Expression of a novel aristaless related homeobox gene 'Arx' in the vertebrate telencephalon, diencephalon and floor plate

Mechanisms of Development

Volumn 65, Issue 1-2, 1997, Pages 99-109

  Miura, Hirohito ^a   Yanazawa, Masako ^a   Kato, Kentaro ^a,b   Kitamura, Kunio ^a  

^a MITSUBISHI KASEI INST OF LIFE SCI   (Japan)

^b UNIVERSITY OF HYOGO   (Japan)

Author keywords

Aristaless; Arx; Dlx1; Dorsal telencephalon; Floor plate; Ganglionic eminence; Homeobox gene; Mouse; Ventral thalamus; Zebrafish

Indexed keywords

HOMEODOMAIN PROTEIN;

ANIMAL CELL; ARTICLE; DIENCEPHALON; EMBRYO; FOREBRAIN; GENE EXPRESSION; HOMEOBOX; IN SITU HYBRIDIZATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; TELENCEPHALON; THALAMUS; ZEBRA FISH;

AMINO ACID SEQUENCE; ANIMALS; DIENCEPHALON; DROSOPHILA PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, HOMEOBOX; GENES, INSECT; INSECT PROTEINS; MICE; MOLECULAR SEQUENCE DATA; SEQUENCE ALIGNMENT; TELENCEPHALON; ZEBRAFISH;

ANIMALIA; DANIO RERIO; VERTEBRATA;

EID: 0031194810     PISSN: 09254773     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4773(97)00062-2     Document Type: Article

References (70)

