메뉴 건너뛰기




Volumn 138, Issue 11, 2002, Pages 1429-1432

Mechanisms of aging

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLATION; AGING; APOPTOSIS; CELL LOSS; CELL PROLIFERATION; DNA DAMAGE; GENETIC ANALYSIS; LONGEVITY; PHENOTYPE; PRIORITY JOURNAL; REVIEW; SENESCENCE; TELOMERE;

EID: 0036846217     PISSN: 0003987X     EISSN: None     Source Type: Journal    
DOI: 10.1001/archderm.138.11.1429     Document Type: Review
Times cited : (23)

References (59)
  • 1
    • 0030025660 scopus 로고    scopus 로고
    • Replicative senescence: An old lives' tale?
    • Campisi J. Replicative senescence: An old lives' tale? Cell. 1996;84:497-500.
    • (1996) Cell , vol.84 , pp. 497-500
    • Campisi, J.1
  • 2
    • 0037123654 scopus 로고    scopus 로고
    • Genomic priorities in aging
    • Hasty P, Vijg J. Genomic priorities in aging. Science. 2002;296:1250-1251.
    • (2002) Science , vol.296 , pp. 1250-1251
    • Hasty, P.1    Vijg, J.2
  • 3
    • 0036570012 scopus 로고    scopus 로고
    • Repair of oxidative DNA damage in nuclear and mitochondrial DNA, and some changes with aging in mammalian cells
    • Bohr V. Repair of oxidative DNA damage in nuclear and mitochondrial DNA, and some changes with aging in mammalian cells. Free Radic Biol Med. 2002;32: 804-812.
    • (2002) Free Radic Biol Med , vol.32 , pp. 804-812
    • Bohr, V.1
  • 4
    • 0011555560 scopus 로고
    • Correlation between deoxyribonucleic acid excision-repair and life-span in a number of mammalian species
    • Hart RW, Setlow RB. Correlation between deoxyribonucleic acid excision-repair and life-span in a number of mammalian species. Proc Natl Acad Sci U S A. 1974;71:2169-2173.
    • (1974) Proc Natl Acad Sci U S A , vol.71 , pp. 2169-2173
    • Hart, R.W.1    Setlow, R.B.2
  • 5
    • 0021780726 scopus 로고
    • Relationship between metabolic rate, free radicals, differentiation and aging: A unified theory
    • Woodhead AV, Blackett AD, Hollaender A, eds. New York, NY: Plenum Press
    • Sohal RS, Allen RG. Relationship between metabolic rate, free radicals, differentiation and aging: A unified theory. In: Woodhead AV, Blackett AD, Hollaender A, eds. The Molecular Biology of Aging. New York, NY: Plenum Press; 1985:75-104.
    • (1985) The Molecular Biology of Aging , pp. 75-104
    • Sohal, R.S.1    Allen, R.G.2
  • 6
    • 0344622606 scopus 로고
    • The serial cultivation of human diploid cell strains
    • Hayflick L, Moorehead PS. The serial cultivation of human diploid cell strains. Exp Cell Res. 1961;25:585-621.
    • (1961) Exp Cell Res , vol.25 , pp. 585-621
    • Hayflick, L.1    Moorehead, P.S.2
  • 7
    • 50549218525 scopus 로고
    • The limited in vitro lifetime of human diploid cell strains
    • Hayflick L. The limited in vitro lifetime of human diploid cell strains. Exp Cell Res. 1965;37:614-636.
    • (1965) Exp Cell Res , vol.37 , pp. 614-636
    • Hayflick, L.1
  • 8
    • 0001068487 scopus 로고
    • The relationship between in vitro cellular aging and in vivo human age
    • Schneider EL, Mitsui Y. The relationship between in vitro cellular aging and in vivo human age. Proc Natl Acad Sci U S A. 1976;73:3584-3588.
    • (1976) Proc Natl Acad Sci U S A , vol.73 , pp. 3584-3588
    • Schneider, E.L.1    Mitsui, Y.2
  • 9
    • 0014816132 scopus 로고
    • Replicative life-span of cultivated human cells: Effects of donor's age, tissue, and genotype
    • Martin GM, Sprague CA, Epstein CJ. Replicative life-span of cultivated human cells: Effects of donor's age, tissue, and genotype. Lab Invest. 1970;23:86-92.
