Adrenocortical and gonadal expression of the mammalian Ftz-F1 gene encoding Ad4BP/SF-1 is independent of pituitary control

Journal of Biochemistry

Volumn 124, Issue 1, 1998, Pages 217-224

  Nomura, Masatoshi ^a,d   Kawabe, Ken ^a,d,e   Matsushita, Sumie ^a   Oka, Sanae ^e   Hatano, Osamu ^b   Harada, Nobuhiro ^c   Nawata, Hajime ^d   Morohashi, Ken Ichirou ^a,e  

^a KYUSHU UNIVERSITY   (Japan)

^b NARA MEDICAL UNIVERSITY   (Japan)

^c FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d KYUSHU UNIVERSITY   (Japan)

^e NATIONAL INSTITUTE FOR BASIC BIOLOGY   (Japan)

Author keywords

Ad4BP SF 1; Adrenal cortex; Ftz F1; Gonad; Nuclear receptor

Indexed keywords

CYCLIC AMP; CYTOCHROME P450; PEPTIDE HORMONE; TRANSCRIPTION FACTOR;

ADRENAL CORTEX CELL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; GENE CONTROL; GENE EXPRESSION; GONAD; HYPOPHYSECTOMY; HYPOPHYSIS; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; HYPOTHALAMUS HYPOPHYSIS GONAD SYSTEM; IMMUNOCHEMISTRY; LEYDIG CELL; MALE; MOUSE; NONHUMAN; OVARY; RAT; TESTIS;

ANIMALIA; MAMMALIA;

EID: 0031848179     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a022083     Document Type: Article

References (56)

