Potentiation of Fas- and trail-mediated apoptosis by IFN-γ in A549 lung epithelial cells: Enhancement of caspase-8 expression through IFN-response element

Cytokine

Volumn 20, Issue 6, 2002, Pages 283-288

  Kim, Ki Bae ^a   Choi, Yun Hee ^a   Kim, In Ki ^a   Chung, Chul Woong ^a   Kim, Byung Ju ^a   Park, Yang Mi ^a   Jung, Yong Keun ^a  

^a Gwangju Institute of Science and Technology (GIST)   (South Korea)

Author keywords

Apoptosis; Caspase 8; Cytokines; Gene regulation; IFN

Indexed keywords

CASPASE 10; CASPASE 2; CASPASE 3; CASPASE 7; CASPASE 8; CASPASE 9; CASPASE INHIBITOR; CYTOKINE; FAS ANTIGEN; GAMMA INTERFERON; LUCIFERASE; RECEPTOR; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

APOPTOSIS; ARTICLE; CELL LINE; DNA FLANKING REGION; DNA RESPONSIVE ELEMENT; GENE ACTIVITY; GENE LOCATION; HUMAN; HUMAN CELL; LUNG ALVEOLUS EPITHELIUM; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REPORTER GENE; SENSITIZATION; UPREGULATION; WESTERN BLOTTING;

EID: 0036915360     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1006/cyto.2003.2008     Document Type: Article

References (32)

