Suarez, I., Bodega, G., and Fernandez, B. (1997). Modulation of AMPA receptor subunits GluR1 and GluR2/3 in the rat cerebellum in an experimental hepatic encephalopathy model. Brain Res. 778:346-353.
    • (1997) Brain Res. , vol.778 , pp. 346-353
    • Suarez, I.1    Bodega, G.2    Fernandez, B.3
  • 56
    • 0034708716 scopus 로고    scopus 로고
    • Modulation of glutamate transporters (GLAST, GLT-1 and EAAC1) in the rat cerebellum following portacaval anastomosis
    • Suarez, I., Bodega, G., and Fernandez, B. (2000). Modulation of glutamate transporters (GLAST, GLT-1 and EAAC1) in the rat cerebellum following portacaval anastomosis. Brain Res. 859:293-302.
    • (2000) Brain Res. , vol.859 , pp. 293-302
    • Suarez, I.1    Bodega, G.2    Fernandez, B.3
  • 58
    • 0026712205 scopus 로고
    • Monitoring of neurotransmitter amino acids by mean of an indwelling cisterna magna catheter: A comparison of two rodent models of fulminant liver failure
    • Swain, M.S., Bergeron, M., Audet, R., Blei, A.T., and Butterworth, R.F. (1992). Monitoring of neurotransmitter amino acids by mean of an indwelling cisterna magna catheter: A comparison of two rodent models of fulminant liver failure. Hepatology 16:1028-1035.
    • (1992) Hepatology , vol.16 , pp. 1028-1035
    • Swain, M.S.1    Bergeron, M.2    Audet, R.3    Blei, A.T.4    Butterworth, R.F.5
  • 59
    • 0025942897 scopus 로고
    • Cerebrospinal fluid amino acids in relation to neurological status in experimental portal-systemic encephalopathy
    • Therrien, G., and Butterworth, R.F. (1991). Cerebrospinal fluid amino acids in relation to neurological status in experimental portal-systemic encephalopathy. Metab. Brain Dis. 6:65-74.
    • (1991) Metab. Brain Dis. , vol.6 , pp. 65-74
    • Therrien, G.1    Butterworth, R.F.2
  • 60
    • 0020568752 scopus 로고
    • Brain amino acids measured by intracerebral dialysis in portacaval shunted rats
    • Tossman, U., Eriksson, S., Delin, A., Hagenfeldt, L., Law, D., and Ungerstedt, U. (1983). Brain amino acids measured by intracerebral dialysis in portacaval shunted rats. J. Neurochem. 41:1046-1051.
    • (1983) J. Neurochem. , vol.41 , pp. 1046-1051
    • Tossman, U.1    Eriksson, S.2    Delin, A.3    Hagenfeldt, L.4    Law, D.5    Ungerstedt, U.6
  • 61
    • 0023115093 scopus 로고
    • Brain cortical amino acids measured by intracerebral dialysis in portacaval shunted rats
    • Tossman, U., Delin, A., Eriksson, S., and Ungerstedt, U. (1987). Brain cortical amino acids measured by intracerebral dialysis in portacaval shunted rats. Neurochem. Res. 12:265-269.
    • (1987) Neurochem. Res. , vol.12 , pp. 265-269
    • Tossman, U.1    Delin, A.2    Eriksson, S.3    Ungerstedt, U.4
  • 62
    • 0030990406 scopus 로고    scopus 로고
    • Memantine, a noncompetitive NMDA receptor antagonist improves hyperammonemia-induced encephalopathy and acute hepatic encephalopathy in rats
    • Vogels, B.A.P.M., Maas, M. A. W., Daalhuisen, J., Quack, G., and Chamuleau, R. F. M. (1997). Memantine, a noncompetitive NMDA receptor antagonist improves hyperammonemia-induced encephalopathy and acute hepatic encephalopathy in rats. Hepatology 25:820-827.
    • (1997) Hepatology , vol.25 , pp. 820-827
    • Vogels, B.A.P.M.1    Maas, M.A.W.2    Daalhuisen, J.3    Quack, G.4    Chamuleau, R.F.M.5
  • 63
    • 0021178132 scopus 로고
    • Glutamic acid and glutamine levels in serum and cerebrospinal fluid in hepatic encephalopathy
    • Watanabe, A., Takei, N., Shiota, T., Nakatsukasa, H., Fujiwara, M., Sakata, T., et al. (1984). Glutamic acid and glutamine levels in serum and cerebrospinal fluid in hepatic encephalopathy. Biochem. Med. 32:225-231.
    • (1984) Biochem. Med. , vol.32 , pp. 225-231
    • Watanabe, A.1    Takei, N.2    Shiota, T.3    Nakatsukasa, H.4    Fujiwara, M.5    Sakata, T.6


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