1. Morohashi, K. and Omura, T. (1996) Ad4BP/SF-1, a transcription factor essential for the transcription of steroidogenic cytochrome P450 genes and for the establishment of the reproductive function. FASEB J. 10, 1569-1577
2. Honda, S., Morohashi, K., and Omura, T. (1990) Novel cAMP regulatory elements in the promoter region of bovine P-450(11β) gene. J. Biochem. 108, 1042-1049
3. Rice, D.A., Kirkman, M.S., Aitken, L.D., Mouw, A.R., Schimmer, B.P., and Parker, K.L. (1990) Analysis of the promoter region of the gene encoding mouse cholesterol side-chain cleavage enzyme. J. Biol. Chem. 265, 11713-11720
4. Morohashi, K., Zanger, U.M., Honda, S., Hara, M., Waterman, M.R., and Omura, T. (1993) Activation of CYP11A and CYP11B gene promoters by the steroidogenic cell-specific transcription factor, Ad4BP. Mol. Endocrinol. 7, 1196-1204
5. Morohashi, K. and Omura, T. (1996) Gene regulation of steroidogenesis. J. Steroid Biochem. Mol. Biol. 53, 19-25
6. Parker, K.L. and Schimmer, B.P. (1993) Transcriptional regulation of the adrenal steroidogenic enzymes. Trends Endocrinol. Metab. 4, 46-50
7. Waterman, M.R. (1994) Biochemical diversity of cAMP-dependent transcription of steroid hydroxylase genes in the adrenal cortex. J. Biol. Chem. 269, 27783-27786
8. Morohashi, K., Iida, H., Nomura, M., Hatano, O., Honda, S., Tsukiyama, T., Niwa, O., Hara, T., Takakusu, A., Shibata, Y., and Omura, T. (1994) Functional difference between Ad4BP and ELP, and their distributions in the steroidogenic tissues. Mol. Endocrinol. 8, 643-653
9. Ikeda, Y., Lala, D.S., Luo, X., Kim, E., Moison, M-P., and Parker, K.L. (1993) Characterization of the mouse FTZ-F1 gene, which encodes a key regulator of steroid hydroxylase gene expression. Mol. Endocrinol. 7, 852-860
10. Ingraham, H.I., Lala, D.S., Ikeda, Y., Luo, X., Shen, W-H., Nachtingal, M.W., Abbud, R., Nilson, J.H., and Parker, K.L. (1994) The nuclear receptor steroidogenic factor 1 acts at multiple levels of the reproductive axis. Genes Dev. 8, 2302-2312
11. Shinoda, K., Lei, H., Yoshii, H., Nomura, M., Nagano, M., Shiba, H., Sasaki, H., Osawa, Y., Ninomiya, Y., Niwa, O., Morohashi, K., and Li, E. (1995) Developmental defects of the ventromedial hypothalamic nucleus and pituitary gonadotroph in the ftz-F1 disrupted mice. Dev. Dynam. 204, 22-29
12. Barnhart, K.M. and Mellon, P.L. (1995) The orphan nuclear receptor, steroidogenic factor-1, regulates the glycoprotein hormone α-subunit gene in pituitary gonadotropes. Mol. Endocrinol. 8, 878-885
13. Halvorson, L.M., Kaiser, U.B., and Chin, W.W. (1996) Stimulation of luteinizing hormones β gene promoter activity by the orphan nuclear receptor, steroidogenic factor-1. J. Biol. Chem. 271, 6645-6650
14. Drean, Y.L., Liu, D., Wong, A.O.L., Xiong, F., and Hew, C.L. (1996) Steroidogenic factor 1 and estradiol receptor act synergism to regulate the expression of the salmon gonadotropin II/β subunit gene. Mol. Endocrinol. 10, 217-229
15. Lee, S.L., Sadovsky, Y., Swirnoff, A.H., Polish, J.A., Goda, P., Gavrilina, G., and Milbrandt, J. (1996) Luteinizing hormone deficiency and female infertility in mice lacking the transcription factor NGFI-A (Egr-1). Science 273, 1219-1221
16. Halasz, B. (1994) Hypothalamo-anterior pituitary system and pituitary portal vessels in The Pituitary Gland (Imura, H., ed.) pp. 1-28, Raven Press, New York
17. Quinn, S.J. and Williams, G.H. (1992) Regulation of aldosterone secretion in The Adrenal Gland (James, V.H.T., ed.) pp. 159-189, Raven Press, New York
18. Dissen, G.A., Dees, W.L., and Ojeda, S.R. (1993) Neural and neurotrophic control of ovarian development in The Ovary (Adashi, E.Y. and Leung, P.C.K., eds.) pp. 1-19, Raven Press, New York
19. Dorrington, J.H. and Khan, S.A. (1993) Steroid production, metabolism, and release by Sertoli cells in The Sertoli Cell (Russell, L.D. and Griswold, M.D., eds.) pp. 537-549, Cache River Press, Clearwater, FL