    • (1970) Lab Invest , vol.23 , pp. 86-92
    • Martin, G.M.1    Sprague, C.A.2    Epstein, C.J.3
  • 10
    • 0022402513 scopus 로고
    • Identification of a specific telomere terminal transferase activity in Tetrahymena extracts
    • Greider CW, Blackburn EW. Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. Cell. 1985;43:405-413.
    • (1985) Cell , vol.43 , pp. 405-413
    • Greider, C.W.1    Blackburn, E.W.2
  • 12
    • 0026460896 scopus 로고
    • Telomere length predicts replicative capacity of human fibroblasts
    • Allsopp RC, Vaziri H, Patterson C, et al. Telomere length predicts replicative capacity of human fibroblasts. Proc Natl Acad Sci U S A. 1992;89:10114-10118.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 10114-10118
    • Allsopp, R.C.1    Vaziri, H.2    Patterson, C.3
  • 13
    • 0034875078 scopus 로고    scopus 로고
    • Telomeres and telomerase: Basic science implications for aging
    • Ahmed A, Tollefsbol T. Telomeres and telomerase: Basic science implications for aging. J Am Geriatr Soc. 2001;49:1105-1109.
    • (2001) J Am Geriatr Soc , vol.49 , pp. 1105-1109
    • Ahmed, A.1    Tollefsbol, T.2
  • 15
    • 0029686475 scopus 로고    scopus 로고
    • Telomerase and cancer
    • DeVita VT, Hellman S, Rosenberg SA, eds. Philadelphia, Pa: Lippincott-Raven
    • Harley CB, Kim NW. Telomerase and cancer. In: DeVita VT, Hellman S, Rosenberg SA, eds. Important Advances in Oncology. Philadelphia, Pa: Lippincott-Raven; 1996:57-67.
    • (1996) Important Advances in Oncology , pp. 57-67
    • Harley, C.B.1    Kim, N.W.2
  • 16
    • 0034597794 scopus 로고    scopus 로고
    • Telomere states and cell fates
    • Blackburn E. Telomere states and cell fates. Nature. 2000;408:53-56.
    • (2000) Nature , vol.408 , pp. 53-56
    • Blackburn, E.1
  • 17
    • 0032489012 scopus 로고    scopus 로고
    • TRF2 protects telomeres from end-to-end fusions
    • van Steensel B, Smogorewska A, de Lange T. TRF2 protects telomeres from end-to-end fusions. Cell. 1998;92:401-413.
    • (1998) Cell , vol.92 , pp. 401-413
    • Van Steensel, B.1    Smogorewska, A.2    De Lange, T.3
  • 18
    • 0033605145 scopus 로고    scopus 로고
    • p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2
    • Karlseder J, Broccoli D, Dai Y, Hardy S, de Lange T. p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2. Science. 1999;283:1321-1325.
    • (1999) Science , vol.283 , pp. 1321-1325
    • Karlseder, J.1    Broccoli, D.2    Dai, Y.3    Hardy, S.4    De Lange, T.5
  • 20
    • 0035185159 scopus 로고    scopus 로고
    • Stimulation of melanogenesis by DNA oligonucleotides: Effect of size, sequence and 5′ phosphorylation
    • Hadshiew IM, Eller MS, Gasparro FP, Gilchrest BA. Stimulation of melanogenesis by DNA oligonucleotides: Effect of size, sequence and 5′ phosphorylation. J Dermatol Sci. 2001;25:127-138.
    • (2001) J Dermatol Sci , vol.25 , pp. 127-138
    • Hadshiew, I.M.1    Eller, M.S.2    Gasparro, F.P.3    Gilchrest, B.A.4
  • 21
    • 0030785521 scopus 로고    scopus 로고
    • Enhancement of DNA repair in human skin cells by thymidine dinucleotides: Evidence for a p53-mediated mammalian SOS response
    • Eller MS, Maeda T, Magnoni C, Atwal D, Gilchrest BA. Enhancement of DNA repair in human skin cells by thymidine dinucleotides: Evidence for a p53-mediated mammalian SOS response. Proc Natl Acad Sci U S A. 1997;94:12627-12632.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 12627-12632
    • Eller, M.S.1    Maeda, T.2    Magnoni, C.3    Atwal, D.4    Gilchrest, B.A.5
  • 22
    • 0011350021 scopus 로고    scopus 로고
    • Induction of replicative senescence markers by telomere 3′ overhang specific DNA
    • Li GZ, Eller MS, Gilchrest BA. Induction of replicative senescence markers by telomere 3′ overhang specific DNA [abstract]. J Invest Dermatol. 2001;117: 792.