1. -/- mutants due to a defective anterior neuroectoderm specification during gastrulation. Development 121, 3279-3290.
2. Akimenko, M.A., Ekker, M., Wegner, J., Lin, W. and Westerfield, M. (1994) Combinatorial expression of three zebrafish genes related to distal-less: part of a homeobox gene code for the head. J. Neurosci. 14, 3475-3486.
3. Ang, S.L. (1996) The brain organization. Nature 380, 25-27.
4. Ang, S.L., Jin, O., Rhinn, M., Daigle, N., Stevenson, L. and Rossant, J. (1996) A targeted mouse Otx2 mutation leads to severe defects in gastrulation and formation of axial mesoderm and to deletion of rostal brain. Development 122, 243-252.
5. Bally-Cuif, L. and Wassef, M. (1994) Ectopic induction and reorganization of Wnt-1 expression in quail/chick chimeras. Development 120, 3379-3394.
6. Barth, K.A. and Wilson, S.W. (1995) Expression of zebrafish nk2.2 is influenced by sonic hedgehog/vertebrate hedgehog-1 and demarcates a zone of neuronal differentiation in the embryonic forebrain. Development 121, 1755-1768.
7. Boncinelli, E., Gulisano, M. and Broccoli, V. (1993) Emx and Otx homeobox genes in the developing mouse brain. J. Neurobiol. 24, 1356-1366.
8. Bulfone, A., Kim, H.-J., Puelles, L., Porteus, M.H., Grippo, J.F. and Rubenstein, J.L.R. (1993a) The mouse Dlx-2 (Tes-1) gene is expressed in spatially restricted domains of the forebrain, face and limbs in midgestation mouse embryos. Mech. Dev. 40, 129-140.
9. Bulfone, A., Puelles, L., Porteus, M.H., Frohman, M.A., Martin, G.R. and Rubenstein, J.L.R. (1993b) Spatially restricted expression of Dlx-1, Dlx-2 (Tes-1), Gbx-2, and Wnt-3 in the embryonic day 12.5 mouse forebrain defines potential transverse and longitudinal segmental boundaries. J. Neurosci. 13, 3155-3172.
10. Bürglin, T.R. (1994) In: Duboule, D. (Ed.), Guidebook to the Homeobox Genes. Oxford University Press, London, pp. 27-71.
11. Chalepakis, G., Anastassia, S., Wijnholds, J., Tremblay, P. and Gruss, P. (1993) Pax: gene regulators in the developing nervous system. J. Neurobiol. 24, 1367-1384.
12. Chiang, C., Litingtung, Y., Lee, E., Young, K.E., Corden, J.L., Westphal, H. and Beachy, P.A. (1996) Cyclopla and defective axial patterning in mice lacking Sonic hedgehog gene function. Nature 383, 407-413.
13. Chomczynski, P. and Sacchi, N. (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162, 156-159.
14. Cohen, S.M. (1990) Specification of limb development in the Drosophila embryos by positional cues from segmentation genes. Nature 343, 173-177.
15. Cohen, S.M., Brönner, G., Küttner, F., Jürgens, G. and Jäckle, H. (1989) Distal-less encodes a homeodomain protein required for limb development in Drosophila. Nature 338, 432-434.
16. Cox, K.E., Deleon, D.V., Angerer, L.M. and Angerer, R.M. (1984) Detection of mRNAs in sea urchin embryos by in situ hybridization using asymmetric RNA probes. Dev. Biol. 101, 485-502.
17. Crossley, P.H., Martinez, S. and Martin, G.R. (1996) Midbrain development induced by FGF8 in the chick embryo. Nature 380, 66-68.
18. Danielian, P.S. and McMahon, A.P. (1996) Engrailed-1 as a target of the Wnt-1 signaling pathway in vertebrate midbrain development. Nature 383, 332-334.
19. Echelard, Y., Epstein, D.J., St-Jacques, B., Shen, L., Mohler, J., McMahon, J.A. and McMahon, A.P. (1993) Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity. Cell 75, 1417-1430.
20. Ericson, J., Muhr, J., Placzek, M., Lints, T., Jessell, T.M. and Edlund, T. (1995) Sonic hedgehog induces the differentiation of ventral forebrain neurons: a common signal for ventral patterning within the neural tube. Cell 81, 747-756.
21. Figdor, M.C. and Stern, C.D. (1993) Segmental organization of embryonic diencephalon. Nature 363, 630-634.
22. Finkelstein, R. and Boncinelli, E. (1994) From fly head to mammalian forebrain: the story of otd and Otx. Trends Genet. 10, 310-315.
23. Frantz, G.D., Weimann, J.M., Levin, M.E. and McConnell, S.K.J. (1994) Otx1 and Otx2 define layers and regions in developing cerebral cortex and cerebellum. J. Neurosci. 14, 5725-5740.
24. Hatini, V., Tao, W. and Lai, E. (1994) Expression of winged helix genes, BF-1 and BF-2, define adjacent domains within the developing forebrain and retina. J. Neurobiol. 25, 1293-1309.
25. Hatta, K. (1992) Role of the floor plate in axonal patterning in the zebrafish CNS. Neuron 9, 629-642.