20. Luo, X., Ikeda, Y., and Parker, K.L. (1994) A cell-specific nuclear receptor is essential for adrenal and gonadal development and sexual differentiation. Cell 77, 481-490
21. Sadovsky, Y., Crawford, P.A., Woodson, K.G., Polish, J.A., Clements, M.A., Tourtellotte, L.A., Simburger, K., and Milbrandt, J. (1995) Mice deficient in the orphan receptor steroidogenic factor 1 lack adrenal glands and gonads but express P450 sidechain-cleavage enzyme in the placenta and have normal embryonic serum levels of corticosteroids. Proc Natl. Acad. Sci. USA 92, 10939-10943
22. Hatano, O., Takakusu, A., Nomura, M., and Morohashi, K. (1996) Identical origin of adrenal cortex and gonad revealed by expression profiles of Ad4BP/SF-1. Genes Cells 1, 663-671
23. Morohashi, K. (1997) The ontogenesis of the steroidogenic tissues. Genes Cells 2, 95 106
24. Takayama, K., Sasano, H., Fukaya, T., Morohashi, K., Suzuki, T., Tamura, M., Costa, M.J., and Yajima, A. (1995) Immunohistochemical localization of Ad4-binding protein with correlation to steroidogenic enzyme expression in cycling human ovaries and sex cord stromal tumors. J. Clin. Endocrinol. Metab. 80, 2815-2821
25. Hatano, O., Takayama, K., Imai, T., Waterman, M.R., Takakusu, A., Omura, T., and Morohashi, K. (1994) Sex-dependent expression of a transcription factor, Ad4BP, regulating steroidogenic P-450 genes in the gonads during prenatal and postnatal rat development. Development 120, 2787-2797
26. Kirita, S., Hashimoto, T., Kitajima, M., Honda, S., Morohashi, K., and Omura, T. (1990) Structural analysis of multiple bovine P-450(11β) genes and their promoter activities. J. Biochem. 108, 1030-1041
27. Nomura, M., Nawata, H., and Morohashi, K. (1996) Autoregulatory loop in the regulation of the mammalian ftz-f1 gene. J. Biol. Chem. 271, 8243-8249
28. Takayama, T., Morohashi, K., Honda, S., Hara, N., and Omura, T. (1994) Contribution of Ad4BP, a steroidogenic cell-specific transcription factor, to the regulation of the human CYP11A and bovine CYP11B genes through their distal promoters. J. Biochem. 116, 193-203
29. Bakke, M. and Lund, J. (1995) Mutually exclusive interactions of two nuclear orphan receptors determine activity of a cyclic adenosine 3′,5′-monophosphate-responsive sequence in the bovine CYP17 gene. Mol. Endocrinol. 9, 327-339
30. Zhang, P. and Mellon, S.H. (1996) The orphan nuclear receptor steroidogenic factor-1 regulates the cyclic adenosine 3′,5′-monophosphate-mediated transcriptional activation of rat cytochrome P450cl7 (17α-hydroxylase/c17-201yase). Mol. Endocrinol. 10, 147-158
31. Chen, C-T., Guo, I-C., and Chung, B-C. (1995) Regulation of cholesterol side-chain cleavage cytochrome P450 in mouse testis Leydig cell line I-10. DNA Cell. Biol. 14, 803-810
32. Colby, H.D., Malendowicz, L.K., Caffrey, J.L., and Kitay, J.I. (1974) Effects of hypophysectomy and ACTH on adrenocortical function in the rat. Endocrinology 94, 1346-1350
33. Stocco, D.M., Teerds, K.J., von Noort, M., and Rommerts, F.F.G. (1990) Effects of hypophysectomy and human chorionic gonadotropin on Leydig cell function in mature rats. J. Endocrinol. 126, 367-375
34. Imai, T., Seo, H., Murata, Y., Ohno, M., Satoh, Y., Funahashi, H., Takagi, H., and Matsui, N. (1990) Alteration in the expression of genes for cholesterol side-chain cleavage enzyme and 21-hydroxylase by hypophysectomy and ACTH administration in the rat adrenal. J. Mol. Endocrinol. 4, 239-245
35. Moore, C.C.D., Brentano, S.T., and Miller, W.L. (1990) Human P450scc gene transcription is induced by cyclic AMP and repressed by 12-O-tetradecanoylphorbol-13-acetate and A23187 through independent cis element. Mol. Cell. Biol. 10, 6013-6023
36. Rice, D.A., Kirkman, M.S., Aitken, L.D., Mouw, A.R., Schimmer, B.P., and Parker, K.L. (1990) Analysis of the promoter region of the gene encoding mouse cholesterol side-chain cleavage enzyme. J. Biol. Chem. 265, 11713-11720
37. Kawamoto, T., Mitsuuchi, Y., Toda, M., Miyahara, K., Yokoyama, Y., Nakao, K., Hosada, K., Yamamoto, Y., Imura, H., and Shizuta, Y. (1990) Cloning of cDNA and genomic DNA for human cytochrome P-45011β. FEBS Lett. 269, 345-349