    • (2001) J Invest Dermatol , vol.117 , pp. 792
    • Li, G.Z.1    Eller, M.S.2    Gilchrest, B.A.3
  • 23
    • 0011311657 scopus 로고    scopus 로고
    • Evidence that senescence is due to exposure of telomere 3′ overhang specific DNA following critical telomere shortening
    • In press
    • Li GZ, Eller MS, Gilchrest BA. Evidence that senescence is due to exposure of telomere 3′ overhang specific DNA following critical telomere shortening [abstract]. J Invest Dermatol. In press.
    • J Invest Dermatol
    • Li, G.Z.1    Eller, M.S.2    Gilchrest, B.A.3
  • 24
    • 0013903520 scopus 로고
    • Pyrimidine dimers in ultraviolet-irradiated DNAs
    • Setlow RB, Carrier WL. Pyrimidine dimers in ultraviolet-irradiated DNAs. J Mol Biol. 1966;17:237-254.
    • (1966) J Mol Biol , vol.17 , pp. 237-254
    • Setlow, R.B.1    Carrier, W.L.2
  • 25
    • 0002738322 scopus 로고
    • Formation of 8-hydroxydeoxyguanosine in DNA by oxygen radicals and its biological significance
    • Sies H, ed. London, England: Academic Press, Ltd
    • Kasai H, Nishimura S. Formation of 8-hydroxydeoxyguanosine in DNA by oxygen radicals and its biological significance. In: Sies H, ed. Oxidative Stress: Oxidants and Antioxidants. London, England: Academic Press, Ltd; 1991:99-116.
    • (1991) Oxidative Stress: Oxidants and Antioxidants , pp. 99-116
    • Kasai, H.1    Nishimura, S.2
  • 26
    • 0034327409 scopus 로고    scopus 로고
    • Formation of cisdiamminedichloroplatinum(II) 1,2-intrastrand cross-links on DNA is flanking-sequence independent
    • Burstyn JN, Heiger-Bernays WJ, Cohen SM, Lippard SJ. Formation of cisdiamminedichloroplatinum(II) 1,2-intrastrand cross-links on DNA is flanking-sequence independent. Nucleic Acids Res. 2000;28:4237-4243.
    • (2000) Nucleic Acids Res , vol.28 , pp. 4237-4243
    • Burstyn, J.N.1    Heiger-Bernays, W.J.2    Cohen, S.M.3    Lippard, S.J.4
  • 27
    • 0032772792 scopus 로고    scopus 로고
    • Site-specific DNA damage at GGG sequence by oxidative stress may accelerate telomere shortening
    • Oikawa S, Kawanishi S. Site-specific DNA damage at GGG sequence by oxidative stress may accelerate telomere shortening. FEBS Lett. 1999;453:365-368.
    • (1999) FEBS Lett , vol.453 , pp. 365-368
    • Oikawa, S.1    Kawanishi, S.2
  • 28
    • 0032515974 scopus 로고    scopus 로고
    • Telomere loss in cells treated with cisplatin
    • Ishibashi T, Lippard SJ. Telomere loss in cells treated with cisplatin. Proc Natl Acad Sci U S A. 1998;95:4219-4223.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 4219-4223
    • Ishibashi, T.1    Lippard, S.J.2
  • 30
    • 0028915068 scopus 로고
    • Different regulation of p53 stability in UV-irradiated normal and DNA repair deficient human cells
    • Abrahams PJ, Schouten R, van Laar T, Houweling A, Terleth C, van der Eb AJ. Different regulation of p53 stability in UV-irradiated normal and DNA repair deficient human cells. Mutat Res. 1995;336:169-180.
    • (1995) Mutat Res , vol.336 , pp. 169-180
    • Abrahams, P.J.1    Schouten, R.2    Van Laar, T.3    Houweling, A.4    Terleth, C.5    Van der Eb, A.J.6
  • 31
    • 0030671254 scopus 로고    scopus 로고
    • Abnormal telomere dynamics of B-lymphoblastoid cell strains from Werner's syndrome patients transformed by Epstein-Barr virus
    • Tahara H, Tokutake Y, Maeda S, et al. Abnormal telomere dynamics of B-lymphoblastoid cell strains from Werner's syndrome patients transformed by Epstein-Barr virus. Oncogene. 1997;15:1911-1920.
