NKT and T cells: Coordinate regulation of NK-like phenotype and cytokine production

European Journal of Immunology

Volumn 32, Issue 12, 2002, Pages 3453-3462

  Loza, Matthew J ^a   Metelitsa, Leonid ^b   Perussia, Bice ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA GALACTOSYLCERAMIDE; CD161 ANTIGEN; CD1D ANTIGEN; CD56 ANTIGEN; CYTOKINE; GALACTOSYLCERAMIDE; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 4; LYMPHOCYTE ANTIGEN; MONOKINE; UNCLASSIFIED DRUG;

ANTIGEN EXPRESSION; ARTICLE; CELL MATURATION; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOKINE PRODUCTION; HUMAN; HUMAN CELL; IMMUNOMODULATION; IMMUNOREGULATION; IMMUNOTHERAPY; LYMPHOCYTE DIFFERENTIATION; NATURAL KILLER CELL; PHENOTYPE; PRIORITY JOURNAL; T LYMPHOCYTE;

ADULT; ANTIGENS, CD1; ANTIGENS, CD56; ANTIGENS, SURFACE; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELLS, CULTURED; CYTOKINES; GALACTOSYLCERAMIDES; HUMANS; INFANT, NEWBORN; INTERFERON TYPE II; INTERLEUKIN-13; INTERLEUKIN-4; KILLER CELLS, NATURAL; LECTINS, C-TYPE; PHENOTYPE; T-LYMPHOCYTE SUBSETS;

EID: 0036909989     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200212)32:12<3453::AID-IMMU3453>3.0.CO;2-D     Document Type: Article

References (40)

