Mutation of ARX causes abnormal development of forebrain and testes in mice and X-linked lissencephaly with abnormal genitalia in humans

Nature Genetics

Volumn 32, Issue 3, 2002, Pages 359-369

  Kitamura, Kunio ^a   Yanazawa, Masako ^a   Sugiyama, Noriyuki ^b,c   Miura, Hirohito ^a   Iizuka Kogo, Akiko ^b   Kusaka, Masatomo ^b,c   Omichi, Kayo ^a   Suzuki, Rika ^a   Kato Fukui, Yuko ^a   Kamiirisa, Kyoko ^a   Matsuo, Mina ^a   Kamijo, Shin Ichi ^a   Kasahara, Megumi ^d   Yoshioka, Hidefumi ^c,d   Ogata, Tsutomu ^e   Fukuda, Takayuki ^f,g   Kondo, Ikuko ^f   Kato, Mitsuhiro ^h   Dobyns, William B ^h   Yokoyama, Minesuke ^a   Morohashi, Ken Ichirou ^b,c   more..

^a MITSUBISHI KAGAKU INSTITUTE OF LIFE SCIENCES   (Japan)

^b NATIONAL INSTITUTE FOR BASIC BIOLOGY   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^d HYOGO UNIVERSITY OF TEACHER EDUCATION   (Japan)

^e KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^f EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^g EHIME UNIVERSITY   (Japan)

^h UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; HOMEODOMAIN PROTEIN; PROTEIN ARX; UNCLASSIFIED DRUG;

AGYRIA; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN MALFORMATION; CELL DIFFERENTIATION; CELL MIGRATION; CELL PROLIFERATION; CLINICAL FEATURE; CONTROLLED STUDY; DEVELOPMENTAL DISORDER; DISEASE ASSOCIATION; DISEASE COURSE; FEMALE; GENE EXPRESSION; GENE IDENTIFICATION; GENE LOCATION; GENE MUTATION; GENITAL MALFORMATION; HUMAN; MOUSE; NERVE CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; TESTIS; X LINKED LISSENCEPHALY WITH ABNORMAL GENITALIA;

ALLELES; AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; BASE SEQUENCE; BRAIN; BROMODEOXYURIDINE; CELL DIFFERENTIATION; CELL DIVISION; CELL MOVEMENT; DNA, COMPLEMENTARY; EPITHELIAL CELLS; GENETIC VECTORS; GENITALIA; HOMEODOMAIN PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; LINKAGE (GENETICS); MALE; MICE; MICE, KNOCKOUT; MICROSCOPY, FLUORESCENCE; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; MUTATION; NEURONS; PHENOTYPE; PROSENCEPHALON; SYNDROME; TESTIS; TRANSCRIPTION FACTORS; TRANSFECTION; X CHROMOSOME;

ANIMALIA;

EID: 0036844387     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/ng1009     Document Type: Article

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