Effects of thioacetamide-induced hepatic failure on the N-methyl-D-aspartate receptor complex in the rat cerebral cortex, striatum, and hippocampus: Binding of different ligands and expression of receptor subunit mRNAs

Molecular and Chemical Neuropathology

Volumn 32, Issue 1-3, 1997, Pages 179-193

  Saransaari, Pirjo ^a   Oja, Simo S ^a,b   Borkowska, Hanna D ^a,c   Koistinaho, Jari ^a,d   Hilgier, Wojciech ^c   Albrecht, Jan ^c  

^a UNIVERSITY OF TAMPERE MEDICAL SCHOOL   (Finland)

^b TAMPERE UNIVERSITY HOSPITAL   (Finland)

^c MOSSAKOWSKI MEDICAL RESEARCH CENTRE   (Poland)

^d UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

Hepatic encephalopathy; In situ hybridization; Ligand binding; N methyl D aspartate receptors; Thioacetamide

Indexed keywords

DIZOCILPINE; GLUTAMIC ACID; GLYCINE; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PIPERIDINE DERIVATIVE; RECEPTOR SUBUNIT; THIOACETAMIDE;

ANIMAL EXPERIMENT; ARTICLE; BINDING SITE; BRAIN CORTEX; CONTROLLED STUDY; CORPUS STRIATUM; HEPATIC ENCEPHALOPATHY; HIPPOCAMPUS; ISOTOPE LABELING; LIGAND BINDING; LIVER FAILURE; MALE; NERVE CELL MEMBRANE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; BRAIN CHEMISTRY; CEREBRAL CORTEX; HEPATITIS, TOXIC; HIPPOCAMPUS; IN SITU HYBRIDIZATION; KINETICS; LIGANDS; MALE; MEMBRANES; NEOSTRIATUM; RATS; RATS, WISTAR; RECEPTORS, N-METHYL-D-ASPARTATE; RNA, MESSENGER; THIOACETAMIDE;

ANIMALIA;

EID: 0031460406     PISSN: 10447393     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02815175     Document Type: Article

References (44)