    • (1997) Oncogene , vol.15 , pp. 1911-1920
    • Tahara, H.1    Tokutake, Y.2    Maeda, S.3
  • 33
    • 0035109348 scopus 로고    scopus 로고
    • Mechanism of guanine-specific DNA damage by oxidative stress and its role in carcinogenesis and aging
    • Kawanishi S, Hiraku Y, Oikawa S. Mechanism of guanine-specific DNA damage by oxidative stress and its role in carcinogenesis and aging. Mutat Res. 2001;488:65-76.
    • (2001) Mutat Res , vol.488 , pp. 65-76
    • Kawanishi, S.1    Hiraku, Y.2    Oikawa, S.3
  • 34
    • 0032485213 scopus 로고    scopus 로고
    • Agents that cause DNA double strand breaks lead to p16INK4a enrichment and the premature senescence of normal fibroblasts
    • Robles SJ, Adami GR. Agents that cause DNA double strand breaks lead to p16INK4a enrichment and the premature senescence of normal fibroblasts. Oncogene. 1998;16:1113-1123.
    • (1998) Oncogene , vol.16 , pp. 1113-1123
    • Robles, S.J.1    Adami, G.R.2
  • 35
    • 0030944985 scopus 로고    scopus 로고
    • Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
    • Serrano M, Lin AW, McCurrach ME, Beach D, Lowe SW. Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell. 1997;88:593-602.
    • (1997) Cell , vol.88 , pp. 593-602
    • Serrano, M.1    Lin, A.W.2    McCurrach, M.E.3    Beach, D.4    Lowe, S.W.5
  • 36
    • 0034028836 scopus 로고    scopus 로고
    • Tumor suppressors and oncogenes in cellular senescence
    • Bringold F, Serrano M. Tumor suppressors and oncogenes in cellular senescence. Exp Gerontol. 2000;35:317-329.
    • (2000) Exp Gerontol , vol.35 , pp. 317-329
    • Bringold, F.1    Serrano, M.2
  • 37
    • 0032192153 scopus 로고    scopus 로고
    • Senescence of human fibroblasts induced by oncogenic raf
    • Zhu J, Woods D, McMahon M, Bishop JM. Senescence of human fibroblasts induced by oncogenic raf. Genes Dev. 1998;12:2997-3007.
    • (1998) Genes Dev , vol.12 , pp. 2997-3007
    • Zhu, J.1    Woods, D.2    McMahon, M.3    Bishop, J.M.4
  • 38
    • 0032190629 scopus 로고    scopus 로고
    • Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling
    • Lin AW, Barradas M, Stone JC, van Aelst L, Serrano M, Lowe SW. Premature senescence involving p53 and p16 is activated in response to constitutive MEK/ MAPK mitogenic signaling. Genes Dev. 1998;12:3008-3019.
    • (1998) Genes Dev , vol.12 , pp. 3008-3019
    • Lin, A.W.1    Barradas, M.2    Stone, J.C.3    Van Aelst, L.4    Serrano, M.5    Lowe, S.W.6
  • 39
    • 0033989829 scopus 로고    scopus 로고
    • Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14/ARF tumor suppressor
    • Dimri GP, Itahana K, Acosta M, Campisi J. Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14/ARF tumor suppressor. Mol Cell Biol. 2000;20:273-285.
    • (2000) Mol Cell Biol , vol.20 , pp. 273-285
    • Dimri, G.P.1    Itahana, K.2    Acosta, M.3    Campisi, J.4
  • 40
    • 0032510327 scopus 로고    scopus 로고
    • Inhibitors of cyclin-dependent kinases induce features of replicative senescence in early passage human diploid fibroblasts
    • McConnell BB, Starborg M, Brookes S, Peters G. Inhibitors of cyclin-dependent kinases induce features of replicative senescence in early passage human diploid fibroblasts. Curr Biol. 1998;8:351-354.
    • (1998) Curr Biol , vol.8 , pp. 351-354
    • McConnell, B.B.1    Starborg, M.2    Brookes, S.3    Peters, G.4
  • 41
    • 0028998866 scopus 로고
    • Mutations associated with familial melanoma impair p16INK4 function
    • Ranade K, Hussussian CJ, Sikorski RS, et al. Mutations associated with familial melanoma impair p16INK4 function. Nat Genet. 1995;10:114-116.
