MCP-1 induces activation of MAP-kinases ERK, JNK and p38 MAPK in human endothelial cells

Cardiovascular Research

Volumn 56, Issue 2, 2002, Pages 284-292

  Werle, Martina ^a   Schmal, Ulrike ^a   Hanna, Katharina ^a   Kreuzer, Jörg ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Atherosclerosis; Endothelial function; Signal transduction

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; GELATINASE B; ISOENZYME; MITOGEN ACTIVATED PROTEIN KINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN;

ARTICLE; CELL STIMULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME KINETICS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN SECRETION; TIME;

CELL CULTURE TECHNIQUES; CHEMOKINE CCL2; ENDOTHELIUM, VASCULAR; GENE EXPRESSION; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RECEPTORS, CHEMOKINE; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 0036838917     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(02)00600-4     Document Type: Article

References (36)

1. Rollins B.J. Monocyte chemoattractant protein 1: a potential regulator of monocyte recruitment in inflammatory disease. Mol. Med. Today. 2:1996;198-204.
2. Terkeltaub R., Boisvert W.A., Curtiss L.K. Chemokines and atherosclerosis. Curr. Opin. Lipidol. 9:1998;397-405.
3. Taub D.D., Ortaldo J.R., Turcovski-Corrales S.M., et al. Beta chemokines costimulate lymphocyte cytolysis, proliferation and lymphokine production. J. Leukoc. Biol. 59:1996;81-89.
4. Denger S., Jahn L., Wende P., et al. Expression of monocyte chemoattractant protein-1 cDNA in vascular smooth muscle cells: induction of the synthetic phenotype: a possible clue to SMC differentiation in the process of atherogenesis. Atherosclerosis. 144:1999;15-23.
5. Reape T.J., Groot P.H. Chemokines and atherosclerosis. Atherosclerosis. 147:1999;213-225.
6. Charo I.F., Myers S.J., Herman A., et al. Molecular cloning and functional expression of two monocyte chemoattractant protein 1 receptors reveals alternative splicing of the carboxyl-terminal tails. Proc. Natl. Acad. Sci. USA. 91:1994;2752-2756.
7. Kelvin D.J., Michiel D.F., Johnston J.A., et al. Chemokines and serpentines: the molecular biology of chemokine receptors. J. Leukoc. Biol. 54:1993;604-612.
8. Dawson T.C., Kuziel W.A., Osahar T.A., Maeda N. Absence of CC chemokine receptor-2 reduces atherosclerosis in apolipoprotein E-deficient mice. Atherosclerosis. 143:1999;205-211.
9. Boring L., Gosling J., Cleary M., Charo I.F. Decreased lesion formation in CCR2-/- mice reveals a role for chemokines in the initiation of atherosclerosis. Nature. 394:1998;894-897.
10. Hayes I.M., Jordan N.J., Towers S., et al. Human vascular smooth muscle cells express receptors for CC chemokines. Arterioscler. Thromb. Vasc. Biol. 18:1998;397-403.
11. Weber K.S., Nelson P.J., Grone H.J., Weber C. Expression of CCR2 by endothelial cells: implications for MCP-1 mediated wound injury repair and in vivo inflammatory activation of endothelium. Arterioscler. Thromb. Vasc. Biol. 19:1999;2085-2093.
12. Bokemeyer D., Sorokin A., Dunn M.J. Multiple intracellular MAP kinase signaling cascades. Kidney Int. 49:1996;1187-1198.
13. Whitmarsh A.J., Davis R.J. Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways. J. Mol. Med. 74:1996;589-607.
14. Jaffe E.A., Nachman R.L., Becker C.G., Minick C.R. Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. J. Clin. Invest. 52:1973;2745-2756.
15. Viedt C., Soto U., Krieger-Brauer H.I., et al. Differential activation of mitogen-activated protein kinases in smooth muscle cells by angiotensin II: involvement of p22phox and reactive oxygen species. Arterioscler. Thromb. Vasc. Biol. 20:2000;940-948.
16. Cambien B., Pomeranz M., Millet M.A., et al. Signal transduction involved in MCP-1-mediated monocytic transendothelial migration. Blood. 97:2001;359-366.
17. McCawley L.J., Li S., Wattenberg E.V., Hudson L.G. Sustained activation of the mitogen-activated protein kinase pathway. A mechanism underlying receptor tyrosine kinase specificity for matrix metalloproteinase-9 induction and cell migration. J. Biol. Chem. 274:1999;4347-4353.