26. Hatta, K., Kimmel, C.B., Ho, R.K. and Walker, C. (1991) The cyclops mutation blocks specification of the floor plate of the zebrafish central nervous system. Nature 350, 339-341.
27. Joyner, A.L. (1996) Engrailed, Wnt and Pax genes regulate midbrain-hindbrain development. Trends Genet. 12, 15-20.
28. Kennedy, T.E., Serafini, T., de la Torre, J.R. and Tessier-Lavigne, M. (1994) Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord. Cell 78, 425-435.
29. Krauss, S., Concordet, J.-P. and Ingham, P.W. (1993) A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish. Cell 75, 1431-1444.
30. Li, Y., Allende, M.L., Finkelstein, R. and Weinberg, E.S. (1994) Expression of two zebrafish orthodenticle-related genes in the embryonic brain. Mech. Dev. 48, 229-244.
31. Liu, I.S., Chen, J.D., Ploder, L., Vidgen, D., van der Kooy, D., Kalnins, V.I. and McInnes, R.R. (1994) Developmental expression of a novel murine homeobox gene (Chx10): evidence for roles in determination of the neuroretina and inner nuclear layer. Neuron 13. 377-393.
32. Macdonald, R., Xu, Q., Barth, K.A., Mikkola, I., Holder, N., Fjose, A., Krauss, S. and Wilson, S.W. (1994) Regulatory gene expression boundaries demarcate sites of neuronal differentiation in the embryonic zebrafish forebrain. Neuron 13, 1039-1053.
33. MacMaster, G.K. and Carmichael, G.G. (1977) Analysis of single- and double-stranded nucleic acids on polyacrylamide and agarose gels by using glyoxal and acridine orange. Proc. Natl. Acad. Sci. USA 74, 4835-4838.
34. Martí, E., Bumcrot, D.A., Takada, R. and McMahon, A.P. (1995) Requirement of 19K form of sonic hedgehog for induction of distinct ventral cell types in CNS explants. Nature 375, 322-325.
35. Mastick, G.S. and Easter, Jr., S.S. (1996) Initial organization of neurons and tracts in the embryonic mouse fore- and midbrain. Dev. Biol. 173, 79-94.
36. Matsuo, I., Kuratani, S., Kimura, C., Takeda, N. and Aizawa, S. (1995) Mouse Otx2 functions in the formation and patterning of rostral head. Genes Dev. 9, 2646-2658.
37. Mori, H., Miyazaki, Y., Morita, T., Nitta, H. and Mishina, M. (1994) Different spatio-temporal expression of three otx homeoprotein transcripts during zebrafish embryogenesis. Mol. Brain Res. 27, 221-231.
38. Nohno, T., Koyama, E., Myokai, F., Taniguchi, S., Ohuchi, H., Saito, T. and Noji, S. (1993) A chicken homeobox gene related to Drosophila paired is predominantly expressed in the developing limb. Dev. Biol. 158, 254-264.
39. Northcutt, R.G. and Kaas, J.H. (1995) The emergence and evolution of mammalian neocortex. Trends Neurosci. 18, 373-379.
40. Opstelten, D.J., Vogels, R., Robert, B., Kalkhoven, E., Zwartkruis, F., de Laaf, L., Destree, O.H., Deschamps, J., Lawson, K.A. and Meijlink, F. (1991) The mouse homeobox gene, S8, is expressed during embryogenesis predominantly in mesenchyme. Mech. Dev. 34, 29-41.
41. Placzek, M., Tessier-Lavigne, M., Jessell, T. and Dodd, J. (1990) Orientation of commissural axons in vitro in response to a floor plate-derived chemoattractant. Development 110, 19-30.
42. Placzek, M., Yamada, T., Tessier-Lavigne, M., Jessell, T. and Dodd, J. (1991) Control of dorsoventral pattern in vertebrate neural development: induction and polarising properties of the floor plate. Development 113 (Suppl.), 105-122.
43. Porteus, M.H., Bulfone, A., Liu, J.K., Puelles, L., Lo, L.C. and Rubenstein, J.L.R. (1994) Dlx-2, MASH-1, and MAP-2 expression and bromodeoxyuridine incorporation define molecularly distinct cell populations in the embryonic mouse forebrain. J. Neurosci. 14, 6370-6383.
44. Price, M. (1993) Members of the Dlx- and Nkx2-gene families are regionally expressed in the developing forebrain. J. Neurobiol. 24, 1385-1399.
45. Price, M., Lemaistre, M., Pischetola, M., Di Lauro, R. and Duboule, D. (1991) A mouse gene related to Distal-less shows a restricted expression in the developing forebrain. Nature 351, 748-751.
46. Puelles, L. and Rubenstein, J.L. (1993) Expression patterns of homeobox and other putative regulatory genes in the embryonic mouse forebrain suggest a neuromeric organization. Trends Neurosci. 16, 472-479.
47. Roelink, H., Augsbuger, A., Heemskerk, J., Korzh, V., Norlin, S., Ruizi Altaba, A., Tanabe, Y., Placzek, M., Edlund, T. and Jessell, T.M. (1994) Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord. Cell 76, 761-775.
48. Roelink, H., Porter, J.A., Chiang, C., Tanabe, Y., Chang, D.T., Beachy, P.A. and Jessell, T.M. (1995) Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis. Cell 81, 445-455.