    • (1995) Nat Genet , vol.10 , pp. 114-116
    • Ranade, K.1    Hussussian, C.J.2    Sikorski, R.S.3
  • 42
    • 0034832956 scopus 로고    scopus 로고
    • Regulation of cellular senescence by p53
    • Itahana K, Dimri G, Campisi J. Regulation of cellular senescence by p53. Eur J Biochem. 2001;268:2784-2791.
    • (2001) Eur J Biochem , vol.268 , pp. 2784-2791
    • Itahana, K.1    Dimri, G.2    Campisi, J.3
  • 43
    • 0029778901 scopus 로고    scopus 로고
    • Human fibroblast commitment to a senescence-like state in response to histone deacetylase inhibitors is cell cycle dependent
    • Ogryzko W, Hirai TH, Russanova VR, Barbie DA, Howard BH. Human fibroblast commitment to a senescence-like state in response to histone deacetylase inhibitors is cell cycle dependent. Mol Cell Biol. 1996;16:5210-5218.
    • (1996) Mol Cell Biol , vol.16 , pp. 5210-5218
    • Ogryzko, W.1    Hirai, T.H.2    Russanova, V.R.3    Barbie, D.A.4    Howard, B.H.5
  • 44
    • 0035876388 scopus 로고    scopus 로고
    • Histone deacetylases in replicative senescence: Evidence for a senescence-specific form of HDAC-2
    • Wagner M, Brosch G, Zwerschke W, Seto E, Loidl P, Jansen-Durr P. Histone deacetylases in replicative senescence: Evidence for a senescence-specific form of HDAC-2. FEBS Lett. 2001;499:101-106.
    • (2001) FEBS Lett , vol.499 , pp. 101-106
    • Wagner, M.1    Brosch, G.2    Zwerschke, W.3    Seto, E.4    Loidl, P.5    Jansen-Durr, P.6
  • 45
    • 0029047362 scopus 로고
    • A biomarker that identifies senescent human cells in culture and in aging skin in vivo
    • Dimri GP, Lee X, Basile G, et al. A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc Natl Acad Sci U S A. 1995;92:9363-9367.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 9363-9367
    • Dimri, G.P.1    Lee, X.2    Basile, G.3
  • 46
    • 0026588862 scopus 로고
    • Common senescent cell-specific antibody epitopes on fibronectin in species and cells of varied origin
    • Porter MB, Pereira-Smith OM, Smith JR. Common senescent cell-specific antibody epitopes on fibronectin in species and cells of varied origin. J Cell Physiol. 1992;150:545-551.
    • (1992) J Cell Physiol , vol.150 , pp. 545-551
    • Porter, M.B.1    Pereira-Smith, O.M.2    Smith, J.R.3
  • 47
    • 0030042853 scopus 로고    scopus 로고
    • Differential regulation of collagenase and stromelysin mRNA in late passage cultures of human fibroblasts
    • Zeng G, Millis AJ. Differential regulation of collagenase and stromelysin mRNA in late passage cultures of human fibroblasts. Exp Cell Res. 1996;222:150-156.
    • (1996) Exp Cell Res , vol.222 , pp. 150-156
    • Zeng, G.1    Millis, A.J.2
  • 48
    • 0033034497 scopus 로고    scopus 로고
    • Aging differentially modulates the expression of collagen and collagenase in dermal fibroblasts
    • Khorramizadeh MR, Tredget EE, Telasky C, Shen Q, Ghahary A. Aging differentially modulates the expression of collagen and collagenase in dermal fibroblasts. Mol Cell Biochem. 1999;194:99-108.
    • (1999) Mol Cell Biochem , vol.194 , pp. 99-108
    • Khorramizadeh, M.R.1    Tredget, E.E.2    Telasky, C.3    Shen, Q.4    Ghahary, A.5
  • 49
    • 0028323425 scopus 로고
    • Altered transcriptional regulation of human interstitial collagenase in cultured skin fibroblasts from older donors
    • Burke EM, Horton WE, Pearson JD, Crow MT, Martin GR. Altered transcriptional regulation of human interstitial collagenase in cultured skin fibroblasts from older donors. Exp Gerontol. 1994;29:37-53.