1. Bendelac, A., Rivera, M. N., Park, S. H. and Roark, J. H., Mouse CD1-specific NK1 T cells: development, specificity, and function. Annu. Rev. Immunol. 1997. 15: 535-562.
2. Kawano, T., Cui, J., Koezuka, Y., Toura, I., Kaneko, Y., Motoki, K., Ueno, H., Nagakawa, R., Sato, H., Koseki, H. and Taniguchi, M., CD1d-restricted and TCR-mediated activation of Valpha14 NKT cells by glycosylceramides. Science 1997. 278: 1626-1629.
3. +-like thymocytes in the NOD mouse. Eur. J. Immunol. 1996. 26: 2989-2998.
4. Sumida, T., Sakamoto, A., Murata, H., Makino, Y., Takahashi, H., Yoshida, S., Nishioka, K., Iwamoto, K. and Taniguchi, M., Selective reduction of T cells bearing invariant Valpha 24J alpha Q antigen receptor patients with systemic sclerosis. J. Exp. Med. 1995. 182: 1163-1168.
5. Singh, A. K., Wilson, M. T., Hong, S., Olivares-Villagomez, D., Du, C., Stanic, A. K., Joyce, S., Sriram, S., Koezuka, Y. and Van Kaer, L., Natural killer T cell activation protects mice against experimental autoimmune encephalomyelitis. J. Exp. Med. 2001. 194: 1801-1811.
6. Godfrey, D. I., Hammond, K. J., Poulton, L. D., Smyth, M. J. and Baxter, A. G., NKT cells: facts, functions and fallacies. Immunol. Today 2000. 21: 573-583.
7. Lanier, L. L., Chang, C. and Phillips, J. H., Human NKR-P1A. A disulfide-linked homodimer of the C-type lectin superfamily expressed by a subset of NK and T lymphocytes. J. Immunol. 1994. 153: 2417-2428.
8. + CD4-CD8- T cells. J. Exp. Med. 1997. 186: 109-120.
9. Prussin, C. and Foster, B., TCR Valpha 24 and Vbeta 11 coexpression defines a human NK1 T cell analog containing a unique Th0 subpopulation. J. Immunol. 1997. 159: 5862-5870.
10. Matsuda, J. L., Naidenko, O. V., Gapin, L., Nakayama, T., Taniguchi, M., Wang, C. R., Koezuka, Y. and Kronenberg, M., Tracking the response of natural killer T cells to a glycolipid antigen using CD1d tetramers. J. Exp. Med. 2000. 192: 741-754.
11. Norris, S., Natural T cells in the human liver: cytotoxic lymphocytes with dual T cell and natural killer cell phenotype and function are phenotypically heterogenous and include Valpha 24-Jalpha Q and gamma delta T cell receptor bearing cells. Human Immunol. 1999. 60: 20-31.
12. Phillips, J. H., Hori, T., Nagler, A., Bhat, N., Spits, H. and Lanier, L. L., Ontogeny of human natural killer (NK) cells: fetal NK cells mediate cytolytic function and express cytoplasmic CD3 epsilon, delta proteins. J. Exp. Med. 1992. 92: 1055-1066.
13. Gapin, L., Matsuda, J. L., Surh, C. D. and Kronenberg, M., NKT cells derive from double-positive thymocytes that are positively selected by CD1d. Nat. Immunol. 2001. 2: 971-978.
14. Loza, M. J. and Perussia, B., Final steps of natural killer cells maturation: a general model for type 1-type 2 differentiation? Nat. Immunol. 2001. 2: 917-924.
15. Dong, C. and Flavell, R. A., Cell fate decision: T-helper 1 and 2 subsets in immune responses. Arthritis Res. 2000. 2: 179-188.
16. Leite-De-Moares, M. C., Moreau, G., Arnould, A., Machavoine, F., Garcia, C., Papiernick, M. and Dy, M., IL-4-producing NK T cells are biased towards IFN-γ production by IL-12. Influence of the microenvironment on the functional capacities of NK T cells. Eur. J. Immunol. 1998. 28: 1507-1515.
17. Metelitsa, L. S., Naidenko, O. V., Kant, A., Wu, H.-W., Loza, M. L., Perussia, B., Kronenberg, M. and Seeger, R. C., Human NKT cells mediate antitumor cytotoxicity directly by recognizing target cell CD1d with bound ligand or indirectly by producing IL-2 to activate NK cells. J. Immunol. 2001. 167: 3114-3122.
18. + NKT lymphocytes are activated memory cells. Eur. J. Immunol. 2000. 30: 1544-1550.
19. Tarazona, R., DelaRosa, O., Alonso, C., Ostos, B., Espejo, J., Pena, J. and Solana, R., Increased expression of NK cell markers on T lymphocytes in aging and chronic activation of the immune system reflects accumulation of effector/senescent T cells. Mech. Aging Dev. 2000. 121: 77-88.
20. + NKT cells. Eur. J. Immunol. 2001. 31: 2901-2909.
