Tyrosine kinase inhibitors and signal transduction modulators: Rationale and current status as chemopreventive agents for prostate cancer

Urology

Volumn 57, Issue 4, 2001, Pages 77-80

  Bergan, Raymond C ^a   Waggle, Doyle H ^b   Carter, Stephen K ^c   Horak, Ivan ^d   Slichenmyer, William ^e   Meyers, Michael ^f  

^a NORTHWESTERN UNIVERSITY   (United States)

^b Protein Technologies International   (United States)

^c SUGEN INC   (United States)

^d Parke Davis ^*  (United States)

^e PFIZER INC   (United States)

^f SANOFI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

3 [(4,5 DIMETHYL 1H PYRROL 2 YL)METHYLENE] 1,3 DIHYDRO 2H INDOL 2 ONE; ANTINEOPLASTIC AGENT; GENISTEIN; ISOFLAVONE DERIVATIVE; LEFLUNOMIDE; PROTEIN FARNESYLTRANSFERASE INHIBITOR; PROTEIN TYROSINE KINASE INHIBITOR; PTI G 2535; PTI G 4660; UNCLASSIFIED DRUG;

CANCER PREVENTION; CELL DIFFERENTIATION; CELL GROWTH; CHEMOPROPHYLAXIS; CONFERENCE PAPER; CYTOLOGY; DRUG MECHANISM; ENZYME INHIBITION; HUMAN; PRIORITY JOURNAL; PROSTATE CANCER; SIGNAL TRANSDUCTION;

ALKYL AND ARYL TRANSFERASES; ANGIOGENESIS INHIBITORS; ANTICARCINOGENIC AGENTS; ENZYME INHIBITORS; FARNESYLTRANSTRANSFERASE; GENISTEIN; HUMANS; MALE; PROSTATIC NEOPLASMS; PROTEIN-TYROSINE KINASES; RECEPTOR, ERBB-2; SIGNAL TRANSDUCTION;

EID: 0034977872     PISSN: 00904295     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0090-4295(00)00946-8     Document Type: Article

References (12)

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10. Expression of mRNA for epidermal growth factor, transforming growth factor-alpha and their receptor in human prostate tissue and cell lines
11. Comparative analysis of mRNA and protein expression for epidermal growth factor receptor and ligands relative to the proliferative index in human prostate tissue
12. Evidence for the differential expression of a variant EGF receptor protein in human prostate cancer