    • (1994) Exp Gerontol , vol.29 , pp. 37-53
    • Burke, E.M.1    Horton, W.E.2    Pearson, J.D.3    Crow, M.T.4    Martin, G.R.5
  • 50
    • 0025158110 scopus 로고
    • A presumed DNA helicase encoded by ERCC-3 is involved in the human repair disorders xeroderma pigmentosum and Cockayne's syndrome
    • Weeda G, van Ham RC, Vermeulen W, Bootsma D, van der Eb AJ, Hoeijmakers JH. A presumed DNA helicase encoded by ERCC-3 is involved in the human repair disorders xeroderma pigmentosum and Cockayne's syndrome. Cell. 1990;62:777-791.
    • (1990) Cell , vol.62 , pp. 777-791
    • Weeda, G.1    Van Ham, R.C.2    Vermeulen, W.3    Bootsma, D.4    Van der Eb, A.J.5    Hoeijmakers, J.H.6
  • 51
    • 0026465665 scopus 로고
    • ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genes
    • Troelstra C, van Gool A, de Wit J, Vermeulen W, Bootsma D, Hoeijmakers JH. ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genes. Cell. 1992;71:939-953.
    • (1992) Cell , vol.71 , pp. 939-953
    • Troelstra, C.1    Van Gool, A.2    De Wit, J.3    Vermeulen, W.4    Bootsma, D.5    Hoeijmakers, J.H.6
  • 52
    • 0029057336 scopus 로고
    • A single ataxia telangiectasia gene with a product similar to PI-3 kinase
    • Savitsky K, Bar-Shira A, Gilad S, et al. A single ataxia telangiectasia gene with a product similar to PI-3 kinase. Science. 1995;268:1749-1753.
    • (1995) Science , vol.268 , pp. 1749-1753
    • Savitsky, K.1    Bar-Shira, A.2    Gilad, S.3
  • 53
    • 15844409553 scopus 로고    scopus 로고
    • Positional cloning of the Werner's syndrome gene
    • Yu CE, Oshima J, Fu YH, et al. Positional cloning of the Werner's syndrome gene. Science. 1996;272:258-262.
    • (1996) Science , vol.272 , pp. 258-262
    • Yu, C.E.1    Oshima, J.2    Fu, Y.H.3
  • 55
    • 0023354422 scopus 로고
    • Aging can be genetically dissected into component processes using long-lived lines of Caenorhabditis elegans
    • Johnson TE. Aging can be genetically dissected into component processes using long-lived lines of Caenorhabditis elegans. Proc Natl Acad Sci U S A. 1987;84:3777-3781.
    • (1987) Proc Natl Acad Sci U S A , vol.84 , pp. 3777-3781
    • Johnson, T.E.1
  • 56
    • 0029087068 scopus 로고
    • A coordinate upregulation of antioxidant gene activities is associated with the delayed onset of senescence in a long-lived strain of Drosophila
    • Dudas SP, Arking R. A coordinate upregulation of antioxidant gene activities is associated with the delayed onset of senescence in a long-lived strain of Drosophila. J Gerontol A Biol Sci Med Sci. 1995;50:B117-B127.
    • (1995) J Gerontol A Biol Sci Med Sci , vol.50
    • Dudas, S.P.1    Arking, R.2
  • 57
    • 0030016821 scopus 로고    scopus 로고
    • Longevity, genes and aging
    • Jazwinski SM. Longevity, genes and aging. Science. 1996;273:54-59.
    • (1996) Science , vol.273 , pp. 54-59
    • Jazwinski, S.M.1
  • 58
    • 0024571702 scopus 로고
    • Inheritance of immune responsiveness, life span, and disease incidence in interline crosses of mice selected for high or low multispecific antibody production
    • Covelli V, Mouton D, Di Maio V, et al. Inheritance of immune responsiveness, life span, and disease incidence in interline crosses of mice selected for high or low multispecific antibody production. J Immunol. 1989;142:1224-1234.
    • (1989) J Immunol , vol.142 , pp. 1224-1234
    • Covelli, V.1    Mouton, D.2    Di Maio, V.3
  • 59
    • 0037123638 scopus 로고    scopus 로고
    • Premature aging in mice deficient in DNA repair and transcription
    • de Boer J, Andressoo JO, de Wit J, et al. Premature aging in mice deficient in DNA repair and transcription. Science. 2002;296:1276-1279.
    • (2002) Science , vol.296 , pp. 1276-1279
    • De Boer, J.1    Andressoo, J.O.2    De Wit, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.