1. Meier P., Finch A., Evan G. Apoptosis in development. Nature. 407:2000;796-801.
2. Krammer P.H. CD95's deadly mission in the immune system. Nature. 407:2000;789-795.
3. Hengartner M.O. The biochemistry of apoptosis. Nature. 407:2000;770-776.
4. Ashkenazi A., Dixit V.M. Death Receptors: Signaling and Modulation. Science. 281:1998;1305-1308.
5. Thornberry N.A., Lazebnik Y. Caspases: Enemies within. Science. 281:1998;1312-1316.
6. Milligan C.E., Prevette D., Yaginuma H., Homma S., Cardwell C., Fritz L.C., Tomaselli K.J., Oppenheim R.W., Schwartz L.M. Peptide inhibitors of the ICE protease family arrest programmed cell death of motoneurons in vivo and in vitro. Neuron. 15:1995;385-393.
7. Kuida K., Zheng T.S., Na S., Kuan C.Y., Yang D., Karasuyama H., Rakic P., Flavell R.A. Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice. Nature. 384:1996;368-372.
8. Kuida K., Haydar T.F., Kuan C.Y., Gu Y., Taya C., Karasuyama H., Su M.S., Rakic P., Flavell R.A. Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9. Cell. 94:1998;325-337.
9. Nakagawa T., Zhu H., Morishima N., Li E., Xu J., Yankner B.A., Yuan J. Caspase-12 mediates endoplasmic reticulum-specific apoptosis and cytotoxicity by amyloid-β Nature. 403:2000;98-103.
10. Nicholson D.W. From bench to clinic with apoptosis-based therapeutic agents. Nature. 407:2000;810-816.
11. Vartanian T., Li Y., Zhao M., Stefansson K. Interferon-γ-induced oligodendrocyte cell death: implications for the pathogenesis of multiple sclerosis. Mol Med. 1:1995;732-743.
12. Wu A.J., Chen Z.J., Tsokos M., O'Connell B.C., Ambudkar I.S., Baum B.J. Interferon-γ induced cell death in a cultured human salivary gland cell line. J Cell Physiol. 167:1996;297-304.
13. Shustov A., Nguyen P., Finkelman F., Elkon K.B., Via C.S. Differential expression of Fas and Fas ligand in acute and chronic graft-versus-host disease: up-regulation of Fas and Fas ligand requires CD8+ T cell activation and IFN-γ production. J Immunol. 161:1998;2848-2855.
14. Wen L.P., Madani K., Fahrni J.A., Duncan S.R., Rosen G.D. Dexamethasone inhibits lung epithelial cell apoptosis induced by IFN-γ and Fas. Am J Physiol. 273:1997;L921-929.
15. Bernassola F., Scheuerpflug C., Herr I., Krammer P.H., Debatin K.M., Melino G. Induction of apoptosis by IFN-γ in human neuroblastoma cell lines through the CD95/CD95L autocrine circuit. Cell Death Differ. 6:1999;652-660.
16. Kumar A., Commane M., Flickinger T.W., Horvath C.M., Stark G.R. Defective TNF-α-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases. Science. 278:1997;1630-1632.
17. Chin Y.E., Kitagawa M., Kuida K., Flavell R.A., Fu X.Y. Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosis. Mol Cell Biol. 17:1997;5328-5337.
18. Grenet J., Teitz T., Wei T., Valentine V., Kidd V.J. Structure and chromosome localization of the human CASP8 gene. Gene. 226:1999;225-232.
19. Kuwano K., Hagimoto N., Kawasaki M., Yatomi T., Nakamura N., Nagata S., Suda T., Kunitake R., Maeyama T., Miyazaki H., Hara N. Essential roles of the Fas-Fas ligand pathway in the development of pulmonary fibrosis. J Clin Invest. 104:1999;13-19.
20. Gochuico B.R., Miranda K.M., Hessel E.M., De Bie J.J., Van Oosterhout A.J., Cruikshank W.W., Fine A. Airway epithelial Fas ligand expression: potential role in modulating bronchial inflammation. Am J Physiol. 274:1998;L444-449.
21. Watanabe-Fukunaga R., Brannan C.I., Copeland N.G., Jenkins N.A., Nagata S. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature. 356:1992;314-317.
22. Sedger L.M., Shows D.M., Blanton R.A., Peschon J.J., Goodwin R.G., Cosman D., Wiley S.R. IFN-γ mediates a novel antiviral activity through dynamic modulation of TRAIL and TRAIL receptor expression. J Immunol. 163:1999;920-926.
23. Xu X., Fu X.Y., Plate J., Chong A.S. IFN-γ induces cell growth inhibition by Fas-mediated apoptosis: requirement of STAT1 protein for up-regulation of Fas and FasL expression. Cancer Res. 58:1998;2832-2837.
24. Park S.Y., Billiar T.R., Seol D.W. IFN-gamma inhibition of TRAIL-induced IAP-2 upregulation, a possible mechanism of IFN-gamma-enhanced TRAIL-induced apoptosis. Biochem Biophys Res Commun. 22:2002;233-236.
25. Liu S., Yu Y., Zhang M., Wang W., Cao X. The involvement of TNF-α-related apoptosis inducing ligand in the enhanced cytotoxicity of IFN-β-stimulated human dendritic cells to tumor cells. J Immunol. 166:2001;5407-5415.
26. Kumar-Sinha C., Varambally S., Sreekumar A., Chinnaiyan A. Molecular cross-talk between the TRAIL and interferon signaling pathways. J Biol Chem. 277:2002;575-585.
27. Oshima K., Yanase N., Ibukiyama C., Kayagaki N., Yagita H., Mizuguchi J. Involvement of TRAIL/TRAIL/R interaction in IFN-alpha-induced apoptosis of Daudi B lymphoma cells. Cytokine. 21:2001;193-201.
28. Kim I.K., Chung C.W., Woo H.N., Hong G.S., Nagata S., Jung Y.K. Reconstitution of Caspase-8 Sensitizes JB-6 Cells to TRAIL. Biochem Biophys Res Comm. 277:2000;311-316.
29. Varfolomeev E.E., Schuchmann M., Luria V., Chinnikulchai N., Beckmann J.S., Mett I.L., Rebrikov D., Brodianski V.M., Kemper O.C., Kollet O., Lapidot T., Soffer D., Sobe T., Avraham K.B., Goncharov T., Holtmann H., Lonai P., Wallach D. Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally. Immunity. 9:1998;267-276.
30. Ruiz-Ruiz C., Munoz-Pinedo C., Lopez-Rivas A. Interferon-γ treatment elevates caspase-8 expression and sensitizes human breast cancer cells to a death receptor-induced mitochondria-operated apoptotic program. Cancer Res. 60:2000;5673-5680.
31. Dai C., Krantz S.B. Interferon-γ induces upregulation and activation of caspases 1, 3, and 8 to produce apoptosis in human erythroid progenitor cells. Blood. 93:1999;3309-3316.
32. Iwase S., Furukawa Y., Kikuchi J., Saito S., Nakamura M., Nakayama R., Horiguchi-Yamada J., Yamada H. Defective binding of IRFs to the initiator element of interleukin-1beta-converting enzyme (ICE) promoter in an interferon-resistant Daudi subline. FEBS Lett. 450:1999;263-267.