21. + NK cells and regulation of their pool size by IL-4. Eur. J. Immunol. 2002. 32: 413-423.
22. Loza, M. J. and Perussia, B., Peripheral immature CD2-/Io T cell development from type 2 to type1 cytokine production. J. Immunol. 2002. 169: 3061-3068.
23. + T cells produce large amounts of IL-4 and IFN-γ upon activation by anti-CD3 or CD1. J. Immunol. 1997. 159: 2240-2249.
24. Lee, P. T., Benlagha, K., Teyton, L. and Bendelac, L., Distinct functional lineages of human Valpha 24 natural killer T cells. J. Exp. Med. 2002. 195: 637-641.
25. Gumperz, J., Miyake, S., Yamamura, T. and Brenner, M. B., Functionally distinct subsets of CD1d-restricted natural killer T cells revealed by CD1d tetramer staining. J. Exp. Med. 2002. 195: 625-636.
26. Mcnerlan, S. E., Rea, I. M., Alexander, H. D. and Morris, T. C., Changes in natural killer cells, the CD57CD8 subset, and related cytokines in healthy aging. J. Clin. Immunol. 1998. 18: 31-38.
27. + surface phenotype and a T helper1 profile of cytokine secretion in the liver of patients chronically infected with hepatitis B virus. J. Immunol. 1994. 152: 3074-3087.
28. Joyce, S., CD1d and natural T cells: how their properties jump-start the immune system. Cell. Mol. Life Sci. 2001. 58: 442-469.
29. + CD1d-dependent precursor stage. J. Exp. Med. 2002. 195: 835-844.
30. Roncarolo, M. G., Bacchetta, R., Bordignon, C., Narula, S. and Levings, M. K., Type 1 regulatory cells. Immunol. Rev. 2001. 182: 68-79.
31. Brutkiewicz, R. R. and Sriram, V., Natural killer T (NKT) cells and their role in anti-tumor immunity. Crit. Rev. Oncol. Hematol. 2002. 41: 287-298.
32. Smyth, M. J., Crowe, N. Y., Hayakawa, Y., Takeda, K., Yagita, H. and Godfrey, D. I., NKT cells- conductors of tumor immunity? Curr. Opin. Immunol. 2002. 14: 165-171.
33. Nishimura, T., Kitamura, H., Iwakabe, K., Yahata, T., Ohta, A., Sato, M., Takeda, K., Okumura, K., Van Kaer, L., Kawano, T., Taniguchi, M., Nakui, M., Sekimoto, M. and Koda, T., The interface between innate and acquired immunity: glycolipid antigen presentation by CD1d-expressing dendritic cells to NKT cells induces the differentiation of antigen-specific cytotoxic T lymphocytes. Int. Immunol. 2000. 12: 987-994.
34. Cesano, A., Visonneau, S., Jeglum, K. A., Owen, J., Wilkinson, K., Carner, K., Reese, L. and Santoli, D., Phase I clinical trial with a human major histocompatibility complex unrestricted cytotoxic T cell line (TALL-104) in dogs with advanced tumors. Cancer Res. 1996. 156: 3021-3029.
35. Kelly, J. M., Darcy, P. K., Markby, J. L., Godfrey, D. I., Takeda, K., Yagita, H. and Smyth, M. J., Induction of tumor-specific T cell memory by NK cell-mediated tumor rejection. Nat. Immunol. 2002. 3: 83-90.
36. Sharif, S., Arreaza, G. A., Zucker, P., Mi, Q. S., Sondhi, J., Naidenko, O. V., Kronenberg, M., Koezuba, ka, Y., Delovitch, T. L., Gombert, J. M., Leite-De-Moraes, M., Gouarin, C., Zhu, R., Hameg, A., Nakayama, T., Taniguchi, M., Lepaut, F., Lehuen, A., Bach, J. F. and Herbelin, A., Activation of natural killer T cells by alpha-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes. Nat. Med. 2001. 7: 1057-1062.
37. Hong, S., Wilson, M. T., Serizawa, I., Wu, L., Singh, N., Naidenko, O. V., Miura, T., Haba, T., Scherer, D. C., Kronenberg, M., Koezuka, Y. and Van Kaer, L., The natural killer T cell ligand alpha-galactosylceramide prevents autoimmune diabetes in nonobese diabetic mice. Nat. Med. 2001. 7: 1052-1056.
38. Sharif, S., Arreaza, G. A., Zucker, P. and Delovitch, T. L., Regulatory natural killer T cells protect againt spntaneous and recurrent type1 diabetes. Ann. N. Y. Acad. Sci. 2002. 958: 77-88.
39. - functionally immature human NK cell subset that differentiates in vitro in the presence of interleukin 12. J. Exp. Med. 1996. 184: 1845-1856.
40. Loza, M. J., Zamai, L., Azzoni, L., Rosati, E. and Perussia, B., Expression of type 1 (IFN-γ) and type 2 (IL-13, IL-5) cytokines at distinct stages of NK cell differentiation from progenitor cells. Blood 2002. 99: 1273-1281.