1. Albrecht J. (1996) Astrocytes and ammonia neurotoxicity, in The Role of Glia in Neurotoxicity (Aschner, M. and Kimelberg, H.K., eds.), CRC, Boca Raton, pp. 137-153.
2. Albrecht J. and Hilgier W. (1984) Brain carbonic anhydrase activity in rats in experimental hepatogenic encephalopathy. Neurosci. Lett. 45, 7-10.
3. Aniksztejn L., Otani S., and Ben-Ari Y. (1992) Quisqualate metabotropic receptors modulate NMDA currents and facilitate induction of long-term potentiation through protein kinase C. Eur. J. Neurosci. 4, 500-505.
4. Ben-Ari Y., Aniksztejn L., and Bregestovski P. (1992) Protein kinase C modulation of NMDA currents: an important link for LTP induction. Trends Neurosci. 15, 333-339.
5. Bresink I., Danysz W., Parsons C. G., and Mutschler E. (1995) Different binding affinities of NMDA receptor channel blockers in various brain regions - indication of NMDA receptor heterogeneity. Neuropharmacology 34, 533-540.
6. Cooper A. J. L. and Plum F. (1987) Biochemistry and physiology of brain ammonia. Physiol. Rev. 67, 440-519.
7. 3H]MK-801 to the MK-801 binding site of the N-methyl-D-aspartate receptor during experimental encephalopathy from acute liver failure and from acute hyperammonemia in the rabbit. Metab. Brain Dis. 8, 81-94.
8. Dodd P. R., Thomas G. J., Harper C. G., and Kril J. J. (1992) Amino acid neurotransmitter receptor changes in cerebral cortex in alcoholism: effect of cirrhosis of the liver. J. Neurochem. 59, 1506-1515.
9. Hilgier W. and Olson J. E. (1994) Brain ion and amino acid contents during edema development in hepatic encephalopathy. J. Neurochem. 62, 197-204.
10. 3H]-deoxyglucose. Acta Neurol. Scand. 83, 353-355.
11. 3H]D-aspartate from hippocampal slices distinguishes encephalopathy related to acute liver failure from that induced by simple hyperammonemia. Brain Res. 567, 165-168.
12. Hilgier W., Zitting A., and Albrecht J. (1985) The brain octopamine and phenylethanolamine content in rats in thioacetamide-induced hepatogenic encephalopathy. Acta Neurol. Scand. 71, 195-198.
13. Hood W. F., Compton R. P., and Monahan J. B. (1989) D-Cycloserine: a ligand for the N-methyl-D-aspartate coupled glycine receptor has partial agonist characteristics. Neurosci. Lett. 98, 91-95.
14. Ishii T., Moriyoshi K., Sugihara H., Sakurada K., Kadotani H., Yokoi M., Akazawa, C., Shigemoto R., Mizuno N., Masu M., and Nakanishi S. (1993) Molecular characterization of the family of the N-methyl-D-aspartate receptor subunits. J. Biol. Chem. 268, 2836-2843.
15. Kamphuis W., Hendriksen H., Diegenbach P. C., and Lopes da Silva F. H. (1995) N-Methyl-D-aspartate and kainate receptor gene expression in hippocampal pyramidal and granular neurons in the kindling model of epileptogenesis. Neuroscience 67, 551-559.
16. Kemp J. A., Foster A. C., and Wong E. H. (1987) Non-competitive antagonists of excitatory amino acid receptors. Trends Neurosci. 10, 294-299.
17. Kessler M., Terramani T., Lynch G., and Baudry M. (1989) A glycine site associated with N-methyl-D-aspartic acid receptors: characterization and identification of a new class of antagonists. J. Neurochem. 52, 1319-1328.
18. Kraus J. E., Yeh G. C., Bonhaus D. W., Nadler J. V., and McNamara J. O. (1994) Kindling induces the long-lasting expression of a novel population of NMDA receptors in hippocampal region CA3. J. Neurosci. 14, 4196-4205.
19. Krieger C., Wagey R., Lanius R. A., and Shaw C. A. (1993) Activation of PKC reverses apparent NMDA receptor reduction in ALS. NeuroReport 4, 931-934.
20. 3H]amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid binding in a spontaneous canine model of chronic hepatic encephalopathy. J. Neurochem. 56, 1881-1888.
21. Monyer H., Sprengel R., Schoepfer R., Herb A., Higuchi M., Lomeli H., Burnashev N., Sakmann B., and Seeburg P. H. (1992) Heteromeric NMDA receptors: molecular and functional distinction of subtypes. Science 256, 1217-1221.
22. Neider J. A. and Mead R. A. (1965) Simplex method for function minimization. J. Comput. 7, 308-313.
23. 3H]glycine to synaptic membranes in rat brain, treated with Triton X-100. Neuropharmacology 28, 1263-1270.
24. Ogita K., Enomoto R., Nakahara F., Ishitsubo N., and Yoneda Y. (1995) A possible role of glutathione as an endogenous agonist at the N-methyl-D-aspartate recognition domain in rat brain. J. Neurochem. 64, 1088-1096.
25. Peeling J., Shoemaker L., Gauthier T., Benarroch A., Sutherland G. R., and Minuk, G. Y. (1993) Cerebral metabolic and histological effects of thioacetamide-induced liver failure. Am. J. Physiol. 265, G572-G578.
26. 3H]glutamate binding sites in rat brain following portacaval anastomosis. J. Neurochem. 55, 386-390.
27. Porter R. H. P. and Greenamyre J. T. (1994) Inhibition of autoradiographic MK-801 binding by an endogenous factor. Neurosci. Lett. 169, 105-108.
28. Porter R. H. P. and Greenamyre J. T. (1995) Regional variations in the pharmacology of NMDA receptor channel blockers: implications for therapeutic potential J. Neurochem. 64, 614-623.
29. 3H]MK-801 binding in Alzheimer's disease. J. Neurochem. 53, 698-704.
30. Quirion R., DiMaggio D. A., French E. D., Contreras P. C., Shiloach J., Pert, C. B., Everist H., Pert A., and O'Donohue T. L. (1984) Evidence for an endogenous peptide ligand for the phencyclidine receptor. Peptides 5, 967-973.
31. Rao R. V. L., Agrawal A. K., and Murthy Ch. R. K. (1991) Ammonia-induced alterations in glutamate and muscimol binding to cerebellar synaptic membranes. Neurosci. Lett. 130, 251-254.
32. Reynolds I. J. (1990) Modulation of NMDA receptor responsiveness by neurotransmitters, drugs and chemical modification. Life Sci. 47, 1785-1792.
33. Rock D. M. and Macdonald R. L. (1995) Polyamine regulation of N-methyl-D-aspartate receptor channels. Annu. Rev. Pharmacol. Toxicol. 35, 463-482.
34. Saransaari P. and Oja S. S. (1993a) Phencylidine-binding sites in mouse cerebral cortex during development and ageing: effects of inhibitory amino acids. Mech. Ageing Dev. 68, 125-136.
35. Saransaari P. and Oja S. S. (1993b) Strychnine-insensitive glycine binding to cerebral cortical membranes in developing and ageing mice. Mech. Ageing Dev. 72, 57-66.
36. Saransaari P. and Oja S. S. (1995) Dizocilpine binding to cerebral cortical membranes from developing and ageing mice. Mech. Ageing Dev. 85, 171-181.
37. Schalling M., Dagerlind A., Brene S., Hallman H., Djurfeldt M., Persson H., Terenius, L., Goldstein M., Schlesinger D., and Hökfelt T. (1988) Coexistence and gene expression of phenylethanolamine N-methyl-transferase, tyrosine hydroxylase, and neuropeptide tyrosine in the rat and bovine adrenal gland: effects of reserpine. Proc. Natl. Acad. Sci. USA 85, 8306-8310.
38. Seeburg P. H. (1993) The molecular biology of mammalian glutamate receptor channels. Trends Neurosci. 16, 359-365.
39. Stastny F., Hilgier W., Albrecht J., and Lisy V. (1988) Changes in the activity of gamma-glutamyl transpeptidase in brain microvessels, astroglial cells and synaptosomes derived from rats with hepatic encephalopathy. Neurosci. Lett. 84, 323-328.
40. 3H]TCP) to the NMDA-phenycyclidine receptor complex. Neuropharmacology 28, 1-7.
41. Szerb J. C. and Butterworth R. F. (1992) Effect of ammonium ion on synaptic transmission in the mammalian central nervous system. Prog. Neurobiol. 39, 135-153.
42. Varga V., Janáky R., Saransaari P., and Oja S. S. (1994) Endogenous γ-L-glutamyl and β-L-aspartyl peptides and excitatory aminoacidergic neurotransmission in the brain. Neuropeptides 27, 19-26.
43. 2+. J. Comp. Neurol. 335, 369-380.
44. Yoneda Y. and Ogita K. (1991) Heterogeneity of the N-methyl-D-aspartate receptor ionophore complex in rat brain, as revealed by ligand binding techniques. J. Pharmacol. Exp. Ther. 259, 86-96.