Myosin light chain kinase inhibitors induce retraction of mature oligodendrocyte processes

Neurochemical Research

Volumn 27, Issue 11, 2002, Pages 1305-1312

  Thomas, María G ^a,b   Santa Coloma, Tomás A ^a   Correale, Jorge ^b   Boccaccio, Graciela L ^a,c  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b Instituto de Investigaciones Neurologicas Raul Carrera   (Argentina)

^c FUNDACIÓN INSTITUTO LELOIR   (Argentina)

Author keywords

ML 7; ML 9; MLCK; Myelin; Myosin II; Oligodendrocyte processes

Indexed keywords

MYOSIN IIA; MYOSIN LIGHT CHAIN KINASE INHIBITOR; PROTEIN ML 7; PROTEIN ML 9; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CELL ACTIVITY; CELL ADHESION; CELL CULTURE; CELL DIFFERENTIATION; CELL GROWTH; CELL MATURATION; CELL SHAPE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; MYELINATION; NONHUMAN; OLIGODENDROGLIA; PHOSPHORYLATION; PRIORITY JOURNAL; RAT;

ANIMALS; AZEPINES; ENZYME INHIBITORS; MYOSIN-LIGHT-CHAIN KINASE; NAPHTHALENES; OLIGODENDROGLIA; PHOSPHORYLATION; RATS; RATS, WISTAR;

ANIMALIA;

EID: 0036867495     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1021615530960     Document Type: Article

References (35)

