v-Ha-RaS oncogene upregulates the 92-kDa type IV collagenase (MMP-9) gene by increasing cellular superoxide production and activating NF-κB

Free Radical Biology and Medicine

Volumn 31, Issue 4, 2001, Pages 520-529

  Yang, Ji Qin ^a   Zhao, Weiling ^a   Duan, Hong ^a   Robbins, Mike E C ^a   Buettner, Garry ^a   Oberley, Larry W ^a   Domann, Frederick E ^a,b  

^a UNIVERSITY OF IOWA HOSPITALS AND CLINICS   (United States)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

Extracellular matrix; Free radicals; Metalloproteinase; Ras; Redox; Superoxide

Indexed keywords

ACETYLCYSTEINE; COLLAGEN TYPE 4; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; PLASMINOGEN ACTIVATOR INHIBITOR; RAS PROTEIN; SUPEROXIDE; TISSUE INHIBITOR OF METALLOPROTEINASE;

ANIMAL CELL; ARTICLE; BASEMENT MEMBRANE; BLOOD LEVEL; CONTROLLED STUDY; DNA BINDING; ENZYME ACTIVATION; EPITHELIUM CELL; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; GENE OVEREXPRESSION; GENETIC REGULATION; GENETIC TRANSFECTION; KIDNEY EPITHELIUM; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STEADY STATE;

ANIMALS; BLOTTING, NORTHERN; BLOTTING, WESTERN; CYTOCHROME C GROUP; DNA PRIMERS; EPITHELIAL CELLS; FIBRONECTINS; GENES, RAS; KIDNEY; MATRIX METALLOPROTEINASE 9; MOLECULAR WEIGHT; NF-KAPPA B; PLASMINOGEN ACTIVATOR INHIBITOR 1; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SUPEROXIDE DISMUTASE; SUPEROXIDES; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TRANSCRIPTION FACTOR AP-1; UP-REGULATION;

EID: 0035882461     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(01)00613-X     Document Type: Article

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