49. Rubenstein, J.L.R., Martinez, S., Shimamura, K. and Puelles, L. (1994) The embryonic vertebrate forebrain: the prosomeric model. Science 266, 578-580.
50. Rudnick, A., Ling, T.Y., Odagiri, H., Rutter, W.J. and German, M.S. (1994) Pancreatic beta cells express a diverse set of homeobox genes. Proc. Natl. Acad. Sci. USA 91, 12203-12207.
51. Sasaki, H. and Hogan, B.L. (1994) HNF-3β as a regulator of floor plate development. Cell 76, 103-115.
52. Schneitz, K., Spielmann, P. and Noll, M. (1993) Molecular genetics of aristaless, a prd-type homeobox gene involved in the morphogenesis of proximal and distal pattern elements in a subset of appendages in Drosophila. Genes Dev. 7, 114-129.
53. Serafini, T., Kennedy, T.E., Galko, M.J., Mirzayan, C., Jessell, T.M. and Tessier-Lavigne, M. (1994) The netrins define a family of axon outgrowth-promoting proteins homologous to C, elegans UNC-6, Cell 78, 409-424.
54. Shimamura, K., Hartigan, D.J., Martinez, S., Puelles, L. and Rubenstein, J.L. (1995) Longitudinal organization of the anterior neural plate and neural tube. Development 121, 3923-3933.
55. Shirasaki, R., Tamada, A., Katsumata, R. and Murakami, F. (1995) Guidance of cerebellofugal axons in the rat embryo: directed growth toward the floor plate and subsequent elongation along the longitudinal axis. Neuron 14, 961-972.
56. Simeone, A., Acampora, M., Gulisano, A., Stornaiuolo, A. and Boncinelli, E. (1992a) Nested expression domains of four homeobox genes in developing rostral brain. Nature 358, 687-690.
57. Simeone, A., Gulisano, A., Acampora, D., Stornaiuolo, A., Rambaldi, M. and Boncinelli, E. (1992b) Two vertebrate homeobox genes related to the Drosophila empty spiracles gene are expressed in the embryonic cerebral cortex. EMBO J. 11, 2541-2550.
58. Simeone, A., Acampora, D., Mallamaci, A., Stornaiuolo, A., D'Apice, M.R., Nigro, V. and Boncinelli, E. (1993) A vertebrate gene related to orthodenticle contains a homeodomain of the bicoid class and demarcates anterior neuroectoderm in the gastrulating mouse embryo. EMBO J. 12, 2735-2747.
59. Simeone, A., D'Apice, M.R., Nigro, V., Casanova, J., Graziani, F., Acampora, D. and Avantaggiato, V. (1994) Orthopedia, a novel homeobox-containing gene expressed in the developing CNS of both mouse and Drosophila. Neuron 13, 83-101.
60. Tamada, A., Shirasaki, R. and Murakami, F. (1995) Floor plate chemoattracts crossed axons and chemorepels uncrossed axons in the vertebrate brain. Neuron 14, 1083-1093.
61. Tao, W. and Lai, E. (1992) Telencephalon-restricted expression of BF-1, a new member of the HNF-3/fork head gene family, in the developing rat brain. Neuron 8, 957-966.
62. Tessier-Lavigne, M., Placzek, M., Lumsden, A., Jessell, T. and Dodd, J. (1988) Chemotropic guidance of developing axons in the mammalian central nervous system. Nature 336, 775-778.
63. Walther, C. and Gruss, P. (1991) Pax-6, a murine paired box gene, is expressed in the developing CNS. Development 113, 1435-1449.
64. Webster, P.J. and Mansour, T.E. (1992) Conserved classes of homeodomain in Schistosoma mansoni, an early bilateral metazoan, Mech. Dev. 38, 25-32.
65. Wilkinson, D.G. (1993) In situ hybridization. In: Stern, C.D., Holland, P.W.H. (Eds.), Essential Developmental Biology. IRL Press, Oxford, pp. 257-274.
66. Xuan, S., Baptista, C.A., Balas, G., Tao, W., Soares, V.C. and Lai, E. (1995) Winged helix transcription factor BF-1 is essential for the development of the cerebral hemispheres. Neuron 14, 1141-1152.
67. Yamada, T., Placzek, M., Tanaka, H., Dodd, J. and Jessell, T.M. (1991) Control of cell pattern in the developing nervous system: polarizing activity of the floor plate and notochord. Cell 64, 635-647.
68. Yamada, T., Pfaff, S.L., Edlund, T. and Jessell, T.M. (1993) Control of cell pattern in the neural tube: motor neuron induction by diffusible factors from notochord and floor plate. Cell 73, 673-686.
69. Zellmer, E., Zhang, Z., Greco, D., Rhodes, J., Cassel, S. and Lewis, E.J. (1995) A homeodomain protein selectively expressed in noradrenergic tissue regulates transcription of neurotransmitter biosynthetic genes. J. Neurosci. 15, 8109-8120.
70. Zhao, G.Q., Zhou, X., Eberspaecher, H., Solursh, M. and de Crombrugghe, B. (1993) Cartilage homeoprotein 1, a homeoprotein selectively expressed in chondrocytes. Proc. Natl. Acad. Sci. USA 90, 8633-8637.