38. Brentano, S.T., Picado-Leonard, J., Mellon, S.H., Moore, C.C.D., and Miller, W.L. (1990) Tissue-specific, cyclic adenosine 3′,5′-monophosphate-induced, and phorbol ester-repressed transcription from the human P450c17 promoter in mouse cells. Mol. Endocrinol. 4, 1972-1979
39. Mukai, K., Imai, M., Shimada, H., and Ishimura, Y. (1993) Isolation and characterization of rat CYP11B genes involved in late steps of mineralo- and glucocorticoid syntheses. J. Biol. Chem. 268, 9130-9337
40. Inoue, H., Watanabe, N., Higashi, Y., and Fujii-Kuriyama, Y. (1991) Structures of regulatory regions in the human cytochrome P-450scc (desmolase) gene. Eur. J. Biochem. 195, 563-569
41. Lauber, M.E., Bengtson, T., Waterman, M.R., and Simpson, E.R. (1991) Regulation of CYP11 (P450scc) and CYP17 (P45017α) gene expression in bovine luteal cells in primary culture. J. Biol. Chem. 266, 11170-11175
42. Momoi, K., Waterman, M.R., Simpson, E.R., and Zanger, U.M. (1992) 3′,5′-Cyclic adenosine monophosphate-dependent transcription of the CYP11A (cholesterol side chain cleavage cytochrome P450) gene involves a DNA response element containing a putative binding site for transcription factor Sp1. Mol. Endocrinol. 6, 1682-1690
43. Guo, I.C., Tsai, H.M., and Chung, B.C. (1994) Actions of two different cAMP-responsive sequences and an enhancer of the human CYP11A1 (P450scc) gene in adrenal Y1 and placental JEG-3 cells. J. Biol. Chem. 269, 6362-6369
44. Morohashi, K., Honda, S., Inamata, Y., Handa, H., and Omura, T. (1992) A common trans-acting factor, Ad4-binding protein, to the promoters of steroidogenic P-450s. J. Biol. Chem. 267, 17913-17919
45. Parker, K.L. and Schimmer, B.P. (1993) Transcriptional regulation of the adrenal steroidogenic enzymes. Trends Endocrinol. Metab. 4, 46-50
46. Crawford, P.A., Sadovsky, Y., Woodson, K., Lee, S.L., and Milbrandt, J. (1995) Adrenocortical function and regulation of the steroid 21-hydroxylase gene in NGFI-B-deficient mice. Mol. Cell. Biol. 15, 4331-4336
47. Haisenleder, D.J., Yasin, M., Dalkin, A.C., Gilrain, J., and Marshall, J.C. (1996) GnRH regulates steroidogenic factor-1 (SF-1) gene expression in the rat pituitary. Endocrinology 137, 5719-5722
48. Hughes, J.F.M. and Gorospe, W.C. (1991) Biochemical identification of apoptosis (programmed cell death) in granulosa cells: evidence for a potential mechanism underlying follicular atresia. Endocrinology 129, 2415-2422
49. Tilly, J.L., Kowalski, K.I., Johnson, A.L., and Hsueh, A.J.W. (1991) Involvement of apoptosis in ovarian follicular atresia and postovulatory regression. Endocrinology 129, 2799-2801
50. Palumbo, A.M. and Yeh, J. (1994) In situ localization of apoptosis in the rat ovary during follicular atresia. Biol. Repro. 51, 888-895
51. Habener, J.F. (1990) Cyclic AMP response element binding protein: a cornucopia of transcription factors. Mol. Endocrinol. 4, 1087-1094
52. Mangelsdorf, D.J., Thummel, C., Beato, M., Herrlich, P., Schutz, G., Umesono, K., Blumberg, B., Kastner, P., Mark, M., Chambon, P., and Evans, R.M. (1995) The nuclear receptor superfamily: The second decade. Cell 83, 835-839
53. Fujii-Kuriyama, Y., Imataka, H., Sogawa, K., Yasumoto, K., and Kikuchi, Y. (1992) Regulation of CYP1A1 expression. FASEB J. 6, 706-710
54. Verma, I.M., Stevenson, J.K., Schwarz, E.M., Antwerp, D.V., and Miyamoto, S. (1995) Rel/NF-kB/IkB family: intimate tales of association and dissociation. Genes Dev. 9, 2723-2735
55. Honda, S., Morohashi, K., Nomura, M., Takeya, H., Kitajima, M., and Omura, T. (1993) Ad4BP regulating steroidogenic P-450 gene is a member of steroid hormone receptor superfamily. J. Biol. Chem. 268, 7494-7502
56. Lala, D.S., Syka, P.M., Lazarchik, S.B., Mangelsdorf, D.J., Parker, K.L., and Heyman, R.A. (1997) Activation of the orphan nuclear receptor steroidogenic factor 1 by oxysterols. Proc. Natl. Acad. Sci. USA 94, 4895-4900