1. Hardy, R. J. and Friedrich, V. L., Jr. 1996. Progressive remodeling of the oligodendrocyte process arbor during myelinogenesis. Dev. Neurosci. 18:243-254.
2. Kachar, B., Behar, T., and Dubois-Dalcq, M. 1986. Cell shape and motility of oligodendrocytes cultured without neurons. Cell Tiss. Res. 244:27-38.
3. Totsukawa, G., Yamakita, Y., Yamashiro, S., Hartshorne, D. J., Sasaki, Y., and Matsumura, F. 2000. Distinct roles of ROCK (Rho-kinase) and MLCK in spatial regulation of MLC phosphorylation for assembly of stress fibers and focal adhesions in 3T3 fibroblasts. J. Cell Biol. 150:797-806.
4. Rottner, K., Hall, A., and Small, J. V. 1999. Interplay between Rac and Rho in the control of substrate contact dynamics. Curr. Biol. 9:640-648.
5. Gillespie, G. Y., Soroceanu, L., Manning, T. J., Jr., Gladson, C. L., and Rosenfeld, S. S. 1999. Glioma migration can be blocked by nontoxic inhibitors of myosin II. Cancer Res. 59:2076-2082.
6. Sanders, L. C., Matsumura, F., Bokoch, G. M., and de Lanerolle, P. 1999. Inhibition of myosin light chain kinase by p21-activated kinase. Science 283:2083-2085.
7. Ruchhoeft, M. L. and Harris, W. A. 1997. Myosin functions in Xenopus retinal ganglion cell growth cone motility in vivo. J. Neurobiol. 32:567-578.
8. Wylie, S. R., Wu, P. J., Patel, H., and Chantler, P. D. 1998. A conventional myosin motor drives neurite outgrowth. Proc. Natl. Acad. Sci. USA 95:12967-12972.
9. Wylie, S. R. and Chantler, P. D. 2001. Separate but linked functions of conventional myosins modulate adhesion and neurite outgrowth. Nat. Cell Biol. 3:88-92.
10. Song, J., Goetz, B. D., Baas, P. W., and Duncan, I. D. 2001. Cytoskeletal reorganization during the formation of oligodendrocyte processes and branches. Mol. Cell Neurosci. 17:624-636.
11. Simpson, P. B. and Armstrong, R. C. 1999. Intracellular signals and cytoskeletal elements involved in oligodendrocyte progenitor migration. Glia 26:22-35.
12. Warrick, H. M. and Spudich, J. A. 1999. Myosin II, cytoplasmic. Pages: In Guidebook to the Cytoskeletal and Motor Proteins. (Kreis, T., and Vale, R., eds.), Oxford University, Oxford, New York.
13. Baorto, D. M., Mellado, W., and Shelanski, M. L. 1992. Astrocyte process growth induction by actin breakdown. J. Cell Biol. 117:357-367.
14. Clow, P. A., Chen, T., Chisholm, R. L., and McNally, J. G. 2000. Three-dimensional in vivo analysis of Dictyostelium mounds reveals directional sorting of prestalk cells and defines a role for the myosin II regulatory light chain in prestalk cell sorting and tip protrusion. Development 127:2715-2728.
15. 2+-dependent myosin II activation is required for uropod retraction during neutrophil migration. J. Cell Sci. 113:1287-1298.
16. Jalink, K., van Corven, E. J., Hengeveld, T., Morii, N., Narumiya, S., and Moolenaar, W. H. 1994. Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho. J. Cell Biol. 126:801-810.
17. Katoh, K., Kano, Y., Amano, M., Kaibuchi, K., and Fujiwara, K. 2001. Stress fiber organization regulated by MLCK and Rhokinase in cultured human fibroblasts. Am. J. Physiol. Cell Physiol. 280:C1669-C1679.
18. Saitoh, M., Ishikawa, T., Matsushima, S., Naka, M., and Hidaka, H. 1987. Selective inhibition of catalytic activity of smooth muscle myosin light chain kinase. J. Biol. Chem. 262:7796-7801.
19. Nagatsu, T., Suzuki, H., Kiuchi, K., Saitoh, M., and Hidaka, H. 1987. Effects of myosin light-chain kinase inhibitor on catecholamine secretion from rat pheochromocytoma PC12h cells. Biochem. Biophys. Res. Commun. 143:1045-1048.
20. Allinquant, B., Staugaitis, S. M., and Colman, D. R. 1991. The ectopic expression of myelin basic protein isoforms in Shiverer oligodendrocytes: Implications for myelinogenesis. J. Cell Biol. 113:393-403.
21. Dyer, C. A. and Benjamins, J. A. 1989. Organization of oligodendroglial membrane sheets. 1: Association of myelin basic protein and 2′,3′-cyclic nucleotide 3′-phosphohydrolase with cytoskeleton. J. Neurosci Res. 24:201-211.
22. Lunn, K. F., Baas, P. W., and Duncan, I. D. 1997. Microtubule organization and stability in the oligodendrocyte. J. Neurosci. 17:4921-4932.
23. Carson, J. H., Worboys, K., Ainger, K., and Barbarese, E. 1997. Translocation of myelin basic protein mRNA in oligodendrocytes requires microtubules and kinesin. Cell. Motil. Cytoskeleton 38:318-328.
24. Cramer, L. P. and Mitchison, T. J. 1995. Myosin is involved in postmitotic cell spreading. J. Cell Biol. 131:179-189.
25. van Leeuwen, F. N., van Delft, S., Kain, H. E., van der Kammen, R. A., and Collard, J. G. 1999. Rac regulates phosphorylation of the myosin-II heavy chain, actinomyosin disassembly and cell spreading. Nat. Cell Biol. 1:242-248.
26. Straussman, R., Even, L., and Ravid, S. 2001. Myosin II heavy chain isoforms are phosphorylated in an EGF-dependent manner: Involvement of protein kinase C. J. Cell Sci. 114:3047-3057.
27. Baron, W., Metz, B., Bansal, R., Hoekstra, D., and de Vries, H. 2000. PDGF and FGF-2 signaling in oligodendrocyte progenitor cells: Regulation of proliferation and differentiation by multiple intracellular signaling pathways. Mol. Cell Neurosci. 15:314-329.
28. Baron, W., de Jonge, J. C., de Vries, H., and Hoekstra, D. 2000. Perturbation of myelination by activation of distinct signaling pathways: An in vitro study in a myelinating culture derived from fetal rat brain. J. Neurosci. Res. 59:74-85.
29. Heinrich, M., Gorath, M., and Richter-Landsberg, C. 1999. Neurotrophin-3 (NT-3) modulates early differentiation of oligodendrocytes in rat brain cortical cultures. Glia 28:244-255.
30. Baron, W., de Vries, E. J., de Vries, H., and Hoekstra, D. 1999. Protein kinase C prevents oligodendrocyte differentiation: Modulation of actin cytoskeleton and cognate polarized membrane traffic. J. Neurobiol. 41:385-398.
31. McNulty, S., Crouch, M., Smart, D., and Rumsby, M. 2001. Differentiation of bipolar CG-4 line oligodendrocytes is associated with regulation of CREB, MAP kinase and PKC signalling pathways. Neurosci. Res. 41:217-226.
32. Dugina, V., Fontao, L., Chaponnier, C., Vasiliev, J., and Gabbiani, G. 2001. Focal adhesion features during myofibroblastic differentiation are controlled by intracellular and extracellular factors. J. Cell Sci. 114:3285-3296.
33. Folsom, T. D. and Sakaguchi, D. S. 1999. Disruption of actin-myosin interactions results in the inhibition of focal adhesion assembly in Xenopus XR1 glial cells. Glia 26:245-259.
34. Takahashi, M., Takahashi, K., Hiratsuka, Y., Uchida, K., Yamagishi, A., Uyeda, T. Q., and Yazawa, M. 2001. Functional characterization of vertebrate nonmuscle myosin IIB isoforms using Dictyostelium chimeric myosin II. J. Biol. Chem. 276:1034-1040.
35. Maniak, M. 2001. Cell adhesion: Ushering in a new understanding of myosin VII. Curr. Biol. 11:R315-R317.