18. Dubois P.M., Palmer D., Webb M.L., et al. Early signal transduction by the receptor to the chemokine monocyte chemotactic protein-1 in a murine T cell hybrid. J. Immunol. 156:1996;1356-1361.
19. Myers S.J., Wong L.M., Charo I.F. Signal transduction and ligand specificity of the human monocyte chemoattractant protein-1 receptor in transfected embryonic kidney cells. J. Biol. Chem. 270:1995;5786-5792.
20. Yen H., Zhang Y., Penfold S., Rollins B.J. MCP-1-mediated chemotaxis requires activation of nonoverlapping signal transduction pathways. J. Leukoc. Biol. 61:1997;529-532.
21. Ohanian J., Cunliffe P., Ceppi E., et al. Activation of p38 mitogen-activated protein kinases by endothelin and noradrenaline in small arteries, regulation by calcium influx and tyrosine kinases, and their role in contraction. Arterioscler. Thromb. Vasc. Biol. 21:2001;1921-1927.
22. Roulston A., Reinhard C., Amiri P., Williams L.T. Early activation of c-Jun N-terminal kinase and p38 kinase regulate cell survival in response to tumor necrosis factor α J. Biol. Chem. 273:1998;10232-10239.
23. Parissis J.T., Adamopoulos S., Venetsanou K.F., et al. Serum profiles of C-C chemokines in acute myocardial infarction: possible implication in postinfarction left ventricular remodeling. J. Interferon Cytokine Res. 22:2002;223-229.
24. Luttrell L.M., van Biesen T., Hawes B.E., et al. G-protein-coupled receptors and their regulation: activation of the MAP kinase signaling pathway by G-protein-coupled receptors. Adv. Second Messenger Phosphoprotein Res. 31:1997;263-277.
25. Kuang Y., Wu Y., Jiang H., Wu D. Selective G protein coupling by C-C chemokine receptors. J. Biol. Chem. 271:1996;3975-3978.
26. Tsao P.S., Wang B., Buitrago R., et al. Nitric oxide regulates monocyte chemotactic protein-1. Circulation. 96:1997;934-940.
27. Gawaz M., Neumann F.J., Dickfeld T., et al. Activated platelets induce monocyte chemotactic protein-1 secretion and surface expression of intercellular adhesion molecule-1 on endothelial cells. Circulation. 98:1998;1164-1171.
28. Gum R., Lengyel E., Juarez J., et al. Stimulation of 92-kDa gelatinase B promoter activity by ras is mitogen-activated protein kinase kinase 1-independent and requires multiple transcription factor binding sites including closely spaced PEA3/ets and AP-1 sequences. J. Biol. Chem. 271:1996;10672-10680.
29. Genersch E., Hayess K., Neuenfeld Y., Haller H. Sustained ERK phosphorylation is necessary but not sufficient for MMP-9 regulation in endothelial cells: involvement of Ras-dependent and -independent pathways. J. Cell. Sci. 113:(Pt 23):2000;4319-4330.
30. Wang H., Keiser J.A. Hepatocyte growth factor enhances MMP activity in human endothelial cells. Biochem Biophys Res Commun. 272:2000;900-905.
31. Zeigler M.E., Chi Y., Schmidt T., Varani J. Role of ERK and JNK pathways in regulating cell motility and matrix metalloproteinase 9 production in growth factor-stimulated human epidermal keratinocytes. J. Cell. Physiol. 180:1999;271-284.
32. Taraboletti G., D'Ascenzo S., Borsotti P., et al. Shedding of the matrix metalloproteinases MMP-2, MMP-9 and MT1-MMP as membrane vesicle-associated components by endothelial cells. Am. J. Pathol. 160:2002;673-680.
33. Ikeda U., Shimpo M., Ohki R., et al. Fluvastatin inhibits matrix metalloproteinase-1 expression in human vascular endothelial cells. Hypertension. 36:2000;325-329.
34. Duhamel-Clerin E., Orvain C., Lanza F., et al. Thrombin receptor-mediated increase of two matrix metalloproteinases, MMP-1 and MMP-3, in human endothelial cells. Arterioscler. Thromb. Vasc. Biol. 17:1997;1931-1938.
35. Yamamoto T., Eckes B., Mauch C., et al. Monocyte chemoattractant protein-1 enhances gene expression and synthesis of matrix metalloproteinase-1 in human fibroblasts by an autocrine IL-1 α loop. J. Immunol. 164:2000;6174-6179.
36. Libby P., Sukhova G., Lee R.T., Galis Z.S. Cytokines regulate vascular functions related to stability of the atherosclerotic plaque. J. Cardiovasc. Pharmacol. 25:1995;S9-12.